{"id":11,"date":"2015-06-12T15:08:56","date_gmt":"2015-06-12T19:08:56","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/shawlab\/?page_id=11"},"modified":"2015-06-12T15:08:56","modified_gmt":"2015-06-12T19:08:56","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/shawlab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

For the full list of Dr. Shaw’s publications,\u00a0click here<\/a>.<\/p>\n

M. R. Edwards, C. Pietzsch, T. Vausselin, M. L. Shaw, A. Bukreyev, C. F. Basler, High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication. ACS infectious diseases,\u00a0 (2015); published online Epub2015\/06\/17 (10.1021\/acsinfecdis.5b00053).<\/p>\n

K. M. White, P. De Jesus, Z. Chen, P. Abreu, Jr., E. Barile, P. A. Mak, P. Anderson, Q. T. Nguyen, A. Inoue, S. Stertz, R. Koenig, M. Pellecchia, P. Palese, K. Kuhen, A. Garcia-Sastre, S. K. Chanda, M. L. Shaw, A Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemagglutinin Protein.\u00a0ACS infectious diseases<\/em>\u00a01<\/strong>, 98-109 (2015); published online EpubFeb 13 (10.1021\/id500022h).<\/p>\n

N. B. Glennon, O. Jabado, M. K. Lo, M. L. Shaw, Transcriptome profiling of the virus-induced innate immune response in Pteropus vampyrus and its attenuation by Nipah virus interferon antagonist functions.\u00a0Journal of virology<\/em>,\u00a0 (2015); published online EpubMay 13 (10.1128\/jvi.00302-15).<\/p>\n

E. Ortiz-Riano, N. Ngo, S. Devito, D. Eggink, J. Munger, M. L. Shaw, J. C. de la Torre, L. Martinez-Sobrido, Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor.\u00a0Journal of virology<\/em>\u00a088<\/strong>, 878-889 (2014); published online EpubJan (10.1128\/jvi.02275-13).<\/p>\n

M. L. Shaw, K. Klumpp, Successes and challenges in the antiviral field.\u00a0Current opinion in virology<\/em>\u00a03<\/strong>, 483-486 (2013); published online EpubOct (10.1016\/j.coviro.2013.08.015).<\/p>\n

L. Martinez-Gil, P. H. Goff, R. Hai, A. Garcia-Sastre, M. L. Shaw, P. Palese, A Sendai virus-derived RNA agonist of RIG-I as a virus vaccine adjuvant.\u00a0Journal of virology<\/em>\u00a087<\/strong>, 1290-1300 (2013); published online EpubFeb (10.1128\/jvi.02338-12).<\/p>\n

G. Beyleveld, K. M. White, J. Ayllon, M. L. Shaw, New-generation screening assays for the detection of anti-influenza compounds targeting viral and host functions.\u00a0Antiviral Res<\/em>\u00a0100<\/strong>, 120-132 (2013); published online EpubOct (10.1016\/j.antiviral.2013.07.018).<\/p>\n

J. G. Alamares-Sapuay, L. Martinez-Gil, S. Stertz, M. S. Miller, M. L. Shaw, P. Palese, Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus.\u00a0Journal of virology<\/em>\u00a087<\/strong>, 6020-6026 (2013); published online EpubMay (10.1128\/jvi.01258-12).<\/p>\n

Shaw ML, Palese P (2013) Orthomyxoviridae: The viruses and their replication. In: Fields Virology 6th edition. Knipe DM, Howley PM, eds, pp 1691\u20131740, Lippincott Williams & Wilkins, Philadelphia.<\/p>\n

M. B. Ortigoza, O. Dibben, J. Maamary, L. Martinez-Gil, V. H. Leyva-Grado, P. Abreu, Jr., J. Ayllon, P. Palese, M. L. Shaw, A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon.\u00a0PLoS pathogens<\/em>\u00a08<\/strong>, e1002668 (2012)10.1371\/journal.ppat.1002668).<\/p>\n

L. Martinez-Gil, J. Ayllon, M. B. Ortigoza, A. Garcia-Sastre, M. L. Shaw, P. Palese, Identification of small molecules with type I interferon inducing properties by high-throughput screening.\u00a0Plos One<\/em>\u00a07<\/strong>, e49049 (2012)10.1371\/journal.pone.0049049).<\/p>\n

S. Stertz, M. L. Shaw, Uncovering the global host cell requirements for influenza virus replication via RNAi screening.\u00a0Microbes and infection \/ Institut Pasteur<\/em>\u00a013<\/strong>, 516-525 (2011); published online EpubMay (10.1016\/j.micinf.2011.01.012).<\/p>\n

