The research conducted in the Krulwich laboratory focuses on areas of bioenergetics in several bacterial strains and settings. Projects include the following:
A Bioenergetic Conundrum: How do alkaliphilic bacteria, which thrive in highly alkaline environments, carry out oxidative phosphorylation that depends on a protonmotive force which is very low under these conditions?
Staphylococcus aureus is also adapted to growth at pH values of 9-9.5; what is the utility of this adaptation and what are the properties of the antiporters that support it?
Preiss et al. 2015. Front Bioeng. Biotech. 3:75 PMC4453477
Janto et al. 2011. Environ. Microbiol. 13:3289-3309 PMC3228905