Postdoctoral fellow/Senior scientist (Cancer genomics/single-cell & spatial sequencing)

The Song Lab at Icahn school of medicine at Mount Sinai (ISMMS) is seeking talented individuals who can advance the forefront of bladder cancer researches to apply for post-doctoral/Senior Scientist positions in our lab. Our interdisciplinary bladder cancer team led by Dr. Won-Min Song (computational biologist), Dr. Amir Horowitz (cancer immunologist) and Dr. John Sfakianos (urologist) is leading the cutting-edge science to tackle Bacillus Calmette-Guérin (BCG) vaccine resistance in non-muscle invasive bladder cancers (NMIBC). The team has recently secured NCI R01 funding to undertake multi-scale modeling of BCG-resistant NMIBC micro-environment. Under the supervision of Drs. Song and Horowitz, the appointee will lead the efforts to generate and analyze the first single-cell genomic atlas of NMIBC using the state-of-art machine learning and AI-oriented approaches developed by Dr. Song and his team, and identify feasible therapeutic strategies to abolish the BCG resistance.

 

The Position

This position will help building a collaboration network across multiple institutes and a track record that enables to apply for collaborative research funding and independent research fellowship. Specific roles include (but not limited to) the following:

Essential:

  • Lead and carry out research projects in the broad area of systems biology, single-cell multi-omics and spatial genomics,
  • Familiarity with molecular network modeling,
  • Expertise in cancer genomics,
  • Prepare and publish work on scientific journals and present scientific results in national/international conferences.
  • Develop and co-supervise research projects for undergraduate and graduate research students.
  • Build collaboration with different labs in ISMMS and across multiple institutes/universities at New York and beyond.

Preferred:

  • Knowledge in bladder cancer and cancer immunology/immunotherapy,
  • Expertise to leverage and apply AI/machine learning techniques

The Person

  • A PhD in computational biology, bioinformatics, computer science, physics, mathematics and molecular biology or another closely related scientific discipline,
  • Proven research ability, and evidence of self-motivation and research potential
  • Demonstrated experience with omics, bioinformatics, systems biology and molecular biology,
  • Demonstrated experience with data analytics and statistical modelling of single-cell multi-omics and spatially resolved genomics data,
  • Proven ability and commitment to producing high quality work, including at least one first author publication in a high impact journal,
  • Proven ability to write and contribute to bioinformatic, computational, statistical, or mathematical research papers,
  • Proven excellence in written and oral communications, interacting with a variety of researchers and stakeholders,
  • Under-represented groups (see Women, Minorities, and Persons with Disabilities in Science and Engineering: https://diversity.nih.gov/about-us/population-underrepresented) in biomedical sciences are strongly encouraged to apply.
  • Familiar with single-cell genomics. Experience with spatial transcriptome is a plus.

Interested and qualified candidates may inquire about positions by submitting a CV, a detailed letter of interest and contact details of three referees to Associate Professor Won-Min Song (won-min.song@mssm.edu).