The Krammer Laboratory

wf_fluvirus_all_usCross-reactive antibody responses towards viral surface glycoproteins: Translating basic research into novel vaccines and therapeutics

The Krammer laboratory studies cross-reactive antibody responses to the surface glycoproteins of antigenically variable RNA viruses. Our main focus is on influenza viruses, but we are also interested in antibody responses to hantaviruses, filoviruses, and other emerging RNA viruses. Work done in the laboratory includes the expression and characterization of viral glycoproteins, generation of glycoprotein-directed monoclonal antibodies, and the characterization of the interaction between antibodies and surface glycoproteins; we are specifically interested in analyzing conserved epitopes and – through detailed studies – aim to elucidate the mechanisms by which these antibodies protect the host from viral infection and disease. The final goal is to translate these findings into novel vaccines and therapeutics.

Contact:

Florian Krammer, PhD
Associate Professor
Department of Microbiology
Icahn School of Medicine at Mount Sinai
One Gustave L. Levy Place, Box 1124
New York, NY 10029
Tel: 212-241-8166
Fax: 212-534-1684
florian.krammer@mssm.edu

Krammer laboratory members will also be present at the following 2018 conferences – reach out to us if you have any questions:

 

U.S.-Japan Cooperative Medical Sciences Program (USJCMSP) 20th International Conference On Emerging Infectious Diseases In The Pacific Rim – Shenzhen, China, January 2018

18th International Congress on Infectious Diseases – Buenos Aires, Argentina, March 2018

4th International Symposium on Neglected Influenza Viruses – Brighton, UK, April 2018

Medical Biotechnology – Gent, Belgium, May 2018

ASM Microbe 2018 – Atlanta, USA, June 2018

Vaccine Technology VII – Mont Tremblant, Canada, June 2018

ASV Meeting – College Park, USA, July 2018

CEIRS Meeting (closed) – New York, USA, 2018