[et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|off|off” admin_label=”Header Title Description – Section – Header – Fullwidth Slider ” module_id=”header-title-description-slider-section1″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”#0e1228″ background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2024\/05\/TitlePic-1.png” background_size=”contain” background_position=”center_right” custom_padding=”||||false|false” top_divider_height=”10%” bottom_divider_height=”10%” locked=”on” collapsed=”on”][et_pb_fullwidth_slider show_arrows=”off” arrows_custom_color=”#D80B8C” dot_nav_custom_color=”#D80B8C” admin_label=”Fullwidth Slider” _builder_version=”4.9.0″ _module_preset=”default” header_text_align=”center” custom_margin=”|||0px|false|false” custom_padding=”|||0px|false|false”][et_pb_slide heading=”Welcome to the Wengler Lab” _builder_version=”4.9.0″ _module_preset=”default” header_text_align=”left” header_font_size=”60px” header_line_height=”60px” body_text_align=”left” body_font_size=”36px” body_line_height=”1.5em” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2024\/05\/TitlePic-5.png” background_enable_image=”on” text_orientation=”center” custom_padding=”||||false|false” sticky_transition=”on”]<\/p>\n
for Translational and Integrative Neuroimaging<\/p>\n
[\/et_pb_slide][\/et_pb_fullwidth_slider][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|on|on” admin_label=”Fullwidth Header – Background Title – no slider – Section 1 (mobile only)” module_class=”section1_fullwidth_header_bg_title_no_slider-team” _builder_version=”4.9.0″ _module_preset=”default” background_color=”#0e1228″ use_background_color_gradient=”on” background_color_gradient_start=”#141414″ background_color_gradient_end=”rgba(20,20,20,0.15)” background_color_gradient_direction=”1deg” background_color_gradient_end_position=”70%” background_color_gradient_overlays_image=”on” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2024\/05\/TitlePic-6.png” background_size=”contain” background_position=”center_right” custom_padding=”||||false|false” top_divider_style=”slant2″ top_divider_color=”#D80B8C” top_divider_height=”10%” top_divider_flip=”horizontal” bottom_divider_style=”slant2″ bottom_divider_color=”#00AEEF” bottom_divider_height=”10%” bottom_divider_arrangement=”above_content” locked=”on” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” border_color_all=”RGBA(0,0,0,0)” locked=”off” collapsed=”off”][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default” custom_padding=”10%||8vw||false|false” custom_padding_tablet=”0vw||0vw||true|false” custom_padding_phone=”” custom_padding_last_edited=”on|tablet”][et_pb_text admin_label=”Text – Title” _builder_version=”4.9.0″ _module_preset=”b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa” text_text_color=”#FFFFFF” header_font=”||||||||” header_text_align=”center” header_text_color=”#FFFFFF” header_font_size=”60px” header_line_height=”1.5em” header_2_text_color=”#FFFFFF” header_2_line_height=”1.5em” custom_margin=”10%|40%|||false|false” custom_padding=”||||false|false” header_font_size_tablet=”40px” header_font_size_phone=”24px” header_font_size_last_edited=”on|desktop”]<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|tablet” disabled_on=”on|on|on” admin_label=”Fullwidth Two Column Header and Image (no slider) – Section 1 (Desktop only)” module_class=”section1_header_no_slider” _builder_version=”4.9.0″ _module_preset=”default” background_color=”#00aeef” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/10\/Background-2.png” parallax=”on” custom_margin=”||30px||false|false” custom_padding=”||||false|false” custom_padding_tablet=”0px||0px||false|false” custom_padding_phone=”” bottom_divider_style=”slant” bottom_divider_color=”#FFFFFF” bottom_divider_arrangement=”above_content” custom_css_main_element=”padding: 0px !important;” disabled=”on” locked=”on” collapsed=”on”][et_pb_row column_structure=”2_5,3_5″ disabled_on=”off|off|off” _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” module_alignment=”right” custom_padding=”||||false|false” border_color_all=”RGBA(0,0,0,0)” collapsed=”on”][et_pb_column type=”2_5″ _builder_version=”4.9.0″ _module_preset=”default” custom_padding=”10%||8vw||false|false” custom_padding_tablet=”0vw||0vw||true|false” custom_padding_phone=”” custom_padding_last_edited=”on|desktop”][et_pb_text admin_label=”Title – Text” _builder_version=”4.9.0″ _module_preset=”da86b6f0-f83c-4c7c-bdd8-3019777ddffe” text_font=”||||||||” text_text_color=”#FFFFFF” text_font_size=”20px” text_line_height=”32px” header_text_align=”left” header_text_color=”#FFFFFF” header_font_size=”48px” header_line_height=”60px” custom_margin=”||2%||false|false” text_font_size_tablet=”15px” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” header_font_size_tablet=”40px” header_font_size_phone=”24px” header_font_size_last_edited=”on|phone” custom_css_main_element=”\/*margin-right: 8vw!important;*\/”]<\/p>\n
