{"id":1492,"date":"2022-11-18T07:09:04","date_gmt":"2022-11-18T12:09:04","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/design\/?page_id=1492"},"modified":"2024-10-17T11:15:27","modified_gmt":"2024-10-17T15:15:27","slug":"about-us","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/saxenalab\/about-us\/","title":{"rendered":"About Us"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Fullwidth Header &#8211; Background Title &#8211; no slider &#8211; Section 1&#8243; module_class=&#8221;section1_fullwidth_header_bg_title_no_slider-about_us&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_start=&#8221;#141414&#8243; background_color_gradient_end=&#8221;rgba(20,20,20,0.15)&#8221; background_color_gradient_direction=&#8221;1deg&#8221; background_color_gradient_end_position=&#8221;70%&#8221; background_color_gradient_overlays_image=&#8221;on&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2022\/08\/DC-Sox2GFP-SOX2-ITGA6-E15.0_02MR.jpg&#8221; background_position=&#8221;top_center&#8221; custom_padding=&#8221;||||false|false&#8221; bottom_divider_style=&#8221;ramp2&#8243; bottom_divider_color=&#8221;#FFFFFF&#8221; bottom_divider_height=&#8221;11vw&#8221; bottom_divider_arrangement=&#8221;above_content&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; border_color_all=&#8221;RGBA(0,0,0,0)&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;10%||8vw||false|false&#8221; custom_padding_tablet=&#8221;0vw||0vw||true|false&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221;][et_pb_text admin_label=&#8221;Text &#8211; Title&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;b3e3ff14-5f5c-4608-8ecf-1885ce3da7aa&#8221; header_font=&#8221;||||||||&#8221; header_text_align=&#8221;center&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;48px&#8221; header_line_height=&#8221;60px&#8221; custom_margin=&#8221;||10px||false|false&#8221; header_font_size_tablet=&#8221;40px&#8221; header_font_size_phone=&#8221;24px&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221;]<\/p>\n<h1><strong>About Us<\/strong><\/h1>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Fullwidth Text Over White Background &#8211; Section&#8221; module_class=&#8221;section_fulllwidth_text_simple&#8221; _builder_version=&#8221;4.9.0&#8243; locked=&#8221;off&#8221; collapsed=&#8221;off&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; admin_label=&#8221;row&#8221; _builder_version=&#8221;4.9.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; border_width_bottom=&#8221;3px&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;34px&#8221; custom_padding=&#8221;||0px|||&#8221;]<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-size: 16px;font-family: HelveticaNeueETW01-55Rg, Helvetica, Arial, sans-serif\">\u00a0<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Text&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; header_text_color=&#8221;#00a6e5&#8243; custom_margin=&#8221;-21px|||||&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h1>Who We Are<\/h1>\n<p style=\"font-weight: 400\">The VCTL is an academic cGMP laboratory with the aim of providing expert advice and cGMP and GLP services that help investigators, clinician scientists and small biopharmaceutical companies in initiating early phase clinical trials. Since becoming functional in 2015, the VCTL has produced personalized cancer vaccines, shared antigen cancer vaccines, stem cell infusion products, cell-based vaccines, Influenza vaccine seeds and most recently live virus vaccines against Covid-19.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-content\/uploads\/sites\/504\/2024\/05\/IMG_08531-scaled.jpg&#8221; title_text=&#8221;IMG_0853(1)&#8221; admin_label=&#8221;Image&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; border_width_all=&#8221;1px&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_start=&#8221;#000000&#8243; background_color_gradient_end=&#8221;#ffffff&#8221; background_color_gradient_direction=&#8221;90deg&#8221; sticky_enabled=&#8221;0&#8243; background_color_gradient_end_position=&#8221;75%&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#FFFFFF&#8221;]<\/p>\n<h2 style=\"padding-left: 30px;text-align: center\"><span style=\"text-decoration: underline\">Our Philosophy<\/span><\/h2>\n<p style=\"padding-left: 30px\">The Vaccine and Cell Therapy Laboratory (VCTL) serves an important role in translating promising laboratory results into novel therapies by providing a dedicated and controlled facility for the manufacturing of immunotherapies and testing their effectiveness in vaccinated patients for phase I and II clinical trials in cancer and infectious diseases.