Selected Publications from the Stahl Lab<\/p>\n
A near-complete list of Eli Stahl’s publications is available from my\u00a0Google Scholar<\/a>\u00a0page.<\/p>\n See the\u00a0Projects<\/a>\u00a0page for more information on our activities.<\/p>\n A polygenic burden of rare disruptive mutations in schizophrenia<\/b> Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases<\/b> Genome-wide association analysis identifies 13 new risk loci for schizophrenia<\/b> A Role for Noncoding Variation in Schizophrenia<\/b> Genetics of rheumatoid arthritis contributes to biology and drug discovery<\/b> Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance)<\/b> Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease<\/b> Biological insights from 108 schizophrenia-associated genetic loci\u00a0<\/b> Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene<\/b> Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance)<\/b> Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol<\/b> Estimation of SNP heritability from dense genotype data<\/b> Quantifying missing heritability at known GWAS loci<\/b> Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes.\u00a0<\/b> Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway.\u00a0<\/b> Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge.\u00a0<\/b> Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis<\/b> Rare, low-frequency, and common variants in the protein coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis<\/b> High density genetic mapping in rheumatoid arthritis identifies 14 new Caucasian susceptibility loci\u00a0<\/b> Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis\u00a0<\/b> Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12<\/b> Integrating autoimmune risk loci with gene expression data identifies specific pathogenic immune cell subsets<\/b> Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records<\/b> Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci<\/b> Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci<\/b> Stahl Lab Publications Selected Publications from the Stahl Lab A near-complete list of Eli Stahl’s publications is available from my\u00a0Google Scholar\u00a0page. Most relevant publications See the\u00a0Projects\u00a0page for more information on our activities. Bayesian inference analyses of the polygenic architecture of rheumatoid arthritisStahl EA, Wegmann D, Trynka G, Gutierrez-Achury J, Do R, Voight BF, Kraft P, […]<\/p>\n","protected":false},"author":146,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-26","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/stahllab\/wp-json\/wp\/v2\/pages\/26","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/stahllab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/stahllab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/stahllab\/wp-json\/wp\/v2\/users\/146"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/stahllab\/wp-json\/wp\/v2\/comments?post=26"}],"version-history":[{"count":3,"href":"https:\/\/labs.icahn.mssm.edu\/stahllab\/wp-json\/wp\/v2\/pages\/26\/revisions"}],"predecessor-version":[{"id":29,"href":"https:\/\/labs.icahn.mssm.edu\/stahllab\/wp-json\/wp\/v2\/pages\/26\/revisions\/29"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/stahllab\/wp-json\/wp\/v2\/media?parent=26"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Most relevant publications<\/h2>\n
