11\/05\/2026, Coming up: the lab will present three posters at AASLD The Liver Meeting 2026 in Denver, CO. \u2018Baseline oral microbiome composition and vitamin K biosynthesis capacity distinguish patients with liver stiffness progression in a diverse urban MASLD population\u2019 and \u2018Real-world liver stiffness trajectories identify glycemic control as an important predictor of rapid fibrosis progression in a diverse urban MASLD population\u2019 (first author Adeeba Tak), and \u2018Ethnicity modifies the association of diet and insurance with liver stiffness in a diverse urban MASLD population\u2019 (first author Maryfe Coronel).<\/p>\n
8\/14\/2026 NIH R01 Awarded.<\/strong> We are excited to share that the lab has received an NIH\/NIDDK R01 to test a simple question: can navy beans, worked into everyday eating, change the course of liver disease? The randomized crossover trial will enroll adults with MASLD and combine liver imaging with microbiome and multi-omics analyses to understand how dietary fiber and food matrix shape the gut\u2013liver axis. Learn more Bean-MASLD trial on ClinicalTrials.gov<\/a>.<\/p>\n 8\/12\/2026, Congratulations! Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on \u2018Comparative risk of hepatocellular carcinoma and mortality among initiators of GLP-1 receptor agonists versus other glucose-lowering therapies: a target trial emulation\u2019 has been published in Hepatology International <\/em><\/strong><\/span>.\u00a0Here is the study detail.\u00a0<\/a><\/p>\n 7\/13\/2026, Congratulations! Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on \u2018Oncogenic Ras drives EED degradation and PRC2 dysfunction to promote aggressive squamous cell carcinoma\u2019 has been published in Nature Communications<\/em><\/strong><\/span>.\u00a0Here is the study detail.\u00a0<\/a><\/p>\n 07\/2026, A high school student from the Mount Sinai Center for Excellence in Youth Education (CEYE) joined the lab.<\/p>\n 6\/30\/2026, Congratulations! Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on \u2018Sexual dimorphism in the association of circulating TAM receptors\u2013ligands with MASLD-related fibrosis\u2019 has been published in JHEP Reports<\/em><\/strong><\/span>.\u00a0Here is the study detail.\u00a0<\/a><\/p>\n 06\/2026, Welcome Renyun Huang to join our lab as a research intern.<\/p>\n 05\/27\/2026, The lab presented two abstracts at the EASL Congress 2026 in Barcelona: \u2018Utility of ELF compared with VCTE in guideline-based fibrosis assessment pathways using MRE as reference\u2019 and \u2018Barriers to Second-Line Therapy in Primary Biliary Cholangitis after Ursodeoxycholic Acid Failure\u2019.<\/p>\n 05\/02\/2026, The lab presented \u2018Acculturation and liver health inequities: national patterns in steatosis and fibrosis severity\u2019 at Digestive Disease Week 2026 in Chicago.<\/p>\n 04\/2026, Welcome Siyang Shen to join our lab as a research intern.<\/p>\n 3\/15\/2026, Congratulations! Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on \u2018High dietary fiber is associated with improved outcomes in patients with melanoma and sarcoma treated with immunotherapy regardless of gut microbiome dysbiosis and social vulnerability\u2019 has been published in Cancer<\/em><\/strong><\/span>.\u00a0Here is the study detail.\u00a0<\/a><\/p>\n 3\/10\/2026, Congratulations! Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on \u2018Analysis of a PCORnet\u00ae database identifies multi-level predictors of delta hepatitis in a U.S. hotspot\u2019 has been published in Communications Medicine<\/em><\/strong><\/span>.\u00a0Here is the study detail.\u00a0<\/a><\/p>\n 2026, Dr. Xiaotao Zhang<\/strong> started a new graduate course, Nutritional Epidemiology, at the Graduate School of Biomedical Sciences and serves as its course director.<\/p>\n 2026, Dr. Xiaotao Zhang<\/strong> served on the USDA NIFA FASLP grant review panel.<\/p>\n 12\/22\/2025, Congratulations! Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on \u2018Investigating Chronic Toxicity, Diet, Patient-Reported Outcomes and the Microbiome in Immunotherapy-Treated Metastatic Melanoma Survivors: A New Frontier\u2019 has been published in Nutrients<\/em><\/strong>\u00a0<\/span>.\u00a0Here is the study detail.\u00a0<\/a><\/p>\n 12\/2025, Welcome Adeeba Tak to join our lab as a research intern.