\u201cThreshold of Cognitive Impairment after HIV Infection: Effect of Morphine\u201d<\/p>\n
Principal Investigator:\u00a0 David J. Volsky, Ph.D.<\/p>\n
Agency:\u00a0 National Institute of Drug Abuse, NIH<\/p>\n
Type:\u00a0 R01 DA 037611; Period:\u00a0 04\/01\/2014-03\/31\/2019<\/p>\n
The goal of this project is to study the role of morphine in HIV-mediated neuropathogenesis.<\/p>\n
<\/p>\n
<\/p>\n
\u201cCNS Reservoirs of HIV in a Mouse Model of HIV Infection and Cognitive Impairment: Eradication Strategies\u201d<\/p>\n
Principal Investigator:\u00a0 David J. Volsky, Ph.D.<\/p>\n
Agency:\u00a0 National Institute of Mental Health, NIH<\/p>\n
Type:\u00a0 R01 MH 104145-01; Period:\u00a0 07\/01\/2014\u201304\/30\/2019<\/p>\n
The major goal of this project is to study the nature of HIV reservoirs in the brain and evaluate strategies for their elimination in mice.<\/p>\n
<\/p>\n
<\/p>\n
\u201cIntranasal Insulin Therapy for HIV-Associated Neurocognitive Disorders\u201d<\/p>\n
Principal Investigators:\u00a0 McArthur & Haughey, MPI<\/p>\n
Principal Investigators:\u00a0 David J. Volsky and Barbara Slusher, Dual PI in Project 2<\/p>\n
Agency:\u00a0 National Institute of Mental Health, NIH<\/p>\n
Type:\u00a0 P01 MH 105280-01A1; Period:\u00a0 09\/01\/2015\u201305\/31\/2020<\/p>\n
The major goal of this project is to study mitigation of HIV-induced cognitive disease by intranasal insulin treatment in an animal model and in patients.<\/p>\n
<\/p>\n
<\/p>\n
\u201cToward Control of HIV Neuropathogenesis by Innate Immunity\u201d<\/p>\n
Principal Investigators:\u00a0 Mary Jane Potash & David J. Volsky<\/p>\n
Agency:\u00a0 National Institute of Neurological Disorders and Stroke\/NIH<\/p>\n
Type:\u00a0 1 R01 NS 094146-01A1; Period:\u00a0 04\/01\/2016\u201303\/31\/2021<\/p>\n
The goal of this project is to define the basis of protective innate immune responses of macrophages to HIV in mice to prevent HIV infection in the brain or its associated brain disease.<\/p>\n
<\/p>\n
<\/p>\n
\u201cEffect of Buprenorphine on Monocytes in the Context of NeuroAIDS and Opioid Abuse\u201d<\/p>\n
Principal Investigators:\u00a0 Joan Berman & David J. Volsky<\/p>\n
Agency: National Institute on Drug Abuse\/NIH<\/p>\n
Type:\u00a0 1 R01 DA 041931-01A1; Period:\u00a0 04\/15\/2017\u201306\/30\/2022<\/p>\n
The overall goal of this project is to investigate the potential dual mechanism of action of buprenorphine as an opiate antagonist and inhibitor of monocyte migration to the brain, thus establishing buprenorphine as a dual-action agent for treatment of both opiate abuse and cognitive disease in HIV-infected individuals.<\/p>\n","protected":false},"excerpt":{"rendered":"
\u201cThreshold of Cognitive Impairment after HIV Infection: Effect of Morphine\u201d Principal Investigator:\u00a0 David J. Volsky, Ph.D. Agency:\u00a0 National Institute of Drug Abuse, NIH Type:\u00a0 R01 DA 037611; Period:\u00a0 04\/01\/2014-03\/31\/2019 The goal of this project is to study the role of morphine in HIV-mediated neuropathogenesis. \u201cCNS Reservoirs of HIV in a Mouse Model of […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-27","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/volskylab\/wp-json\/wp\/v2\/pages\/27","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/volskylab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/volskylab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/volskylab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/volskylab\/wp-json\/wp\/v2\/comments?post=27"}],"version-history":[{"count":3,"href":"https:\/\/labs.icahn.mssm.edu\/volskylab\/wp-json\/wp\/v2\/pages\/27\/revisions"}],"predecessor-version":[{"id":44,"href":"https:\/\/labs.icahn.mssm.edu\/volskylab\/wp-json\/wp\/v2\/pages\/27\/revisions\/44"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/volskylab\/wp-json\/wp\/v2\/media?parent=27"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}