\nPurcell SM, JL Moran, M Fromer, D Ruderfer, N Solovieff, P Roussos, C O\u2019Dushlaine, K Chambert, SE Bergen, A K\u00e4hler, L Duncan, E Stahl, G Genovese, E Fern\u00e1ndez, MO Collins, NH Komiyama, JS Choudhary, PK Magnusson, E Banks, K Shakir, K Garimella, T Fennell, M DePristo, SG Grant, SJ Haggarty, S Gabriel, EM Scolnick, ES Lander, C Hultman, P Sullivan, S McCarroll, P Sklar. (2014)
\nNature<\/em>\u00a0506<\/b>(7487): 185-90. doi:10.1038\/nature12975 [PubMed<\/a>]<\/p>\n<\/div>\n<\/div>\n
\nGusev, A, SH Lee, G Trynka, H Finucane, BJ Vilhj\u00e1lmsson, H Xu, C Zang, Stephan Ripke, Brendan Bulik-Sullivan, Eli Stahl, Anna K K\u00e4hler, Christina M Hultman, Shaun M Purcell, Steven A McCarroll, Mark Daly, Bogdan Pasaniuc, Patrick F Sullivan, Benjamin M Neale, Naomi R Wray, Soumya Raychaudhuri, Alkes L Price, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium. (2014)
\nThe American Journal of Human Genetics<\/em>\u00a095<\/b>(5): 535-552. doi: 10.1016\/j.ajhg.2014.10.004 [PubMed<\/a>]<\/p>\n<\/div>\n<\/div>\n
\nRipke, S, O’Dushlaine C, Chambert K, Moran JL, K\u00e4hler AK, Akterin S, Bergen SE, Collins AL, Crowley JJ, Fromer M, Kim Y, Lee SH, Magnusson PK, Sanchez N, Stahl EA, Williams S, Wray NR, …, O’Donovan MC, Stefansson K, Scolnick E, Purcell S, McCarroll SA, Sklar P, Hultman CM, Sullivan PF. (2013)
\nNature Genetics<\/em>\u00a045<\/b>(10), 1150-1159. doi: 10.1038\/ng.2742. Epub 2013 Aug 25 [PubMed<\/a>]<\/p>\n<\/div>\n<\/div>\n
\nRoussos, P, AC Mitchell, G Voloudakis, JF Fullard, VM Pothula, J Tsang, EA Stahl, A Georgakopoulos, DM Ruderfer, A Charney, Y Okada, KA Siminovitch, J Worthington, L Padyukov, L Klareskog, PK Gregersen, RM Plenge, S Raychaudhuri, M Fromer, SM Purcell, K Brennand, NK Robakis, EE Schadt, S Akbarian, P Sklar. (2014)
\nCell Reports<\/em>\u00a09<\/b>(4): 1417\u20131429. doi:10.1016\/ j.celrep.2014.10.015 [PubMed<\/a>]<\/p>\n<\/div>\n<\/div>\n
\nOkada, Y, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, A Suzuki, S Yoshida, RR Graham, A Manoharan, W Ortmann, T Bhangale, JC Denny, RJ Carroll, AE Eyler, JD Greenberg, JM Kremer, DA Pappas, L Jiang, J Yin, L Ye, D Su, J Yang, G Xie, E Keystone, H Westra, T Esko, A Metspalu, X Zhou, N Gupta, D Mirel, EA Stahl, …, S Bae, J Worthington, L Padyukov, L Klareskog, PK Gregersen, S Raychaudhuri, BE Stranger, PL De Jager, L Franke, PM Visscher, MA Brown, H Yamanaka, T Mimori, A Takahashi, H Xu, TW Behrens, KA Siminovitch, S Momohara, F Matsuda, K Yamamoto, RM Plenge. (2014)
\nNature<\/em>\u00a0506<\/b>: 376-381. doi:10.1038\/nature12873 [PubMed<\/a>]<\/p>\n<\/h4>\n<\/div>\n<\/div>\n
\nA Chhibber, J Mefford, EA Stahl, SA Pendergrass, RM Baldwin, K Owzar, M Li, EP Winer, CA Hudis, H Zembutsu, M Kubo, Y Nakamura, HL McLeod, MJ Ratain, LN Shulman, MD Ritchie, RM Plenge, JS Witte, DL Kroetz. (2014)
\nThe pharmacogenomics journal<\/em>\u00a014<\/b>(4), 336-342.<\/p>\n<\/div>\n<\/div>\n
\nJN Hutchinson, T Raj, J Fagerness, E Stahl, FT Viloria, A Gimelbrant, J Seddon, M Daly, A Chess, R Plenge. (2014)
\nPLoS One<\/em>\u00a09<\/b>(6), e98464.<\/p>\n<\/div>\n<\/div>\n
\nSchizophrenia Working Group of the Psychiatric Genomics Consortium. (2014)