<\/p>\n 11\/07\/2025, The lab presented \u2018Prospective Cohort Study Identifies Dietary and Oral Microbial Signatures Associated with significant MASLD fibrosis\u2019 at AASLD The Liver Meeting 2025 in Washington, DC.<\/p>\n 11\/2025, Mount Sinai Reports featured our medically tailored meals trial in MASH and interviewed Dr. Xiaotao Zhang<\/strong> about the study. Read the article.<\/a><\/p>\n 11\/04\/2025, Congratulations! Our trainee Lulu He and Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on \u2018Dietary Interventions in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Narrative Review of Evidence, Mechanisms, and Translational Challenges\u2019 has been published in Nutrients<\/em><\/strong>\u00a0<\/span>.\u00a0Here is the study detail.<\/a>\u00a0 \u00a0 We also created a video abstract for it. From Plate to Liver: How Diet Shapes MASLD<\/a><\/p>\n 10\/2025, Dr. Xiaotao Zhang<\/strong> gave an invited talk, \u2018The Human Microbiome and Cancer: Relevance for Early Lung Cancer\u2019, at the 48th International Conference on Screening for Lung Cancer in New York.<\/p>\n 09\/03\/2025, Congratulations! Our trainee Ruiqi Tang and Dr. Xiaotao Zhang<\/strong>\u2018s recent article on \u2018Nordic Nutrition Recommendations 2023 Food-Based Diet Score and Mortality: Advancing Evidence for Sustainable, Food-Based Dietary Guidance\u2019 has been published in The Journal of Nutrition<\/em><\/strong>. Here is the study detail.<\/a><\/p>\n 07\/31\/2025, Congratulations! Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on \u2018Novel Implementation of Hepatitis B to Hepatitis Delta Reflex Testing in a United States Healthcare System<\/span>\u2019 has been published in American Journal of Gastroenterology<\/em><\/strong>\u00a0<\/span>.\u00a0Here is the study detail.\u00a0<\/a><\/p>\n 07\/21\/2025, Welcome Ruoyan Pan<\/strong>\u00a0to join our lab as a Research Assistant.<\/p>\n 07\/10\/2025, Congratulations! Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on ‘Real-world Comparison of SAFE and FIB-4 Scores for Assessing MASLD-Related Fibrosis in a highly diverse urban MASLD population\u2019 has been published in\u00a0Clinical Gastroenterology and Hepatology<\/strong><\/em>. Here is the study detail.\u00a0<\/a><\/p>\n 06\/19\/2025,\u00a0 Congratulations!\u00a0Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on ‘Identifying Environmental Factors Associated with Significant Fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease\/Steatohepatitis’ has been published in Digestive Diseases and Sciences<\/strong><\/em>. Here is the study detail.\u00a0<\/a><\/p>\n 06\/17\/2025, Welcome Ruiqi Tang<\/strong> to join our lab as a Research Assistant.<\/p>\n 06\/16\/2025, Congratulations! Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on ‘Translating HDV Screening Cost-Effectiveness into Practice: the Case for Reflex Testing in the United States’ has been published in Clinical Infectious Diseases<\/strong><\/em>. Here is the study detail.\u00a0<\/a><\/p>\n 06\/05\/2025, Welcome Yunxi Pu<\/strong>\u00a0to join our lab as a Research Analyst Intern.<\/p>\n 05\/23\/2025, Congratulations!\u00a0Dr. Xiaotao Zhang<\/strong>\u2018s recent research paper on ‘Bias in the Bowels: Disparities Exist in Constipation Testing in a Diverse Patient Cohort’ has been published in Clinical Gastroenterology and Hepatology<\/strong><\/em>. Here is the study detail.\u00a0<\/a><\/p>\n 2025, Dr. Xiaotao Zhang<\/strong> received the Springer Nature Author Service Award and the Springer Nature Editorial Contribution Award, and was named a Top Peer Reviewer by JAMA Oncology<\/em><\/strong> for 2024 and 2025.<\/p>\n 09\/06\/2024, Congratulations! Dr. Xiaotao Zhang<\/strong> has completed the 12-month Leadership Emerging in Academic Departments (LEAD) Program.<\/p>\n 09\/05\/2024, Welcome Maryfe Coronel<\/strong> to join our lab as a rotation student<\/p>\n 08\/30\/2024, Congratulations!\u00a0 Our lab research intern Yuqing’s <\/strong>recent paper on ‘Dietary Micronutrients Intake and Alcoholic Liver Disease: A UK Biobank Study’ has been published in\u00a0The Journal of Nutrition<\/em><\/strong>.\u00a0Here is the study details<\/a>.<\/p>\n 08\/29\/2024, Congratulations!\u00a0Dr. Xiaotao Zhang<\/strong>‘s recent article on ‘Adverse pregnancy outcomes and effect of treatment in Wilson disease during pregnancy: Systematic review and meta-analysis’ has been published in\u00a0Liver international<\/strong>,\u00a0<\/em>here is the study details.