\u00a0 This highly specialized facility is an essential component of the\u00a0<a href=\"http:\/\/icahn.mssm.edu\/research\/institutes\/tisch-cancer-institute\/cancer-research\/research-programs\/cancer-immunology\">Tisch Cancer Institute\u2019s Immunotherapy Program<\/a>.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; custom_padding=&#8221;|14px|||false|false&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h2 style=\"text-align: center\"><span style=\"text-decoration: underline\">Our Mission<\/span><\/h2>\n<p>To advance translational research and development in the fields of immuno-therapeutics, cell therapies and neoantigen vaccines through collaborations with academic investigators and\u00a0industry partners.<\/p>\n<p style=\"padding-left: 30px\"><span style=\"text-decoration: underline\"><\/span><\/p>\n<p><span style=\"text-decoration: underline\"><\/span><\/p>\n<p><span style=\"text-decoration: underline\"><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Option2 Section25 \u2013 Fullwidth Footer \u2013 Local&#8221; module_class=&#8221;footer-section&#8221; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#221F72&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_end=&#8221;#58595b&#8221; background_enable_image=&#8221;off&#8221; max_width=&#8221;100%&#8221; max_width_tablet=&#8221;&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|phone&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;0px|||176px|false|false&#8221; custom_padding=&#8221;3px|0px|0px|0px|false|false&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;bottom&#8221; animation_intensity_slide=&#8221;14%&#8221; animation_starting_opacity=&#8221;100%&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_color_gradient_direction=&#8221;38deg&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto||147px||&#8221; locked=&#8221;off&#8221; collapsed=&#8221;off&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_social_media_follow _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; text_orientation=&#8221;center&#8221;][et_pb_social_media_follow_network social_network=&#8221;linkedin&#8221; url=&#8221;https:\/\/www.linkedin.com\/school\/icahnmountsinai\/%20&#8243; use_icon_font_size=&#8221;on&#8221; icon_font_size=&#8221;24px&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_enable_color=&#8221;on&#8221; follow_button=&#8221;off&#8221; url_new_window=&#8221;on&#8221;]linkedin[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=&#8221;facebook&#8221; url=&#8221;https:\/\/www.facebook.com\/IcahnMountSinai&#8221; use_icon_font_size=&#8221;on&#8221; icon_font_size=&#8221;24px&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_enable_color=&#8221;on&#8221; follow_button=&#8221;off&#8221; url_new_window=&#8221;on&#8221;]facebook[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=&#8221;twitter&#8221; url=&#8221;https:\/\/twitter.com\/icahnmountsinai&#8221; use_icon_font_size=&#8221;on&#8221; icon_font_size=&#8221;24px&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_enable_color=&#8221;on&#8221; follow_button=&#8221;off&#8221; url_new_window=&#8221;on&#8221;]twitter[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=&#8221;youtube&#8221; url=&#8221;https:\/\/www.youtube.com\/user\/MountSinaiSchool&#8221; use_icon_font_size=&#8221;on&#8221; icon_font_size=&#8221;24px&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_enable_color=&#8221;on&#8221; follow_button=&#8221;off&#8221; url_new_window=&#8221;on&#8221;]youtube[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=&#8221;instagram&#8221; url=&#8221;https:\/\/www.instagram.com\/icahnmountsinai\/&#8221; use_icon_font_size=&#8221;on&#8221; icon_font_size=&#8221;24px&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_enable_color=&#8221;on&#8221; follow_button=&#8221;off&#8221; url_new_window=&#8221;on&#8221;]instagram[\/et_pb_social_media_follow_network][\/et_pb_social_media_follow][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;24px&#8221;]<\/p>\n<p