\nNature<\/em>\u00a0511<\/b>(7510): 421-4277. doi: 10.1038\/nature13595<\/p>\n<\/div>\n<\/div>\n
\nOkada, Y, D Diogo, JD Greenberg, F Mouassess, WAL Achkar, RS Fulton, JC Denny, N Gupta, D Mirel, S Gabriel, G Li, JM Kremer, DA Pappas, RJ Carroll, AE Eyler, G Trynka, EA Stahl, …, PL De Jager, S Raychaudhuri, J Worthington, L Padyukov, L Klareskog, KA Siminovitch, PK Gregersen, ER Mardis, T Arayssi, LA Kazkaz and RM Plenge. (2014)
\nPLoS One<\/em>\u00a02014 Feb 10;9<\/b>(2):e87645. doi: 10.1371\/journal.pone.0087645<\/p>\n<\/div>\n<\/div>\nOther Relevant Publications<\/h2>\n
\nChhibber, A, J Mefford, EA Stahl, SA Pendergrass, RM Baldwin, K Owzar, M Li, EP Winer, CA Hudis, H Zembutsu, M Kubo, Y Nakamura, HL McLeod, MJ Ratain, LN Shulman, MD Ritchie, RM Plenge, JS Witte, and DL Kroetz. (2014)
\nPharmacogenomics J<\/em>\u00a014<\/b>(4):336-42. doi: 10.1038\/tpj.2014.2<\/p>\n<\/div>\n<\/div>\n
\nLange, LA, Y Hu, H Zhang, C Xue, EM Schmidt, Z Tang, C Bizon, EM Lange, JD Smith, EH Turner, G Jun, HM Kang, G Peloso, P Auer, K Li, J Flannick, J Zhang, C Fuchsberger, K Gaulton, C Lindgren, A Locke, A Manning, X Sim, MA Rivas, OL Holmen, O Gottesman, Y Lu, D Ruderfer, EA Stahl, …, KE North, AP Reiner, E Boerwinkle, BM Psaty, D Altshuler, S Kathiresan, D Lin, GP Jarvik, LA Cupples, C Kooperberg, JG Wilson, DA Nickerson, GR Abecasis, SS Rich, RP Tracy, CJ Willer. (2014)
\nAmerican Journal of Human Genetics<\/em>\u00a094<\/b>(2):233-45. doi: 10.1016\/j.ajhg.2014.01.010<\/p>\n<\/div>\n<\/div>\n
\nLee SH, J Yang, GB Chen, S Ripke, EA Stahl, CM Hultman, P Sklar, PM Visscher, PF Sullivan, ME Goddard, NR Wray. (2013)
\nAm J Hum Genet<\/em>\u00a093<\/b>:1151-5. doi: 10.1016\/j.ajhg.2013.10.015<\/p>\n<\/div>\n<\/div>\n
\nGusev, A, G Bhatia, N Zaitlen, BJ Vilhjalmsson, D Diogo, EA Stahl, PK Gregersen, J Worthington, L Klareskog, S Raychaudhuri, RM Plenge, B Pasaniuc, AL Price. (2014)
\nPLoS genetics<\/em>\u00a09<\/b>(12), e1003993. doi: 10.1371\/journal.pgen.1003993 [PubMed<\/a>]<\/p>\n<\/div>\n<\/div>\n
\nMcGeachie MJ, Stahl EA, Himes BE, Pendergrass SA, Lima JJ, Irvin CG, Peters SP, Ritchie MD, Plenge RM, Tantisira KG. (2013)
\nPharmacogenetic Genomics<\/em>\u00a023<\/b>(6): 324-328. doi: 10.1097\/FPC.0b013e3283607acf<\/p>\n<\/div>\n<\/div>\n
\nLi G, D Diogo, D Wu, J Spoonamore, V Dancik, L Franke, F Kurreeman, EJ Rossin, G Duclos, C Hartland, X Zhou, K Li, J Liu, PL De Jager, KA Siminovitch, A Zhernakova, S Raychaudhuri, J Bowes, S Eyre, L Padyukov, PK Gregersen, J Worthington; Rheumatoid Arthritis Consortium International (RACI), N Gupta, PA Clemons, E Stahl, N Tolliday, RM Plenge. (2013)
\nPLoS Genet<\/em>\u00a09<\/b>(5):e1003487. doi: 10.1371\/journal.pgen.1003487<\/p>\n<\/div>\n<\/div>\n
\nPlenge RM, Greenberg JD, Mangravite LM, Derry JM, Stahl EA, Coenen MJ, Barton A, Padyukov L, Klareskog L, Gregersen PK, Mariette X, Moreland LW, Bridges SL Jr, de Vries N, Huizinga TW, Guchelaar HJ; International Rheumatoid Arthritis Consortium (INTERACT), Friend SH, Stolovitzky G. (2013)
\nNat Genet<\/em>\u00a045<\/b>(5):468-9. doi: 10.1038\/ng.2623<\/p>\n<\/div>\n<\/div>\n