\u00a0<\/a><\/p>\n 08\/28\/2024, Congratulations! Dr. Xiaotao Zhang<\/strong>‘s recent orignial research article on ‘Food insecurity trends and disparities according to immigration status in the US households, 2011\u20132021’ has been published in Preventive Medicine<\/strong>, <\/em>here is the study details.\u00a0<\/a><\/p>\n 07\/22\/2024, Welcome Jiangyuan Zhu<\/strong> to join our lab as a research intern.<\/p>\n 07\/08\/2024, Welcome Yuqing Liu<\/strong>\u00a0to join our lab as a research intern.<\/p>\n 04\/15\/2024, Congratulations!\u00a0 Our lab research intern Christie Lee Luo<\/strong> recent paper on ‘Psychological comorbidities are more prevalent amongst pregnant and postpartum patients with irritable bowel syndrome’ has been published in Neurogastroenterology and motility<\/em><\/strong>. Here is the study details.\u00a0<\/a><\/p>\n 03\/15\/2024, Dr. Xiaotao Zhang gave a talk on Division of Occupational Medicine grand rounds on biological and modifiable factors in both liver diseases and cancer prevention. Here is the video recording<\/a>.<\/p>\n 03\/12\/2024, Congratulations! Dr. Xiaotao Zhang<\/strong>‘s recent review on ‘One-Carbon Metabolism Nutrients, Genetic Variation, and Diabetes Mellitus’ has been published in Diabetes & Metabolism Journal<\/strong>, <\/em>here is the study details.\u00a0<\/a><\/p>\n 02\/02\/2024, Congratulations! Dr. Xiaotao Zhang<\/strong>‘s recent comment on 2018 WCRF\/AICR recommendations on lifestyle related cancers has been published in BMC Global and Public Health<\/em><\/strong>, here is the study details.<\/a><\/p>\n 12\/18\/2023, Congratulations on the Upcoming Institute for Translational Epidemiology short courses <\/strong>taught by our lab: 1) 01\/24\/2024: Introduction to Meta-Analysis Workshop,\u00a0 2) March\/April, 2024: Epidemiology Methods, Go to www.sinai-ite.com<\/a> for more info!<\/p>\n 12\/13\/2023, Welcome\u00a0Kamileh Rivera<\/strong>\u00a0to join our lab as a research intern.<\/p>\n 12\/8\/2023, Congratulations! At the New York Academy of Medicine, the Institute for Translational Epidemiology<\/strong> retreat<\/strong> for collaborations and connections was hosted.<\/p>\n 11\/30\/2023, Congratulations!\u00a0Dr. Xiaotao Zhang’s<\/strong>\u00a0recent study has underscored the prebiotic and potential therapeutic role of beans in enhancing the gut microbiome and regulating host markers associated with metabolic obesity and colorectal cancer,\u00a0here is the study details<\/a><\/p>\n 11\/20\/2023, Welcome Alexia Ma<\/strong>\u00a0to join our lab as a research intern.<\/p>\n 10\/9\/2023, Congratulations! Dr. Xiaotao Zhang’s<\/strong> recent study has identified\u00a0 1 plant-based pattern vs\u00a0 1 distinct fast-food\/meat-based pattern associated with detrimental effects among MASLD population using cluster analysis, here is the study details<\/a><\/span><\/p>\n <\/p>\n <\/p>\n","protected":false},"excerpt":{"rendered":" 11\/05\/2026, Coming up: the lab will present three posters at AASLD The Liver Meeting 2026 in Denver, CO. \u2018Baseline oral microbiome composition and vitamin K biosynthesis capacity distinguish patients with liver stiffness progression in a diverse urban MASLD population\u2019 and \u2018Real-world liver stiffness trajectories identify glycemic control as an important predictor of rapid fibrosis progression […]<\/p>\n","protected":false},"author":606,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"full-width.php","meta":{"footnotes":""},"class_list":["post-37","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/xiaotaozhanglab\/wp-json\/wp\/v2\/pages\/37","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/xiaotaozhanglab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/xiaotaozhanglab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/xiaotaozhanglab\/wp-json\/wp\/v2\/users\/606"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/xiaotaozhanglab\/wp-json\/wp\/v2\/comments?post=37"}],"version-history":[{"count":33,"href":"https:\/\/labs.icahn.mssm.edu\/xiaotaozhanglab\/wp-json\/wp\/v2\/pages\/37\/revisions"}],"predecessor-version":[{"id":605,"href":"https:\/\/labs.icahn.mssm.edu\/xiaotaozhanglab\/wp-json\/wp\/v2\/pages\/37\/revisions\/605"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/xiaotaozhanglab\/wp-json\/wp\/v2\/media?parent=37"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}