Publications

For the full list of Dr. Shaw’s publications, click here.

M. R. Edwards, C. Pietzsch, T. Vausselin, M. L. Shaw, A. Bukreyev, C. F. Basler, High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication. ACS infectious diseases,  (2015); published online Epub2015/06/17 (10.1021/acsinfecdis.5b00053).

K. M. White, P. De Jesus, Z. Chen, P. Abreu, Jr., E. Barile, P. A. Mak, P. Anderson, Q. T. Nguyen, A. Inoue, S. Stertz, R. Koenig, M. Pellecchia, P. Palese, K. Kuhen, A. Garcia-Sastre, S. K. Chanda, M. L. Shaw, A Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemagglutinin Protein. ACS infectious diseases 1, 98-109 (2015); published online EpubFeb 13 (10.1021/id500022h).

N. B. Glennon, O. Jabado, M. K. Lo, M. L. Shaw, Transcriptome profiling of the virus-induced innate immune response in Pteropus vampyrus and its attenuation by Nipah virus interferon antagonist functions. Journal of virology,  (2015); published online EpubMay 13 (10.1128/jvi.00302-15).

E. Ortiz-Riano, N. Ngo, S. Devito, D. Eggink, J. Munger, M. L. Shaw, J. C. de la Torre, L. Martinez-Sobrido, Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor. Journal of virology 88, 878-889 (2014); published online EpubJan (10.1128/jvi.02275-13).

M. L. Shaw, K. Klumpp, Successes and challenges in the antiviral field. Current opinion in virology 3, 483-486 (2013); published online EpubOct (10.1016/j.coviro.2013.08.015).

L. Martinez-Gil, P. H. Goff, R. Hai, A. Garcia-Sastre, M. L. Shaw, P. Palese, A Sendai virus-derived RNA agonist of RIG-I as a virus vaccine adjuvant. Journal of virology 87, 1290-1300 (2013); published online EpubFeb (10.1128/jvi.02338-12).

G. Beyleveld, K. M. White, J. Ayllon, M. L. Shaw, New-generation screening assays for the detection of anti-influenza compounds targeting viral and host functions. Antiviral Res 100, 120-132 (2013); published online EpubOct (10.1016/j.antiviral.2013.07.018).

J. G. Alamares-Sapuay, L. Martinez-Gil, S. Stertz, M. S. Miller, M. L. Shaw, P. Palese, Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus. Journal of virology 87, 6020-6026 (2013); published online EpubMay (10.1128/jvi.01258-12).

Shaw ML, Palese P (2013) Orthomyxoviridae: The viruses and their replication. In: Fields Virology 6th edition. Knipe DM, Howley PM, eds, pp 1691–1740, Lippincott Williams & Wilkins, Philadelphia.

M. B. Ortigoza, O. Dibben, J. Maamary, L. Martinez-Gil, V. H. Leyva-Grado, P. Abreu, Jr., J. Ayllon, P. Palese, M. L. Shaw, A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon. PLoS pathogens 8, e1002668 (2012)10.1371/journal.ppat.1002668).

L. Martinez-Gil, J. Ayllon, M. B. Ortigoza, A. Garcia-Sastre, M. L. Shaw, P. Palese, Identification of small molecules with type I interferon inducing properties by high-throughput screening. Plos One 7, e49049 (2012)10.1371/journal.pone.0049049).

S. Stertz, M. L. Shaw, Uncovering the global host cell requirements for influenza virus replication via RNAi screening. Microbes and infection / Institut Pasteur 13, 516-525 (2011); published online EpubMay (10.1016/j.micinf.2011.01.012).

M. L. Shaw, The host interactome of influenza virus presents new potential targets for antiviral drugs. Reviews in medical virology 21, 358-369 (2011); published online EpubNov (10.1002/rmv.703).

H. H. Hoffmann, A. Kunz, V. A. Simon, P. Palese, M. L. Shaw, Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 108, 5777-5782 (2011); published online EpubApr 5 (10.1073/pnas.1101143108).

J. Seto, L. Qiao, C. A. Guenzel, S. Xiao, M. L. Shaw, F. Hayot, S. C. Sealfon, Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study. Journal of virology 84, 10965-10973 (2010); published online EpubNov (10.1128/jvi.01335-10).

R. Konig, S. Stertz, Y. Zhou, A. Inoue, H. H. Hoffmann, S. Bhattacharyya, J. G. Alamares, D. M. Tscherne, M. B. Ortigoza, Y. Liang, Q. Gao, S. E. Andrews, S. Bandyopadhyay, P. De Jesus, B. P. Tu, L. Pache, C. Shih, A. Orth, G. Bonamy, L. Miraglia, T. Ideker, A. Garcia-Sastre, J. A. Young, P. Palese, M. L. Shaw, S. K. Chanda, Human host factors required for influenza virus replication. Nature 463, 813-817 (2010); published online EpubFeb 11 (10.1038/nature08699).

M. L. Shaw, Henipaviruses employ a multifaceted approach to evade the antiviral interferon response. Viruses 1, 1190-1203 (2009); published online EpubDec (10.3390/v1031190).

S. Kulkarni, V. Volchkova, C. F. Basler, P. Palese, V. E. Volchkov, M. L. Shaw, Nipah virus edits its P gene at high frequency to express the V and W proteins. Journal of virology 83, 3982-3987 (2009); published online EpubApr (10.1128/jvi.02599-08).

M. J. Ciancanelli, V. A. Volchkova, M. L. Shaw, V. E. Volchkov, C. F. Basler, Nipah virus sequesters inactive STAT1 in the nucleus via a P gene-encoded mechanism. Journal of virology 83, 7828-7841 (2009); published online EpubAug (10.1128/jvi.02610-08).

M. L. Shaw, K. L. Stone, C. M. Colangelo, E. E. Gulcicek, P. Palese, Cellular proteins in influenza virus particles. PLoS pathogens 4, e1000085 (2008); published online EpubJun (10.1371/journal.ppat.1000085).

H. H. Hoffmann, P. Palese, M. L. Shaw, Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity. Antiviral Res 80, 124-134 (2008); published online EpubNov (10.1016/j.antiviral.2008.05.008).