[\/et_pb_text][et_pb_text admin_label=”Description – Text” _builder_version=”4.9.0″ _module_preset=”da86b6f0-f83c-4c7c-bdd8-3019777ddffe” text_font=”||||||||” text_text_color=”#FFFFFF” text_font_size=”20px” text_line_height=”32px” header_text_align=”left” custom_margin=”||||false|false” text_font_size_tablet=”15px” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” custom_css_main_element=”\/*margin-right: 9vw!important;*\/”]<\/p>\n
Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”3_5″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”RGBA(0,0,0,0)”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2022\/07\/210629-Nivi-graduation-scaled.jpg” align=”right” force_fullwidth=”on” _builder_version=”4.9.0″ _module_preset=”default” custom_margin=”80px|0px|0px|0px|false|false” custom_padding=”20px|0px|0px|0px|false|false” box_shadow_style=”preset1″ box_shadow_spread=”15px”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ disabled_on=”on|on|on” _builder_version=”4.9.0″ _module_preset=”default” disabled=”on” collapsed=”on”][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_blurb title=”Welcome to the Rendl Lab” admin_label=”Blurb – Left Side Content” _builder_version=”4.9.0″ _module_preset=”default” header_text_color=”#FFFFFF” body_text_color=”#FFFFFF” custom_margin=”80px||||false|false”]<\/p>\n
Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n
[\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_blurb image=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2022\/07\/210629-Nivi-graduation-scaled.jpg” icon_alignment=”right” admin_label=”Blurb – Right-Side Image” _builder_version=”4.9.0″ _module_preset=”default” custom_margin=”80px|-40%|0px||false|false” custom_margin_tablet=”|0%|||false|false” custom_margin_phone=”|0%|||false|false” custom_margin_last_edited=”on|phone”][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Header and Image (no slider) – Section 1 (Tablet and Mobile only)” module_class=”section1_header_no_slider_mobile” _builder_version=”4.9.0″ background_color=”#00AEEF” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/10\/Background-2.png” parallax=”on” width=”100%” custom_margin=”||30px||false|false” custom_padding=”80px|0px|63px|0px||” mix_blend_mode=”multiply” bottom_divider_color=”#FFFFFF” bottom_divider_height=”150px” bottom_divider_flip=”horizontal” disabled=”on” locked=”on” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”|||” custom_padding=”|||”][et_pb_column type=”1_2″ _builder_version=”3.25″ background_position=”top_left” custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” header_text_color=”#FFFFFF” header_line_height=”1.7em”]<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_text_color=”#FFFFFF”]<\/p>\n
Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”3.25″ background_position=”top_left” custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2022\/07\/210629-Nivi-graduation-scaled.jpg” title_text=”AdobeStock_436735485″ disabled_on=”off|off|off” _builder_version=”4.9.0″ animation_style=”slide” animation_direction=”left” animation_intensity_slide=”10%” box_shadow_style=”preset1″ box_shadow_blur=”30px” box_shadow_color=”#58595B” always_center_on_mobile=”off”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Two Column Image and Text over Button – Section 6 (Collections)” module_class=”section6_two_col_img_txt_over_btn” _builder_version=”4.9.0″ background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/12\/9-alt.png” background_size=”initial” background_position=”top_right” background_repeat=”repeat-y” custom_margin=”30px||100px||false|false” custom_margin_tablet=”100px||||false|false” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” custom_padding=”0px|0px|0px|0px|false|false” custom_css_main_element=”padding: 0px !important;” locked=”on” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.9.0″ module_alignment=”center” custom_margin=”|auto|0px|auto||” custom_padding=”0px||0px|||” box_shadow_style=”preset1″ box_shadow_color=”#58595B” collapsed=”off”][et_pb_column type=”1_2″ _builder_version=”4.9.0″ background_color_gradient_direction=”35deg” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/08\/Rectangle-3-copy-5.jpg” custom_padding=”|5%||5%” custom_padding__hover=”|||”][et_pb_team_member image_url=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2024\/05\/10-30-23_columbia-psychiatry_horga-lab-1886_Cropped-scaled.jpg” _builder_version=”4.9.0″ _module_preset=”default” header_level=”h2″ header_text_color=”#FFFFFF” body_text_color=”#FFFFFF” body_line_height=”1em” positioning=”relative” vertical_offset=”20px” background_layout=”dark” animation_style=”zoom”][\/et_pb_team_member][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_text_color=”#FFFFFF” text_line_height=”1em” header_text_color=”#FFFFFF” header_2_text_color=”#FFFFFF” positioning=”relative” vertical_offset=”0px” horizontal_offset=”0px” z_index=”0″ custom_padding=”0px||10px||false|false”]<\/p>\n