style=\"text-align: center\"><strong>Contact Us<\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_4,1_4,1_4,1_4&#8243; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_color_gradient_direction=&#8221;38deg&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto|-2px|auto||&#8221; custom_padding=&#8221;0px|||||&#8221; locked=&#8221;off&#8221; collapsed=&#8221;off&#8221;][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.9.0&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;22px&#8221;]<\/p>\n<h3 class=\"widget-title\"><span style=\"color: #00ccff\">Related Resources<\/span><\/h3>\n<div class=\"textwidget\"><a href=\"http:\/\/icahn.mssm.edu\/research\/institutes\/tisch-cancer-institute\/cancer-research\/research-programs\/cancer-immunology\"><span style=\"color: #ccffff\">Cancer Immunology Program<\/span><\/a><br \/><span style=\"color: #ccffff\"><a href=\"http:\/\/icahn.mssm.edu\/research-portal\/clinical-trials\" style=\"color: #ccffff\">Clinical Trials<\/a><\/span><br \/><span style=\"color: #ccffff\"><a href=\"http:\/\/icahn.mssm.edu\/research\/resources\/shared-resource-facilities\/human-immune-monitoring-core-shared-facilities\" title=\"Human Immune Monitoring Core\" style=\"color: #ccffff\">Human Immune Monitoring Core<\/a><\/span><br \/><span style=\"color: #ccffff\"><a href=\"http:\/\/www.mountsinai.org\/health-professionals\/pharmacy-services\/investigational-drug-service\" title=\"Investigational Drug Service\" style=\"color: #ccffff\">Investigational Drug Service<\/a><\/span><br \/><span style=\"color: #ccffff\"><a href=\"http:\/\/icahn.mssm.edu\/research\/resources\/office-of-clinical-research\/resources-and-services\" style=\"color: #ccffff\">Office of Research Services<\/a><\/span><br \/><span style=\"color: #ccffff\"><a href=\"http:\/\/icahn.mssm.edu\/research\/resources\/program-for-the-protection-of-human-subjects\" title=\"Program for Protection of Human Subjects\" style=\"color: #ccffff\">Program for Protection of Human Subjects<\/a><\/span><br \/><span style=\"color: #ccffff\"><a href=\"http:\/\/icahn.mssm.edu\/research\/institutes\/tisch-cancer-institute\" style=\"color: #ccffff\">Tisch Cancer Institute<\/a><\/span><\/div>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221;]<\/p>\n<p><strong>E-mail<br \/> <\/strong><a href=\"mailto:vaccinecore@mssm.edu\">vaccinecore@mssm.edu<\/a><\/p>\n<p><strong>Phone<br \/> <\/strong>Tel: 212-824-8439<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221;]<strong>Lab Address<\/strong><br \/>\n1470 Madison Avenue<br \/>\nHess Building 5-102<br \/>\nNew York, NY 10029<\/p>\n<p>&nbsp;<br \/>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;]<span style=\"color: #ffffff\"><strong>Mailing Address <\/strong><\/span><\/p>\n<p><span style=\"color: #ffffff\">Vaccine and Cell Therapy Laboratory<\/span><br \/>\n<span style=\"color: #ffffff\"> Icahn School of Medicine<\/span><br \/>\n<span style=\"color: #ffffff\"> at Mount Sinai<\/span><br \/>\n<span style=\"color: #ffffff\"> 1470 Madison Avenue<\/span><br \/>\n<span style=\"color: #ffffff\"> Hess Building 5-102<\/span><br \/>\n<span style=\"color: #ffffff\"> New York, NY 10029<\/span><br \/>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>About Us &nbsp; \u00a0Who We Are The VCTL is an academic cGMP laboratory with the aim of providing expert advice and cGMP and GLP services that help investigators, clinician scientists and small biopharmaceutical companies in initiating early phase clinical trials. Since becoming functional in 2015, the VCTL has produced personalized cancer vaccines, shared antigen cancer [&hellip;]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p>[et_pb_section fb_built=\"1\" admin_label=\"Fullwidth Header - Background Title - no slider - Section 