{"id":599,"date":"2018-09-26T18:55:58","date_gmt":"2018-09-26T18:55:58","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/roussos-lab\/?page_id=599"},"modified":"2024-01-05T16:00:03","modified_gmt":"2024-01-05T16:00:03","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/roussos-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.9.0″][et_pb_row _builder_version=”4.9.0″ background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”4_4″ _builder_version=”3.0.47″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_toggle title=”2024″ closed_toggle_background_color=”#eaeaea” icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2024″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ hover_enabled=”0″ border_radii=”on|6px|6px|6px|6px” border_width_all=”0.5px” border_color_all=”#00aeef” saved_tabs=”all” locked=”off” sticky_enabled=”0″ open=”on”]<\/p>\n

Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders.<\/a><\/b><\/p>\n

Ma Y, Bendl J,<\/b>\u00a0Hartley BJ,\u00a0Fullard JF,<\/b>\u00a0Abdelaal R, Ho SM,\u00a0Kosoy R,<\/b>\u00a0Gochman P, Rapoport J,\u00a0Hoffman GE<\/b>, Brennand KJ,\u00a0Roussos P.\u00a0<\/b>Biol Psychiatry. 2024 Jan 15. doi: 10.1016\/j.biopsych.2023.07.003. Epub 2023 Jul 14. PMID: 37454787<\/div>\n

[\/et_pb_toggle][et_pb_toggle title=”2023″ closed_toggle_background_color=”#eaeaea” icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2023″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ border_radii=”on|6px|6px|6px|6px” border_width_all=”0.5px” border_color_all=”#00aeef” saved_tabs=”all” locked=”off”]<\/p>\n

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QuadST: A Powerful and Robust Approach for Identifying Cell-Cell Interaction-Changed Genes on Spatially Resolved Transcriptomics.<\/a><\/strong><\/div>\n
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Choi J, Ehrlich ME,\u00a0Roussos P<\/b>, Wang P, Yuan GC, Song X. <\/span>bioRxiv. 2023 Dec 7. doi: 10.1101\/2023.12.04.570019. Preprint. <\/span>PMID:\u00a038106025<\/span><\/span><\/div>\n<\/div>\n
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Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing.<\/a><\/strong><\/p>\n

Humphrey J, Brophy E, Kosoy R, Zeng B<\/strong>, Coccia E, Mattei D, Ravi A, Efthymiou AG, Navarro E, Muller BZ, Snijders GJ, Allan A, M\u00fcnch A, Kitata RB, Kleopoulos SP, Argyriou S, Shao Z, Francoeur N, Tsai CF, Gritsenko MA, Monroe ME, Paurus VL, Weitz KK, Shi T, Sebra R, Liu T, de Witte LD, Goate AM, Bennett DA, Haroutunian V, Hoffman GE, Fullard JF,<\/strong>\u00a0Roussos P<\/b>, Raj T. <\/span>medRxiv. 2023 Dec 1. doi: 10.1101\/2023.12.01.23299073. Preprint. <\/span>PMID:\u00a038076956<\/span><\/span><\/div>\n<\/div>\n
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Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome.<\/a><\/strong><\/p>\n

Rahman S, Dong P,<\/strong> Apontes P, Fernando MB, Kosoy R, Townsley KG, Girdhar K, Bendl J,<\/strong> Shao Z, Misir R, Tsankova N, Kleopoulos SP,<\/strong> Brennand KJ, Fullard JF,<\/strong>\u00a0Roussos P. <\/b><\/span>Nucleic Acids Res. 2023 Nov 10. doi: 10.1093\/nar\/gkad798. <\/span>PMID:\u00a037811875<\/span><\/span><\/div>\n
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DeepGAMI: deep biologically guided auxiliary learning for multimodal integration and imputation to improve genotype-phenotype prediction.<\/a><\/strong><\/p>\n

Chandrashekar PB, Alatkar S, Wang J, Hoffman GE<\/strong>, He C, Jin T, Khullar S, Bendl J, Fullard JF,<\/strong>\u00a0Roussos P<\/b>, Wang D. <\/span>Genome Med. 2023 Oct 31. doi: 10.1186\/s13073-023-01248-6. <\/span>PMID:\u00a037904203<\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n
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A public resource of single cell transcriptomes and multiscale networks from persons with and without Alzheimer’s disease.<\/strong><\/a><\/p>\n

Wang Q, Antone J, Alsop E, Reiman R, Funk C, Bendl J, Dudley JT, Liang WS, Karr TL,\u00a0Roussos P<\/b>, Bennett DA, De Jager PL, Serrano GE, Beach TG, Keuren-Jensen KV, Mastroeni D, Reiman EM, Readhead BP. <\/span>bioRxiv. 2023 Oct 24. doi: 10.1101\/2023.10.20.563319. Preprint. <\/span>PMID:\u00a037961404<\/span><\/span><\/div>\n<\/div>\n
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Multi-omic profiling of the developing human cerebral cortex at the single-cell level.<\/strong><\/a><\/p>\n

Zhu K, Bendl J, Rahman S, Vicari JM, Coleman C, Clarence T, Latouche O,<\/strong> Tsankova NM, Li A, Brennand KJ, Lee D,<\/strong> Yuan GC, Fullard JF,<\/strong>\u00a0Roussos P. <\/b><\/span>Sci Adv. 2023 Oct 13. doi: 10.1126\/sciadv.adg3754. Epub 2023 Oct 12. <\/span>PMID:\u00a037824614<\/span><\/span><\/div>\n
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The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.<\/a><\/strong><\/p>\n

Girdhar K, Bendl J<\/strong>, Baumgartner A, Therrien K, Venkatesh S, Mathur D, Dong P, Rahman S,<\/strong> Kleopoulos SP<\/strong>, Misir R, Reach SM, Auluck PK, Marenco S, Lewis DA, Haroutunian V, Funk C, Voloudakis G, Hoffman GE, Fullard JF,<\/strong>\u00a0Roussos P. <\/b><\/span>Res Sq. 2023 Oct 2. doi: 10.21203\/rs.3.rs-3393581\/v1. Preprint. <\/span>PMID:\u00a037886514<\/span><\/span><\/div>\n
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Neuroimmune Mechanisms of Opioid Use Disorder and Recovery: Translatability to Human Studies, and Future Research Directions.<\/a><\/strong><\/p>\n

Butelman ER, Goldstein RZ, Nwaneshiudu CA, Girdhar K,<\/strong>\u00a0Roussos P<\/b>, Russo SJ, Alia-Klein N. <\/span>Neuroscience. 2023 Sep 15. doi: 10.1016\/j.neuroscience.2023.07.031. Epub 2023 Aug 9. <\/span>PMID:\u00a037562536<\/span><\/span><\/div>\n
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Multi-omic atlas of the parahippocampal gyrus in Alzheimer’s disease.<\/a><\/strong><\/p>\n

Coleman C<\/strong>, Wang M, Wang E, Micallef C<\/strong>, Shao Z, Vicari JM<\/strong>, Li Y, Yu K, Cai D, Peng J, Haroutunian V, Fullard JF, Bendl J<\/strong>, Zhang B,\u00a0Roussos P. <\/b><\/span>Sci Data. 2023 Sep 8. doi: 10.1038\/s41597-023-02507-2. <\/span>PMID:\u00a037684260<\/span><\/span><\/div>\n
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Genome-wide analysis of a model-derived binge eating disorder phenotype identifies risk loci and implicates iron metabolism.<\/a><\/strong><\/p>\n

Burstein D, Griffen TC, Therrien K, Bendl J, Venkatesh S, Dong P, Modabbernia A, Zeng B, Mathur D, Hoffman G, Sysko R, Hildebrandt T, Voloudakis G,\u00a0Roussos P. <\/b><\/span>Nat Genet. 2023 Sep. doi: 10.1038\/s41588-023-01464-1. Epub 2023 Aug 7. <\/span>PMID:\u00a037550530<\/span><\/span><\/div>\n
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The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina.<\/a><\/strong><\/p>\n

Pruvost M, Patzig J, Yattah C, Selcen I, Hernandez M, Park HJ, Moyon S, Liu S, Morioka MS, Shopland L, Al-Dalahmah O, Bendl J, Fullard JF,\u00a0Roussos P<\/b>, Goldman J, He Y, Dupree JL, Casaccia P.<\/span>Cell Rep. 2023 Aug 29. doi: 10.1016\/j.celrep.2023.112848. Epub 2023 Jul 28. <\/span>PMID:\u00a037515770<\/span><\/span><\/p>\n

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Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent\u00a0NRXN1<\/em>\u00a0and\u00a0ABCB11<\/em>\u00a0disruptions.<\/a><\/strong><\/p>\n

Maury EA, Sherman MA, Genovese G, Gilgenast TG, Kamath T, Burris SJ, Rajarajan P, Flaherty E, Akbarian S, Chess A, McCarroll SA, Loh PR, Phillips-Cremins JE, Brennand KJ, Macosko EZ, Walters JTR, O’Donovan M, Sullivan P; Psychiatric Genomic Consortium Schizophrenia and CNV workgroup<\/strong>; Brain Somatic Mosaicism Network; Sebat J, Lee EA, Walsh CA.<\/span>Cell Genom. 2023 Jul 6. doi: 10.1016\/j.xgen.2023.100356. eCollection 2023 Aug 9. <\/span>PMID:\u00a037601975<\/span><\/span><\/div>\n
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Genome-wide methylomic regulation of multiscale gene networks in Alzheimer’s disease.<\/a><\/strong><\/p>\n

Wang E, Wang M, Guo L, Fullard JF, Micallef C, Bendl J,<\/strong> Song WM, Ming C, Huang Y, Li Y, Yu K, Peng J, Bennett DA, De Jager PL,\u00a0Roussos P<\/b>, Haroutunian V, Zhang B. <\/span>Alzheimers Dement. 2023 Aug 19. doi: 10.1002\/alz.12969. Epub 2023 Feb 22. <\/span>PMID:\u00a036811307<\/span><\/span><\/div>\n
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Dopaminoceptive D1 and D2 neurons in ventral hippocampus arbitrate approach and avoidance in anxiety.<\/a><\/strong><\/p>\n

Godino A, Salery M, Minier-Toribio AM, Patel V, Fullard JF<\/strong>, Parise EM, Martinez-Rivera FJ, Morel C,\u00a0Roussos P<\/b>, Blitzer RD, Nestler EJ. <\/span>bioRxiv. 2023 Jul 28. doi: 10.1101\/2023.07.25.550554. Preprint. <\/span>PMID:\u00a037546856<\/span><\/span><\/div>\n
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Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis.<\/a><\/strong><\/p>\n

Kiss MG, Mindur JE, Yates AG, Lee D, Fullard JF,<\/strong> Anzai A, Poller WC, Christie KA, Iwamoto Y, Roudko V, Downey J, Chan CT, Huynh P, Janssen H, Ntranos A, Hoffmann JD, Jacob W, Goswami S, Singh S, Leppert D, Kuhle J, Kim-Schulze S, Nahrendorf M, Kleinstiver BP, Probert F,\u00a0Roussos P<\/b>, Swirski FK, McAlpine CS. <\/span>Immunity. 2023 Jul 11. doi: 10.1016\/j.immuni.2023.04.013. Epub 2023 May 8. <\/span>PMID:\u00a037160117<\/span><\/span><\/div>\n
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Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.<\/a><\/strong><\/p>\n

Als TD, Kurki MI, Grove J, Voloudakis G<\/strong>, Therrien K, Tasanko E, Nielsen TT, Naamanka J, Veerapen K, Levey DF, Bendl J<\/strong>, Bybjerg-Grauholm J, Zeng B<\/strong>, Demontis D, Rosengren A, Athanasiadis G, B\u00e6kved-Hansen M, Qvist P, Bragi Walters G, Thorgeirsson T, Stef\u00e1nsson H, Musliner KL, Rajagopal VM, Farajzadeh L, Thirstrup J, Vilhj\u00e1lmsson BJ, McGrath JJ, Mattheisen M, Meier S, Agerbo E, Stef\u00e1nsson K, Nordentoft M, Werge T, Hougaard DM, Mortensen PB, Stein MB, Gelernter J, Hovatta I,\u00a0Roussos P<\/b>, Daly MJ, Mors O, Palotie A, B\u00f8rglum AD. <\/span>Nat Med. 2023 Jul 29. doi: 10.1038\/s41591-023-02352-1. Epub 2023 Jul 18. <\/span>PMID:\u00a037464041<\/span><\/span><\/div>\n
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Diversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program.<\/a><\/strong><\/p>\n

Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, Ho YL, Kim Y, Heise DA, Guare L, Panickan VA, Garcon H, Linares F, Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner DC, Sangar R, Murray M, Wang X, Dochtermann DR, Devineni P, Shi Y, Nandi TN, Assimes TL, Brunette CA, Carroll RJ, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar SK, Joseph J, Kember R, Kranzler H, Levey D, Luoh SW, Merritt VC, Overstreet C, Deak JD, Grant SFA, Polimanti R,\u00a0Roussos P<\/b>, Sun YV, Venkatesh S, Voloudakis G<\/strong>, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao PS, O’Donnell CJ, Muralidhar S, Moser J, Casas JP, Bick AG, Zhou W, Cai T, Voight BF, Cho K, Gaziano MJ, Madduri RK, Damrauer SM, Liao KP. <\/span>medRxiv. Jun 29 2023. doi: 10.1101\/2023.06.28.23291975. Preprint. <\/span>PMID:\u00a037425708<\/span><\/span><\/div>\n
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Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation.<\/a><\/strong><\/p>\n

Alldred MJ, Pidikiti H, Heguy A,\u00a0Roussos P<\/b>, Ginsberg SD.<\/span>FASEB J. 2023 Jun. doi: 10.1096\/fj.202202111RR. <\/span>PMID:\u00a037191946<\/span><\/span><\/div>\n
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Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.<\/a><\/strong><\/p>\n

Hsu YH, Pintacuda G, Liu R, Nacu E, Kim A, Tsafou K, Petrossian N, Crotty W, Suh JM, Riseman J, Martin JM, Biagini JC, Mena D, Ching JKT, Malolepsza E, Li T, Singh T, Ge T, Egri SB, Tanenbaum B, Stanclift CR, Apffel AM; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>; Stanley Global Asia Initiatives; Carr SA, Schenone M, Jaffe J, Fornelos N, Huang H, Eggan KC, Lage K. <\/span>iScience. 2023 Apr 18. doi: 10.1016\/j.isci.2023.106701. eCollection 2023 May 19. <\/span>PMID:\u00a037207277<\/span><\/span><\/div>\n
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ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex.<\/a><\/strong><\/p>\n

Fulton SL, Bendl J<\/strong>, Gameiro-Ros I, Fullard JF<\/strong>, Al-Kachak A, Lepack AE, Stewart AF, Singh S, Poller WC, Bastle RM, Hauberg ME, Fakira AK, Chen M, Cuttoli RD, Cathomas F, Ramakrishnan A, Gleason K, Shen L, Tamminga CA, Milosevic A, Russo SJ, Swirski F, Blitzer RD, Slesinger PA,\u00a0Roussos P<\/b>, Maze I. <\/span>bioRxiv. 2023 May 4 2023. doi: 10.1101\/2023.05.04.539425. Preprint. <\/span>PMID:\u00a037205394<\/span><\/span><\/div>\n
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Applications of artificial intelligence-machine learning for detection of stress: a critical overview.<\/a><\/strong><\/p>\n

Mentis AA, Lee D,\u00a0<\/strong>Roussos P. <\/b><\/span>Mol Psychiatry. 2023 Apr 5. doi: 10.1038\/s41380-023-02047-6. Online ahead of print. <\/span>PMID:\u00a037020048<\/span><\/span><\/div>\n
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Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet.<\/a><\/strong><\/p>\n

Hoffman GE, Lee D, Bendl J, Fnu P<\/strong>, Hong A, Casey C<\/strong>, Alvia M, Shao Z, Argyriou S, Therrien K, Venkatesh S, Voloudakis G, <\/strong>Haroutunian V, Fullard JF<\/strong>,\u00a0Roussos P. <\/b><\/span>bioRxiv. Mar 20 2023. doi: 10.1101\/2023.03.17.533005. Preprint. <\/span>PMID:\u00a036993704<\/span><\/span><\/div>\n
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Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data.<\/a><\/strong><\/p>\n

Dai R, Chu T, Zhang M, Wang X, Jourdon A, Wu F, Mariani J, Vaccarino FM, Lee D, Fullard JF, Hoffman GE<\/strong>,\u00a0Roussos P<\/b>, Wang Y, Wang X,<\/strong> Pinto D, Wang SH, Zhang C; PsychENCODE consortium; Chen C, Liu C. <\/span>bioRxiv. Mar 15 2023. doi: 10.1101\/2023.03.13.532468. Preprint. <\/span>PMID:\u00a036993743<\/span><\/span><\/div>\n
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Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases.<\/a><\/strong><\/p>\n

Zeng B, Bendl J<\/strong>, Deng C, Lee D,<\/strong> Misir R, Reach SM, Kleopoulos SP, Auluck P, Marenco S, Lewis DA, Haroutunian V, Ahituv N, Fullard JF, Hoffman GE,<\/strong>\u00a0Roussos P. <\/b><\/span>bioRxiv. Mar 2 2023. doi: 10.1101\/2023.03.02.530826. Preprint. <\/span>PMID:\u00a037090548<\/span><\/span><\/div>\n
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Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations.<\/a><\/strong><\/p>\n

Liu D, Meyer D, Fennessy B, Feng C, Cheng E, Johnson JS, Park YJ, Rieder MK, Ascolillo S, de Pins A, Dobbyn A, Lebovitch D, Moya E, Nguyen TH, Wilkins L, Hassan A; Psychiatric Genomics Consortium Phase 3 Targeted Sequencing of Schizophrenia Study Team; Burdick KE, Buxbaum JD, Domenici E, Frangou S, Hartmann AM, Laurent-Levinson C, Malhotra D, Pato CN, Pato MT, Ressler K,\u00a0Roussos P<\/b>, Rujescu D, Arango C, Bertolino A, Blasi G, Bocchio-Chiavetto L, Campion D, Carr V, Fullerton JM, Gennarelli M, Gonz\u00e1lez-Pe\u00f1as J, Levinson DF, Mowry B, Nimgaokar VL, Pergola G, Rampino A, Cervilla JA, Rivera M, Schwab SG, Wildenauer DB, Daly M, Neale B, Singh T, O’Donovan MC, Owen MJ, Walters JT, Ayub M, Malhotra AK, Lencz T, Sullivan PF, Sklar P, Stahl EA, Huckins LM, Charney AW. <\/span>Nat Genet. 2023 Mar doi: 10.1038\/s41588-023-01305-1. Epub 2023 Mar 13. <\/span>PMID:\u00a036914870<\/span><\/span><\/div>\n
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African ancestry GWAS of dementia in a large military cohort identifies significant risk loci.<\/a><\/strong><\/p>\n

Sherva R, Zhang R, Sahelijo N, Jun G, Anglin T, Chanfreau C, Cho K, Fonda JR, Gaziano JM, Harrington KM, Ho YL, Kremen WS, Litkowski E, Lynch J, Neale Z,\u00a0Roussos P<\/b>, Marra D, Mez J, Miller MW, Salat DH, Tsuang D, Wolf E, Zeng Q, Panizzon MS, Merritt VC, Farrer LA, Hauger RL, Logue MW. <\/span>Mol Psychiatry. 2023 Mar 28 doi: 10.1038\/s41380-022-01890-3. Epub 2022 Dec 22 <\/span>PMID:\u00a036543923<\/span><\/span><\/div>\n
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Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.<\/a><\/strong><\/p>\n

