Ge Ma, Ping-Ying Pan, Samuel Eisenstein, Celia M Divino, Clifford A. Lowell, Toshiyuki Takai and Shu-Hsia Chen
Paired Immunoglobin Like Receptor-B regulates the suppressive function and fate of myeloid derived suppressor cells.
Immunity, Mar 25;34(3):385-95. (Cover future for that issue) PMID:21376641 PMCID: PMC3064726.
Peng S, Ma B, Chen SH, Hung CF, Wu T.
DNA vaccines delivered by human papillomavirus pseudovirions as a promising approach for generating antigen-specific CD8+ T cell immunity.
Cell Biosci. Jul 28;1:26.
Kao J, Ko EC, Eisenstein S, Sikora AG, Fu S, Chen SH
Targeting immune suppressing myeloid-derived suppressor cells in oncology.
Crit Rev Oncol Hematol. Jan;77(1):12-9.
Gobind Singh, Daigo Hashimoto, Xiaocai Yan, Julie Helft, Ge Ma, Rui F Qiao, Colin R Kennedy, Shu-Hsia Chen, Miriam Merad, and Andrew M Chan
R-Ras is required for murine dendritic cell maturation and CD4+ T-cell activation, Blood.
Feb 16;119(7):1693-701. PMID: 22174156, PMCID: PMC3286347
Jayaraman P, Parikh F, Lopez-Rivera E, Hailemichael Y, Clark A, Ma G, Cannan D, Ramacher M, Kato M, Overwijk WW, Chen SH, Umansky VY, Sikora AG.
Tumor-Expressed Inducible Nitric Oxide Synthase Controls Induction of Functional Myeloid-Derived Suppressor Cells through Modulation of Vascular Endothelial Growth Factor Release.
J Immunol. Jun 1;188(11):5365-76. Epub 2012 Apr 23. PMID: 22529296, PMCID: PMC3358566
Ochando JC, Chen SH
Myeloid-derived suppressor cells in transplantation and cancer.
Immunol Res. Apr 26. PMID: 22535241
Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang C, Hyunh H, Kang X, Silvany R, Wan X, Ye J, Cantó AP, Chen SH, Wang HY, Ward ES, Zhang CC.
Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development.
Nature. May 30;485(7400):656-60. PMID: 22660330 PMCID: PMC3367397
Ping-Ying Pan,Ge Ma, and Shu-Hsia Chen
Innate and adaptive immune regulation and Cancer immunotherapy
Editor: Rongfu Wang, Baylor College of Medicine, chapter topic on: Myeloid-Derived Suppressor Cells in Cancer. Chapter book.
Fu S, Yang Y, Tirtha D, Yen Y, Zhou BS, Zhou MM, Ohlmeyer M, Ko EC, Cagan R, Rosenstein BS, Chen SH, Kao J.
γ-H2AX Kinetics as a Novel Approach to High Content Screening for Small Molecule Radiosensitizers.
PLoS One.;7(6):e38465. Epub 2012 Jun 29. PMID: 22768044
Tong CC, Ko EC, Sung MW, Cesaretti JA, Stock RG, Packer SH, Forsythe K, Genden EM, Schwartz M, Lau KH, Galsky M, Ozao-Choy J, Chen SH, Kao J.
Phase II Trial of Concurrent Sunitinib and Image-Guided Radiotherapy for Oligometastases.
PLoS One.;7(6):e36979. Epub 2012 Jun 27. PMID: 22761653
Peter Svider, Shu-Hsia Chen* and Andy Sikora*
The Tumor Immunoenvironment Chapter 24: Programming of MDSC: New Opportunities for Targeted Therapy.
Editors: Michael R. Shurin, Viktor Umansky & Anatoli M. Malyguine.
Wen-Chin Yang, Ge Ma, Shu-Hsia Chen*, and Ping-Ying Pan*
Polarization and Reprogramming of myeloid-derived suppressor cells: mechanism, function and therapy
J Mol Cell Biol. 2013, Jun;5(3):207-9. PMID: 23532593
Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ, Kreisel D, Swartz MA, Sorci-Thomas MG, Randolph GJ.
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice.
J Clin Invest. Apr 1;123(4):1571-9.
Samuel Eisenstein, Brian A. Coakley, Karen Briley-Saebo, Ge Ma, Marcia Meseck, Stephen Ward, Celia Divino, Savio Woo, Shu-Hsia Chen*, Ping-Ying Pan*
A novel role of myeloid derived suppressor cells for tumor-specific therapeutic targeting Cancer Research
2013, 73(16):5003-15. [Epub ahead of print] PMID: 23536556.
Jianjun Yang, Zhang R, Lu G, Shen Y, Peng L, Zhu C, Cui M, Wang W, Arnaboldi P, Tang M, Gupta M, Qi CF, Jayaraman P, Zhu H, Jiang B, Chen SH, He JC, Ting AT, Zhou MM, Kuchroo VK, Morse HC 3rd, Ozato K, Sikora AG, Xiong H.
T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation.
J Exp Med. 2013 Jul 1;210(7):1447-62.
Ping-Ying Pan, Hui-Ming Chen, and Shu-Hsia Chen*
Myeloid-derived suppressor cell as a Trojan horse: a cellular vehicle with cytotoxicity for delivery of oncolytic virus.
Oncoimmunology, 2013 2:8.
Wang Y, Chen K, Wu Z, Liu Y, Liu S, Zou Z, Chen SH, Qu C.
Immunizations with hepatitis B viral antigens and a TLR7/8 agonist adjuvant induce antigen-specific immune responses in HBV-transgenic mice.
Int J Infect Dis. 2014 Dec; 29:31-6. doi: 10.1016/j.ijid.2014.07.015. Epub 2014 Oct 23. PMID: 25449231
Samuel Eisenstein, Shu-Hsia Chen*, Ping-Ying Pan*
Immune cells: more than simple carriers for systemic delivery of oncolytic viruses.
Oncolytic Virotherapy. November 2014 Volume 2014:3 Pages 83—91. http://dx.doi.org/10.2147/OV.S47143
Eric C Ko, MD, PhD; Ge Ma, MD; Sam Eisenstein, MD; Brian Coakley, MD; Junko Ozao-Choy, MD; Ping-Ying Pan Ph D; Johnny Kao, MD; Shu-hsia Chen*
Myeloid-derived suppressor cells (MDSCs) and lymphocyte subsets in patients with oligometastases treated with sunitinib and hypofractionated image-guided radiation therapy (IGRT): Implications for immunomonitoring and immunotherapy
Clinical Cancer Research, Apr 28. PMID: 25922428
Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, Brahmachary M, Chen HM, Boros P, Rausell-Palamos F, Yun TJ, Riquelme P, Rastrojo A, Aguado B, Stein-Streilein J, Tanaka M, Zhou L, Zhang J, Lowary TL, Ginhoux F, Park CG, Cheong C, Brody J, Turley SJ, Lira SA, Bronte V, Gordon S, Heeger PS, Merad M, Hutchinson J, Chen SH, Ochando J.
DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance.
Immunity. 2015 Jun 16;42(6):1143-58. PMID: 26070485
Wang J, Peng L, Zhang R, Zheng Z, Chen C, Cheung KL, Cui M, Bian G, Xu F, Chiang D, Hu Y, Chen Y, Lu G, Yang J, Zhang H, Yang J, Zhu H, Chen SH, Liu K, Zhou MM, Sikora AG, Li L, Jiang B, Xiong H.
5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation.
Oncotarget. 2016 Mar 24. doi: 10.18632/oncotarget.8344. PMID: 27027355