{"id":20,"date":"2023-03-30T15:04:30","date_gmt":"2023-03-30T15:04:30","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/?page_id=20"},"modified":"2026-06-18T14:12:56","modified_gmt":"2026-06-18T14:12:56","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Selected publications<\/strong><\/p>\n

Can Nuclear Imaging Detect Trained Immunity in Cardiovascular Disease?<\/strong><\/a> Teunissen AJP, van Leent MMT<\/strong>. Arterioscler Thromb Vasc Biol. 2025<\/p>\n

Uncovering atherosclerotic cardiovascular disease by PET imaging.<\/strong><\/a> Maier A, Teunissen AJP, Nauta SA, Lutgens E, Fayad ZA, van Leent MMT<\/strong>.\u00a0 Nat Rev Cardiol. 2024 Apr 4;1\u201320.<\/p>\n

Cortico-limbic interactions and carotid atherosclerotic burden during chronic stress exposure.<\/strong><\/a> Gharios C, van Leent MMT<\/strong>, Chang HL, Abohashem S, O\u2019Connor D, Osborne MT, et al. European Heart Journal. 2024 May 16;ehae149.<\/p>\n

Macrophage PET imaging in mouse models of cardiovascular disease and cancer with an apolipoprotein-inspired radiotracer.<\/strong><\/a> Toner YC, Pr\u00e9vot G, van Leent MMT<\/strong>, Munitz J, Oosterwijk R, Verschuur AVD, et al.npj Imaging. 2024 May 15;2(1):1\u201310.<\/p>\n

Multiparametric Immunoimaging Maps Inflammatory Signatures in Murine Myocardial Infarction Models.<\/strong><\/a> Maier A, Toner Y, Munitz J, Sullivan N, Sakurai K, Meerwaldt AE, Brechb\u00fchl EES, Pr\u00e9vot G, van Elsas Y, Maas RJF, Ranzenigo A, Soultanidis G, Rashidian M, P\u00e9rez-Medina C, Heo GS, Gropler RJ, Liu Y, Reiner T, Nahrendorf M, Swirski F, Strijkers G, Teunissen AJP, Calcagno C, Fayad ZA, Mulder WJM, van Leent MMT<\/strong>. J Am Coll Cardiol Basic Trans Science.\u00a02023;0(0).<\/p>\n

Regulating trained immunity with nanomedicine. <\/a>van Leent MMT<\/strong>, Priem B, Schrijver DP, de Dreu A, Hofstraat SRJ, Zwolsman R, Beldman TJ, Netea MG, Mulder WJM. Nat Rev Mater. 2022 Feb 7.<\/p>\n

Employing nanobodies for immune landscape profiling by PET imaging in mice.<\/strong> <\/a>Teunissen AJP, Abousaway OB, Munitz J, van Leent MMT<\/strong>, Toner YC, Priem B, Senders ML, P\u00e9rez-Medina C, Mulder WJM, Rashidian M. STAR Protoc. 2021;2(2).<\/p>\n

Prosaposin mediates inflammation in atherosclerosis.<\/strong><\/a> van Leent MMT<\/strong>, Beldman TJ, Toner YC, Lameijer MA, Rother N, Bekkering S, Teunissen AJP, Zhou X, van der Meel R, Malkus J, Nauta SA, Klein ED, Fay F, Sanchez-Gaytan BL, P\u00e9rez-Medina C, Kluza E, Ye YX, Wojtkiewicz G, Fisher EA, Swirksi FK, Nahrendorf M, Zhang B, Li Y, Zhang B, Joosten LAB, Pasterkamp G, Boltjes A, Fayad ZA, Lutgens E, Netea MG, Riksen N, Mulder WJM, Duivenvoorden R. Sci Transl Med. 2021 Mar 10;13(584):eabe1433.<\/p>\n

A modular approach toward producing nanotherapeutics targeting the innate immune system.<\/a> van Leent MMT<\/strong>, Meerwaldt AE, Berchouchi A, Toner YC, Burnett ME, Klein ED, Verschuur AVD, Nauta SA, Munitz J, Pr\u00e9vot G, van Leeuwen EM, Ordikhani F, Mourits VP, Calcagno C, Robson PM, Soultanidis G, Reiner T, Joosten RRM, Friedrich H, Madsen JC, Kluza E, van der Meel R, Joosten LAB, Netea MG, Ochando J, Fayad ZA, P\u00e9rez-Medina C, Mulder WJM, Teunissen AJP. Sci Adv. 2021 Mar 5;7(10):eabe7853.<\/p>\n

Immune Checkpoint Inhibitor Therapy Aggravates T Cell\u2013Driven Plaque Inflammation in Atherosclerosis.<\/strong><\/a> Poels K, van Leent MMT<\/strong>, Boutros C, Tissot H, Roy S, Meerwaldt AE, Toner YC, Reiche ME, Kusters PJH, Malinova T, Huveneers S, Kaufman AE, Mani V, Fayad ZA, de Winther MPJ, Marabelle A, Mulder WJM, Robert C, Seijkens TTP, Lutgens E. JACC CardioOncology. 2020 Nov;2(4):599\u2013610.<\/p>\n

Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition.<\/strong> <\/a>Priem B, van Leent MMT<\/strong>, Teunissen AJP, Sofias AM, Mourits VP, Willemsen L, Klein ED, Oosterwijk RS, Meerwaldt AE, Munitz J, Pr\u00e9vot G, Verschuur AV, Nauta SA, van Leeuwen EM, Fisher EL, de Jong KAM, Zhao Y, Toner YC, Soultanidis G, Calcagno C, Bomans PHH, Friedrich H, Sommerdijk N, Reiner T, Duivenvoorden R, Zupan\u010di\u010d E, Di Martino JS, Kluza E, Rashidian M, Ploegh HL, Dijkhuizen RM, Hak S, P\u00e9rez-Medina C, Bravo-Cordero JJ, de Winther MPJ, Joosten LAB, van Elsas A, Fayad ZA, Rialdi A, Torre D, Guccione E, Ochando J, Netea MG, Griffioen AW, Mulder WJM. Cell. 2020 Oct;183(3):786\u2013801.<\/p>\n","protected":false},"excerpt":{"rendered":"

Selected publications Can Nuclear Imaging Detect Trained Immunity in Cardiovascular Disease? Teunissen AJP, van Leent MMT. Arterioscler Thromb Vasc Biol. 2025 Uncovering atherosclerotic cardiovascular disease by PET imaging. Maier A, Teunissen AJP, Nauta SA, Lutgens E, Fayad ZA, van Leent MMT.\u00a0 Nat Rev Cardiol. 2024 Apr 4;1\u201320. Cortico-limbic interactions and carotid atherosclerotic burden during chronic […]<\/p>\n","protected":false},"author":605,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-20","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/wp-json\/wp\/v2\/pages\/20","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/wp-json\/wp\/v2\/users\/605"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/wp-json\/wp\/v2\/comments?post=20"}],"version-history":[{"count":6,"href":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/wp-json\/wp\/v2\/pages\/20\/revisions"}],"predecessor-version":[{"id":189,"href":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/wp-json\/wp\/v2\/pages\/20\/revisions\/189"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/vanleentlab\/wp-json\/wp\/v2\/media?parent=20"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}