Demontis D, Walters GB, Athanasiadis G, Walters R, Therrien K<\/strong>, Nielsen TT, Farajzadeh L, Voloudakis G, Bendl J, Zeng B<\/strong>, Zhang W, Grove J, Als TD, Duan J, Satterstrom FK, Bybjerg-Grauholm J, B\u00e6kved-Hansen M, Gudmundsson OO, Magnusson SH, Baldursson G, Davidsdottir K, Haraldsdottir GS, Agerbo E, Hoffman GE, Dalsgaard S, Martin J, Ribas\u00e9s M, Boomsma DI, Soler Artigas M, Roth Mota N, Howrigan D, Medland SE, Zayats T, Rajagopal VM; ADHD Working Group of the Psychiatric Genomics Consortium; iPSYCH-Broad Consortium; Nordentoft M, Mors O, Hougaard DM, Mortensen PB, Daly MJ, Faraone SV, Stefansson H,\u00a0Roussos P<\/b>, Franke B, Werge T, Neale BM, Stefansson K, B\u00f8rglum AD. <\/span>Nat Genet. 2023 Feb. doi: 10.1038\/s41588-022-01285-8. Epub 2023 Jan 26 <\/span>PMID:\u00a036702997<\/span><\/span><\/div>\n
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Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review.<\/a><\/strong><\/p>\n

Hoffman GE<\/strong>, Jaffe AE, Gandal MJ, Collado-Torres L, Sieberts SK, Devlin B, Geschwind DH, Weinberger DR,\u00a0Roussos P. <\/b><\/span>Mol Psychiatry. 2023 Feb 28 doi: 10.1038\/s41380-022-01781-7. Epub 2022 Sep 19.<\/span>PMID:\u00a036123423<\/span><\/span><\/div>\n
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Detecting and Adjusting for Hidden Biases due to Phenotype Misclassification in Genome-Wide Association Studies.<\/a><\/strong><\/p>\n

Burstein D, Hoffman G, Mathur D, Venkatesh S, Therrien K,<\/strong> Fanous AH, Bigdeli TB, Harvey PD,\u00a0Roussos P<\/b>, Voloudakis G<\/strong>. <\/span>medRxiv. Jan 18 2023. doi: 10.1101\/2023.01.17.23284670. Preprint. <\/span>PMID:\u00a036711948<\/span><\/span><\/div>\n
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Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity.<\/a><\/strong><\/p>\n

Rajagopal VM, Ganna A, Coleman JRI, Allegrini A, Voloudakis G, Grove J, Als TD, Horsdal HT, Petersen L, Appadurai V, Schork A, Buil A, Bulik CM, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Hougaard DM, Mors O, Nordentoft M, Werge T; iPSYCH-Broad Consortium; Mortensen PB, Breen G,\u00a0Roussos P<\/b>, Plomin R, Agerbo E, B\u00f8rglum AD, Demontis D. <\/span>Sci Rep. 2023 Jan 9. doi: 10.1038\/s41598-022-26845-0.<\/span>PMID:\u00a036624241<\/span><\/span><\/div>\n
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Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae.<\/a><\/strong><\/p>\n

Thompson RC, Simons NW, Wilkins L, Cheng E, Del Valle DM, Hoffman GE, Cervia C, Fennessy B, Mouskas K, Francoeur NJ, Johnson JS, Lepow L, Le Berichel J, Chang C, Beckmann AG, Wang YC, Nie K, Zaki N, Tuballes K, Barcessat V, Cedillo MA, Yuan D, Huckins L,\u00a0Roussos P<\/b>, Marron TU; Mount Sinai COVID-19 Biobank Team; Glicksberg BS, Nadkarni G, Heath JR, Gonzalez-Kozlova E, Boyman O, Kim-Schulze S, Sebra R, Merad M, Gnjatic S, Schadt EE, Charney AW, Beckmann ND. <\/span>Nat Med. 2023 Jan 29. doi: 10.1038\/s41591-022-02107-4. Epub 2022 Dec 8. <\/span>PMID:\u00a036482101<\/span><\/span><\/div>\n
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[\/et_pb_toggle][et_pb_toggle title=”2022″ closed_toggle_background_color=”#eaeaea” icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2022″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ border_radii=”on|6px|6px|6px|6px” border_width_all=”0.5px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.<\/strong><\/a><\/p>\n

Carcamo-Orive I, Hoffman GE<\/strong>, Cundiff P, Beckmann ND, D’Souza SL, Knowles JW, Patel A, Hendry C, Papatsenko D, Abbasi F, Reaven GM, Whalen S, Lee P, Shahbazi M, Henrion MYR, Zhu K, Wang S,\u00a0Roussos P<\/b>, Schadt EE, Pandey G, Chang R, Quertermous T, Lemischka I.<\/span>Cell Stem Cell. 2022 Oct 6;29(10):1505. doi: 10.1016\/j.stem.2022.08.011.<\/span>PMID:\u00a036206733<\/span><\/span><\/p>\n

The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease.<\/strong><\/a><\/p>\n

Bendl J<\/strong>, Hauberg ME, Girdhar K<\/strong>, Im E, Vicari JM, Rahman S,<\/strong> Fernando MB, Townsley KG, Dong P<\/strong>, Misir R, Kleopoulos SP<\/strong>, Reach SM, Apontes P, Zeng<\/strong> B<\/strong>, Zhang W, Voloudakis G<\/strong>, Brennand KJ, Nixon RA, Haroutunian V, Hoffman GE, Fullard JF<\/strong>,\u00a0Roussos P.<\/b><\/span>Nat Neurosci. 2022 Oct;25(10):1366-1378. doi: 10.1038\/s41593-022-01166-7. Epub 2022 Sep 28.<\/span>PMID:\u00a036171428<\/span><\/span><\/p>\n

Population-level variation in enhancer expression identifies disease mechanisms in the human brain.<\/strong><\/a><\/p>\n

Dong P, Hoffman GE,<\/strong> Apontes P, Bendl J, Rahman S<\/strong>, Fernando MB, Zeng B<\/strong>, Vicari JM,<\/strong> Zhang W, Girdhar K<\/strong>, Townsley KG, Misir R; CommonMind Consortium, Brennand KJ, Haroutunian V, Voloudakis G<\/strong>, Fullard JF<\/strong>,\u00a0Roussos P.<\/b><\/span>Nat Genet. 2022 Oct;54(10):1493-1503. doi: 10.1038\/s41588-022-01170-4. Epub 2022 Sep 26.<\/span>PMID:\u00a036163279<\/span><\/span><\/p>\n

Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups.<\/strong><\/a><\/p>\n

Mattheisen M, Grove J, Als TD, Martin J, Voloudakis G<\/strong>, Meier S, Demontis D, Bendl J,<\/strong> Walters R, Carey CE, Rosengren A, Strom NI, Hauberg ME, Zeng B<\/strong>, Hoffman G<\/strong>, Zhang W, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Agerbo E, Cormand B, Nordentoft M, Werge T, Mors O, Hougaard DM, Buxbaum JD, Faraone SV, Franke B, Dalsgaard S, Mortensen PB, Robinson EB,\u00a0Roussos P<\/b>, Neale BM, Daly MJ, B\u00f8rglum AD.<\/span>Nat Genet. 2022 Oct;54(10):1470-1478. doi: 10.1038\/s41588-022-01171-3. Epub 2022 Sep 26.<\/span>PMID:\u00a036163277<\/span><\/span><\/p>\n

Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review.<\/strong><\/a><\/p>\n

Hoffman GE<\/strong>, Jaffe AE, Gandal MJ, Collado-Torres L, Sieberts SK, Devlin B, Geschwind DH, Weinberger DR,\u00a0Roussos P. <\/b><\/span>Mol Psychiatry. 2022 Sep 19. doi: 10.1038\/s41380-022-01781-7. Online ahead of print.<\/span>PMID:\u00a036123423<\/span><\/span><\/p>\n

Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia, Bipolar Disorder, and Depression Among Adults in the US Veterans Affairs Health Care System.<\/strong><\/a><\/p>\n

Bigdeli TB, Voloudakis G<\/strong>, Barr PB, Gorman BR, Genovese G, Peterson RE, Burstein DE<\/strong>, Velicu VI, Li Y, Gupta R, Mattheisen M, Tomasi S, Rajeevan N, Sayward F, Radhakrishnan K, Natarajan S, Malhotra AK, Shi Y, Zhao H, Kosten TR, Concato J, O’Leary TJ, Przygodzki R, Gleason T, Pyarajan S, Brophy M, Huang GD, Muralidhar S, Gaziano JM, Aslan M, Fanous AH, Harvey PD,\u00a0Roussos P<\/b>; Cooperative Studies Program (CSP) #572 and Million Veteran Program (MVP).<\/span>JAMA Psychiatry. 2022 Sep 14:e222742. doi: 10.1001\/jamapsychiatry.2022.2742. Online ahead of print.<\/span>PMID:\u00a036103194<\/span><\/span><\/p>\n

A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility.<\/strong><\/a><\/p>\n

Voloudakis G, Vicari JM, Venkatesh S, Hoffman GE<\/strong>, Dobrindt K, Zhang W, Beckmann ND, Higgins CA, Argyriou S, Jiang S, Hoagland D, Gao L, Corvelo A, Cho K, Lee KM, Bian J, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Lynch JA, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative, Brennand KJ, Fullard JF<\/strong>,\u00a0Roussos P.<\/b><\/span>NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038\/s41525-022-00324-x.<\/span>PMID:\u00a036064543<\/span><\/span><\/p>\n

Genetics of the human microglia regulome refines Alzheimer’s disease risk loci.<\/strong><\/a><\/p>\n

Kosoy R, Fullard JF, Zeng B, Bendl J, Dong P, Rahman S, Kleopoulos SP, Shao Z, Girdhar K,<\/strong> Humphrey J, de Paiva Lopes K, Charney AW, Kopell BH, Raj T, Bennett D, Kellner CP, Haroutunian V, Hoffman GE,<\/strong>\u00a0Roussos P.<\/b><\/span>Nat Genet. 2022 Aug;54(8):1145-1154. doi: 10.1038\/s41588-022-01149-1. Epub 2022 Aug 5.<\/span>PMID:\u00a035931864<\/span><\/span><\/p>\n

The Neuroepigenome: Implications of Chemical and Physical Modifications of Genomic DNA in Schizophrenia.<\/strong><\/a><\/p>\n

Girdhar K, Rahman S, Dong P, Fullard JF,<\/strong>\u00a0Roussos P.<\/b><\/span>Biol Psychiatry. 2022 Sep 15;92(6):443-449. doi: 10.1016\/j.biopsych.2022.04.018. Epub 2022 May 10.<\/span>PMID:\u00a035750513<\/span><\/span><\/p>\n

Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development.<\/strong><\/a><\/p>\n

Liu D, Zinski A, Mishra A, Noh H, Park GH, Qin Y, Olorife O, Park JM, Abani CP, Park JS, Fung J, Sawaqed F, Coyle JT, Stahl E, Bendl J, Fullard JF,<\/strong>\u00a0Roussos P<\/b>, Zhang X, Stanton PK, Yin C, Huang W, Kim HY, Won H, Cho JH, Chung S. Mol Psychiatry. 2022 Jun 14. doi: 10.1038\/s41380-022-01654-z. Online ahead of print.<\/span>PMID:\u00a035701597<\/span><\/span><\/p>\n

Mapping genomic loci implicates genes and synaptic biology in schizophrenia.<\/strong><\/a><\/p>\n

Trubetskoy V, Pardi\u00f1as AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G<\/strong>, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fa\u00f1an\u00e1s L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodr\u00edguez P, Godard S, Goldstein JI, Gonz\u00e1lez Pe\u00f1as J, Gonz\u00e1lez-Pinto A, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, G\u00fcl\u00f6ks\u00fcz S, Gur RE, Gur RC, Guti\u00e9rrez B, Hahn E, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Juli\u00e0 A, K\u00e4hler AK, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Kebir O, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kraft J, Kubo M, Ku\u010dinskas V, Ku\u010dinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lencer R, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, L\u00f6nnqvist J, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M Jr, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Mallet J, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mitjans M, Molden E, Molina E, Molto MD, Mondelli V, Moreno C, Morley CP, Muntan\u00e9 G, Murphy KC, Myin-Germeys I, Nenadi\u0107 I, Nestadt G, Nikitina-Zake L, Noto C, Nuechterlein KH, O’Brien NL, O’Neill FA, Oh SY, Olincy A, Ota VK, Pantelis C, Papadimitriou GN, Parellada M, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pfuhlmann B, Pietil\u00e4inen O, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Roth J, Rothermundt M, Rutten BPF, Saker-Delye S, Salomaa V, Sanjuan J, Santoro ML, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Skarabis N, Slominsky P, So HC, Sobell JL, S\u00f6derman E, Stain HJ, Steen NE, Steixner-Kumar AA, St\u00f6gmann E, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Ta TMT, Takahashi A, Terao C, Thibaut F, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, \u00dc\u00e7ok A, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Walter H, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atba\u015fo\u011flu EC, Ayub M, Benner C, Bertolino A, Black DW, Bray NJ, Breen G, Buccola NG, Byerley WF, Chen WJ, Cloninger CR, Crespo-Facorro B, Donohoe G, Freedman R, Galletly C, Gandal MJ, Gennarelli M, Hougaard DM, Hwu HG, Jablensky AV, McCarroll SA, Moran JL, Mors O, Mortensen PB, M\u00fcller-Myhsok B, Neil AL, Nordentoft M, Pato MT, Petryshen TL, Pirinen M, Pulver AE, Schulze TG, Silverman JM, Smoller JW, Stahl EA, Tsuang DW, Vilella E, Wang SH, Xu S; Indonesia Schizophrenia Consortium; PsychENCODE; Psychosis Endophenotypes International Consortium; SynGO Consortium, Adolfsson R, Arango C, Baune BT, Belangero SI, B\u00f8rglum AD, Braff D, Bramon E, Buxbaum JD, Campion D, Cervilla JA, Cichon S, Collier DA, Corvin A, Curtis D, Forti MD, Domenici E, Ehrenreich H, Escott-Price V, Esko T, Fanous AH, Gareeva A, Gawlik M, Gejman PV, Gill M, Glatt SJ, Golimbet V, Hong KS, Hultman CM, Hyman SE, Iwata N, J\u00f6nsson EG, Kahn RS, Kennedy JL, Khusnutdinova E, Kirov G, Knowles JA, Krebs MO, Laurent-Levinson C, Lee J, Lencz T, Levinson DF, Li QS, Liu J, Malhotra AK, Malhotra D, McIntosh A, McQuillin A, Menezes PR, Morgan VA, Morris DW, Mowry BJ, Murray RM, Nimgaonkar V, N\u00f6then MM, Ophoff RA, Paciga SA, Palotie A, Pato CN, Qin S, Rietschel M, Riley BP, Rivera M, Rujescu D, Saka MC, Sanders AR, Schwab SG, Serretti A, Sham PC, Shi Y, St Clair D, Stef\u00e1nsson H, Stefansson K, Tsuang MT, van Os J, Vawter MP, Weinberger DR, Werge T, Wildenauer DB, Yu X, Yue W, Holmans PA, Pocklington AJ,\u00a0Roussos P<\/b>, Vassos E, Verhage M, Visscher PM, Yang J, Posthuma D, Andreassen OA, Kendler KS, Owen MJ, Wray NR, Daly MJ, Huang H, Neale BM, Sullivan PF, Ripke S, Walters JTR, O’Donovan MC; Schizophrenia Working Group of the Psychiatric Genomics Consortium.<\/span>Nature. 2022 Apr;604(7906):502-508. doi: 10.1038\/s41586-022-04434-5. Epub 2022 Apr 8.<\/span>PMID:\u00a035396580<\/span><\/span><\/p>\n

A complete temporal transcription factor series in the fly visual system.<\/strong><\/a><\/p>\n

Konstantinides N, Holguera I, Rossi AM, Escobar A, Dudragne L, Chen YC, Tran TN, Mart\u00ednez Jaimes AM, \u00d6zel MN, Simon F, Shao Z<\/strong>, Tsankova NM, Fullard JF,<\/strong> Walldorf U,\u00a0Roussos P<\/b>, Desplan C.<\/span>Nature. 2022 Apr;604(7905):316-322. doi: 10.1038\/s41586-022-04564-w. Epub 2022 Apr 6.<\/span>PMID:\u00a035388222<\/span><\/span><\/p>\n

Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains.<\/strong><\/a><\/p>\n

Girdhar K, Hoffman GE, Bendl J, Rahman S, Dong P,<\/strong> Liao W, Hauberg ME, Sloofman L, Brown L, Devillers O, Kassim BS, Wiseman JR, Park R, Zharovsky E, Jacobov R, Flatow E, Kozlenkov A, Gilgenast T, Johnson JS, Couto L, Peters MA, Phillips-Cremins JE, Hahn CG, Gur RE, Tamminga CA, Lewis DA, Haroutunian V; PsychENCODE Consortium, Dracheva S, Lipska BK, Marenco S, Kundakovic M, Fullard JF<\/strong>, Jiang Y,\u00a0Roussos P<\/b>, Akbarian S.<\/span>Nat Neurosci. 2022 Apr;25(4):474-483. doi: 10.1038\/s41593-022-01032-6. Epub 2022 Mar 24.<\/span>PMID:\u00a035332326<\/span><\/span><\/p>\n

Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia.<\/strong><\/a><\/p>\n

Zazhytska M, Kodra A, Hoagland DA, Frere J, Fullard JF<\/strong>, Shayya H, McArthur NG, Moeller R, Uhl S, Omer AD, Gottesman ME, Firestein S, Gong Q, Canoll PD, Goldman JE,\u00a0Roussos P<\/b>, tenOever BR, Jonathan B Overdevest, Lomvardas S.<\/span>Cell. 2022 Mar 17;185(6):1052-1064.e12. doi: 10.1016\/j.cell.2022.01.024. Epub 2022 Feb 2.<\/span>PMID:\u00a035180380<\/span><\/span><\/p>\n

Altered gene expression and PTSD symptom dimensions in World Trade Center responders.<\/strong><\/a><\/p>\n

Marchese S, Cancelmo L, Diab O, Cahn L, Aaronson C, Daskalakis NP, Schaffer J, Horn SR, Johnson JS, Schechter C, Desarnaud F, Bierer LM, Makotkine I, Flory JD, Crane M, Moline JM, Udasin IG, Harrison DJ,\u00a0Roussos P<\/b>, Charney DS, Koenen KC, Southwick SM, Yehuda R, Pietrzak RH, Huckins LM, Feder A.<\/span>Mol Psychiatry. 2022 Apr;27(4):2225-2246. doi: 10.1038\/s41380-022-01457-2. Epub 2022 Feb 17.<\/span>PMID:\u00a035177824<\/span><\/span><\/p>\n

Transcriptome-wide association study in UK Biobank Europeans identifies associations with blood cell traits<\/strong>.<\/a><\/p>\n