\nCui J*, EA Stahl*, S Saevarsdottir, C Miceli, D Diogo, G Trynka, T Raj, MU Mirkov, H Canhao, K Ikari, C Terao, Y Okada, S Wedr\u221a\u00a9n, J Askling, H Yamanaka, S Momohara, A Taniguchi, K Ohmura, F Matsuda, T Mimori, N Gupta, M Kuchroo, AW Morgan, JD Isaacs, AG Wilson, KL Hyrich, M Herenius, ME Doorenspleet, PP Tak, JB Crusius, IE van der Horst-Bruinsma, GJ Wolbink, PL van Riel, M van de Laar, HJ Guchelaar, NA Shadick, CF Allaart, TW Huizinga, RE Toes, RP Kimberly, SL Bridges Jr, LA Criswell, LW Moreland, JE Fonseca, N de Vries, BE Stranger, PL De Jager, S Raychaudhuri, ME Weinblatt, PK Gregersen, X Mariette, A Barton, L Padyukov, MJ Coenen, EW Karlson, RM Plenge. (2013)
\nPLoS Genetics<\/em>\u00a09<\/b>(3):e1003394. doi: 10.1371\/journal.pgen.1003394<\/p>\n<\/div>\n<\/div>\n
\nDiogo, D, F Kurreeman, EA Stahl, KP Liao, N Gupta, …, Consortium of Rheumatology Researchers of North America; Rheumatoid Arthritis Consortium International, Sunyaev S, Martin J, Zhernakova A, Bowes J, Eyre S, Siminovitch KA, Gregersen PK, Worthington J, Klareskog L, Padyukov L, Raychaudhuri S, Plenge RM. (2013)
\nAmerican Journal of Human Genetics<\/em>\u00a092<\/b>(1):15-27. doi: 10.1016\/j.ajhg.2012.11.012<\/p>\n<\/div>\n<\/div>\n
\nEyre, S, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, E Stahl, …, R Plenge, S Raychaudhuri, L Klareskog, PK Gregersen, J Worthington. (2012)
\nNature Genetics<\/em>\u00a044<\/b>(12):1336-40. doi: 10.1038\/ng.2462<\/p>\n<\/div>\n<\/div>\n
\nRaychaudhuri, S, C Sandor, EA Stahl, J Freudenberg, H-S Lee, X Jia, L Alfredsson, L Padyukov, L Klareskog, J Worthington, K Siminovitch, S-C Bae, RM Plenge, PK Gregersen, PIW de Bakker. (2012)
\nNature Genetics<\/em>\u00a044<\/b>(3):291-6. doi: 10.1038\/ng.1076<\/p>\n<\/div>\n<\/div>\n
\nKurreeman FA, Stahl EA, Okada Y, Liao K, Diogo D, Raychaudhuri S, Freudenberg J, Kochi Y, Patsopoulos NA, Gupta N, CLEAR investigators, Sandor C, Bang SY, Lee HS, Padyukov L, Suzuki A, Siminovitch K, Worthington J, Gregersen PK, Hughes LB, Reynolds RJ, Bridges SL Jr, Bae SC, Yamamoto K, Plenge RM (2012)
\nAm J Hum Genet<\/em>\u00a090<\/b>(3):524-32. doi: 10.1016\/j.ajhg.2012.01.010<\/p>\n<\/div>\n<\/div>\n
\nHu, X, H Kim, EA Stahl, RM Plenge, M Daly, S Raychaudhuri. (2011)
\nAm J Hum Genet<\/em>\u00a089<\/b>: 496-506. doi: 10.1016\/j.ajhg.2011.09.002<\/p>\n<\/div>\n<\/div>\n
\nKurreeman, F, K Liao, L Chibnik, B Hickey, EA Stahl, …, P Szolovits, S Churchill, SN Murphy, T Cai, S Raychaudhuri, I Kohane, E Karlson, RM Plenge. (2011)
\nAm J Hum Genet<\/em>\u00a088<\/b>(1): 57-69. doi: 10.1016\/j.ajhg.2010.12.007<\/p>\n<\/div>\n<\/div>\n
\nZhernakova A, EA Stahl, G Trynka, S Raychaudhuri, EA Festen, …, PIW de Bakker, PK Gregersen, J Worthington, KA Siminovitch, L Klareskog, TW Huizinga, C Wijmenga, RM Plenge. (2011)
\nPLoS Genetics<\/em>\u00a07<\/b>(2): e1002004. doi: 10.1371\/journal.pgen.1002004<\/p>\n<\/div>\n<\/div>\n
\nStahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, Li Y, Kurreeman FA, Zhernakova A, Hinks A, Guiducci C, Chen R, Alfredsson L, Amos CI, Ardlie KG; BIRAC Consortium, Barton A, Bowes J, Brouwer E, Burtt NP, Catanese JJ, Coblyn J, Coenen MJ, Costenbader KH, Criswell LA, Crusius JB, Cui J, de Bakker PI, De Jager PL, …, YEAR Consortium, Wijmenga C, Karlson EW, Toes RE, de Vries N, Begovich AB, Worthington J, Siminovitch KA, Gregersen PK, Klareskog L, Plenge RM. (2010)
\nNature Genet.\u00a0<\/em>42<\/b>(6):508-14. doi: 10.1038\/ng.582. Epub 2010 May 9. [PubMed<\/a>]<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"