M. L. Shaw, The host interactome of influenza virus presents new potential targets for antiviral drugs.\u00a0Reviews in medical virology<\/em>\u00a021<\/strong>, 358-369 (2011); published online EpubNov (10.1002\/rmv.703).<\/p>\n

H. H. Hoffmann, A. Kunz, V. A. Simon, P. Palese, M. L. Shaw, Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.\u00a0Proceedings of the National Academy of Sciences of the United States of America<\/em>\u00a0108<\/strong>, 5777-5782 (2011); published online EpubApr 5 (10.1073\/pnas.1101143108).<\/p>\n

J. Seto, L. Qiao, C. A. Guenzel, S. Xiao, M. L. Shaw, F. Hayot, S. C. Sealfon, Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study.\u00a0Journal of virology<\/em>\u00a084<\/strong>, 10965-10973 (2010); published online EpubNov (10.1128\/jvi.01335-10).<\/p>\n

R. Konig, S. Stertz, Y. Zhou, A. Inoue, H. H. Hoffmann, S. Bhattacharyya, J. G. Alamares, D. M. Tscherne, M. B. Ortigoza, Y. Liang, Q. Gao, S. E. Andrews, S. Bandyopadhyay, P. De Jesus, B. P. Tu, L. Pache, C. Shih, A. Orth, G. Bonamy, L. Miraglia, T. Ideker, A. Garcia-Sastre, J. A. Young, P. Palese, M. L. Shaw, S. K. Chanda, Human host factors required for influenza virus replication.\u00a0Nature<\/em>\u00a0463<\/strong>, 813-817 (2010); published online EpubFeb 11 (10.1038\/nature08699).<\/p>\n

M. L. Shaw, Henipaviruses employ a multifaceted approach to evade the antiviral interferon response.\u00a0Viruses<\/em>\u00a01<\/strong>, 1190-1203 (2009); published online EpubDec (10.3390\/v1031190).<\/p>\n

S. Kulkarni, V. Volchkova, C. F. Basler, P. Palese, V. E. Volchkov, M. L. Shaw, Nipah virus edits its P gene at high frequency to express the V and W proteins.\u00a0Journal of virology<\/em>\u00a083<\/strong>, 3982-3987 (2009); published online EpubApr (10.1128\/jvi.02599-08).<\/p>\n

M. J. Ciancanelli, V. A. Volchkova, M. L. Shaw, V. E. Volchkov, C. F. Basler, Nipah virus sequesters inactive STAT1 in the nucleus via a P gene-encoded mechanism.\u00a0Journal of virology<\/em>\u00a083<\/strong>, 7828-7841 (2009); published online EpubAug (10.1128\/jvi.02610-08).<\/p>\n

M. L. Shaw, K. L. Stone, C. M. Colangelo, E. E. Gulcicek, P. Palese, Cellular proteins in influenza virus particles.\u00a0PLoS pathogens<\/em>\u00a04<\/strong>, e1000085 (2008); published online EpubJun (10.1371\/journal.ppat.1000085).<\/p>\n

H. H. Hoffmann, P. Palese, M. L. Shaw, Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity.\u00a0Antiviral Res<\/em>\u00a080<\/strong>, 124-134 (2008); published online EpubNov (10.1016\/j.antiviral.2008.05.008).<\/p>\n","protected":false},"excerpt":{"rendered":"

For the full list of Dr. Shaw’s publications,\u00a0click here. M. R. Edwards, C. Pietzsch, T. Vausselin, M. L. Shaw, A. Bukreyev, C. F. Basler, High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication. ACS infectious diseases,\u00a0 (2015); published online Epub2015\/06\/17 (10.1021\/acsinfecdis.5b00053). K. M. White, P. De Jesus, Z. Chen, P. Abreu, Jr., E. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"open","ping_status":"closed","template":"full-width.php","meta":{"footnotes":""},"class_list":["post-11","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/shawlab\/wp-json\/wp\/v2\/pages\/11","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/shawlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/shawlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/shawlab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/shawlab\/wp-json\/wp\/v2\/comments?post=11"}],"version-history":[{"count":0,"href":"https:\/\/labs.icahn.mssm.edu\/shawlab\/wp-json\/wp\/v2\/pages\/11\/revisions"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/shawlab\/wp-json\/wp\/v2\/media?parent=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}