1\" module_class=\"section1_fullwidth_header_bg_title_no_slider-about_us\" _builder_version=\"4.9.0\" _module_preset=\"default\" background_enable_color=\"off\" use_background_color_gradient=\"on\" background_color_gradient_start=\"#141414\" background_color_gradient_end=\"rgba(20,20,20,0.15)\" background_color_gradient_direction=\"1deg\" background_color_gradient_end_position=\"70%\" background_color_gradient_overlays_image=\"on\" 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header_font_size=\"48px\" header_line_height=\"60px\" custom_margin=\"||10px||false|false\" header_font_size_tablet=\"40px\" header_font_size_phone=\"24px\" header_font_size_last_edited=\"on|desktop\"]<\/p><h1><strong>About Us<\/strong><\/h1><p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_2\" _builder_version=\"4.9.0\" _module_preset=\"default\" background_color=\"RGBA(0,0,0,0)\"][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" admin_label=\"Fullwidth Text Over White Background - Section\" module_class=\"section_fulllwidth_text_simple\" _builder_version=\"4.9.0\" locked=\"off\" collapsed=\"on\"][et_pb_row admin_label=\"row\" _builder_version=\"3.25\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"4_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.9.0\" _module_preset=\"default\" header_text_color=\"#00a6e5\"]<\/p><p>The Vaccine and Cell Therapy Laboratory (VCTL) serves an important role in translating promising laboratory results into novel therapies by providing a dedicated and controlled facility for the manufacturing of immunotherapies and testing their effectiveness in vaccinated patients for phase I and II clinical trials in cancer and infectious diseases.\u00a0 This highly specialized facility is an essential component of the\u00a0<a href=\"http:\/\/icahn.mssm.edu\/research\/institutes\/tisch-cancer-institute\/cancer-research\/research-programs\/cancer-immunology\">Tisch Cancer Institute\u2019s Immunotherapy Program<\/a>.<\/p><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"off|off|off\" admin_label=\"Fullwidth Video over Background - Section 9\" module_class=\"fullwidth-video-over-background-section-9\" _builder_version=\"4.9.0\" _module_preset=\"default\" background_color=\"#ededed\" background_image=\"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-content\/uploads\/sites\/504\/2022\/10\/4.png\" height_tablet=\"\" height_phone=\"\" height_last_edited=\"on|desktop\" max_height=\"100%\" custom_margin=\"||4%||false|false\" custom_padding=\"0px||0px||false|false\" hover_enabled=\"0\" locked=\"off\" collapsed=\"off\" sticky_enabled=\"0\"][et_pb_row column_structure=\"1_5,3_5,1_5\" _builder_version=\"4.9.0\" _module_preset=\"default\"][et_pb_column type=\"1_5\" _builder_version=\"4.9.0\" _module_preset=\"default\"][\/et_pb_column][et_pb_column type=\"3_5\" _builder_version=\"4.9.0\" _module_preset=\"default\"][et_pb_video src=\"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2022\/08\/DC0_45d_45d_zoom-in_10s_720p_1.9MB.mp4\" image_src=\"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-content\/uploads\/sites\/504\/2022\/08\/video2.png\" thumbnail_overlay_color=\"rgba(0,174,239,0.2)\" _builder_version=\"4.9.0\" _module_preset=\"default\" hover_enabled=\"0\" custom_css_video_icon=\"display: none;\" box_shadow_style=\"preset1\" box_shadow_spread=\"10px\" sticky_enabled=\"0\"][\/et_pb_video][\/et_pb_column][et_pb_column type=\"1_5\" _builder_version=\"4.9.0\" _module_preset=\"default\"][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" specialty=\"on\" admin_label=\"Two Column Video over Image Below Content - Section 11\" module_class=\"section-11-container\" _builder_version=\"4.9.0\" _module_preset=\"default\" background_enable_color=\"off\" width=\"70%\" module_alignment=\"center\" locked=\"off\" collapsed=\"on\"][et_pb_column type=\"1_2\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-content\/uploads\/sites\/504\/2022\/08\/907A4689-Sized.jpg\" title_text=\"907A4689-Sized\" module_class=\"section-11-left_column_image\" _builder_version=\"4.9.0\" width=\"153%\" width_tablet=\"\" width_phone=\"\" width_last_edited=\"on|phone\" max_width_tablet=\"400px\" max_width_phone=\"300px\" max_width_last_edited=\"on|desktop\" custom_margin=\"|||-6vw\" custom_margin_tablet=\"|||0vw\" custom_margin_phone=\"\" custom_margin_last_edited=\"on|tablet\" box_shadow_style=\"preset4\" box_shadow_horizontal=\"0px\" box_shadow_vertical=\"0px\" box_shadow_color=\"#FFFFFF\"][\/et_pb_image][\/et_pb_column][et_pb_column