Principal Investigator<\/strong><\/p>\n Assistant Professor<\/p>\n Department of Psychiatry<\/p>\n Department of Diagnostic, Molecular, and Interventional Radiology<\/p>\n BioMedical Engineering and Imaging Institute (BMEII)<\/p>\n Friedman Brain Institute<\/p>\n Icahn School of Medicine at Mount Sinai<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ background_color=”#FFFFFF” background_enable_image=”off” background_size=”contain” background_position=”top_left” background_repeat=”repeat” custom_padding=”40px|40px|40px|40px|true|true” custom_padding__hover=”|||”][et_pb_text disabled_on=”off|off|off” _builder_version=”4.9.0″ header_font=”|700|||||||” header_text_color=”#141414″ header_font_size=”36px” header_3_font=”|700|||||||” header_3_text_color=”#2b2b2b” header_3_font_size=”28px” header_3_line_height=”1.5em” custom_margin=”||10px|” custom_padding=”5%||||false|false”]<\/p>\n [\/et_pb_text][et_pb_text disabled_on=”on|off|off” admin_label=”Text (no mobile)” _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#000000″ text_font_size=”22px” text_line_height=”2em” header_font=”||||” header_text_color=”#000000″ header_4_text_color=”#FFFFFF” header_5_text_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”800px” custom_padding=”2%||5%||false|false” animation_style=”slide” animation_direction=”top” animation_intensity_slide=”4%”]<\/p>\n The Wengler Lab applies advanced computational neuroscience approaches and novel magnetic resonance imaging (MRI) methods to study the biological mechanisms of schizophrenia and other neuropsychiatric disorders. Additional focuses of the Wengler Lab are the development of MRI biomarkers for diagnosis and predicting treatment response using machine learning, and the use of integrative neuroscience approaches to investigate the genetic underpinnings of altered neural phenotypes in neuropsychiatric disorders.<\/p>\n [\/et_pb_text][et_pb_text disabled_on=”off|on|on” admin_label=”Text (mobile only)” _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#000000″ text_font_size=”15px” text_line_height=”1.5em” header_font=”||||” header_text_color=”#000000″ header_4_text_color=”#FFFFFF” header_5_text_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”800px” custom_padding=”2%||5%||false|false” animation_style=”slide” animation_direction=”top” animation_intensity_slide=”4%”]<\/p>\n The Wengler Lab applies advanced computational neuroscience approaches and novel magnetic resonance imaging (MRI) methods to study the biological mechanisms of schizophrenia and other neuropsychiatric disorders. Additional focuses of the Wengler Lab are the development of MRI biomarkers for diagnosis and predicting treatment response using machine learning, and the use of integrative neuroscience approaches to investigate the genetic underpinnings of altered neural phenotypes in neuropsychiatric disorders.<\/p>\n [\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/research\/” button_text=”Find Out More” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#FFFFFF” button_bg_color=”#00AEEF” button_border_radius=”0px” box_shadow_style=”preset1″ locked=”off”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Two Column Image and Text over Button – Section 4″ module_class=”section4_two_col_img_txt_over_btn” _builder_version=”3.22″ background_color=”#00AEEF” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/12\/Background-1ALT.png” parallax=”on” width=”100%” custom_margin=”30px||||false|false” custom_padding=”80px|0px|63px|0px||” mix_blend_mode=”multiply” bottom_divider_style=”ramp2″ bottom_divider_color=”#FFFFFF” bottom_divider_height=”150px” bottom_divider_flip=”horizontal” bottom_divider_arrangement=”above_content” disabled=”on” locked=”off” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”|||” custom_padding=”|||”][et_pb_column type=”1_2″ _builder_version=”3.25″ background_position=”top_left” custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2022\/08\/Stalled-follicles_03MR-2560×1440-1.jpg” title_text=”AdobeStock_436735485″ disabled_on=”off|off|off” _builder_version=”4.9.0″ animation_style=”slide” animation_direction=”left” animation_intensity_slide=”10%” box_shadow_style=”preset1″ box_shadow_color=”#58595B” always_center_on_mobile=”off”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”3.25″ background_position=”top_left” custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”22px” header_font=”||||” header_text_color=”#FFFFFF” header_4_text_color=”#FFFFFF” header_5_text_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”700px” animation_style=”slide” animation_direction=”top” animation_intensity_slide=”4%”]<\/p>\n Stem cells and their immediate environment, also called stem cell niche, are critical for the growth and continuous renewal of our organs, and are also key for new growth and repair during regeneration. Unlocking the secrets of how specialized niche cells operate to activate stem cells and progenitors holds great promise for regenerative medicine.