{"id":11,"date":"2016-03-21T16:03:11","date_gmt":"2016-03-21T16:03:11","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/sidilab\/?page_id=11"},"modified":"2023-09-26T22:36:22","modified_gmt":"2023-09-26T22:36:22","slug":"meet-the-team","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/sidilab\/meet-the-team\/","title":{"rendered":"Meet the Team"},"content":{"rendered":"

\"Sidi\"<\/a>\"france\"<\/a>Samuel Sidi, PhD<\/a>\u00a0
\n<\/span>PROFESSOR
\n<\/span>Developmental & Regenerative Biology
\n<\/span>Medicine (Division of Hematology and Medical Oncology)
\n<\/span><\/a>Oncological Sciences\u00a0<\/span><\/p>\n

 <\/p>\n

\"photo-6\"<\/a>\"japan\"<\/a>Ando, William Kiyohiro
\nPOSTDOCTORAL FELLOW
\nwilliam.ando@mssm.edu
\n<\/a><\/p>\n

I am focusing on the mechanism of caspase-2 activation in the Chk1-suppressed apoptotic pathway. I am also working on a genome-wide siena screen for new pathway components.<\/p>\n

\"droppedImage_1\"<\/a> \"unitedstates\"<\/a>Closser, Evan
\nRESEARCH ASSOCIATE
\nevan.closser@mssm.edu<\/a><\/p>\n

Zebrafish Facility<\/a> Manager<\/p>\n

\"photo-20\"<\/a>\"italy\"<\/a>Di Giandomenico, Silvana
\nPOSTDOCTORAL FELLOW
\nsilvana.digiandomenico@mssm.edu<\/a><\/p>\n

My research seeks to define the genetic determinants of tumor cell response to radiation plus Chk1 inhibition. I am screening large panels of genotypical annotated cancer cell lines for their ability to activate caspase-2 after treatment. Candidate predictive genotypes are then validated in zebrafish, ex vivo patient cultures, xenograft models.<\/p>\n

\"photo-5\"<\/a>\"unitedstates\"<\/a>Kernan, Jennifer
\nRESEARCH COORDINATOR
\njennifer.kernan@mssm.edu<\/a><\/p>\n

I am interested in the molecular events that lead to the execution of the Chk1-suppressed apoptotic program downstream of caspase-2 activation. Specifically, I am searching for regulators and substrates of this caspase using genetic and proteomic approaches.<\/p>\n

\"droppedImage\"<\/a> \"unitedstates\"<\/a>Liu, Peter
\nSTUDENT
\npeter.hongdau@gmail.com<\/a><\/p>\n

I seek to find novel compounds that are synthetically lethal to p53 deficiency using zebrafish as a high-throughput screening system for small-molecule inhibitors.<\/p>\n

\"droppedImage_3\"<\/a>\"unitedkingdom\"<\/a>Thompson, Ruth
\nPOSTDOCTORAL FELLOW
\nruth.thompson@mssm.edu<\/a><\/p>\n

My work focuses on the mechanism by which Chk1 negatively regulates PIDDosome assembly and activation in the Chk1-suppressed apoptotic pathway. I am also using a genome-wide siRNA screen to identify new pathway components.<\/p>\n

\"droppedImage_2\"<\/a>\"unitedstates\"<\/a>Mernacej, Jolanda
\nADMINISTRATIVE ASSISTANT
\njolanda.mernacej@mssm.edu<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Samuel Sidi, PhD\u00a0 PROFESSOR Developmental & Regenerative Biology Medicine (Division of Hematology and Medical Oncology) Oncological Sciences\u00a0   Ando, William Kiyohiro POSTDOCTORAL FELLOW william.ando@mssm.edu I am focusing on the mechanism of caspase-2 activation in the Chk1-suppressed apoptotic pathway. I am also working on a genome-wide siena screen for new pathway components. Closser, Evan RESEARCH ASSOCIATE […]<\/p>\n","protected":false},"author":393,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-11","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/sidilab\/wp-json\/wp\/v2\/pages\/11","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/sidilab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/sidilab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/sidilab\/wp-json\/wp\/v2\/users\/393"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/sidilab\/wp-json\/wp\/v2\/comments?post=11"}],"version-history":[{"count":44,"href":"https:\/\/labs.icahn.mssm.edu\/sidilab\/wp-json\/wp\/v2\/pages\/11\/revisions"}],"predecessor-version":[{"id":125,"href":"https:\/\/labs.icahn.mssm.edu\/sidilab\/wp-json\/wp\/v2\/pages\/11\/revisions\/125"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/sidilab\/wp-json\/wp\/v2\/media?parent=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}