Publications

1. Ge Ma, Ping-Ying Pan, Samuel Eisenstein, Celia M Divino, Clifford A. Lowell, Toshiyuki Takai and Shu-Hsia Chen*, 2011 Paired Immunoglobin Like Receptor-B regulates the suppressive function and fate of myeloid derived suppressor cells. Immunity, Mar 25;34(3):385-95. (Cover future for that issue) PMID:21376641 PMCID: PMC3064726.

2. Peng S, Ma B, Chen SH, Hung CF, Wu T. 2011 DNA vaccines delivered by human papillomavirus pseudovirions as a promising approach for generating antigen-specific CD8+ T cell immunity. Cell Biosci. Jul 28;1:26.

3. Kao J, Ko EC, Eisenstein S, Sikora AG, Fu S, Chen SH*. 2011 Targeting immune suppressing myeloid-derived suppressor cells in oncology. Crit Rev Oncol Hematol. Jan;77(1):12-9.

4. Gobind Singh, Daigo Hashimoto, Xiaocai Yan, Julie Helft, Ge Ma, Rui F Qiao, Colin R Kennedy, Shu-Hsia Chen, Miriam Merad, and Andrew M Chan, 2012, R-Ras is required for murine dendritic cell maturation and CD4+ T-cell activation, Blood.  Feb 16;119(7):1693-701. PMID: 22174156, PMCID: PMC3286347

5. Jayaraman P, Parikh F, Lopez-Rivera E, Hailemichael Y, Clark A, Ma G, Cannan D, Ramacher M, Kato M, Overwijk WW, Chen SH, Umansky VY, Sikora AG. 2012 Tumor-Expressed Inducible Nitric Oxide Synthase Controls Induction of Functional Myeloid-Derived Suppressor Cells through Modulation of Vascular Endothelial Growth Factor Release. J Immunol. Jun 1;188(11):5365-76. Epub 2012 Apr 23. PMID: 22529296, PMCID: PMC3358566

6. Ochando JC, Chen SH*. 2012 Myeloid-derived suppressor cells in transplantation and cancer. Immunol Res. Apr 26. PMID: 22535241

7. Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang C, Hyunh H, Kang X, Silvany R, Wan X, Ye J, Cantó AP, Chen SH, Wang HY, Ward ES, Zhang CC. 2012 Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development. Nature. May 30;485(7400):656-60. PMID: 22660330 PMCID: PMC3367397

8. Ping-Ying Pan,Ge Ma, and Shu-Hsia Chen*, 2012 Innate and adaptive immune regulation and Cancer immunotherapy, Editor: Rongfu Wang, Baylor College of Medicine, chapter topic on: Myeloid-Derived Suppressor Cells in Cancer. Chapter book.

9. Fu S, Yang Y, Tirtha D, Yen Y, Zhou BS, Zhou MM, Ohlmeyer M, Ko EC, Cagan R, Rosenstein BS, Chen SH, Kao J. 2012 γ-H2AX Kinetics as a Novel Approach to High Content Screening for Small Molecule Radiosensitizers. PLoS One.;7(6):e38465. Epub 2012 Jun 29. PMID: 22768044

10. Tong CC, Ko EC, Sung MW, Cesaretti JA, Stock RG, Packer SH, Forsythe K, Genden EM, Schwartz M, Lau KH, Galsky M, Ozao-Choy J, Chen SH, Kao J. 2012 Phase II Trial of Concurrent Sunitinib and Image-Guided Radiotherapy for Oligometastases. PLoS One.;7(6):e36979. Epub 2012 Jun 27. PMID: 22761653

11. Peter Svider, Shu-Hsia Chen* and Andy Sikora* 2013 The Tumor Immunoenvironment Chapter 24: Programming of MDSC: New Opportunities for Targeted Therapy. Editors: Michael R. Shurin, Viktor Umansky & Anatoli  M. Malyguine

12. Wen-Chin Yang, Ge Ma, Shu-Hsia Chen*, and Ping-Ying Pan*, 2013 Polarization and Reprogramming of myeloid-derived suppressor cells: mechanism, function and therapy, J Mol Cell Biol. 2013, Jun;5(3):207-9. PMID: 23532593

13. Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ, Kreisel D, Swartz MA, Sorci-Thomas MG, Randolph GJ. 2013 Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. J Clin Invest. Apr 1;123(4):1571-9.

