Selected Publications

For the full list of Dr. Basler’s publications: Basler Bibliography

Batra J, Hultquist JF, Liu D, Shtanko O, J. VD, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, Haas P, Schmidt CB, Schlesinger S, LaCount DJ, Dave RA, Amarasinghe GK, Basler CF*, Krogan NJ*. Protein interaction mapping identifies RBBP6 as a negative regulator of Ebola virus replication. Cell. 2018 Dec. 13; 175 (7):917-1930. *Co-corresponding authors

Williams CG, Gibbons JS, Keiffer TR, Luthra P, Edwards MR, Basler CF. Impact of Mengla Virus Proteins on Human and Bat Innate Immune Pathways. J Virol. 2020;94(13). PMCID: PMC7307173.

Woolsey C, Menicucci AR, Cross RW, Luthra P, Agans KN, Borisevich V, Geisbert JB, Mire CE, Fenton KA, Jankeel A, Anand S, Ebihara H, Geisbert TW, Messaoudi I, Basler CF. A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge. Cell Reports. 2019;28(12):3032-46.e6. doi: 10.1016/j.celrep.2019.08.047.

Satterfield BA, Borisevich V, Foster SL, Rodriguez SE, Cross RW, Fenton KA, Agans KN, Basler CF, Geisbert TW, Mire CE. Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model. Sci Rep. 2019;9(1):16710-. doi: 10.1038/s41598-019-53037-0. PubMed PMID: 31723221.

Edwards MR, Liu G, De S, Sourimant J, Pietzsch C, Johnson B, Amarasinghe GK, Leung DW, Bukreyev A, Plemper RK, Aron Z, Bowlin TL, Moir DT, Basler CF. Small Molecule Compounds That Inhibit Antioxidant Response Gene Expression in an Inducer-Dependent Manner. ACS Infect Dis. 2020;6(3):489-502. doi: 10.1021/acsinfecdis.9b00416. Epub 2020 Jan 15.

Williams CG, Gibbons JS, Keiffer TR, Luthra P, Edwards MR, Basler CF. Impact of Mengla virus proteins on human and bat innate immune pathways. J Virol. 2020. pr 15:JVI.00191-20. doi: 10.1128/JVI.00191-20.

Edwards MR, Hoad M, Tsimbalyuk S, Menicucci AR, Messaoudi I, Forwood JK, Basler CF. Henipavirus W proteins interact with 14-3-3 to modulate host gene expression. J Virol. 2020. Apr 22:JVI.00373-20. doi: 10.1128/JVI.00373-20.

Jureka AS, Silvas JA, Basler CF. Propagation, Inactivation, and Safety Testing of SARS-CoV-2. Viruses. 2020;12(6). Epub 2020/06/11. doi: 10.3390/v12060622. PubMed PMID: 32517266; PMCID: PMC7354523.

Luthra P, Anantpadma M, De S, Sourimant J, Davey RA, Plemper RK, Basler CF. High-Throughput Screening Assay to Identify Small Molecule Inhibitors of Marburg Virus VP40 Protein. ACS Infect Dis. 2020;6(10):2783-99. DOI: 10.1021/acsinfecdis.0c00512.

Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O’Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Huttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbolle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR, 3rd, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH, Jr., Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D, Consortium QSB, Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL, Zoonomia C, Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, Shoichet B, Ott M, Palmarini M, Shokat KM, Garcia-Sastre A*, Rassen JA, Grosse R*, Rosenberg OS*, Verba KA*, Basler CF*, Vignuzzi M*, Peden AA*, Beltrao P*, Krogan NJ*. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science. 2020. 10.1126/science.abe9403  *Co-corresponding authors

Keiffer TR, Ciancanelli MJ, Edwards MR, Basler CF. Interactions of the Nipah Virus P, V, and W Proteins across the STAT Family of Transcription Factors. mSphere. 2020;5(6). PMCID: PMC7771230.