Rowland B, Venkatesh S, Tardaguila M, Wen J, Rosen JD, Tapia AL, Sun Q, Graff M, Vuckovic D, Lettre G, Sankaran VG, Voloudakis G,<\/strong>\u00a0Roussos P<\/b>, Huffman JE, Reiner AP, Soranzo N, Raffield LM, Li Y.<\/span>Hum Mol Genet. 2022 Jul 21;31(14):2333-2347. doi: 10.1093\/hmg\/ddac011.<\/span>PMID:\u00a035138379<\/span><\/span><\/p>\n

Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits.<\/strong><\/a><\/p>\n

Zeng B, Bendl J<\/strong>, Kosoy R, Fullard JF, Hoffman GE,<\/strong>\u00a0Roussos P. <\/b><\/span>Nat Genet. 2022 Feb;54(2):161-169. doi: 10.1038\/s41588-021-00987-9. Epub 2022 Jan 20.<\/span>PMID:\u00a035058635<\/span><\/span><\/p>\n

A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning.<\/strong><\/a><\/p>\n

Hafez AK, Zimmerman AJ, Papageorgiou G, Chandrasekaran J, Amoah SK, Lin R, Lozano E, Pierotti C, Dell’Orco M, Hartley BJ, Alural B, Lalonde J, Esposito JM, Berretta S, Squassina A, Chillotti C, Voloudakis G<\/strong>, Shao Z, Fullard JF<\/strong>, Brennand KJ, Turecki G, Roussos P<\/strong>,\u00a0Perlis RH, Haggarty SJ, Perrone-Bizzozero N, Brigman JL, Mellios N.
Cell Rep. 2022 Jan 18;38(3):110282. doi: 10.1016\/j.celrep.2021.110282.
PMID: 35045295<\/p>\n

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.<\/strong><\/a><\/p>\n

Pardi\u00f1as AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P, Wu JQ, Andreassen OA, Kowalec K, Sullivan PF, Murray RM, Owen MJ, MacCabe JH, O’Donovan MC, Walters JTR; Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances (STRATA) Consortium and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC)<\/strong>, Ajnakina O, Alameda L, Barnes TRE, Berardi D, Bonora E, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D’Andrea G, Demjaha A, Do KQ, Doody GA, Eap CB, Ferchiou A, Di Forti M, Guidi L, Homman L, Jenni R, Joyce EM, Kassoumeri L, Khadimallah I, Lastrina O, Muratori R, Noyan H, O’Neill FA, Pignon B, Restellini R, Richard JR, Sch\u00fcrhoff F, \u0160paniel F, Sz\u00f6ke A, Tarricone I, Tortelli A, \u00dc\u00e7ok A, V\u00e1zquez-Bourgon J.<\/span>JAMA Psychiatry. 2022 Mar 1;79(3):260-269. doi: 10.1001\/jamapsychiatry.2021.3799.<\/span>PMID:\u00a035019943<\/span><\/span><\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2021″ closed_toggle_background_color=”#eaeaea” icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2021″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ border_radii=”on|6px|6px|6px|6px” border_width_all=”0.5px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.<\/strong><\/a><\/p>\n

Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, Hafferty JD, Hishimoto A, Kim M, Okazaki S, Otsuka I, Ripke S, Ware EB, Bergen AW, Berrettini WH, Bohus M, Brandt H, Chang X, Chen WJ, Chen HC, Crawford S, Crow S, DiBlasi E, Duriez P, Fern\u00e1ndez-Aranda F, Fichter MM, Gallinger S, Glatt SJ, Gorwood P, Guo Y, Hakonarson H, Halmi KA, Hwu HG, Jain S, Jamain S, Jim\u00e9nez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Klump KL, Li D, Liao SC, Lieb K, Lilenfeld L, Liu CM, Magistretti PJ, Marshall CR, Mitchell JE, Monson ET, Myers RM, Pinto D, Powers A, Ramoz N, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Strober M, Thornton LM, Treasure J, Tsuang MT, Witt SH, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Air TM, Alda M, Alfredsson L, Andreassen OA, Anjorin A, Appadurai V, Soler Artigas M, Van der Auwera S, Azevedo MH, Bass N, Bau CHD, Baune BT, Bellivier F, Berger K, Biernacka JM, Bigdeli TB, Binder EB, Boehnke M, Boks MP, Bosch R, Braff DL, Bryant R, Budde M, Byrne EM, Cahn W, Casas M, Castelao E, Cervilla JA, Chaumette B, Cichon S, Corvin A, Craddock N, Craig D, Degenhardt F, Djurovic S, Edenberg HJ, Fanous AH, Foo JC, Forstner AJ, Frye M, Fullerton JM, Gatt JM, Gejman PV, Giegling I, Grabe HJ, Green MJ, Grevet EH, Grigoroiu-Serbanescu M, Gutierrez B, Guzman-Parra J, Hamilton SP, Hamshere ML, Hartmann A, Hauser J, Heilmann-Heimbach S, Hoffmann P, Ising M, Jones I, Jones LA, Jonsson L, Kahn RS, Kelsoe JR, Kendler KS, Kloiber S, Koenen KC, Kogevinas M, Konte B, Krebs MO, Land\u00e9n M, Lawrence J, Leboyer M, Lee PH, Levinson DF, Liao C, Lissowska J, Lucae S, Mayoral F, McElroy SL, McGrath P, McGuffin P, McQuillin A, Medland SE, Mehta D, Melle I, Milaneschi Y, Mitchell PB, Molina E, Morken G, Mortensen PB, M\u00fcller-Myhsok B, Nievergelt C, Nimgaonkar V, N\u00f6then MM, O’Donovan MC, Ophoff RA, Owen MJ, Pato C, Pato MT, Penninx BWJH, Pimm J, Pistis G, Potash JB, Power RA, Preisig M, Quested D, Ramos-Quiroga JA, Reif A, Ribas\u00e9s M, Richarte V, Rietschel M, Rivera M, Roberts A, Roberts G, Rouleau GA, Rovaris DL, Rujescu D, S\u00e1nchez-Mora C, Sanders AR, Schofield PR, Schulze TG, Scott LJ, Serretti A, Shi J, Shyn SI, Sirignano L, Sklar P, Smeland OB, Smoller JW, Sonuga-Barke EJS, Spalletta G, Strauss JS, \u015awi\u0105tkowska B, Trzaskowski M, Turecki G, Vilar-Rib\u00f3 L, Vincent JB, V\u00f6lzke H, Walters JTR, Shannon Weickert C, Weickert TW, Weissman MM, Williams LM, Wray NR, Zai CC, Ashley-Koch AE, Beckham JC, Hauser ER, Hauser MA, Kimbrel NA, Lindquist JH, McMahon B, Oslin DW, Qin X; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>; Eating Disorders Working Group of the Psychiatric Genomics Consortium; German Borderline Genomics Consortium; MVP Suicide Exemplar Workgroup; VA Million Veteran Program, Agerbo E, B\u00f8rglum AD, Breen G, Erlangsen A, Esko T, Gelernter J, Hougaard DM, Kessler RC, Kranzler HR, Li QS, Martin NG, McIntosh AM, Mors O, Nordentoft M, Olsen CM, Porteous D, Ursano RJ, Wasserman D, Werge T, Whiteman DC, Bulik CM, Coon H, Demontis D, Docherty AR, Kuo PH, Lewis CM, Mann JJ, Renter\u00eda ME, Smith DJ, Stahl EA, Stein MB, Streit F, Willour V, Ruderfer DM.<\/span>Biol Psychiatry. 2022 Feb 1;91(3):313-327. doi: 10.1016\/j.biopsych.2021.05.029. Epub 2021 Sep 9.<\/span>PMID:\u00a034861974<\/span><\/span><\/p>\n

Correction to: Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer’s Disease.<\/a><\/strong><\/p>\n

Alldred MJ, Penikalapati SC, Lee SH, Heguy A,\u00a0Roussos P<\/b>, Ginsberg SD.<\/span>Mol Neurobiol. 2022 Feb;59(2):1345-1346. doi: 10.1007\/s12035-021-02647-9.<\/span>PMID:\u00a034837629<\/span><\/span><\/p>\n

Engagement of vascular early response genes typifies mild cognitive impairment.<\/a><\/strong><\/p>\n

Katsel P, Fam P, Tan W, Khan S, Gama-Sosa M, De Gasperi R,\u00a0Roussos P<\/b>, Robinson A, Cooper I, Schnaider-Beeri M, Haroutunian V.<\/span>Alzheimers Dement. 2022 Jul;18(7):1357-1369. doi: 10.1002\/alz.12481. Epub 2021 Nov 10.<\/span>PMID:\u00a034758195<\/span><\/span><\/p>\n

Use of the PsycheMERGE Network to Investigate the Association Between Depression Polygenic Scores and White Blood Cell Count.<\/a><\/strong><\/p>\n

Sealock JM, Lee YH, Moscati A, Venkatesh S<\/strong>, Voloudakis G<\/strong>, Straub P, Singh K, Feng YA, Ge T,\u00a0Roussos P<\/b>, Smoller JW, Chen G, Davis LK. JAMA Psychiatry. 2021 Dec 1;78(12):1365-1374. doi: 10.1001\/jamapsychiatry.2021.2959.<\/span>PMID:\u00a034668925<\/span><\/span><\/span><\/p>\n

Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.<\/a><\/strong>
Cirnaru MD, Song S, Tshilenge KT, Corwin C, Mleczko J, Galicia Aguirre C, Benlhabib H, Bendl J, Apontes P, Fullard J<\/strong>, Creus-Muncunill J, Reyahi A, Nik AM, Carlsson P,\u00a0Roussos P<\/strong>, Mooney SD, Ellerby LM, Ehrlich ME. Elife. 2021 Oct 5;10:e65979. doi: 10.7554\/eLife.65979.<\/em>PMID:\u00a034609283<\/p>\n

Author Correction: Brain Cell Type Specific Gene Expression and Co-expression Network Architectures.<\/a><\/strong>
McKenzie AT, Wang M, Hauberg ME, Fullard JF<\/strong>, Kozlenkov A, Keenan A, Hurd YL, Dracheva S, Casaccia P,\u00a0Roussos P<\/strong>, Zhang B. Sci Rep. 2021 Sep 24;11(1):19430. doi: 10.1038\/s41598-021-97284-6.<\/em>PMID:\u00a034561470<\/p>\n

Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children.<\/a><\/strong>
Beckmann ND, Comella PH, Cheng E, Lepow L, Beckmann AG, Tyler SR, Mouskas K, Simons NW, Hoffman GE<\/strong>, Francoeur NJ, Del Valle DM, Kang G, Do A, Moya E, Wilkins L, Le Berichel J, Chang C, Marvin R, Calorossi S, Lansky A, Walker L, Yi N, Yu A, Chung J, Hartnett M, Eaton M, Hatem S, Jamal H, Akyatan A, Tabachnikova A, Liharska LE, Cotter L, Fennessy B, Vaid A, Barturen G, Shah H, Wang YC, Sridhar SH, Soto J, Bose S, Madrid K, Ellis E, Merzier E, Vlachos K, Fishman N, Tin M, Smith M, Xie H, Patel M, Nie K, Argueta K, Harris J, Karekar N, Batchelor C, Lacunza J, Yishak M, Tuballes K, Scott I, Kumar A, Jaladanki S, Agashe C, Thompson R, Clark E, Losic B, Peters L; Mount Sinai COVID-19 Biobank Team,\u00a0Roussos P<\/strong>, Zhu J, Wang W, Kasarskis A, Glicksberg BS, Nadkarni G, Bogunovic D, Elaiho C, Gangadharan S, Ofori-Amanfo G, Alesso-Carra K, Onel K, Wilson KM, Argmann C, Bunyavanich S, Alarc\u00f3n-Riquelme ME, Marron TU, Rahman A, Kim-Schulze S, Gnjatic S, Gelb BD, Merad M, Sebra R, Schadt EE, Charney AW. Nat Commun. 2021 Aug 11;12(1):4854. doi: 10.1038\/s41467-021-24981-1.<\/em>PMID:\u00a034381049<\/p>\n

Association between genes regulating neural pathways for quantitative traits of speech and language disorders.<\/a><\/strong>
Benchek P, Igo RP Jr, Voss-Hoynes H, Wren Y, Miller G, Truitt B, Zhang W, Osterman M, Freebairn L, Tag J, Taylor HG, Chan ER,\u00a0Roussos P<\/strong>, Lewis B, Stein CM, Iyengar SK. NPJ Genom Med. 2021 Jul 27;6(1):64. doi: 10.1038\/s41525-021-00225-5.<\/em>PMID:\u00a034315907<\/p>\n

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.<\/a><\/strong>
Ni G, Zeng J, Revez JA, Wang Y, Zheng Z, Ge T, Restuadi R, Kiewa J, Nyholt DR, Coleman JRI, Smoller JW; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>, Yang J, Visscher PM, Wray NR. Biol Psychiatry. 2021 Nov 1;90(9):611-620. doi: 10.1016\/j.biopsych.2021.04.018. Epub 2021 May 4.<\/em>PMID:\u00a034304866<\/p>\n

Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19. <\/a><\/strong>
Fullard JF, Lee HC, Voloudakis G<\/strong>, Suo S, Javidfar B, Shao Z<\/strong>, Peter C, Zhang W, Jiang S, Corvelo A, Wargnier H, Woodoff-Leith E, Purohit DP, Ahuja S, Tsankova NM, Jette N, Hoffman GE<\/strong>, Akbarian S, Fowkes M, Crary JF, Yuan GC, Roussos P.<\/strong> Genome Med. 2021 Jul 19;13(1):118. doi: 10.1186\/s13073-021-00933-8.<\/em> PMID: 34281603<\/p>\n

Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer’s Disease.<\/a><\/strong>
Alldred MJ, Penikalapati SC, Lee SH, Heguy A,\u00a0Roussos P<\/strong>, Ginsberg SD. Mol Neurobiol. 2021 Jul 14. doi: 10.1007\/s12035-021-02453-3. Online ahead of print.<\/em>PMID:<\/em>\u00a0<\/em>34263425<\/em><\/p>\n

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders.<\/strong><\/a>
Hu B, Won H, Mah W, Park RB, Kassim B, Spiess K, Kozlenkov A, Crowley CA, Pochareddy S; PsychENCODE Consortium<\/strong>, Li Y, Dracheva S, Sestan N, Akbarian S, Geschwind DH. Nat Commun. 2021 Jun 25;12(1):3968. doi: 10.1038\/s41467-021-24243-0.PMID:\u00a034172755<\/em><\/p>\n

Sex Differences in the Human Brain Transcriptome of Cases With Schizophrenia.<\/strong><\/a>
Hoffman GE<\/strong>, Ma Y,<\/strong> Montgomery KS, Bendl J<\/strong>, Jaiswal MK, Kozlenkov A, Peters MA, Dracheva S, Fullard JF<\/strong>, Chess A, Devlin B, Sieberts SK,\u00a0Roussos P. <\/strong>Biol Psychiatry. 2021 Mar 25:S0006-3223(21)01180-X. doi: 10.1016\/j.biopsych.2021.03.020. Online ahead of print.PMID:\u00a034154796<\/em><\/p>\n

Common genetic variation influencing human white matter microstructure.<\/a><\/strong>
Zhao B, Li T, Yang Y, Wang X, Luo T, Shan Y, Zhu Z, Xiong D, Hauberg ME, Bendl J, Fullard JF<\/strong>,\u00a0Roussos P<\/strong>, Li Y, Stein JL, Zhu H. Science. 2021 Jun 18;372(6548):eabf3736. doi: 10.1126\/science.abf3736.PMID:\u00a034140357<\/em><\/p>\n

IL10RB as a key regulator of COVID-19 host susceptibility and severity.<\/strong><\/a>
Voloudakis G, Hoffman G, Venkatesh S<\/strong>, Lee KM, Dobrindt K, Vicari JM, Zhang W<\/strong>, Beckmann ND, Jiang S, Hoagland D, Bian J, Gao L, Corvelo A, Cho K, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative, Brennand KJ, Lynch JA, Fullard JF<\/strong>,\u00a0Roussos P. <\/strong>medRxiv. 2021 Jun 2:2021.05.31.21254851. doi: 10.1101\/2021.05.31.21254851. Preprint.PMID:\u00a034100031<\/em>
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Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.<\/strong><\/a>
Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, J\u00f6nsson EG, Palotie A, Ehrenreich H, Begemann M, Steixner-Kumar A, Sham PC, Iwata N, Weinberger DR, Gejman PV, Sanders AR, Buxbaum JD, Rujescu D, Giegling I, Konte B, Hartmann AM, Bramon E, Murray RM, Pato MT, Lee J, Melle I, Molden E, Ophoff RA, McQuillin A, Bass NJ, Adolfsson R, Malhotra AK; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>, Martin NG, Fullerton JM, Mitchell PB, Schofield PR, Forstner AJ, Degenhardt F, Schaupp S, Comes AL, Kogevinas M, Guzman-Parra J, Reif A, Streit F, Sirignano L, Cichon S, Grigoroiu-Serbanescu M, Hauser J, Lissowska J, Mayoral F, M\u00fcller-Myhsok B, \u015awi\u0105tkowska B, Schulze TG, N\u00f6then MM, Rietschel M, Kelsoe J, Leboyer M, Jamain S, Etain B, Bellivier F, Vincent JB, Alda M, O’Donovan C, Cervantes P, Biernacka JM, Frye M, McElroy SL, Scott LJ, Stahl EA, Land\u00e9n M, Hamshere ML, Smeland OB, Djurovic S, Vaaler AE, Andreassen OA; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>, Baune BT, Air T, Preisig M, Uher R, Levinson DF, Weissman MM, Potash JB, Shi J, Knowles JA, Perlis RH, Lucae S, Boomsma DI, Penninx BWJH, Hottenga JJ, de Geus EJC, Willemsen G, Milaneschi Y, Tiemeier H, Grabe HJ, Teumer A, Van der Auwera S, V\u00f6lker U, Hamilton SP, Magnusson PKE, Viktorin A, Mehta D, Mullins N, Adams MJ, Breen G, McIntosh AM, Lewis CM; Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium<\/strong>; iPSYCH, Hougaard DM, Nordentoft M, Mors O, Mortensen PB, Werge T, Als TD, B\u00f8rglum AD, Petryshen TL, Smoller JW, Goldstein JM. Biol Psychiatry. 2021 Mar 23:S0006-3223(21)01139-2. doi: 10.1016\/j.biopsych.2021.02.972. Online ahead of print.PMID:\u00a034099189<\/em><\/p>\n

scGRNom: a computational pipeline of integrative multi-omics analyses for predicting cell-type disease genes and regulatory networks.<\/strong><\/a>
Jin T, Rehani P, Ying M, Huang J, Liu S,\u00a0Roussos P<\/strong>, Wang D. Genome Med. 2021 May 27;13(1):95. doi: 10.1186\/s13073-021-00908-9.PMID:\u00a034044854<\/em>
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Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics.<\/strong><\/a>
Lam M, Chen CY, Ge T, Xia Y, Hill DW, Trampush JW, Yu J, Knowles E, Davies G, Stahl EA, Huckins L, Liewald DC, Djurovic S, Melle I, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AM,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Koltai DC, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Smyrnis N, Bilder RM, Freimer NB, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Huang H, Liu C, Malhotra AK, Lencz T. Neuropsychopharmacology. 2021 May 25. doi: 10.1038\/s41386-021-01023-4. Online ahead of print.PMID:\u00a034035472<\/em><\/p>\n