type=\"1_2\" specialty_columns=\"2\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_row_inner module_class=\"section-11-row_for_content\" _builder_version=\"4.9.0\" _module_preset=\"default\" custom_margin=\"|||120px|false|false\" custom_margin_tablet=\"|||0px|false|false\" custom_margin_phone=\"|||0px|false|false\" custom_margin_last_edited=\"on|desktop\"][et_pb_column_inner saved_specialty_column_type=\"1_2\" _builder_version=\"4.9.0\" _module_preset=\"default\"][et_pb_text _builder_version=\"4.9.0\" text_font=\"||||||||\" text_line_height=\"22px\" header_font=\"|700|||||||\" header_font_size=\"32px\" header_line_height=\"46px\" text_font_size_tablet=\"\" text_font_size_phone=\"15px\" text_font_size_last_edited=\"on|desktop\" header_font_size_tablet=\"40px\" header_font_size_phone=\"25px\" header_font_size_last_edited=\"on|phone\"]<\/p><h1>Stem Cell Niche Remodeling During Progenitor Regression<\/h1><p>We have recently uncovered that the Dermal Sheath \u2013 follicle-lining cells with unidentified physiological function (Martino et al, Experimental Dermatology 2021) \u2013 is a smooth muscle that contracts to propel regression, extrude the hair shaft, and physically relocate the niche to reach its essential stem cell-adjacent position (Heitman et al, Science 2020).<\/p><p>[\/et_pb_text][et_pb_button button_text=\"Lorem ipsum dolor\" button_alignment=\"left\" disabled_on=\"on|on|on\" _builder_version=\"4.9.0\" custom_button=\"on\" button_text_size=\"18px\" button_text_color=\"#FFFFFF\" button_bg_color=\"#D80B8C\" button_border_color=\"rgba(0,0,0,0)\" button_border_radius=\"0px\" button_font=\"||||||||\" button_icon=\"%%20%%\" button_icon_color=\"#FFFFFF\" button_on_hover=\"off\" background_layout=\"dark\" custom_margin=\"|0px||0px|false|false\" custom_padding=\"14px|14px|14px|14px|true|true\" custom_padding_last_edited=\"off|desktop\" button_bg_color_last_edited=\"off|tablet\" box_shadow_style=\"preset1\" box_shadow_color=\"#58595B\" disabled=\"on\" button_bg_color__hover_enabled=\"on\" button_bg_color__hover=\"#000000\" button_bg_enable_color__hover=\"on\" custom_padding__hover_enabled=\"on\" custom_padding__hover=\"|30px||\"][\/et_pb_button][et_pb_button button_url=\"https:\/\/labs.icahn.mssm.edu\/design\/option1-research\" button_text=\"Find Out More\" _builder_version=\"4.9.0\" _module_preset=\"default\" custom_button=\"on\" button_text_color=\"#FFFFFF\" button_bg_color=\"#D80B8C\" button_border_radius=\"0px\" box_shadow_style=\"preset1\" locked=\"off\"][\/et_pb_button][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner column_structure=\"1_2,1_2\" module_class=\"section-11-row_for_video\" _builder_version=\"4.9.0\" _module_preset=\"default\"][et_pb_column_inner type=\"1_2\" saved_specialty_column_type=\"1_2\" _builder_version=\"4.9.0\" _module_preset=\"default\"][et_pb_video src=\"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2022\/08\/DC0_45d_45d_zoom-in_10s_720p_1.9MB.mp4\" image_src=\"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-content\/uploads\/sites\/504\/2022\/08\/video2-1024x620.png\" thumbnail_overlay_color=\"rgba(0,0,0,0.6)\" _builder_version=\"4.9.0\" width=\"540px\" custom_margin=\"|||-100%\" custom_margin_tablet=\"|||0px\" custom_margin_phone=\"\" custom_margin_last_edited=\"on|phone\" custom_css_main_element=\"transform: scale(1.2,1);\" custom_css_video_icon=\"display: none;\" box_shadow_style=\"preset1\" box_shadow_vertical=\"80px\" box_shadow_blur=\"110px\" box_shadow_spread=\"-30px\" box_shadow_color=\"rgba(0,0,0,0.48)\"][\/et_pb_video][\/et_pb_column_inner][et_pb_column_inner type=\"1_2\" saved_specialty_column_type=\"1_2\" _builder_version=\"4.9.0\" _module_preset=\"default\"][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"off|off|off\" admin_label=\"Single Video Box - Section 12\" module_class=\"section-12-container\" _builder_version=\"4.9.0\" background_color=\"#00AEEF\" use_background_color_gradient=\"on\" background_color_gradient_end=\"#d80b8c\" background_color_gradient_type=\"radial\" background_color_gradient_direction_radial=\"top