Jagga B, Edwards M, Pagin M, Wagstaff KM, Aragao D, Roman N, Nanson JD, Raidal SR, Dominado N, Stewart M, Jans DA, Hime GR, Nicolis SK, Basler CF, Forwood JK. Structural basis for nuclear import selectivity of pioneer transcription factor SOX2. Nat Commun. 2021;12(1):28. PMCID: PMC7782513.

Jureka AS, Williams CG, Basler CF. Pulsed Broad-Spectrum UV Light Effectively Inactivates SARS-CoV-2 on Multiple Surfaces and N95 Material. Viruses. 2021;13(3):460.

Sweeney-Gibbons J, Khadka S, Williams CG, Wang L, Schneller SW, Liu C, Tufariello JM, Basler CF. Mechanisms of anti-vesicular stomatitis virus activity of deazaneplanocin and its 3-brominated analogues. Antiviral Res. 2021 May 18:105088. doi: 10.1016/j.antiviral.2021.105088.

Batra J, Mori H, Small GI, Anantpadma M, Shtanko O, Mishra N, Zhang M, Liu D, Williams CG, Biedenkopf N, Becker S, Gross ML, Leung DW, Davey RA, Amarasinghe GK, Krogan NJ, Basler CF. Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection. Embo J. 2021:e105658. Epub 2021/07/15. doi: 10.15252/embj.2020105658. PubMed PMID: 34260076.

Khadka S, Williams CG, Sweeney-Gibbons J, Basler CF. 3’ untranslated regions of Marburg and Ebola virus mRNAs possess negative regulators of translation that are modulated by ADAR1 editing. J Virol. 2021 Aug 4:JVI0065221. doi: 10.1128/JVI.00652-21. PMID: 34346762

Williams CG, Jureka AS, Silvas JA, Nicolini AM, Chvatal SA, Carlson-Stevermer J, Oki J, Holden K, Basler CF. Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication. Cell Reports. 2021 Jul 20;109479. doi: 10.1016/j.celrep.2021.109479.

El-Sayed NS, Jureka AS, Edwards MR, Lohan S, Williams CG, Keiser PT, Davey RA, Totonchy J, Tiwari RK, Basler CF, Parang K. Synthesis and antiviral activity of fatty acyl conjugates of remdesivir against severe acute respiratory syndrome coronavirus 2 and Ebola virus. Eur J Med Chem. 2021;226:113862. Epub 2021/09/29. doi: 10.1016/j.ejmech.2021.113862. PubMed PMID: 34583312; PMCID: PMC8454092.

Wang L, Asare E, Shetty AC, Sanchez-Tumbaco F, Edwards MR, Saranathan R, Weinrick B, Xu J, Chen B, Benard A, Dougan G, Leung DW, Amarasinghe GK, Chan J, Basler CF, Jacobs WR, Jr., Tufariello JM. Multiple genetic paths including massive gene amplification allow Mycobacterium tuberculosis to overcome loss of ESX-3 secretion system substrates. Proc Natl Acad Sci U S A. 2022;119(8). Epub 2022/02/24. doi: 10.1073/pnas.2112608119. PubMed PMID: 35193958; PMCID: PMC8872769.

Munasinghe TS, Edwards MR, Tsimbalyuk S, Vogel OA, Smith KM, Stewart M, Foster JK, Bosence LA, Aragao D, Roby JA, Basler CF*, Forwood JK*. MERS-CoV ORF4b employs an unusual binding mechanism to target IMPalpha and block innate immunity. Nat Commun. 2022;13(1):1604. Epub 2022/03/27. doi: 10.1038/s41467-022-28851-2. PubMed PMID: 35338144; PMCID: PMC8956657. *Co-corresponding authors

Jureka AS, Basler CF. Propagation and Quantification of SARS-CoV-2. Methods Mol Biol. 2022;2452:111-29. Epub 2022/05/14. doi: 10.1007/978-1-0716-2111-0_8. PubMed PMID: 35554904.

Edwards MR, Vogel OA, Mori H, Davey RA, Basler CF. 2022. Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene. mBio doi:10.1128/mbio.02243-22:e0224322. PMID: 35997284.