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.<\/a><\/strong>
Mullins N, Forstner AJ, O’Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, B\u00f8rte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HH, Abramova L, Adorjan K, Agerbo E, Al Eissa M, Albani D, Alliey-Rodriguez N, Anjorin A, Antilla V, Antoniou A, Awasthi S, Baek JH, B\u00e6kvad-Hansen M, Bass N, Bauer M, Beins EC, Bergen SE, Birner A, B\u00f8cker Pedersen C, B\u00f8en E, Boks MP, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cairns M, Casas M, Cervantes P, Clarke TK, Cruceanu C, Cuellar-Barboza A, Cunningham J, Curtis D, Czerski PM, Dale AM, Dalkner N, David FS, Degenhardt F, Djurovic S, Dobbyn AL, Douzenis A, Elvs\u00e5shagen T, Escott-Price V, Ferrier IN, Fiorentino A, Foroud TM, Forty L, Frank J, Frei O, Freimer NB, Fris\u00e9n L, Gade K, Garnham J, Gelernter J, Gi\u00f8rtz Pedersen M, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha K, Haraldsson M, Hautzinger M, Heilbronner U, Hellgren D, Herms S, Hoffmann P, Holmans PA, Huckins L, Jamain S, Johnson JS, Kalman JL, Kamatani Y, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koromina M, Kranz TM, Kranzler HR, Kubo M, Kupka R, Kushner SA, Lavebratt C, Lawrence J, Leber M, Lee HJ, Lee PH, Levy SE, Lewis C, Liao C, Lucae S, Lundberg M, MacIntyre DJ, Magnusson SH, Maier W, Maihofer A, Malaspina D, Maratou E, Martinsson L, Mattheisen M, McCarroll SA, McGregor NW, McGuffin P, McKay JD, Medeiros H, Medland SE, Millischer V, Montgomery GW, Moran JL, Morris DW, M\u00fchleisen TW, O’Brien N, O’Donovan C, Olde Loohuis LM, Oruc L, Papiol S, Pardi\u00f1as AF, Perry A, Pfennig A, Porichi E, Potash JB, Quested D, Raj T, Rapaport MH, DePaulo JR, Regeer EJ, Rice JP, Rivas F, Rivera M, Roth J,\u00a0Roussos P<\/strong>, Ruderfer DM, S\u00e1nchez-Mora C, Schulte EC, Senner F, Sharp S, Shilling PD, Sigurdsson E, Sirignano L, Slaney C, Smeland OB, Smith DJ, Sobell JL, S\u00f8holm Hansen C, Soler Artigas M, Spijker AT, Stein DJ, Strauss JS, \u015awi\u0105tkowska B, Terao C, Thorgeirsson TE, Toma C, Tooney P, Tsermpini EE, Vawter MP, Vedder H, Walters JTR, Witt SH, Xi S, Xu W, Yang JMK, Young AH, Young H, Zandi PP, Zhou H, Zillich L; HUNT All-In Psychiatry, Adolfsson R, Agartz I, Alda M, Alfredsson L, Babadjanova G, Backlund L, Baune BT, Bellivier F, Bengesser S, Berrettini WH, Blackwood DHR, Boehnke M, B\u00f8rglum AD, Breen G, Carr VJ, Catts S, Corvin A, Craddock N, Dannlowski U, Dikeos D, Esko T, Etain B, Ferentinos P, Frye M, Fullerton JM, Gawlik M, Gershon ES, Goes FS, Green MJ, Grigoroiu-Serbanescu M, Hauser J, Henskens F, Hillert J, Hong KS, Hougaard DM, Hultman CM, Hveem K, Iwata N, Jablensky AV, Jones I, Jones LA, Kahn RS, Kelsoe JR, Kirov G, Land\u00e9n M, Leboyer M, Lewis CM, Li QS, Lissowska J, Lochner C, Loughland C, Martin NG, Mathews CA, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Michie P, Milani L, Mitchell PB, Morken G, Mors O, Mortensen PB, Mowry B, M\u00fcller-Myhsok B, Myers RM, Neale BM, Nievergelt CM, Nordentoft M, N\u00f6then MM, O’Donovan MC, Oedegaard KJ, Olsson T, Owen MJ, Paciga SA, Pantelis C, Pato C, Pato MT, Patrinos GP, Perlis RH, Posthuma D, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribas\u00e9s M, Rietschel M, Ripke S, Rouleau GA, Saito T, Schall U, Schalling M, Schofield PR, Schulze TG, Scott LJ, Scott RJ, Serretti A, Shannon Weickert C, Smoller JW, Stefansson H, Stefansson K, Stordal E, Streit F, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Waldman ID, Weickert TW, Werge T, Wray NR, Zwart JA, Biernacka JM, Nurnberger JI, Cichon S, Edenberg HJ, Stahl EA, McQuillin A, Di Florio A, Ophoff RA, Andreassen OA. Nat Genet. 2021 Jun;53(6):817-829. doi: 10.1038\/s41588-021-00857-4. Epub 2021 May 17.PMID:\u00a034002096<\/em><\/p>\n

Sex Differences in Molecular Rhythms in the Human Cortex.<\/strong><\/a>
Logan RW, Xue X, Ketchesin KD, Hoffman G,\u00a0Roussos P<\/strong>, Tseng G, McClung CA, Seney ML. Biol Psychiatry. 2021 Mar 8:S0006-3223(21)01110-0. doi: 10.1016\/j.biopsych.2021.03.005. Online ahead of print.PMID:\u00a033934884<\/em><\/p>\n

Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.<\/a><\/strong>
Novikova G, Kapoor M, Tcw J, Abud EM, Efthymiou AG, Chen SX, Cheng H, Fullard JF, Bendl J,<\/strong> Liu Y,\u00a0Roussos P<\/strong>, Bj\u00f6rkegren JL, Liu Y, Poon WW, Hao K, Marcora E, Goate AM. Nat Commun. 2021 Mar 12;12(1):1610. doi: 10.1038\/s41467-021-21823-y.PMID:\u00a033712570<\/em>
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Disruption of nuclear architecture as a cause of COVID-19 induced anosmia.<\/strong><\/a>
Zazhytska M, Kodra A, Hoagland DA, Fullard JF<\/strong>, Shayya H, Omer A, Firestein S, Gong Q, Canoll PD, Goldman JE,\u00a0Roussos P<\/strong>, tenOever BR, Overdevest JB, Lomvardas S. bioRxiv. 2021 Feb 9:2021.02.09.430314. doi: 10.1101\/2021.02.09.430314. Preprint.PMID: 33594368<\/em><\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2020″ closed_toggle_background_color=”#eaeaea” icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2020″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ border_radii=”on|6px|6px|6px|6px” border_width_all=”0.5px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons.<\/strong><\/a>
Hauberg ME<\/strong>, Creus-Muncunill J, Bendl<\/strong> J, Kozlenkov A, Zeng B,<\/strong> Corwin C, Chowdhury S, Kranz H, Hurd YL, Wegner M, B\u00f8rglum AD, Dracheva S, Ehrlich ME, Fullard JF<\/strong>,\u00a0Roussos P. <\/strong>Nat Commun. 2020 Nov 4;11(1):5581. doi: 10.1038\/s41467-020-19319-2.PMID:\u00a033149216<\/em>\u00a0Free PMC article.<\/strong><\/p>\n

Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network.<\/strong><\/a>
Yazdani A, Mendez-Giraldez R, Yazdani A, Kosorok MR,\u00a0Roussos P. <\/strong>BMC Bioinformatics. 2020 Oct 21;21(1):469. doi: 10.1186\/s12859-020-03753-6.PMID:\u00a033087039<\/em>\u00a0Free PMC article.<\/strong><\/p>\n

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.<\/strong><\/a>
Sieberts SK, Perumal TM, Carrasquillo MM, Allen M, Reddy JS, Hoffman GE, Dang KK, Calley J, Ebert PJ, Eddy J, Wang X, Greenwood AK, Mostafavi S; CommonMind Consortium (CMC)<\/strong>; The AMP-AD Consortium, Omberg L, Peters MA, Logsdon BA, De Jager PL, Ertekin-Taner N, Mangravite LM. Sci Data. 2020 Oct 12;7(1):340. doi: 10.1038\/s41597-020-00642-8.PMID: 33046718<\/em>\u00a0Free PMC article.<\/strong><\/p>\n

Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder.<\/strong><\/a>
Egervari G, Akpoyibo D, Rahman T, Fullard JF,<\/strong> Callens JE, Landry JA, Ly A, Zhou X, Warren N, Hauberg ME<\/strong>, Hoffman G<\/strong>, Ellis R, Ferland JN, Miller ML, Keller E, Zhang B,\u00a0Roussos P<\/strong>, Hurd YL. Nat Commun. 2020 Sep 14;11(1):4634. doi: 10.1038\/s41467-020-18114-3.PMID: 32929078<\/em>
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dream: Powerful differential expression analysis for repeated measures designs.<\/strong><\/a>
Hoffman GE<\/strong>, Roussos P. <\/strong>Bioinformatics. 2020 Jul 30:btaa687. doi: 10.1093\/bioinformatics\/btaa687. Online ahead of print.PMID:\u00a032730587<\/em><\/p>\n

Functional annotation of rare structural variation in the human brain.<\/strong><\/a>
Han L, Zhao X, Benton ML, Perumal T, Collins RL, Hoffman GE<\/strong>, Johnson JS, Sloofman L, Wang HZ, Stone MR; CommonMind Consortium<\/strong>, Brennand KJ, Brand H, Sieberts SK, Marenco S, Peters MA, Lipska BK,\u00a0Roussos P<\/strong>, Capra JA, Talkowski M, Ruderfer DM. Nat Commun. 2020 Jun 12;11(1):2990. doi: 10.1038\/s41467-020-16736-1.PMID: 32533064<\/em>\u00a0Free PMC article.<\/strong><\/p>\n

Complement genes contribute sex-biased vulnerability in diverse disorders.<\/a><\/strong>
Kamitaki N, Sekar A, Handsaker RE, de Rivera H, Tooley K, Morris DL, Taylor KE, Whelan CW, Tombleson P, Loohuis LMO; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Boehnke M, Kimberly RP, Kaufman KM, Harley JB, Langefeld CD, Seidman CE, Pato MT, Pato CN, Ophoff RA, Graham RR, Criswell LA, Vyse TJ, McCarroll SA. Nature. 2020 Jun;582(7813):577-581. doi: 10.1038\/s41586-020-2277-x. Epub 2020 May 11.PMID: 32499649<\/em><\/p>\n

Big Data Analysis and Genetic Liability to Neuropsychiatric Disease.<\/strong><\/a>
Roussos P. <\/strong>Adv Exp Med Biol. 2020;1194:455. doi: 10.1007\/978-3-030-32622-7_43.PMID:\u00a032468561<\/em><\/p>\n

A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons.<\/strong><\/a>
Espeso-Gil S, Halene T, Bendl J, Kassim B, Ben Hutta G, Iskhakova M, Shokrian N, Auluck P, Javidfar B, Rajarajan P, Chandrasekaran S, Peter CJ, Cote A, Birnbaum R, Liao W, Borrman T, Wiseman J, Bell A, Bannon MJ,\u00a0Roussos P<\/strong>, Crary JF, Weng Z, Marenco S, Lipska B, Tsankova NM, Huckins L, Jiang Y, Akbarian S. Genome Med. 2020 Feb 19;12(1):19. doi: 10.1186\/s13073-020-0715-x.PMID: 32075678<\/em>
<\/strong><\/p>\n

Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer’s disease.<\/strong><\/a>
Woo YJ,\u00a0Roussos P<\/strong>, Haroutunian V, Katsel P, Gandy S, Schadt EE, Zhu J; Alzheimer Disease Neuroimaging Initiative (ADNI).BMC Med. 2020 Feb 6;18(1):23. doi: 10.1186\/s12916-019-1488-1.PMID:\u00a032024511<\/em>
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decorate: differential epigenetic correlation test.<\/strong><\/a>
Hoffman GE, Bendl J, Girdhar K<\/strong>, Roussos P. <\/strong>Bioinformatics. 2020 May 1;36(9):2856-2861. doi: 10.1093\/bioinformatics\/btaa067.PMID:\u00a032003784<\/em><\/p>\n

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.<\/strong><\/a>
Coleman JRI, Gaspar HA, Bryois J; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Breen G. Biol Psychiatry. 2020 Jul 15;88(2):169-184. doi: 10.1016\/j.biopsych.2019.10.015. Epub 2019 Nov 1.PMID: 31926635<\/em><\/p>\n

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.<\/strong><\/a>
Andlauer TFM, Guzman-Parra J, Streit F, Strohmaier J, Gonz\u00e1lez MJ, Gil Flores S, Cabaleiro Fabeiro FJ, Del R\u00edo Noriega F, Perez FP, Haro Gonz\u00e1lez J, Orozco Diaz G, de Diego-Otero Y, Moreno-K\u00fcstner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Treutlein J, Witt SH, Cichon S, Kogevinas M; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Rivas F, Mayoral F, M\u00fcller-Myhsok B, Forstner AJ, N\u00f6then MM, Rietschel M. Mol Psychiatry. 2019 Nov 11. doi: 10.1038\/s41380-019-0558-2. Online ahead of print<\/em>.PMID: 31712721<\/p>\n

CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.<\/strong><\/a>
Hoffman GE, Bendl J, Voloudakis G<\/strong>, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K<\/strong>, Song L, Fullard JF<\/strong>, Kramer R, Hahn CG, Gur R, Marenco S, Lipska BK, Lewis DA, Haroutunian V, Hemby S, Sullivan P, Akbarian S, Chess A, Buxbaum JD, Crawford GE, Domenici E, Devlin B, Sieberts SK, Peters MA, Roussos P<\/strong>.
Sci Data. 2019 Sep 24;6(1):180. doi: 10.1038\/s41597-019-0183-6.<\/em> PMID: 31551426<\/p>\n

Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification.<\/strong><\/a>
Hoffman GE, Bendl J, Girdhar K<\/strong>, Schadt EE, Roussos P<\/strong>.
Nucleic Acids Res. 2019 Sep 23. pii: gkz808. doi: 10.1093\/nar\/gkz808. [Epub ahead of print]<\/em> PMID: 31544924<\/p>\n

A polygenic resilience score moderates the genetic risk for schizophrenia.<\/strong><\/a>
Hess JL, Tylee DS, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>; Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), B\u00f8rglum AD, Als TD, Grove J, Werge T, Mortensen PB, Mors O, Nordentoft M, Hougaard DM, Byberg-Grauholm J, B\u00e6kvad-Hansen M, Greenwood TA, Tsuang MT, Curtis D, Steinberg S, Sigurdsson E, Stef\u00e1nsson H, Stef\u00e1nsson K, Edenberg HJ, Holmans P, Faraone SV, Glatt SJ.
Mol Psychiatry. 2019 Sep 6. doi: 10.1038\/s41380-019-0463-8. [Epub ahead of print]<\/em> PMID: 31492941<\/p>\n

Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia.<\/strong><\/a>
Breen MS, Dobbyn A, Li Q, Roussos P<\/strong>, Hoffman GE<\/strong>, Stahl E, Chess A, Sklar P, Li JB, Devlin B, Buxbaum JD; CommonMind Consortium.
Nat Neurosci. 2019 Sep;22(9):1402-1412. doi: 10.1038\/s41593-019-0463-7. Epub 2019 Aug 27.<\/em> PMID:31455887<\/p>\n

Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.<\/strong><\/a>
Zhang W, Voloudakis G, Rajagopal VM,<\/strong> Readhead B, Dudley JT, Schadt EE, Bj\u00f6rkegren JLM, Kim Y, Fullard JF, Hoffman GE<\/strong>, Roussos P<\/strong>.
Nat Commun. 2019 Aug 23;10(1):3834. doi: 10.1038\/s41467-019-11874-7<\/em>. PMID:31444360<\/p>\n

Genetic Variation in Long-Range Enhancers.<\/a><\/strong>
Fullard JF, Rahman S<\/strong>, Roussos P<\/strong>.
Curr Top Behav Neurosci. 2019 Aug 9. doi: 10.1007\/7854_2019_110. [Epub ahead of print<\/em>] PMID:31396896<\/p>\n

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.<\/strong><\/a>
Lam M, Hill WD, Trampush JW, Yu J, Knowles E, Davies G, Stahl E, Huckins L, Liewald DC, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AM, Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Am J Hum Genet. 2019 Aug 1;105(2):334-350. doi: 10.1016\/j.ajhg.2019.06.012.<\/em>PMID:31374203<\/p>\n

Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM<\/strong>, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O’Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Jun;51(6):1068. doi: 10.1038\/s41588-019-0435-6.<\/em> PMID:31086353<\/p>\n

Genome-wide association study identifies 30 loci associated with bipolar disorder.<\/strong><\/a>
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, B\u00e6kvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, B\u00f8en E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvs\u00e5shagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Fris\u00e9n L, Gade K, Gage D, Garnham J, Giambartolomei C<\/strong>, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS<\/strong>, Jur\u00e9us A, Kandaswamy R, Karlsson R, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koller AC, Kupka R, Lavebratt C, Lawrence J, Lawson WB, Leber M, Lee PH, Levy SE, Li JZ, Liu C, Lucae S, Maaser A, MacIntyre DJ, Mahon PB, Maier W, Martinsson L, McCarroll S, McGuffin P, McInnis MG, McKay JD, Medeiros H, Medland SE, Meng F, Milani L, Montgomery GW, Morris DW, M\u00fchleisen TW, Mullins N, Nguyen H, Nievergelt CM, Adolfsson AN, Nwulia EA, O’Donovan C, Loohuis LMO, Ori APS, Oruc L, \u00d6sby U, Perlis RH, Perry A, Pfennig A, Potash JB, Purcell SM, Regeer EJ, Reif A, Reinbold CS, Rice JP, Rivas F, Rivera M, Roussos P<\/strong>, Ruderfer DM, Ryu E, S\u00e1nchez-Mora C, Schatzberg AF, Scheftner WA, Schork NJ, Shannon Weickert C, Shehktman T, Shilling PD, Sigurdsson E, Slaney C, Smeland OB, Sobell JL, S\u00f8holm Hansen C, Spijker AT, St Clair D, Steffens M, Strauss JS, Streit F, Strohmaier J, Szelinger S, Thompson RC, Thorgeirsson TE, Treutlein J, Vedder H, Wang W, Watson SJ, Weickert TW, Witt SH, Xi S, Xu W, Young AH, Zandi P, Zhang P, Z\u00f6llner S; eQTLGen Consortium; BIOS Consortium, Adolfsson R, Agartz I, Alda M, Backlund L, Baune BT, Bellivier F, Berrettini WH, Biernacka JM, Blackwood DHR, Boehnke M, B\u00f8rglum AD, Corvin A, Craddock N, Daly MJ, Dannlowski U, Esko T, Etain B, Frye M, Fullerton JM, Gershon ES, Gill M, Goes F, Grigoroiu-Serbanescu M, Hauser J, Hougaard DM, Hultman CM, Jones I, Jones LA, Kahn RS, Kirov G, Land\u00e9n M, Leboyer M, Lewis CM, Li QS, Lissowska J, Martin NG, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Metspalu A, Mitchell PB, Morken G, Mors O, Mortensen PB, M\u00fcller-Myhsok B, Myers RM, Neale BM, Nimgaonkar V, Nordentoft M, N\u00f6then MM, O’Donovan MC, Oedegaard KJ, Owen MJ, Paciga SA, Pato C, Pato MT, Posthuma D, Ramos-Quiroga JA, Ribas\u00e9s M, Rietschel M, Rouleau GA, Schalling M, Schofield PR, Schulze TG, Serretti A, Smoller JW, Stefansson H, Stefansson K, Stordal E, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Werge T, Nurnberger JI, Wray NR, Di Florio A, Edenberg HJ, Cichon S, Ophoff RA, Scott LJ, Andreassen OA, Kelsoe J, Sklar P; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium.
Nat Genet. 2019 May;51(5):793-803. doi: 10.1038\/s41588-019-0397-8. Epub 2019 May 1<\/em>. PMID:31043756<\/p>\n