14. Samuel Eisenstein, Brian A. Coakley, Karen Briley-Saebo, Ge Ma, Marcia Meseck, Stephen Ward, Celia Divino, Savio Woo, Shu-Hsia Chen*, Ping-Ying Pan*. 2013 A novel role of myeloid derived suppressor cells for tumor-specific therapeutic targeting Cancer Research, 2013, 73(16):5003-15. [Epub ahead of print] PMID: 23536556.

15. T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation. Jianjun Yang, Zhang R, Lu G, Shen Y, Peng L, Zhu C, Cui M, Wang W, Arnaboldi P, Tang M, Gupta M, Qi CF, Jayaraman P, Zhu H, Jiang B, Chen SH, He JC, Ting AT, Zhou MM, Kuchroo VK, Morse HC 3rd, Ozato K, Sikora AG, Xiong H. J Exp Med. 2013 Jul 1;210(7):1447-62.

16. Ping-Ying Pan, Hui-Ming Chen, and Shu-Hsia Chen* 2013 Myeloid-derived suppressor cell as a Trojan horse: a cellular vehicle with cytotoxicity for delivery of oncolytic virus. Oncoimmunology, 2013 2:8.

17. Wang Y, Chen K, Wu Z, Liu Y, Liu S, Zou Z, Chen SH, Qu C. Immunizations with hepatitis B viral antigens and a TLR7/8 agonist adjuvant induce antigen-specific immune responses in HBV-transgenic mice. Int J Infect Dis. 2014 Dec; 29:31-6. doi: 10.1016/j.ijid.2014.07.015. Epub 2014 Oct 23. PMID: 25449231

18. Samuel Eisenstein, Shu-Hsia Chen*, Ping-Ying Pan*, 2014 Immune cells: more than simple carriers for systemic delivery of oncolytic viruses. Oncolytic Virotherapy. November 2014 Volume 2014:3 Pages 83—91.  http://dx.doi.org/10.2147/OV.S47143

19. Eric C Ko, MD, PhD; Ge Ma, MD; Sam Eisenstein, MD; Brian Coakley, MD; Junko Ozao-Choy, MD; Ping-Ying Pan Ph D; Johnny Kao, MD; Shu-hsia Chen*, PhD 2015 Myeloid-derived suppressor cells (MDSCs) and lymphocyte subsets in patients with oligometastases treated with sunitinib and hypofractionated image-guided radiation therapy (IGRT): Implications for immunomonitoring and immunotherapy, Clinical Cancer Research, Apr 28. PMID: 25922428

20. DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, Brahmachary M, Chen HM, Boros P, Rausell-Palamos F, Yun TJ, Riquelme P, Rastrojo A, Aguado B, Stein-Streilein J, Tanaka M, Zhou L, Zhang J, Lowary TL, Ginhoux F, Park CG, Cheong C, Brody J, Turley SJ, Lira SA, Bronte V, Gordon S, Heeger PS, Merad M, Hutchinson J, Chen SH, Ochando J. Immunity. 2015 Jun 16;42(6):1143-58. PMID: 26070485

21. 5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation.
Wang J, Peng L, Zhang R, Zheng Z, Chen C, Cheung KL, Cui M, Bian G, Xu F, Chiang D, Hu Y, Chen Y, Lu G, Yang J, Zhang H, Yang J, Zhu H, Chen SH, Liu K, Zhou MM, Sikora AG, Li L, Jiang B, Xiong H. Oncotarget. 2016 Mar 24. doi: 10.18632/oncotarget.8344.  PMID: 27027355

Complete List of Publications