<\/p>\n Our laboratory aims to answer these fundamental questions in stem cell biology by utilizing the hair follicle mini-organ as a powerful model system. Deciphering how niche cells govern stem cell and progenitor functions in the hair follicle will also provide a rational basis for developing hair regenerative therapies. Fundamental questions towards this goal are:<\/p>\n [\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Find Out More ” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#d80b8c” button_bg_color=”#FFFFFF” button_border_radius=”0px” box_shadow_style=”preset1″][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|on|on” admin_label=”Paralax Background fullwidth Image – Section 3″ module_class=”section3_paralax_bg_fullwidth_img” _builder_version=”4.9.0″ _module_preset=”default” disabled=”on” locked=”off” collapsed=”on”][et_pb_fullwidth_image title_text=”3″ _builder_version=”4.9.0″ _module_preset=”default” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/10\/3.png” parallax=”on” parallax_method=”off” min_height=”217.5px” custom_margin=”-2px|||||” filter_opacity=”20%”][\/et_pb_fullwidth_image][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Two Column Title Over Text Next to Image – Section 5″ module_class=”section5_two_col_title_over_txt_next_to_img” _builder_version=”4.9.0″ _module_preset=”default” disabled=”on” locked=”off” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” admin_label=”5 (Module)” _builder_version=”4.9.0″ background_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” custom_padding=”6px||3px|||” global_module=”956″][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_text_color=”#00AEEF” header_font=”|700|||||||” header_text_color=”#00AEEF” header_font_size=”36px” module_alignment=”center” custom_padding=”10%||10%||true|false”]<\/p>\n How is tissue growth, homeostasis and renewal by stem cells regulated throughout life? Understanding the core molecular controls is fundamental for realizing the therapeutic potential of the instructive niche (Rezza et al, Current Topics in Developmental Biology 2014). After initial morphogenesis of hair follicles, the Dermal Condensate gives rise to the adult follicle inductive niche, the Dermal Papilla. Dermal Papilla cells signal to progenitors in the follicle bulb to control continuous production and outgrowth of hair. They are also critical for activating stem cells to regenerate a new follicle during the hair growth cycle. Remarkably, isolated niche cells can induce new hair formation after cell transplantation into skin in mice, a yet unrealized goal in human.<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/07\/ai-008.png” title_text=”ai-008″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”#FFFFFF”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Two Column Image with Title and Text Over Button – Section 4 (Desktop Only)” module_class=”section4_two_col_img_next_to_title_over_txt_over_btn_desktop” _builder_version=”4.9.0″ _module_preset=”default” background_color=”#00AEEF” use_background_color_gradient=”on” background_color_gradient_start=”#00aeef” background_color_gradient_end=”#d80b8c” background_color_gradient_direction=”33deg” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/10\/Background-2.png” parallax=”on” module_alignment=”center” height=”558px” custom_margin=”||200px||false|false” disabled=”on” locked=”off” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/08\/2021-Hero-Shot-2-smallest-scaled-3.png” title_text=”2021-Hero-Shot-2-smallest-scaled-3″ _builder_version=”4.9.0″ _module_preset=”default” width=”91%” max_width=”91%” min_height=”550px” height=”550px” max_height=”550px” custom_padding=”40px||||false|false”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.9.0″ _module_preset=”default”][et_pb_text _builder_version=”4.9.0″ _module_preset=”default” text_text_color=”#FFFFFF” header_text_align=”center” header_text_color=”#FFFFFF” text_orientation=”center” custom_padding=”||||false|false”]<\/p>\n How tissues regenerate from stem cells and how different organs balance cell loss with new growth is under intensive investigation in the regenerative biology field. In the natural hair growth cycle after years of continuous hair growth, follicles enter a wave of massive progenitor death along the hair axis that \u2013 as we are just beginning to unravel \u2013 is controlled by the niche microenvironment. During this follicle regression, the Dermal Papilla niche needs to relocate from the base of growing hair bulbs to the stem cell reservoir in the upper follicle for new growth activation.