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.<\/a><\/strong>
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, B\u00f6hmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, K\u00e4h\u00f6nen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtim\u00e4ki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytik\u00e4inen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P<\/strong>, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumar\u00e9 A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, H\u00e4gg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, R\u00e4ikk\u00f6nen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.
Nat Commun. 2019 May 1;10(1):2068. doi: 10.1038\/s41467-019-10160-w.<\/em> PMID:31043617<\/p>\n

Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes.<\/strong><\/a>
Drange OK, Smeland OB, Shadrin AA, Finseth PI, Witoelar A, Frei O; Psychiatric Genomics Consortium Bipolar Disorder Working Group,<\/strong> Wang Y, Hassani S, Djurovic S, Dale AM, Andreassen OA.
Front Neurosci. 2019 Mar 13;13:220. doi: 10.3389\/fnins.2019.00220. eCollection 2019.<\/em> PMID:30930738<\/p>\n

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM<\/strong>, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O’Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Apr;51(4):659-674. doi: 10.1038\/s41588-019-0364-4. Epub 2019 Mar 25. Erratum in: Nat Genet. 2019 Jun;51(6):1068<\/a>.<\/em> \u00a0PMID:30911161<\/p>\n

Identification of common genetic risk variants for autism spectrum disorder.<\/strong><\/a>
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, N\u00e6rland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnstr\u00f6m K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos P<\/strong>, Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, B\u00f8rglum AD.
Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038\/s41588-019-0344-8. Epub 2019 Feb 25.<\/em> PMID:30804558<\/p>\n

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.<\/strong><\/a>
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O’Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Donohoe G, Gill M, Corvin A, Morris DW.
Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002\/ajmg.b.32716. Epub 2019 Feb 23.<\/em> PMID:30801977<\/p>\n

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V.
NPJ Schizophr. 2019 Jan 29;5(1):3. doi: 10.1038\/s41537-019-0071-2.<\/em> PMID:30696826<\/p>\n

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium<\/strong>; Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O’Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Mar 25. doi: 10.1038\/s41588-019-0364-4. [Epub ahead of print]<\/em> PMID:30911161<\/p>\n

Cell- and layer-specific transcriptomic strategy for characterizing the molecular phenotype of rat cortical neurons using laser capture microdissection and massively parallel RNA sequencing.<\/strong><\/a>
Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P,<\/strong> Shen L, Baxter MG, Hurd YL.
Mol Psychiatry. 2019 Apr;24(4):473. doi: 10.1038\/s41380-019-0390-8. No abstract available.<\/em>PMID:30899095<\/p>\n

Identification of common genetic risk variants for autism spectrum disorder.<\/strong><\/a>
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, N\u00e6rland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnstr\u00f6m K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos<\/strong> P,<\/strong> Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, B\u00f8rglum AD.
Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038\/s41588-019-0344-8. Epub 2019 Feb 25.<\/em> PMID:30804558<\/p>\n

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.<\/strong><\/a>
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O’Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Donohoe G, Gill M, Corvin A, Morris DW.
Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002\/ajmg.b.32716. Epub 2019 Feb 23<\/em>. PMID:30801977<\/p>\n

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V.
NPJ Schizophr. 2019 Jan 29;5(1):3. doi: 10.1038\/s41537-019-0071-2.<\/em> PMID: 30696826<\/p>\n

Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia.<\/strong><\/a>
Fullard JF<\/strong>, Charney AW, Voloudakis G<\/strong>, Uzilov AV, Haroutunian V, Roussos P<\/strong>.
Transl Psychiatry. 2019 Jan 17;9(1):21. doi: 10.1038\/s41398-018-0342-0.<\/em> PMID: 30655504<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2019″ closed_toggle_background_color=”#eaeaea” icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2019″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ border_radii=”on|6px|6px|6px|6px” border_width_all=”0.5px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.<\/strong><\/a>
Andlauer TFM, Guzman-Parra J, Streit F, Strohmaier J, Gonz\u00e1lez MJ, Gil Flores S, Cabaleiro Fabeiro FJ, Del R\u00edo Noriega F, Perez FP, Haro Gonz\u00e1lez J, Orozco Diaz G, de Diego-Otero Y, Moreno-K\u00fcstner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Treutlein J, Witt SH, Cichon S, Kogevinas M; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Rivas F, Mayoral F, M\u00fcller-Myhsok B, Forstner AJ, N\u00f6then MM, Rietschel M.Mol Psychiatry. 2019 Nov 11. doi: 10.1038\/s41380-019-0558-2. Online ahead of print.PMID:\u00a031712721<\/p>\n

CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.<\/strong><\/a>
Hoffman GE, Bendl J, Voloudakis G<\/strong>, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K<\/strong>, Song L, Fullard JF<\/strong>, Kramer R, Hahn CG, Gur R, Marenco S, Lipska BK, Lewis DA, Haroutunian V, Hemby S, Sullivan P, Akbarian S, Chess A, Buxbaum JD, Crawford GE, Domenici E, Devlin B, Sieberts SK, Peters MA, Roussos P<\/strong>.
Sci Data. 2019 Sep 24;6(1):180. doi: 10.1038\/s41597-019-0183-6.<\/em> PMID: 31551426<\/p>\n

Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification.<\/strong><\/a>
Hoffman GE, Bendl J, Girdhar K<\/strong>, Schadt EE, Roussos P<\/strong>.
Nucleic Acids Res. 2019 Sep 23. pii: gkz808. doi: 10.1093\/nar\/gkz808. [Epub ahead of print]<\/em> PMID: 31544924<\/p>\n

A polygenic resilience score moderates the genetic risk for schizophrenia.<\/strong><\/a>
Hess JL, Tylee DS, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>; Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), B\u00f8rglum AD, Als TD, Grove J, Werge T, Mortensen PB, Mors O, Nordentoft M, Hougaard DM, Byberg-Grauholm J, B\u00e6kvad-Hansen M, Greenwood TA, Tsuang MT, Curtis D, Steinberg S, Sigurdsson E, Stef\u00e1nsson H, Stef\u00e1nsson K, Edenberg HJ, Holmans P, Faraone SV, Glatt SJ.
Mol Psychiatry. 2019 Sep 6. doi: 10.1038\/s41380-019-0463-8. [Epub ahead of print]<\/em> PMID: 31492941<\/p>\n

Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia.<\/strong><\/a>
Breen MS, Dobbyn A, Li Q, Roussos P<\/strong>, Hoffman GE<\/strong>, Stahl E, Chess A, Sklar P, Li JB, Devlin B, Buxbaum JD; CommonMind Consortium.
Nat Neurosci. 2019 Sep;22(9):1402-1412. doi: 10.1038\/s41593-019-0463-7. Epub 2019 Aug 27.<\/em> PMID:31455887<\/p>\n

Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.<\/strong><\/a>
Zhang W, Voloudakis G, Rajagopal VM,<\/strong> Readhead B, Dudley JT, Schadt EE, Bj\u00f6rkegren JLM, Kim Y, Fullard JF, Hoffman GE<\/strong>, Roussos P<\/strong>.
Nat Commun. 2019 Aug 23;10(1):3834. doi: 10.1038\/s41467-019-11874-7<\/em>. PMID:31444360<\/p>\n

Genetic Variation in Long-Range Enhancers.<\/a>
Fullard JF, Rahman S<\/strong>, Roussos P<\/strong>.
Curr Top Behav Neurosci. 2019 Aug 9. doi: 10.1007\/7854_2019_110. [Epub ahead of print<\/em>] PMID:31396896<\/p>\n

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.<\/strong><\/a>
Lam M, Hill WD, Trampush JW, Yu J, Knowles E, Davies G, Stahl E, Huckins L, Liewald DC, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AM, Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Am J Hum Genet. 2019 Aug 1;105(2):334-350. doi: 10.1016\/j.ajhg.2019.06.012.<\/em>PMID:31374203<\/p>\n

Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM<\/strong>, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O’Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Jun;51(6):1068. doi: 10.1038\/s41588-019-0435-6.<\/em> PMID:31086353<\/p>\n

Genome-wide association study identifies 30 loci associated with bipolar disorder.<\/strong><\/a>
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, B\u00e6kvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, B\u00f8en E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvs\u00e5shagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Fris\u00e9n L, Gade K, Gage D, Garnham J, Giambartolomei C<\/strong>, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS<\/strong>, Jur\u00e9us A, Kandaswamy R, Karlsson R, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koller AC, Kupka R, Lavebratt C, Lawrence J, Lawson WB, Leber M, Lee PH, Levy SE, Li JZ, Liu C, Lucae S, Maaser A, MacIntyre DJ, Mahon PB, Maier W, Martinsson L, McCarroll S, McGuffin P, McInnis MG, McKay JD, Medeiros H, Medland SE, Meng F, Milani L, Montgomery GW, Morris DW, M\u00fchleisen TW, Mullins N, Nguyen H, Nievergelt CM, Adolfsson AN, Nwulia EA, O’Donovan C, Loohuis LMO, Ori APS, Oruc L, \u00d6sby U, Perlis RH, Perry A, Pfennig A, Potash JB, Purcell SM, Regeer EJ, Reif A, Reinbold CS, Rice JP, Rivas F, Rivera M, Roussos P<\/strong>, Ruderfer DM, Ryu E, S\u00e1nchez-Mora C, Schatzberg AF, Scheftner WA, Schork NJ, Shannon Weickert C, Shehktman T, Shilling PD, Sigurdsson E, Slaney C, Smeland OB, Sobell JL, S\u00f8holm Hansen C, Spijker AT, St Clair D, Steffens M, Strauss JS, Streit F, Strohmaier J, Szelinger S, Thompson RC, Thorgeirsson TE, Treutlein J, Vedder H, Wang W, Watson SJ, Weickert TW, Witt SH, Xi S, Xu W, Young AH, Zandi P, Zhang P, Z\u00f6llner S; eQTLGen Consortium; BIOS Consortium, Adolfsson R, Agartz I, Alda M, Backlund L, Baune BT, Bellivier F, Berrettini WH, Biernacka JM, Blackwood DHR, Boehnke M, B\u00f8rglum AD, Corvin A, Craddock N, Daly MJ, Dannlowski U, Esko T, Etain B, Frye M, Fullerton JM, Gershon ES, Gill M, Goes F, Grigoroiu-Serbanescu M, Hauser J, Hougaard DM, Hultman CM, Jones I, Jones LA, Kahn RS, Kirov G, Land\u00e9n M, Leboyer M, Lewis CM, Li QS, Lissowska J, Martin NG, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Metspalu A, Mitchell PB, Morken G, Mors O, Mortensen PB, M\u00fcller-Myhsok B, Myers RM, Neale BM, Nimgaonkar V, Nordentoft M, N\u00f6then MM, O’Donovan MC, Oedegaard KJ, Owen MJ, Paciga SA, Pato C, Pato MT, Posthuma D, Ramos-Quiroga JA, Ribas\u00e9s M, Rietschel M, Rouleau GA, Schalling M, Schofield PR, Schulze TG, Serretti A, Smoller JW, Stefansson H, Stefansson K, Stordal E, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Werge T, Nurnberger JI, Wray NR, Di Florio A, Edenberg HJ, Cichon S, Ophoff RA, Scott LJ, Andreassen OA, Kelsoe J, Sklar P; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium.
Nat Genet. 2019 May;51(5):793-803. doi: 10.1038\/s41588-019-0397-8. Epub 2019 May 1<\/em>. PMID:31043756<\/p>\n

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.<\/a><\/strong>
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, B\u00f6hmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, K\u00e4h\u00f6nen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtim\u00e4ki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytik\u00e4inen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P<\/strong>, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumar\u00e9 A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, H\u00e4gg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, R\u00e4ikk\u00f6nen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.
Nat Commun. 2019 May 1;10(1):2068. doi: 10.1038\/s41467-019-10160-w.<\/em> PMID:31043617<\/p>\n

Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes.<\/strong><\/a>
Drange OK, Smeland OB, Shadrin AA, Finseth PI, Witoelar A, Frei O; Psychiatric Genomics Consortium Bipolar Disorder Working Group,<\/strong> Wang Y, Hassani S, Djurovic S, Dale AM, Andreassen OA.
Front Neurosci. 2019 Mar 13;13:220. doi: 10.3389\/fnins.2019.00220. eCollection 2019.<\/em> PMID:30930738<\/p>\n

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM<\/strong>, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O’Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Apr;51(4):659-674. doi: 10.1038\/s41588-019-0364-4. Epub 2019 Mar 25. Erratum in: Nat Genet. 2019 Jun;51(6):1068<\/a>.<\/em> \u00a0PMID:30911161<\/p>\n

Identification of common genetic risk variants for autism spectrum disorder.<\/strong><\/a>
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, N\u00e6rland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnstr\u00f6m K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos P<\/strong>, Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, B\u00f8rglum AD.
Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038\/s41588-019-0344-8. Epub 2019 Feb 25.<\/em> PMID:30804558<\/p>\n

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.<\/strong><\/a>
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O’Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Donohoe G, Gill M, Corvin A, Morris DW.
Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002\/ajmg.b.32716. Epub 2019 Feb 23.<\/em> PMID:30801977<\/p>\n

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V.
NPJ Schizophr. 2019 Jan 29;5(1):3. doi: 10.1038\/s41537-019-0071-2.<\/em> PMID:30696826<\/p>\n

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium<\/strong>; Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O’Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Mar 25. doi: 10.1038\/s41588-019-0364-4. [Epub ahead of print]<\/em> PMID:30911161<\/p>\n

Cell- and layer-specific transcriptomic strategy for characterizing the molecular phenotype of rat cortical neurons using laser capture microdissection and massively parallel RNA sequencing.<\/strong><\/a>
Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P,<\/strong> Shen L, Baxter MG, Hurd YL.
Mol Psychiatry. 2019 Apr;24(4):473. doi: 10.1038\/s41380-019-0390-8. No abstract available.<\/em>PMID:30899095<\/p>\n

Identification of common genetic risk variants for autism spectrum disorder.<\/strong><\/a>
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, N\u00e6rland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnstr\u00f6m K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos<\/strong> P,<\/strong> Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, B\u00f8rglum AD.
Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038\/s41588-019-0344-8. Epub 2019 Feb 25.<\/em> PMID:30804558<\/p>\n

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.<\/strong><\/a>
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O’Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Donohoe G, Gill M, Corvin A, Morris DW.
Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002\/ajmg.b.32716. Epub 2019 Feb 23<\/em>. PMID:30801977<\/p>\n

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V.
NPJ Schizophr. 2019 Jan 29;5(1):3. doi: 10.1038\/s41537-019-0071-2.<\/em> PMID: 30696826<\/p>\n

Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia.<\/strong><\/a>
Fullard JF<\/strong>, Charney AW, Voloudakis G<\/strong>, Uzilov AV, Haroutunian V, Roussos P<\/strong>.
Transl Psychiatry. 2019 Jan 17;9(1):21. doi: 10.1038\/s41398-018-0342-0.<\/em> PMID: 30655504<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2018″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2018″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Biopsy During Minimally Invasive Intracerebral Hemorrhage Clot Evacuation.<\/strong><\/a>
Lieber AC, McNeill IT, Scaggiante J, Nistal DA, Fowkes M, Umphlett M, Pan J, Roussos P<\/strong>, Mobbs CV, Mocco J, Kellner CP.
World Neurosurg. 2018 Dec 24. pii: S1878-8750(18)32881-X. doi: 10.1016\/j.wneu.2018.12.058. [Epub ahead of print]<\/em> PMID: 30590212<\/p>\n

Comprehensive functional genomic resource and integrative model for the human brain.<\/strong><\/a>
Wang D, Liu S, Warrell J, Won H, Shi X, Navarro FCP, Clarke D, Gu M, Emani P, Yang YT, Xu M, Gandal MJ, Lou S, Zhang J, Park JJ, Yan C, Rhie SK, Manakongtreecheep K, Zhou H, Nathan A, Peters M, Mattei E, Fitzgerald D, Brunetti T, Moore J, Jiang Y, Girdhar K<\/strong>, Hoffman GE<\/strong>, Kalayci S, G\u00fcm\u00fc\u015f ZH, Crawford GE; PsychENCODE Consortium, Roussos P<\/strong>, Akbarian S, Jaffe AE, White KP, Weng Z, Sestan N, Geschwind DH, Knowles JA, Gerstein MB.
Science. 2018 Dec 14;362(6420). pii: eaat8464. doi: 10.1126\/science.aat8464.<\/em> PMID: 30545857<\/p>\n

Integrative functional genomic analysis of human brain development and neuropsychiatric risks.<\/strong><\/a>
Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, Choi J, Muchnik S, Xu X, Wang D, Lorente-Galdos B, Liu S, Giusti-Rodr\u00edguez P, Won H, de Leeuw CA, Pardi\u00f1as AF; BrainSpan Consortium; PsychENCODE Consortium<\/strong>; PsychENCODE Developmental Subgroup, Hu M, Jin F, Li Y, Owen MJ, O’Donovan MC, Walters JTR, Posthuma D, Levitt P, Weinberger DR, Hyde TM, Kleinman JE, Geschwind DH, Hawrylycz MJ, State MW, Sanders SJ, Sullivan PF, Gerstein MB, Lein ES, Knowles JA, Sestan N.
Science. 2018 Dec 14;362(6420). pii: eaat7615. doi: 10.1126\/science.aat7615.<\/em> PMID: 30545854<\/p>\n

Transcriptome and epigenome landscape of human cortical development modeled in organoids.<\/strong><\/a>
Amiri A, Coppola G, Scuderi S, Wu F, Roychowdhury T, Liu F, Pochareddy S, Shin Y, Safi A, Song L, Zhu Y, Sousa AMM; PsychENCODE Consortium<\/strong>, Gerstein M, Crawford GE, Sestan N, Abyzov A, Vaccarino FM.
Science. 2018 Dec 14;362(6420). pii: eaat6720. doi: 10.1126\/science.aat6720<\/em>. PMID: 30545853<\/p>\n

Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk.<\/strong><\/a>
Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casi\u00f1o C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, Ho SM, MacDonald M, Hoffman GE<\/strong>, Roussos P<\/strong>, Zhang B, Hahn CG, Weng Z, Brennand KJ, Akbarian S.
Science. 2018 Dec 14;362(6420). pii: eaat4311. doi: 10.1126\/science.aat4311.<\/em> PMID: 30545851<\/p>\n