left\" background_color_gradient_start_position=\"50%\" background_image=\"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-content\/uploads\/sites\/504\/2022\/10\/Rectangle-3.png\" custom_margin=\"||100px||false|false\" custom_padding=\"3%||||false|false\" animation_style=\"zoom\" animation_direction=\"bottom\" animation_intensity_zoom=\"8%\" animation_starting_opacity=\"100%\" custom_css_main_element=\"padding-bottom: -5px !important;\" box_shadow_style=\"preset3\" box_shadow_vertical=\"-200px\" box_shadow_blur=\"0px\" box_shadow_color=\"#FFFFFF\" box_shadow_position=\"inner\" locked=\"off\" collapsed=\"on\"][et_pb_row _builder_version=\"4.9.0\" min_height=\"783.7px\" custom_padding=\"0px||0px|||\"][et_pb_column type=\"4_4\" _builder_version=\"4.9.0\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.9.0\" text_font=\"||||||||\" text_text_color=\"#ffffff\" text_font_size=\"18px\" text_line_height=\"23px\" header_font=\"|700|||||||\" header_text_align=\"center\" header_text_color=\"#FFFFFF\" header_font_size=\"36px\" header_line_height=\"46px\" header_2_font=\"||||||||\" text_orientation=\"center\" max_width=\"700px\" module_alignment=\"center\" custom_margin=\"|||274px||\"]<\/p><h1>Hair Growth Cycle<\/h1><p>Discover how tissues regenerate from stem cells and how different organs balance cell loss with new growth.<\/p><p>[\/et_pb_text][et_pb_video src=\"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2022\/08\/DC0_45d_45d_zoom-in_10s_720p_1.9MB.mp4\" image_src=\"<br \/>\" _builder_version=\"4.9.0\" _module_preset=\"default\" width=\"60vw\" custom_margin=\"|auto||auto|false|false\"][\/et_pb_video][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" disabled_on=\"off|off|off\" admin_label=\"Option2 Section25 \u2013 Fullwidth Footer \u2013 Local\" module_class=\"footer-section\" _builder_version=\"4.9.0\" background_color=\"#221F72\" use_background_color_gradient=\"on\" background_color_gradient_end=\"#58595b\" background_enable_image=\"off\" max_width=\"100%\" max_width_tablet=\"\" max_width_phone=\"\" max_width_last_edited=\"on|phone\" module_alignment=\"center\" custom_margin=\"0px|||176px|false|false\" custom_padding=\"3px|0px|0px|0px|false|false\" animation_style=\"slide\" animation_direction=\"bottom\" animation_intensity_slide=\"14%\" animation_starting_opacity=\"100%\" saved_tabs=\"all\" locked=\"off\" collapsed=\"on\"][et_pb_row _builder_version=\"4.9.0\" background_color=\"RGBA(0,0,0,0)\" background_color_gradient_direction=\"38deg\" module_alignment=\"center\" custom_margin=\"|auto||147px||\" locked=\"off\" collapsed=\"on\"][et_pb_column type=\"4_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_social_media_follow _builder_version=\"4.9.0\" _module_preset=\"default\" background_color=\"RGBA(0,0,0,0)\" text_orientation=\"center\"][et_pb_social_media_follow_network social_network=\"linkedin\" url=\"https:\/\/www.linkedin.com\/school\/icahnmountsinai\/%20\" use_icon_font_size=\"on\" icon_font_size=\"24px\" _builder_version=\"4.9.0\" _module_preset=\"default\" background_color=\"RGBA(0,0,0,0)\" background_enable_color=\"on\"]linkedin[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=\"facebook\" url=\"https:\/\/www.facebook.com\/IcahnMountSinai\" use_icon_font_size=\"on\" icon_font_size=\"24px\" _builder_version=\"4.9.0\" _module_preset=\"default\" background_color=\"RGBA(0,0,0,0)\" background_enable_color=\"on\"]facebook[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=\"twitter\" url=\"https:\/\/twitter.com\/icahnmountsinai\" use_icon_font_size=\"on\" icon_font_size=\"24px\" _builder_version=\"4.9.0\" _module_preset=\"default\" background_color=\"RGBA(0,0,0,0)\" background_enable_color=\"on\"]twitter[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=\"youtube\" url=\"https:\/\/www.youtube.com\/user\/MountSinaiSchool\" use_icon_font_size=\"on\" icon_font_size=\"24px\" _builder_version=\"4.9.0\" _module_preset=\"default\" background_color=\"RGBA(0,0,0,0)\" background_enable_color=\"on\"]youtube[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=\"instagram\" url=\"https:\/\/www.instagram.com\/icahnmountsinai\/\" use_icon_font_size=\"on\" icon_font_size=\"24px\" _builder_version=\"4.9.0\" _module_preset=\"default\" background_color=\"RGBA(0,0,0,0)\" background_enable_color=\"on\"]instagram[\/et_pb_social_media_follow_network][\/et_pb_social_media_follow][et_pb_text _builder_version=\"4.9.0\" _module_preset=\"default\" text_text_color=\"#FFFFFF\" text_font_size=\"24px\"]<\/p><p style=\"text-align: center;\"><strong>Contact Us<\/strong><\/p><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_4,1_4,1_4,1_4\" _builder_version=\"4.9.0\" background_color=\"RGBA(0,0,0,0)\" background_color_gradient_direction=\"38deg\" module_alignment=\"center\" custom_margin=\"|auto|-2px|auto||\" custom_padding=\"0px|||||\" locked=\"off\" collapsed=\"on\"][et_pb_column type=\"1_4\" _builder_version=\"4.9.0\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.9.0\" _module_preset=\"default\" text_font=\"||||||||\" text_text_color=\"#FFFFFF\" text_line_height=\"22px\"]<\/p><p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Contact Us<br \/><\/a><\/span><a style=\"font-size: 16px; color: #ffffff;\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Recent News<br \/><\/a><a style=\"font-size: 16px; color: #ffffff;\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Alumni<br \/><\/a><a style=\"font-size: 16px; color: #ffffff;\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Researchers<br \/><\/a><a style=\"font-size: 16px; color: #ffffff;\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Gallery<br \/><\/a><a style=\"font-size: 16px; color: #ffffff;\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Resources<br \/><\/a><a style=\"font-size: 16px; color: #ffffff;\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Submit Inquiry<br \/><\/a><a style=\"font-size: 16px; color: #ffffff;\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Resources<br \/><\/a><a style=\"font-size: 16px; color: #ffffff;\" href=\"https:\/\/labs.icahn.mssm.edu\/design\">Lab Trials<br \/>Accessibility<\/a><\/p><p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.9.0\" text_font=\"||||||||\" text_text_color=\"#FFFFFF\" text_line_height=\"1.25em\" header_font=\"||||||||\" header_4_font=\"|700||on|||||\" header_4_font_size=\"16px\" header_4_letter_spacing=\"1px\" header_4_line_height=\"1.5em\" background_layout=\"dark\" locked=\"off\"]<\/p><p><strong>E-mail<br \/><\/strong><a href=\"mailto:vaccinecore@mssm.edu\">vaccinecore@mssm.edu<\/a><\/p><p><strong>Phone<br \/><\/strong>Tel: 555-555-5555<\/p><p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.9.0\" text_font=\"||||||||\" text_text_color=\"#FFFFFF\" text_line_height=\"1.25em\" header_font=\"||||||||\" header_4_font=\"|700||on|||||\" header_4_font_size=\"16px\" header_4_letter_spacing=\"1px\" header_4_line_height=\"1.5em\" background_layout=\"dark\" locked=\"off\"]<\/p><p><strong>Lab Address<\/strong><br \/>1470 Madison Avenue<br \/>Hess Building 5-102<br \/>New York, NY 10029<\/p><p>\u00a0<\/p><p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\"1_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text _builder_version=\"4.9.0\" _module_preset=\"default\"]<\/p><p><span style=\"color: #ffffff;\"><strong>Mailing Address <\/strong><\/span><\/p><p><span style=\"color: #ffffff;\">Vaccine and Cell Therapy Laboratory<\/span><br \/><span style=\"color: #ffffff;\"> Icahn School of Medicine<\/span><br \/><span style=\"color: #ffffff;\"> at Mount Sinai<\/span><br \/><span style=\"color: #ffffff;\"> 1470 Madison Avenue<\/span><br \/><span style=\"color: #ffffff;\"> Hess Building 5-102<\/span><br \/><span style=\"color: #ffffff;\"> New York, NY 10029<\/span><\/p><p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-1492","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-json\/wp\/v2\/pages\/1492","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-json\/wp\/v2\/comments?post=1492"}],"version-history":[{"count":25,"href":"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-json\/wp\/v2\/pages\/1492\/revisions"}],"predecessor-version":[{"id":4815,"href":"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-json\/wp\/v2\/pages\/1492\/revisions\/4815"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/saxenalab\/wp-json\/wp\/v2\/media?parent=1492"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}