<\/p>\n [\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Find Out More” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#d80b8c” button_bg_color=”#FFFFFF” button_border_radius=”0px” box_shadow_style=”preset1″ locked=”off”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Two Column Image with Title and Text Over Button – Section 4 (Mobile and Tablet Only)” module_class=”section4_one_col_img_over_title_over_txt_over_btn_mobile_tablet” _builder_version=”4.9.0″ background_color=”#00AEEF” use_background_color_gradient=”on” background_color_gradient_start=”#00aeef” background_color_gradient_end=”#d80b8c” background_color_gradient_direction=”33deg” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/10\/Background-1.png” parallax=”on” width=”100%” custom_margin=”||100px||false|false” custom_padding=”80px|0px|63px|0px||” bottom_divider_color=”#FFFFFF” bottom_divider_height=”150px” bottom_divider_flip=”horizontal” bottom_divider_arrangement=”above_content” disabled=”on” locked=”off” collapsed=”on”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” custom_margin=”|||” custom_padding=”|||”][et_pb_column type=”1_2″ _builder_version=”3.25″ background_position=”top_left” custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/08\/2021-Hero-Shot-2-smallest-scaled-3.png” title_text=”2021-Hero-Shot-2-smallest-scaled-3″ disabled_on=”off|off|off” _builder_version=”4.9.0″ animation_style=”slide” animation_direction=”left” animation_intensity_slide=”10%” box_shadow_style=”preset1″ box_shadow_color=”#58595B” always_center_on_mobile=”off”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”3.25″ background_position=”top_left” custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”22px” header_font=”||||” header_text_color=”#FFFFFF” header_4_text_color=”#FFFFFF” header_5_text_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”700px” animation_style=”slide” animation_direction=”top” animation_intensity_slide=”4%”]<\/p>\n How tissues regenerate from stem cells and how different organs balance cell loss with new growth is under intensive investigation in the regenerative biology field. In the natural hair growth cycle after years of continuous hair growth, follicles enter a wave of massive progenitor death along the hair axis that \u2013 as we are just beginning to unravel \u2013 is controlled by the niche microenvironment. During this follicle regression, the Dermal Papilla niche needs to relocate from the base of growing hair bulbs to the stem cell reservoir in the upper follicle for new growth activation.<\/p>\n [\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/design\/option1-research” button_text=”Find Out More” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_color=”#d80b8c” button_bg_color=”#FFFFFF” button_border_radius=”0px” box_shadow_style=”preset1″ locked=”off”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Fullwidth Video over Background – Section 9″ module_class=”fullwidth-video-over-background-section-9″ _builder_version=”4.9.0″ _module_preset=”default” background_color=”#ededed” background_image=”https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-content\/uploads\/sites\/516\/2022\/10\/4.png” height_tablet=”” height_phone=”” height_last_edited=”on|desktop” 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[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" for Translational and Integrative NeuroimagingWelcome to the Wengler Lab for Translational and Integrative NeuroimagingWelcome to the Rendl LabOur current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.Welcome to the Rendl Lab Our current research focuses on birth of the hair follicle niche, growth control and […]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-1349","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-json\/wp\/v2\/pages\/1349","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-json\/wp\/v2\/comments?post=1349"}],"version-history":[{"count":38,"href":"https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-json\/wp\/v2\/pages\/1349\/revisions"}],"predecessor-version":[{"id":5086,"href":"https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-json\/wp\/v2\/pages\/1349\/revisions\/5086"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/wenglerlab\/wp-json\/wp\/v2\/media?parent=1349"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}About<\/strong><\/h1>\n
Formation and Function of Stem Cell Niches<\/strong><\/h4>\n
\n
Growth Control and Regeneration<\/strong><\/h1>\n
Tissue Regression and Reorganization<\/strong><\/h1>\n
Tissue Regression and Reorganization<\/strong><\/h1>\n
<\/strong>kenneth.wengler@mssm.edu<\/p>\n
<\/strong>Tel: 212-585-4659<\/p>\n
1399 Park Ave
New York, NY 10029<\/p>\n