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.<\/strong><\/a>
Franceschini N, Giambartolomei C<\/strong>, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, Nolte IM, Lu L, Scholz M, Sargurupremraj M, Pitk\u00e4nen N, Franz\u00e9n O, Joshi PK, Noordam R, Marioni RE, Hwang SJ, Musani SK, Schminke U, Palmas W, Isaacs A, Correa A, Zonderman AB, Hofman A, Teumer A, Cox AJ, Uitterlinden AG, Wong A, Smit AJ, Newman AB, Britton A, Ruusalepp A, Sennblad B, Hedblad B, Pasaniuc B, Penninx BW, Langefeld CD, Wassel CL, Tzourio C, Fava C, Baldassarre D, O’Leary DH, Teupser D, Kuh D, Tremoli E, Mannarino E, Grossi E, Boerwinkle E, Schadt EE, Ingelsson E, Veglia F, Rivadeneira F, Beutner F, Chauhan G, Heiss G, Snieder H, Campbell H, V\u00f6lzke H, Markus HS, Deary IJ, Jukema JW, de Graaf J, Price J, Pott J, Hopewell JC, Liang J, Thiery J, Engmann J, Gertow K, Rice K, Taylor KD, Dhana K, Kiemeney LALM, Lind L, Raffield LM, Launer LJ, Holdt LM, D\u00f6rr M, Dichgans M, Traylor M, Sitzer M, Kumari M, Kivimaki M, Nalls MA, Melander O, Raitakari O, Franco OH, Rueda-Ochoa OL, Roussos P<\/strong>, Whincup PH, Amouyel P, Giral P, Anugu P, Wong Q, Malik R, Rauramaa R, Burkhardt R, Hardy R, Schmidt R, de Mutsert R, Morris RW, Strawbridge RJ, Wannamethee SG, H\u00e4gg S, Shah S, McLachlan S, Trompet S, Seshadri S, Kurl S, Heckbert SR, Ring S, Harris TB, Lehtim\u00e4ki T, Galesloot TE, Shah T, de Faire U, Plagnol V, Rosamond WD, Post W, Zhu X, Zhang X, Guo X, Saba Y; MEGASTROKE Consortium, Dehghan A, Seldenrijk A, Morrison AC, Hamsten A, Psaty BM, van Duijn CM, Lawlor DA, Mook-Kanamori DO, Bowden DW, Schmidt H, Wilson JF, Wilson JG, Rotter JI, Wardlaw JM, Deanfield J, Halcox J, Lyytik\u00e4inen LP, Loeffler M, Evans MK, Debette S, Humphries SE, V\u00f6lker U, Gudnason V, Hingorani AD, Bj\u00f6rkegren JLM, Casas JP, O’Donnell CJ.
Nat Commun. 2018 Dec 3;9(1):5141. doi: 10.1038\/s41467-018-07340-5.<\/em> PMID: 30510157<\/p>\n

Discovery of the first genome-wide significant risk loci for attention deficit\/hyperactivity disorder.<\/strong><\/a>
Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, Gandal M, Goldstein JI, Grasby KL, Grove J, Gudmundsson OO, Hansen CS, Hauberg ME<\/strong>, Hollegaard MV, Howrigan DP, Huang H, Maller JB, Martin AR, Martin NG, Moran J, Pallesen J, Palmer DS, Pedersen CB, Pedersen MG, Poterba T, Poulsen JB, Ripke S, Robinson EB, Satterstrom FK, Stefansson H, Stevens C, Turley P, Walters GB, Won H, Wright MJ; ADHD Working Group of the Psychiatric Genomics Consortium (PGC); Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium; 23andMe Research Team, Andreassen OA, Asherson P, Burton CL, Boomsma DI, Cormand B, Dalsgaard S, Franke B, Gelernter J, Geschwind D, Hakonarson H, Haavik J, Kranzler HR, Kuntsi J, Langley K, Lesch KP, Middeldorp C, Reif A, Rohde LA, Roussos P<\/strong>, Schachar R, Sklar P, Sonuga-Barke EJS, Sullivan PF, Thapar A, Tung JY, Waldman ID, Medland SE, Stefansson K, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Daly MJ, Faraone SV, B\u00f8rglum AD, Neale BM.
Nat Genet. 2019 Jan;51(1):63-75. doi: 10.1038\/s41588-018-0269-7. Epub 2018 Nov 26.<\/em> PMID: 30478444<\/p>\n

Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer’s disease and normalized by treatment with anti-diabetic agents.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Beeri MS, Gama-Sosa MA, Gandy S, Khan S, Haroutunian V.
PLoS One. 2018 Nov 1;13(11):e0206547. doi: 10.1371\/journal.pone.0206547. eCollection 2018. <\/em>PMID:30383799<\/p>\n

Adolescent exposure to \u03949<\/sup>-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons.<\/strong><\/a>
Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P<\/strong>, Shen L, Baxter MG, Hurd YL.
Mol Psychiatry. 2018 Oct 3. doi: 10.1038\/s41380-018-0243-x<\/em>. [Epub ahead of print] PMID:30283037<\/p>\n

mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia.<\/strong><\/a>
Wang HY, MacDonald ML, Borgmann-Winter KE, Banerjee A, Sleiman P, Tom A, Khan A, Lee KC, Roussos P<\/strong>, Siegel SJ, Hemby SE, Bilker WB, Gur RE, Hahn CG.
Mol Psychiatry. 2018 Sep 13. doi: 10.1038\/s41380-018-0234-y<\/em>. [Epub ahead of print] PMID: 30214040<\/p>\n

T<\/a><\/strong>he Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer\u2019s disease<\/a><\/strong>
Wang M, Beckmann ND, Roussos P<\/strong>, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF<\/strong>, Hauberg ME<\/strong>, Bendl J<\/strong>, Peters MA, Logsdon B, Wang P, Mahajan M, Mangravite LM, Dammer EB, Duong DM, Lah JJ, Seyfried NT, Levey AI, Buxbaum JD, Ehrlich M, Gandy S, Katsel P, Haroutunian V, Schadt E, Zhang B.
Sci Data. 2018 Sep 11;5:180185. <\/em>doi: 10.1038\/sdata.2018.185.<\/em> PMID: 30204156<\/p>\n

Evaluation of chromatin accessibility in prefrontal<\/a><\/strong> cortex of individuals with schizophrenia<\/strong>
<\/a>Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A,\u00a0Fullard JF<\/strong>,\u00a0Roussos P<\/strong>, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, White KP, Liu C, Reddy TE, Ashley-Koch A, Sullivan PF, Crawford GE.
Nat Commun. 2018 Aug 7;9(1):3121. doi: 10.1038\/s41467-018-05379-y.<\/em>\u00a0PMID: 30087329<\/p>\n

\n

Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome<\/a><\/strong><\/p>\n

\"Volume<\/div>\n

Girdhar K, Hoffman GE<\/strong>, Jiang Y, Brown L, Kundakovic M,\u00a0Hauberg ME, Francoeur NJ<\/strong>, Wang YC, Shah H, Kavanagh DH, Zharovsky E, Jacobov R, Wiseman JR, Park R, Johnson JS<\/strong>, Kassim BS, Sloofman L, Mattei E, Weng Z, Sieberts SK, Peters MA, Harris BT, Lipska BK, Sklar P,\u00a0Roussos P<\/strong>, Akbarian S.
Nat Neurosci. 2018 Jul 23. doi: 10.1038\/s41593-018-0187-0. [Epub ahead of print]\u00a0<\/em>PMID:30038276
\u2190 Featured at journal cover<\/strong> (art created by Jessica Johnson<\/a><\/strong>)<\/p>\n<\/div>\n

Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)<\/a><\/strong>
Lam M, Trampush JW, Yu J, Knowles E, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Hellard SL, Keller MC, Andreassen OA, Glahn DC, Malhotra AK, Lencz T.
Twin Res Hum Genet. 2018 Jul 13:1-4. doi: 10.1017\/thg.2018.46. [Epub ahead of print]<\/em>\u00a0PMID:30001766<\/p>\n

Age at first birth in women is genetically associated with increased risk of schizophrenia<\/a><\/strong>
Ni G, Gratten J, Wray NR, Lee SH;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>.
Sci Rep. 2018 Jul 5;8(1):10168. doi: 10.1038\/s41598-018-28160-z.\u00a0<\/em>PMID: 29977057<\/p>\n

An atlas of chromatin accessibility in the adult human brain<\/a><\/strong>
Fullard JF, Hauberg ME, Bendl J<\/strong>, Egervari G, Cirnaru MD,\u00a0Reach SM<\/strong>, Motl J, Ehrlich ME, Hurd YL,\u00a0Roussos P<\/strong>.
Genome Res. 2018 Jun 26. pii: gr.232488.117. doi: 10.1101\/gr.232488.117. [Epub ahead of print]\u00a0<\/em>PMID: 29945882<\/p>\n

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence<\/a><\/strong>
Savage JE, Jansen PR, Stringer S, Watanabe K,\u00a0\u2026,\u00a0Roussos P<\/strong>,\u00a0\u2026, Sullivan PF, Vrieze SI, Wright MJ, Posthuma D.
Nat Genet. 2018 Jun 25. doi: 10.1038\/s41588-018-0152-6. [Epub ahead of print]\u00a0<\/em>PMID:29942086<\/p>\n

Analysis of shared heritability in common disorders of the brain<\/a><\/strong>
Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L,\u00a0\u2026,\u00a0Roussos P<\/strong>,\u00a0\u2026,Sullivan P, Rosand J, Corvin A, Neale BM.
Science. 2018 Jun 22;360(6395). pii: eaap8757. doi: 10.1126\/science.aap8757.\u00a0<\/em>PMID: 29930110<\/p>\n

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes<\/a><\/strong>
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>. Electronic address: douglas.ruderfer@vanderbilt.edu; Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium.
Cell. 2018 Jun 14;173(7):1705-1715.e16. doi: 10.1016\/j.cell.2018.05.046.\u00a0<\/em>PMID: 29906448<\/p>\n

Brain Cell Type Specific Gene Expression and Co-expression Network Architectures<\/a><\/strong>
McKenzie AT, Wang M,\u00a0Hauberg ME, Fullard JF<\/strong>, Kozlenkov A, Keenan A, Hurd YL, Dracheva S, Casaccia P,\u00a0Roussos P<\/strong>, Zhang B.
Sci Rep. 2018 Jun 11;8(1):8868. doi: 10.1038\/s41598-018-27293-5.\u00a0<\/em>PMID: 29892006<\/p>\n

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function<\/a><\/strong>
Davies G, Lam M, Harris SE, Trampush JW,\u2026,\u00a0Roussos P<\/strong>,\u2026, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.
Nat Commun. 2018 May 29;9(1):2098. doi: 10.1038\/s41467-018-04362-x.\u00a0<\/em>PMID: 29844566<\/p>\n

Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS<\/a><\/strong>
Dobbyn A, Huckins LM, Boocock J, Sloofman LG, Glicksberg BS,\u00a0Giambartolomei C<\/strong>,\u00a0Hoffman GE,<\/strong>\u00a0Perumal TM,\u00a0Girdhar K<\/strong>, Jiang Y, Raj T, Ruderfer DM, Kramer RS, Pinto D; CommonMind Consortium, Akbarian S,\u00a0Roussos P<\/strong>, Domenici E, Devlin B, Sklar P, Stahl EA, Sieberts SK.
Am J Hum Genet. 2018 Jun 7;102(6):1169-1184. doi: 10.1016\/j.ajhg.2018.04.011. Epub 2018 May 24.\u00a0<\/em>PMID: 29805045<\/p>\n

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood<\/a><\/strong>
Ni G, Moser G;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Wray NR, Lee SH.
Am J Hum Genet. 2018 Apr 26. pii: S0002-9297(18)30110-1. doi: 10.1016\/j.ajhg.2018.03.021. [Epub ahead of print]<\/em>\u00a0PMID: 29754766<\/p>\n

Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls<\/a><\/strong>
Hauberg ME, Fullard JF,<\/strong>\u00a0Zhu L, Cohain AT,\u00a0Giambartolomei C, Misir R, Reach S,<\/strong>\u00a0Johnson JS<\/strong>, Wang M, Mattheisen M, B\u00f8rglum AD, Zhang B, Sieberts SK, Peters MA, Domenici E, Schadt EE, Devlin B, Sklar P, Roeder K,\u00a0Roussos P<\/strong>; CommonMind Consortium.
Mol Psychiatry. 2018 May 8. doi: 10.1038\/s41380-018-0059-8. [Epub ahead of print]<\/em>\u00a0PMID: 2974012<\/p>\n

THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders<\/a><\/strong>
Guennewig B, Bitar M, Obiorah I,\u00a0Hanks J,<\/strong>\u00a0O\u2019Brien EA, Kaczorowski DC, Hurd YL,\u00a0Roussos P<\/strong>, Brennand KJ, Barry G.
Transl Psychiatry. 2018 Apr 25;8(1):89. doi: 10.1038\/s41398-018-0137-3<\/em>. PMID:2969137<\/p>\n

A Bayesian Framework for Multiple Trait Colo-calization from Summary Association Statistics<\/a><\/strong>
Giambartolomei C,<\/strong>\u00a0Zhenli Liu J,\u00a0Zhang W, Hauberg M,<\/strong>\u00a0Shi H, Boocock J, Pickrell J, Jaffe AE; CommonMind Consortium, Pasaniuc B,\u00a0Roussos P<\/strong>.
Bioinformatics. 2018 Mar 19. doi: 10.1093\/bioinformatics\/bty147. [Epub ahead of print]<\/em>\u00a0PMID:29579179<\/p>\n

Frontal and temporal cortical volume, white matter tract integrity, and hemispheric asymmetry in schizotypal personality disorder<\/strong>
<\/a>Chan CC, Szeszko PR, Wong E, Tang CY, Kelliher C, Penner JD, Perez-Rodriguez MM, Rosell DR, McClure M,\u00a0Roussos P<\/strong>, New AS, Siever LJ, Hazlett EA.
Schizophr Res. 2018 Feb 14<\/em>. pii: S0920-9964(18)30047-1. doi: 10.1016\/j.schres.2018.01.025. [Epub ahead of print] PMID:29454512<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2017″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2017″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Meta-analysis on the association between genetic polymorphisms and prepulse inhibition of the acoustic startle response<\/a><\/strong>
Quednow BB,\u00a0Ejebe K<\/strong>, Wagner M, Giakoumaki SG, Bitsios P, Kumari V,\u00a0Roussos P<\/strong>.
Schizophr Res. 2017 Dec 26. pii: S0920-9964(17)30763-6. doi: 10.1016\/j.schres.2017.12.011. [Epub ahead of print]<\/em>\u00a0PMID: 29287625<\/p>\n

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets<\/a><\/strong>
Lam M, Trampush JW, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Cell Rep<\/em>. 2017 Nov 28;21(9):2597-2613. doi: 10.1016\/j.celrep.2017.11.028<\/em>. PMID: 29186694<\/p>\n

Winter birth, urbanicity and immigrant status predict psychometric schizotypy dimensions in adolescents<\/a><\/strong>
Mimarakis D, Roumeliotaki T,\u00a0Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Eur Psychiatry<\/em>. 2017 Sep 18;47:9-18. doi: 10.1016\/j.eurpsy.2017.07.014. [Epub ahead of print]\u00a0<\/em>PMID: 29096131<\/p>\n

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium<\/a><\/strong>
Trampush JW, Yang MLZ, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Mol Psychiatry<\/em>. 2017 Nov;22(11):1651-1652. doi: 10.1038\/mp.2017. 197.\u00a0 Epub 2017 Sep 12.\u00a0<\/em>PMID: 29068436<\/p>\n

Stress-Dependent Association Between Polygenic Risk for Schizophrenia and Schizotypal Traits in Young Army Recruits<\/a><\/strong>
Hatzimanolis A, Avramopoulos D, Arking DE, Moes A, Bhatnagar P, Lencz T, Malhotra AK, Giakoumaki SG,\u00a0Roussos P<\/strong>, Smyrnis N, Bitsios P, Stefanis NC.
Schizophr Bull. 2017 Jun 13. doi: 10.1093\/schbul\/sbx074. [Epub ahead of print]\u00a0<\/em>PMID: 29036523<\/p>\n

A functional genomics predictive network model identifies regulators of inflammatory bowel disease<\/a><\/strong>
Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K,\u00a0Roussos P<\/strong>, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE.
Nat Genet. 2017 Oct;49(10):1437-1449. doi: 10.1038\/ng.3947. Epub 2017 Sep 11<\/em>. PMID: 28892060<\/p>\n

Dimensional Traits of Schizotypy Associated With Glycine Receptor GLRA1 Polymorphism: An Exploratory Candidate-Gene Association Study<\/a><\/strong>
Vora AK<\/strong>, Fisher AM, New AS, Hazlett EA, McNamara M, Yuan Q, Zhou Z, Hodgkinson C, Goldman D, Siever LJ,\u00a0Roussos P<\/strong>, Perez-Rodriguez MM.
J Pers Disord. 2017 Jul 31:1-12. doi: 10.1521\/pedi_2017_31_303. [Epub ahead of print]\u00a0<\/em>PMID: 28758885<\/p>\n

The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain<\/a><\/strong>
Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, Peter CJ, C W JT, Safaie BM, Morishita H,\u00a0Roussos P<\/strong>, Nestler EJ, Schaefer A, Tycko B, Brennand KJ, Yagi T, Shen L, Akbarian S.
Nat Genet. 2017 Aug;49(8):1239-1250. doi: 10.1038\/ng.3906. Epub 2017 Jul 3<\/em>. PMID: 28671686<\/p>\n

Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression<\/a><\/strong>
Hauberg ME<\/strong>,\u00a0Zhang W<\/strong>,\u00a0Giambartolomei C<\/strong>, Franz\u00e9n O, Morris DL, Vyse TJ, Ruusalepp A; CommonMind Consortium, Sklar P, Schadt EE, Bj\u00f6rkegren JLM,\u00a0Roussos P<\/strong>.
Am J Hum Genet. 2017 Jun 1;100(6):885-894. doi: 10.1016\/j.ajhg. 2017.04.016. Epub 2017 May 25.\u00a0<\/em>PMID:28552197<\/p>\n

minepath.org: a free interactive pathway analysis web server<\/strong><\/a>
Koumakis L,\u00a0Roussos P<\/strong>, Potamias G.
Nucleic Acids Res. 2017 Apr 20. doi: 10.1093\/nar\/gkx278. [Epub ahead of print]<\/em>\u00a0PMID: 28431175<\/p>\n

Microvascular anomaly conditions in psychiatric disease. Schizophrenia \u2013 angiogenesis connection<\/a><\/strong>
Katsel P,\u00a0Roussos P<\/strong>, Pletnikov M, Haroutunian V.
Neurosci Biobehav Rev. 2017 Jun;77:327-339. doi: 10.1016\/j.neubiorev.2017.04.003. Epub 2017 Apr 8. Review.<\/em>\u00a0PMID: 28396239<\/p>\n

Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci<\/a><\/strong>
Fullard JF, Giambartolomei C, Hauberg ME,<\/strong>\u00a0Xu K,\u00a0Voloudakis G<\/strong>, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V,\u00a0Roussos P<\/strong>.
Hum Mol Genet. 2018 Jun 29. doi: 10.1093\/hmg\/ddy229. [Epub ahead of print] No abstract available<\/em>. PMID: 29982455<\/p>\n

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia<\/a><\/strong>
McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O\u2019Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>.
Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038\/ncomms14774.<\/em>\u00a0PMID: 28322246<\/p>\n

