Selected Publications:
2016
Mapping of internal monophosphate 5’ ends of Bacillus subtilis messenger RNAs and ribosomal RNAs in wild-type and ribonuclease-mutant strains.
Jeanne M. DiChiara, Bo Liu, Sabine Figaro, Ciarán Condon, and David H. Bechhofer
Nucleic Acids Research. 2016 Apr 20;44(7):3373-89. doi: 10.1093/nar/gkw073. Epub 2016 Feb 15.
Expression of multiple Bacillus subtilis genes is controlled by decay of slrA mRNA from Rho-dependent 3’ ends.
Bo Liu, Daniel B. Kearns, and David H. Bechhofer
Nucleic Acids Research. 2016 Apr 20;44(7):3364-72. doi: 10.1093/nar/gkw069. Epub 2016 Feb 8.
Interaction of Bacillus subtilis Polynucleotide Phosphorylase and RNase Y: Structural Mapping and Effect on mRNA Turnover.
Elizabeth Salvo, Shanique Alabi, Bo Liu, Avner Schlessinger, and David H. Bechhofer
The Journal of Biological Chemistry. 2016 Mar 25;291(13):6655-63. doi: 10.1074/jbc.M115.711044. Epub 2016 Jan 21.
2015
Clinically Relevant Small Group Discussions in a First Semester Medical School Molecular Science Course – Module 1: Sickle Cell Anemia.
Green R, Landau E, and Bechhofer DH.
MedEd PORTAL in press.
Small stable RNA maturation and turnover in Bacillus subtilis.
Gilet L, DiChiara JM, Figaro S, Bechhofer DH, Condon C.
Molecular Microbiology. 2015 Jan;95(2):270-82. Epub 2014 Dec 19.
2014
Global analysis of mRNA decay intermediates in Bacillus subtilis wild-type and polynucleotide phosphorylase-deletion strains.
Liu B, Deikus G, Bree A, Durand S, Kearns DB, Bechhofer DH.
Molecular Microbiology. 2014 Oct;94(1):41-55. Epub 2014 Aug 21.
2013
Nucleotide specificity in bacterial mRNA recycling.
Bechhofer DH.
Proceedings of the National Academy of Sciences U S A. 2013 May 28;110(22):8765-6. Epub 2013 May 13. No abstract available.
2011
Decay of a model mRNA in Bacillus subtilis by a combination of RNase J1 5′ exonuclease and RNase Y endonuclease activities.
Yao S, Richards J, Belasco JG, Bechhofer DH.
Journal of Bacteriology. 2011 Nov;193(22):6384-6. Epub 2011 Sep 9.
5′ End-independent RNase J1 endonuclease cleavage of Bacillus subtilis model RNA.
Deikus G, Bechhofer DH.
Journal of Biological Chemistry. 2011 Oct 7;286(40):34932-40. Epub 2011 Aug 23.
An RNA pyrophosphohydrolase triggers 5′-exonucleolytic degradation of mRNA in Bacillus subtilis.
Richards J, Liu Q, Pellegrini O, Celesnik H, Yao S, Bechhofer DH, Condon C, Belasco JG.
Molecular Cell. 2011 Sep 16;43(6):940-9.
Bacillus subtilis mRNA decay: new parts in the toolkit.
Bechhofer DH.
Wiley Interdiscip Reviews: RNA. 2011 May-Jun;2(3):387-94. Epub 2010 Dec 16. Review.
Regulated RNA stability in the Gram positives.
Condon C, Bechhofer DH.
Current Opinion in Microbiology. 2011 Apr;14(2):148-54. Epub 2011 Feb 19. Review.
2010
Initiation of decay of Bacillus subtilis rpsO mRNA by endoribonuclease RNase Y.
Yao S, Bechhofer DH.
Journal of Bacteriology. 2010 Jul;192(13):3279-86. Epub 2010 Apr 23.