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium<\/a><\/strong>
Trampush JW, Yang ML, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Mol Psychiatry. 2017 Mar;22(3):336-345. doi: 10.1038\/mp. 2016.244. Epub 2017 Jan 17.<\/em>\u00a0PMID: 28093568<\/p>\n

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder<\/a><\/strong>
Charney AW, Ruderfer DM, Stahl EA, Moran JL, Chambert K, Belliveau RA, Forty L, Gordon-Smith K, Di Florio A, Lee PH, Bromet EJ, Buckley PF, Escamilla MA, Fanous AH, Fochtmann LJ, Lehrer DS, Malaspina D, Marder SR, Morley CP, Nicolini H, Perkins DO, Rakofsky JJ, Rapaport MH, Medeiros H, Sobell JL, Green EK, Backlund L, Bergen SE, Jur\u00e9us A, Schalling M, Lichtenstein P,\u00a0Roussos P<\/strong>, Knowles JA, Jones I, Jones LA, Hultman CM, Perlis RH, Purcell SM, McCarroll SA, Pato CN, Pato MT, Craddock N, Land\u00e9n M, Smoller JW, Sklar P.
Transl Psychiatry. 2017 Jan 10;7(1):e993. doi: 10.1038\/tp.2016.242.<\/em>\u00a0PMID: 28072414<\/p>\n

Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity<\/a><\/strong>
Carcamo-Orive I,\u00a0Hoffman GE,<\/strong>\u00a0Cundiff P, Beckmann ND, D\u2019Souza SL, Knowles JW, Patel A, Papatsenko D, Abbasi F, Reaven GM, Whalen S, Lee P, Shahbazi M, Henrion MY, Zhu K, Wang S,\u00a0Roussos P<\/strong>, Schadt EE, Pandey G, Chang R, Quertermous T, Lemischka I.
Cell Stem Cell. 2017 Apr 6;20(4):518-532.e9. doi: 10.1016\/j.stem. 2016.11.005. Epub 2016 Dec 22.<\/em>\u00a0PMID: 2801779<\/p>\n

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects<\/a><\/strong>
Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, \u2026,\u00a0Roussos P<\/strong>, \u2026, Scherer SW, Neale BM, Sebat J; CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium.
Nat Genet. 2017 Jan;49(1):27-35. doi: 10.1038\/ng.3725. Epub 2016 Nov 21.<\/em>\u00a0PMID: 27869829<\/p>\n

Striatal H3K27 Acetylation Linked to Glutamatergic Gene Dysregulation in Human Heroin Abusers Holds Promise as Therapeutic Target<\/a><\/strong>
Egervari G, Landry J, Callens J,\u00a0Fullard JF<\/strong>,\u00a0Roussos P<\/strong>, Keller E, Hurd YL.
Biol Psychiatry. 2017 Apr 1;81(7):585-594. doi: 10.1016\/j.biopsych. 2016.09.015. Epub 2016 Sep 28.\u00a0<\/em>PMID:27863698<\/p>\n

\u00a0<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2016″ icon_color=”#00aeef” admin_label=”2016″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Activity-Dependent Changes in Gene Expression in Schizophrenia Human-Induced Pluripotent Stem Cell Neurons
<\/a><\/strong>Roussos P<\/strong>, Guennewig B, Kaczorowski DC, Barry G, Brennand KJ.
<\/span>JAMA Psychiatry. 2016 Nov 1;73(11):1180-1188. doi: 10.1001\/jamapsychiatry.2016.2575.<\/em>\u00a0PMID: 27732689<\/p>\n

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer\u2019s disease<\/a><\/strong>
Wang M,\u00a0Roussos P<\/strong>, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, Haroutunian V, Zhang B.
Genome Med. 2016 Nov 1;8(1):104.<\/em>\u00a0PMID: 27799057<\/p>\n

Gene expression elucidates functional impact of polygenic risk for schizophrenia<\/a><\/strong>
Fromer M,\u00a0Roussos P<\/strong>, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, G\u00fcm\u00fc\u015f ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T,\u00a0Fullard JF<\/strong>, Wang YC, Mahajan MC, Derry JM, Dudley JT, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn CG, Lewis DA, Haroutunian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hirai K, Roeder K, Brennand KJ, Katsanis N, Domenici E, Devlin B, Sklar P.
Nat Neurosci. 2016 Nov;19(11):1442-1453. doi: 10.1038\/nn.4399. Epub 2016 Sep 26.<\/em>\u00a0PMID: 27668389<\/p>\n

Associations of differential schizotypal dimensions with executive working memory: A moderated-mediation analysis<\/strong><\/a>
Zouraraki C, Tsaousis I, Karamaouna P, Karagiannopoulou L,\u00a0Roussos P<\/strong>, Bitsios P, Giakoumaki SG.
Compr Psychiatry. 2016 Nov;71:39-48. doi: 10.1016\/j.comppsych. 2016.08.010. Epub 2016 Aug 21.\u00a0<\/em>PMID: 27621208<\/p>\n

Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases<\/strong><\/a>
Franz\u00e9n O, Ermel R, Cohain A, Akers NK, Di Narzo A, Talukdar HA, Foroughi-Asl H,\u00a0Giambartolomei C<\/strong>,\u00a0Fullard JF<\/strong>, Sukhavasi K, K\u00f6ks S, Gan LM, Giannarelli C, Kovacic JC, Betsholtz C, Losic B, Michoel T, Hao K,\u00a0Roussos P<\/strong>, Skogsberg J, Ruusalepp A, Schadt EE, Bj\u00f6rkegren JL.
Science. 2016 Aug 19;353(6301):827-30. doi: 10.1126\/science.aad 6970.\u00a0<\/em>PMID: 27540175<\/p>\n

Cognitive profiles of schizotypal dimensions in a community cohort: Common properties of differential manifestations<\/a><\/strong>
Karagiannopoulou L, Karamaouna P, Zouraraki C,\u00a0Roussos P<\/strong>, Bitsios P, Giakoumaki SG.
J Clin Exp Neuropsychol. 2016 Nov;38(9):1050-63. doi: 10.1080\/13803395.2016.1188890. Epub 2016 Jun 13.\u00a0<\/em>PMID: 27295077<\/p>\n

Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue<\/a><\/strong>
Kundakovic M, Jiang Y, Kavanagh DH, Dincer A, Brown L, Pothula V, Zharovsky E, Park R, Jacobov R, Magro I, Kassim B, Wiseman J, Dang K, Sieberts SK,\u00a0Roussos P<\/strong>, Fromer M, Harris B, Lipska BK, Peters MA, Sklar P, Akbarian S.
Biol Psychiatry. 2017 Jan 15;81(2):162-170. doi: 10.1016\/j.biopsych. 2016.03.1048. Epub 2016 Mar 9.\u00a0<\/em>PMID: 27113501<\/p>\n

Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants<\/a><\/strong>
Hauberg ME<\/strong>,\u00a0Roussos P<\/strong>, Grove J, B\u00f8rglum AD, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium.
JAMA Psychiatry. 2016 Apr;73(4):369-77. doi: 10.1001\/jamapsychiatry.2015.3018.\u00a0<\/em>PMID: 26963595<\/p>\n

Understanding the genetic liability to schizophrenia through the neuroepigenome<\/a><\/strong>
Fullard JF<\/strong>, Halene TB,\u00a0Giambartolomei C<\/strong>, Haroutunian V, Akbarian S,\u00a0Roussos P<\/strong>.Schizophr Res. 2016 Nov;177(1-3):115-124. doi: 10.1016\/j.schres.2016.01.039. Epub 2016 Jan 27. Review.\u00a0<\/em>PMID: 26827128<\/p>\n

Schizophrenia risk from complex variation of complement component 4<\/a><\/strong>
Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Daly MJ, Carroll MC, Stevens B, McCarroll SA.
Nature. 2016 Feb 11;530(7589):177-83. doi: 10.1038\/nature16549. Epub 2016 Jan 27.\u00a0<\/em>PMID: 26814963<\/p>\n

Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer\u2019s disease<\/a><\/strong>
Watson CT,\u00a0Roussos P<\/strong>, Garg P, Ho DJ, Azam N, Katsel PL, Haroutunian V, Sharp AJ.
Genome Med. 2016 Jan 19;8(1):5. doi: 10.1186\/s13073-015-0258-8.\u00a0<\/em>PMID: 26803900<\/p>\n

NeuN+ neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure<\/a><\/strong>
Halene TB, Kozlenkov A, Jiang Y, Mitchell AC, Javidfar B, Dincer A, Park R, Wiseman J, Croxson PL, Giannaris EL, Hof PR,\u00a0Roussos P<\/strong>, Dracheva S, Hemby SE, Akbarian S.
Schizophr Res. 2016 Feb;170(2-3):235-44. doi: 10.1016\/j.schres. 2015.12.016. Epub 2016 Jan 6.\u00a0<\/em>PMID: 26776227<\/p>\n

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness<\/a><\/strong>
Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, Werge T, Blackwood DH, Pato CN, Pato MT, Malhotra AK, O\u2019Donovan MC, Kendler KS, Fanous AH;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>.
Am J Med Genet B Neuropsychiatr Genet. 2016 Mar;171B(2):276-89. doi: 10.1002\/ajmg.b.32402. Epub 2015 Dec 11.\u00a0<\/em>PMID: 26663532<\/p>\n

Substantial DNA methylation differences between two major neuronal subtypes in human brain<\/a><\/strong>
Kozlenkov A, Wang M,\u00a0Roussos P<\/strong>, Rudchenko S, Barbu M, Bibikova M, Klotzle B, Dwork AJ, Zhang B, Hurd YL, Koonin EV, Wegner M, Dracheva S.
Nucleic Acids Res. 2016 Apr 7;44(6):2593-612. doi: 10.1093\/nar\/gkv1304. Epub 2015 Nov 26.\u00a0<\/em>PMID: 26612861<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2015″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2015″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington\u2019s Disease<\/a><\/strong>
Dong X, Tsuji J, Labadorf A,\u00a0Roussos P<\/strong>, Chen JF, Myers RH, Akbarian S, Weng Z.
PLoS One. 2015 Dec 4;10(12):e0144398. doi: 10.1371\/journal.pone. 0144398. eCollection 2015.\u00a0<\/em>PMID: 26636336<\/p>\n

The PsychENCODE project<\/a><\/strong>
PsychENCODE Consortium, Akbarian S, Liu C, Knowles JA, Vaccarino FM, Farnham PJ, Crawford GE, Jaffe AE, Pinto D, Dracheva S, Geschwind DH, Mill J, Nairn AC, Abyzov A, Pochareddy S, Prabhakar S, Weissman S, Sullivan PF, State MW, Weng Z, Peters MA, White KP, Gerstein MB, Amiri A, Armoskus C, Ashley-Koch AE, Bae T, Beckel-Mitchener A, Berman BP, Coetzee GA, Coppola G, Francoeur N, Fromer M, Gao R, Grennan K, Herstein J, Kavanagh DH, Ivanov NA, Jiang Y, Kitchen RR, Kozlenkov A, Kundakovic M, Li M, Li Z, Liu S, Mangravite LM, Mattei E, Markenscoff-Papadimitriou E, Navarro FC, North N, Omberg L, Panchision D, Parikshak N, Poschmann J, Price AJ, Purcaro M, Reddy TE,\u00a0Roussos P<\/strong>, Schreiner S, Scuderi S, Sebra R, Shibata M, Shieh AW, Skarica M, Sun W, Swarup V, Thomas A, Tsuji J, van Bakel H, Wang D, Wang Y, Wang K, Werling DM, Willsey AJ, Witt H, Won H, Wong CC, Wray GA, Wu EY, Xu X, Yao L, Senthil G, Lehner T, Sklar P, Sestan N.
Nat Neurosci. 2015 Dec;18(12):1707-12. doi: 10.1038\/nn.4156. Review. No abstract available.\u00a0<\/em>PMID: 26605881<\/p>\n

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis<\/a><\/strong>
Loh PR, Bhatia G, Gusev A, Finucane HK, Bulik-Sullivan BK, Pollack SJ;\u00a0Schizophrenia Working Group of Psychiatric Genomics Consortium,<\/strong>\u00a0de Candia TR, Lee SH, Wray NR, Kendler KS, O\u2019Donovan MC, Neale BM, Patterson N, Price AL.
Nat Genet. 2015 Dec;47(12):1385-92. doi: 10.1038\/ng.3431. Epub 2015 Nov 2.\u00a0<\/em>PMID: 26523775<\/p>\n

Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease<\/a><\/strong>
Won HH, Natarajan P, Dobbyn A, Jordan DM,\u00a0Roussos P<\/strong>, Lage K, Raychaudhuri S, Stahl E, Do R.
PLoS Genet. 2015 Oct 28;11(10):e1005622. doi: 10.1371\/journal. pgen.1005622. eCollection 2015 Oct.\u00a0<\/em>PMID: 26509271<\/p>\n

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder<\/a><\/strong>
Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, Stahl EA; Members of the International Cohort Collection for Bipolar Disorder (ICCBD), Chambert KD, Moran JL, Gordon-Smith K, Forty L, Green EK, Jones I, Jones L, Scolnick EM, Sklar P, Smoller JW, Lichtenstein P, Hultman C, Craddock N, Land\u00e9n M, Smoller JW, Perlis RH, Lee PH, Castro VM, Hoffnagle AG, Sklar P, Stahl EA, Purcell SM, Ruderfer DM, Charney AW,\u00a0Roussos P<\/strong>, Michele Pato CP, Medeiros H, Sobel J, Craddock N, Jones I, Forty L, Florio AD, Green E, Jones L, Gordon-Smith K, Landen M, Hultman C, Jureus A, Bergen S, McCarroll S, Moran J, Smoller JW, Chambert K, Belliveau RA.
Mol Psychiatry. 2016 Sep;21(9):1290-7. doi: 10.1038\/mp.2015.165. Epub 2015 Oct 27. Erratum in:\u00a0Mol Psychiatry. 2017 Aug;22(8):1223<\/a>.\u00a0<\/em>PMID: 26503763<\/p>\n

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores<\/a><\/strong>
Vilhj\u00e1lmsson BJ, Yang J, Finucane HK, Gusev A, Lindstr\u00f6m S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study, Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL.
Am J Hum Genet. 2015 Oct 1;97(4):576-92. doi: 10.1016\/j.ajhg. 2015.09.001.\u00a0<\/em>PMID: 26430803<\/p>\n

Genome-wide autozygosity is associated with lower general cognitive ability<\/a><\/strong>
Howrigan DP, Simonson MA, Davies G, Harris SE, Tenesa A, Starr JM, Liewald DC, Deary IJ, McRae A, Wright MJ, Montgomery GW, Hansell N, Martin NG, Payton A, Horan M, Ollier WE, Abdellaoui A, Boomsma DI, DeRosse P, Knowles EE, Glahn DC, Djurovic S, Melle I, Andreassen OA, Christoforou A, Steen VM, Hellard SL, Sundet K, Reinvang I, Espeseth T, Lundervold AJ, Giegling I, Konte B, Hartmann AM, Rujescu D,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Bitsios P, Donohoe G, Corley RP, Visscher PM, Pendleton N, Malhotra AK, Neale BM, Lencz T, Keller MC.
Mol Psychiatry. 2016 Jun;21(6):837-43. doi: 10.1038\/mp.2015.120. Epub 2015 Sep 22.\u00a0<\/em>PMID: 26390830<\/p>\n

The Relationship of Common Risk Variants and Polygenic Risk for Schizophrenia to Sensorimotor Gating<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Zouraraki C,\u00a0Fullard JF<\/strong>,\u00a0Karagiorga VE<\/strong>, Tsapakis EM, Petraki Z, Siever LJ, Lencz T, Malhotra A, Spanaki C, Bitsios P.
Biol Psychiatry. 2016 Jun 15;79(12):988-96. doi: 10.1016\/j.biopsych. 2015.06.019. Epub 2015 Jun 27.\u00a0<\/em>PMID: 26212897<\/p>\n

Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia<\/a><\/strong>
Rees E, Kirov G, Walters JT, Richards AL, Howrigan D, Kavanagh DH, Pocklington AJ, Fromer M, Ruderfer DM, Georgieva L, Carrera N, Gormley P, Palta P, Williams H, Dwyer S, Johnson JS,\u00a0Roussos P<\/strong>, Barker DD, Banks E, Milanova V, Rose SA, Chambert K, Mahajan M, Scolnick EM, Moran JL, Tsuang MT, Glatt SJ, Chen WJ, Hwu HG; Taiwanese Trios Exome Sequencing Consortium, Neale BM, Palotie A, Sklar P, Purcell SM, McCarroll SA, Holmans P, Owen MJ, O\u2019Donovan MC.
Transl Psychiatry. 2015 Jul 21;5:e607. doi: 10.1038\/tp.2015.99<\/em>. PMID:26196440<\/p>\n

Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophrenia<\/a><\/strong>
O\u2019Donovan SM, Hasselfeld K, Bauer D, Simmons M,\u00a0Roussos P<\/strong>, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.
Transl Psychiatry. 2015 Jun 9;5:e579. doi: 10.1038\/tp.2015.74.\u00a0<\/em>PMID: 26057049<\/p>\n

Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood<\/a><\/strong>
Hatzimanolis A, Bhatnagar P, Moes A, Wang R,\u00a0Roussos P<\/strong>, Bitsios P, Stefanis CN, Pulver AE, Arking DE, Smyrnis N, Stefanis NC, Avramopoulos D.
Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168B(5):392-401. doi: 10.1002\/ajmg.b.32323. Epub 2015 May 12.\u00a0<\/em>PMID: 25963331<\/p>\n

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment<\/a><\/strong>
Trampush JW, Lencz T, Knowles E, Davies G, Guha S, Pe\u2019er I, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Ikeda M,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Scult M, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri A, Weinberger DR, Pendleton N, Iwata N, Darvasi A, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK.
Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168B(5):363-73. doi: 10.1002\/ajmg.b.32319. Epub<\/em>\u00a02015 May 7. PMID: 25951819<\/p>\n

The effects of the CACNA1C rs1006737 A\/G on affective startle modulation in healthy males<\/a><\/strong>
Pasparakis E, Koiliari E, Zouraraki C, Tsapakis EM,\u00a0Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Eur Psychiatry. 2015 Jun;30(4):492-8. doi: 10.1016\/j.eurpsy. 2015.03.004. Epub 2015 Apr 1.\u00a0<\/em>PMID: 25841664<\/p>\n

Validation of electronic health record phenotyping of bipolar disorder cases and controls<\/a><\/strong>
Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW;\u00a0International Cohort Collection for Bipolar Disorder Consortium<\/strong>.
Am J Psychiatry. 2015 Apr;172(4):363-72. doi: 10.1176\/appi.ajp. 2014.14030423. Epub 2014 Dec 12.\u00a0<\/em>PMID: 25827034<\/p>\n

Integration of gene expression and GWAS results supports <\/strong>involvement of calcium <\/strong>signaling in Schizophrenia<\/strong><\/a>
Hertzberg L, Katsel P,\u00a0Roussos P<\/strong>, Haroutunian V, Domany E.
Schizophr Res. 2015 May;164(1-3):92-9. doi: 10.1016\/j.schres. 2015.02.001. Epub 2015 Feb 20.\u00a0<\/em>PMID: 25702973<\/p>\n

Genomic and network patterns of schizophrenia genetic variation in human evolutionary accelerated regions<\/strong>
<\/a>Xu K, Schadt EE, Pollard KS,\u00a0Roussos P<\/strong>, Dudley JT.
Mol Biol Evol. 2015 May;32(5):1148-60. doi: 10.1093\/molbev\/msv031. Epub 2015 Feb 12.<\/em>\u00a0PMID: 25681384<\/p>\n

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies<\/strong>
<\/a>Bulik-Sullivan BK, Loh PR, Finucane HK, Ripke S, Yang J;<\/span>\u00a0<\/span>Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Patterson N, Daly MJ, Price AL, Neale BM.<\/span>Nat Genet. 2015 Mar;47(3):291-5. doi: 10.1038\/ng.3211. Epub 2015 Feb 2.\u00a0<\/em>PMID: 25642630<\/p>\n

The relationship between dopamine receptor D1 and cognitive performance<\/strong>
<\/a>Tsang J<\/strong>,\u00a0Fullard JF<\/strong>, Giakoumaki SG, Katsel P, Katsel P,\u00a0Karagiorga VE<\/strong>, Greenwood TA, Braff DL, Siever LJ, Bitsios P, Haroutunian V,\u00a0Roussos P<\/strong>.
NPJ Schizophr. 2015 Mar 4;1:14002. doi: 10.1038\/npjschz.2014.2. eCollection 2015. Erratum in:\u00a0NPJ Schizophr. 2015;1:15018<\/a>.\u00a0<\/em>PMID: 27336024<\/p>\n

The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer\u2019s dementia<\/a><\/strong>
Roussos P<\/strong>, Katsel P, Fam P, Tan W, Purohit DP, Haroutunian V.
Alzheimers Dement. 2015 Oct;11(10):1163-70. doi: 10.1016\/j.jalz. 2014.10.013. Epub 2014 Dec 9.\u00a0<\/em>PMID: 25499537<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2014″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2014″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition<\/a><\/strong>
Bharadwaj R, Peter CJ, Jiang Y,\u00a0Roussos P<\/strong>, Vogel-Ciernia A, Shen EY, Mitchell AC, Mao W, Whittle C, Dincer A, Jakovcevski M, Pothula V, Rasmussen TP, Giakoumaki SG, Bitsios P, Sherif A, Gardner PD, Ernst P, Ghose S, Sklar P, Haroutunian V, Tamminga C, Myers RH, Futai K, Wood MA, Akbarian S.
Neuron. 2014 Dec 3;84(5):997-1008. doi: 10.1016\/j.neuron. 2014.10.032. Epub 2014 Nov 13.\u00a0<\/em>PMID: 25467983<\/p>\n

A role for noncoding variation in schizophrenia<\/a><\/strong>
Roussos P<\/strong>, Mitchell AC,\u00a0Voloudakis G, Fullard JF<\/strong>, Pothula VM,\u00a0Tsang J<\/strong>, Stahl EA, Georgakopoulos A, Ruderfer DM, Charney A, Okada Y, Siminovitch KA, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Plenge RM, Raychaudhuri S, Fromer M, Purcell SM, Brennand KJ, Robakis NK, Schadt EE, Akbarian S, Sklar P.
Cell Rep. 2014 Nov 20;9(4):1417-29. doi: 10.1016\/j.celrep. 2014.10.015. Epub 2014 Nov 6.\u00a0<\/em>PMID: 25453756<\/p>\n

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases<\/a><\/strong>
Gusev A, Lee SH, Trynka G, Finucane H, Vilhj\u00e1lmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium, K\u00e4hler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>; SWE-SCZ Consortium.
Am J Hum Genet. 2014 Nov 6;95(5):535-52. doi: 10.1016\/j.ajhg. 2014.10.004. Epub 2014 Nov 6.\u00a0<\/em>PMID: 25439723<\/p>\n

The future of neuroepigenetics in the human brain<\/a><\/strong>
Mitchell A,\u00a0Roussos P<\/strong>, Peter C, Tsankova N, Akbarian S.
Prog Mol Biol Transl Sci. 2014;128:199-228. doi: 10.1016\/ B978-0-12-800977-2.00008-5. Review.\u00a0<\/em>PMID: 25410546<\/p>\n

Myelination, oligodendrocytes, and serious mental illness<\/a><\/strong>
Haroutunian V, Katsel P,\u00a0Roussos P<\/strong>, Davis KL, Altshuler LL, Bartzokis G.
Glia. 2014 Nov;62(11):1856-77. doi: 10.1002\/glia.22716. Epub 2014 Jul 23. Review.\u00a0<\/em>PMID: 25056210<\/p>\n

Biological insights from 108 schizophrenia-associated genetic loci<\/a><\/strong>
Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>.
Nature. 2014 Jul 24;511(7510):421-7. doi: 10.1038\/nature13595. Epub 2014 Jul 22.\u00a0<\/em>PMID: 25056061<\/p>\n

A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicid<\/strong>e<\/a>
Di Narzo AF, Kozlenkov A,\u00a0Roussos P<\/strong>, Hao K, Hurd Y, Lewis DA, Sibille E, Siever LJ, Koonin E, Dracheva S.
Hum Mol Genet. 2014 Sep 15;23(18):4801-13. doi: 10.1093\/hmg\/ddu195. Epub 2014 Apr 29.\u00a0<\/em>PMID: 24781207<\/p>\n

The CSMD1 genome-wide associated schizophrenia risk variant rs10503253 affects <\/strong>general cognitive ability and executive function in healthy males<\/strong><\/a>
Koiliari E,\u00a0Roussos P<\/strong>, Pasparakis E, Lencz T, Malhotra A, Siever LJ, Giakoumaki SG, Bitsios P.
Schizophr Res. 2014 Apr;154(1-3):42-7. doi: 10.1016\/j.schres. 2014.02.017. Epub 2014 Mar 11.\u00a0<\/em>PMID: 24630139<\/p>\n

Schizophrenia: susceptibility genes and oligodendroglial and myelin related abnormalities<\/a><\/strong>
Roussos P<\/strong>, Haroutunian V.
Front Cell Neurosci. 2014 Jan 21;8:5. doi: 10.3389\/fncel.2014.00005. eCollection 2014. Review.\u00a0<\/em>PMID: 24478629<\/p>\n

A polygenic burden of rare disruptive mutations in schizophrenia<\/a><\/strong>
Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N,\u00a0Roussos P<\/strong>, O\u2019Dushlaine C, Chambert K, Bergen SE, K\u00e4hler A, Duncan L, Stahl E, Genovese G, Fern\u00e1ndez E, Collins MO, Komiyama NH, Choudhary JS, Magnusson PK, Banks E, Shakir K, Garimella K, Fennell T, DePristo M, Grant SG, Haggarty SJ, Gabriel S, Scolnick EM, Lander ES, Hultman CM, Sullivan PF, McCarroll SA, Sklar P.
Nature. 2014 Feb 13;506(7487):185-90. doi: 10.1038\/nature12975. Epub 2014 Jan 22.\u00a0<\/em>PMID: 24463508<\/p>\n

De novo mutations in schizophrenia implicate synaptic networks<\/a><\/strong>
Fromer M, Pocklington AJ, Kavanagh DH, Williams HJ, Dwyer S, Gormley P, Georgieva L, Rees E, Palta P, Ruderfer DM, Carrera N, Humphreys I, Johnson JS,\u00a0Roussos P<\/strong>, Barker DD, Banks E, Milanova V, Grant SG, Hannon E, Rose SA, Chambert K, Mahajan M, Scolnick EM, Moran JL, Kirov G, Palotie A, McCarroll SA, Holmans P, Sklar P, Owen MJ, Purcell SM, O\u2019Donovan MC.
Nature. 2014 Feb 13;506(7487):179-84. doi: 10.1038\/nature12929.<\/em>\u00a0Epub 2014 Jan 22. PMID: 24463507<\/p>\n

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)<\/a><\/strong>
Lencz T, Knowles E, Davies G, Guha S, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Ikeda M,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Donohoe G, Morris D, Corvin A, Gill M, Pendleton N, Iwata N, Darvasi A, Bitsios P, Rujescu D, Lahti J, Hellard SL, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK.
Mol Psychiatry. 2014 Feb;19(2):168-74. doi: 10.1038\/mp.2013.166. Epub 2013 Dec 17.\u00a0<\/em>PMID: 24342994<\/p>\n

Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites<\/a><\/strong>
Kozlenkov A,\u00a0Roussos P<\/strong>, Timashpolsky A, Barbu M, Rudchenko S, Bibikova M, Klotzle B, Byne W, Lyddon R, Di Narzo AF, Hurd YL, Koonin EV, Dracheva S.
Nucleic Acids Res. 2014 Jan;42(1):109-27. doi: 10.1093\/nar\/gkt838. Epub 2013 Sep 20.\u00a0<\/em>PMID: 24057217<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2013″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2013″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Cognitive and personality analysis of startle reactivity in a large cohort of healthy males<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Tsapakis EM, Koiliari E, Pasparakis E, Zouraraki C, Bitsios P.
Biol Psychol. 2013 Dec;94(3):582-91. doi: 10.1016\/j.biopsycho. 2013.09.005. Epub 2013 Sep 16.\u00a0<\/em>PMID: 24051230<\/p>\n

Schizoid personality disorder<\/a><\/strong>
Triebwasser J, Chemerinski E,\u00a0Roussos P<\/strong>, Siever LJ.
J Pers Disord. 2012 Dec;26(6):919-26. doi: 10.1521\/pedi. 2012.26.6.919. Review<\/em>. PMID: 23281676<\/p>\n

Convergent findings for abnormalities of the NF-\u03baB signaling pathway in schizophrenia<\/a><\/strong>
Roussos P<\/strong>, Katsel P, Davis KL, Giakoumaki SG, Lencz T, Malhotra AK, Siever LJ, Bitsios P, Haroutunian V.
Neuropsychopharmacology. 2013 Feb;38(3):533-9. doi: 10.1038\/npp.2012.215. Epub 2012 Nov 7. Erratum in: Neuropsychopharmacology. 2013 Mar;38(4):699. Lencz, Todd [added]; Malhotra, Anil K [added].\u00a0<\/em>PMID: 23132271<\/p>\n

Sub-optimal parenting is associated with schizotypic and anxiety personality traits in adulthood<\/strong>
<\/a>Giakoumaki SG,\u00a0Roussos P<\/strong>, Zouraraki C, Spanoudakis E, Mavrikaki M, Tsapakis EM, Bitsios P.
Eur Psychiatry. 2013 May;28(4):254-60. doi: 10.1016\/j.eurpsy. 2012.07.002. Epub 2012 Oct 10.\u00a0<\/em>PMID: 23062835<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2012″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2012″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Anterior limb of the internal capsule in schizotypal personality disorder: fiber-tract counting, volume, and anisotropy<\/a><\/strong>
Hazlett EA, Collazo T, Zelmanova Y, Entis JJ, Chu KW, Goldstein KE,\u00a0Roussos P<\/span>, Haznedar MM, Koenigsberg HW, New AS, Buchsbaum MS, Hershowitz JP, Siever LJ, Byne W.
Schizophr Res. 2012 Nov;141(2-3):119-27. doi: 10.1016\/j.schres. 2012.08.022. Epub 2012 Sep 18.\u00a0<\/em>PMID: 22995934<\/p>\n

CACNA1C as a risk factor for schizotypal personality disorder and schizotypy in healthy individuals<\/strong><\/a>
Roussos P<\/span>, Bitsios P, Giakoumaki SG, McClure MM, Hazlett EA, New AS, Siever LJ.
Psychiatry Res. 2013 Mar 30;206(1):122-3. doi: 10.1016\/j.psychres. 2012.08.039. Epub 2012 Sep 15. No abstract available.\u00a0<\/em>PMID: 22985546<\/p>\n

Schizotypal personality disorder<\/strong><\/a>
Chemerinski E, Triebwasser J,\u00a0Roussos P<\/span>, Siever LJ.
J Pers Disord. 2013 Oct;27(5):652-79. doi: 10.1521\/pedi_ 2012_26_053. Epub 2012 Aug 28.\u00a0<\/em>PMID: 22928856<\/p>\n

Paranoid personality disorder<\/a><\/strong>
Triebwasser J, Chemerinski E,\u00a0Roussos P<\/span>, Siever LJ.
J Pers Disord. 2013 Dec;27(6):795-805. doi: 10.1521\/pedi_ 2012_26_055. Epub 2012 Aug 28. Review.\u00a0<\/em>PMID: 22928850<\/p>\n

A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples<\/strong><\/a>
Roussos P<\/span>, Katsel P, Davis KL, Siever LJ, Haroutunian V.
Arch Gen Psychiatry. 2012 Dec;69(12):1205-13. doi: 10.1001\/ archgenpsychiatry.2012.704.\u00a0<\/em>PMID: 22868662<\/p>\n

Cannabis-dependence risk relates to synergism between neuroticism and proenkephalin SNPs associated with amygdala gene expression: case-control study<\/a><\/strong>
Jutras-Aswad D, Jacobs MM, Yiannoulos G,\u00a0Roussos P<\/span>, Bitsios P, Nomura Y, Liu X, Hurd YL.
PLoS One. 2012;7(6):e39243. doi: 10.1371\/journal.pone.0039243. Epub 2012 Jun 22.\u00a0<\/em>PMID:22745721<\/p>\n

Transcription factor 4 as an important determinant of gating function in schizophrenia<\/a><\/strong>
Roussos P<\/span>.
Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):5915-6. doi:10.1073\/pnas. 1203675109. Epub 2012 Apr 5. No abstract available.\u00a0<\/em>PMID: 22492968<\/p>\n

Molecular and genetic evidence for abnormalities in the nodes of Ranvier in schizophrenia<\/a><\/strong>
Roussos P<\/span>, Katsel P, Davis KL, Bitsios P, Giakoumaki SG, Jogia J, Rozsnyai K, Collier D, Frangou S, Siever LJ, Haroutunian V.
Arch Gen Psychiatry. 2012 Jan;69(1):7-15. doi: 10.1001\/archgenpsychiatry. 2011.110. Epub 2011 Sep 5.\u00a0<\/em>PMID: 21893642<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2011″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2011″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Sustained attention and working memory deficits follow a familial pattern in schizophrenia<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Pallis EG, Bitsios P.
Arch Clin Neuropsychol. 2011 Nov;26(7):687-95. doi: 10.1093\/arclin\/acr060. Epub 2011 Aug 3.\u00a0<\/em>PMID: 21813556<\/p>\n

The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Georgakopoulos A, Robakis NK, Bitsios P.
Bipolar Disord. 2011 May;13(3):250-9. doi: 10.1111\/j.1399-5618. 2011.00924.x.\u00a0<\/em>PMID: 21676128<\/p>\n

Tolcapone, COMT polymorphisms and pharmacogenomic treatment of schizophrenia<\/a><\/strong>
Bitsios P,\u00a0Roussos P<\/strong>.
Pharmacogenomics. 2011 Apr;12(4):559-66. doi: 10.2217\/pgs.10.206\u00a0<\/em>PMID: 21521027<\/p>\n

The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Adamaki E, Georgakopoulos A, Robakis NK, Bitsios P.
Neuropsychopharmacology. 2011 Jul;36(8):1677-88. doi: 10.1038\/npp.2011.49. Epub 2011 Apr 6. Erratum in: Neuropsychopharmacology. 2011 Oct;36(11):2370. Anastasios, Georgakopoulos [corrected to Georgakopoulos, Anastasios]; Nikos, Robakis K [corrected to Robakis, Nikos K].\u00a0<\/em>PMID: 21471957<\/p>\n

Astrocyte and glutamate markers in the superficial, deep, and white matter layers of the anterior cingulate gyrus in schizophrenia<\/a><\/strong>
Katsel P, Byne W,\u00a0Roussos P<\/strong>, Tan W, Siever L, Haroutunian V.
Neuropsychopharmacology. 2011 May;36(6):1171-7. doi: 10.1038\/npp.2010.252. Epub 2011 Jan 26.\u00a0<\/em>PMID: 21270770<\/p>\n

The influence of schizophrenia-related neuregulin-1 polymorphisms on sensorimotor gating in healthy males<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Adamaki E, Bitsios P.
Biol Psychiatry. 2011 Mar 1;69(5):479-86. doi: 10.1016\/j.biopsych. 2010.09.009. Epub 2010 Oct 30.\u00a0<\/em>PMID: 21035784<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2010″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2010″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Cognitive and emotional processing associated with the Season of Birth and dopamine D4 receptor gene<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Neuropsychologia. 2010 Nov;48(13):3926-33. doi: 10.1016\/j.neuropsychologia. 2010.09.021. Epub 2010 Sep 25.\u00a0<\/em>PMID: 20875435<\/p>\n

Low baseline startle and deficient affective startle modulation in remitted bipolar disorder patients and their unaffected siblings<\/a><\/strong>
Giakoumaki SG, Bitsios P, Frangou S,\u00a0Roussos P<\/strong>, Aasen I, Galea A, Kumari V.
Psychophysiology. 2010 Jul 1;47(4):659-68. doi: 10.1111\/j.1469- 8986.2010.00977.x. Epub 2010 Mar 11.\u00a0<\/em>PMID: 20233338<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2009″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2009″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c\/g polymorphism<\/strong><\/a>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Biol Psychiatry. 2009 Dec 1;66(11):997-1004. doi: 10.1016\/j.biopsych.2009.07.008. Epub 2009 Aug 22.\u00a0<\/em>PMID: 19699472<\/p>\n

Cognitive and emotional processing in high novelty seeking associated with the L-DRD4 genotype<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Neuropsychologia. 2009 Jun;47(7):1654-9. doi: 10.1016\/ j.neuropsychologia.2009.02.005.Epub 2009 Feb 11.<\/em>PMID: 19397860<\/p>\n

Comparison of ketanserin, buspirone and propranolol on arousal, pupil size and autonomic function in healthy volunteers<\/a><\/strong>
Koudas V, Nikolaou A, Hourdaki E, Giakoumaki SG,\u00a0Roussos P<\/strong>, Bitsios P.
Psychopharmacology (Berl). 2009 Jul;205(1):1-9. doi: 10.1007\/s00213-009-1508-5. Epub 2009 Mar 14.\u00a0<\/em>PMID: 19288084<\/p>\n

A risk PRODH haplotype affects sensorimotor gating, memory, schizotypy, and anxiety in healthy male subjects<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Biol Psychiatry. 2009 Jun 15;65(12):1063-70. doi: 10.1016\/ j.biopsych.2009.01.003. Epub 2009 Feb 20.\u00a0<\/em>PMID: 19232576<\/p>\n

Azoles and antidepressants: a mini-review of the tolerability of co-administration<\/a><\/strong>
Roussos P<\/strong>, Lewis RE, Kontoyiannis DP.
Mycoses. 2009 Sep;52(5):433-9. doi: 10.1111\/j.1439-0507.2008. 01677.x. Epub 2009 Jan 21. Review.\u00a0<\/em>PMID: 19207836<\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”2008″ icon_color=”#00aeef” disabled_on=”off|off|off” admin_label=”2008″ _builder_version=”4.9.0″ title_text_color=”#00a6e5″ body_text_color=”#555555″ border_radii=”on|6px|6px|6px|6px” border_color_all=”#00aeef” saved_tabs=”all”]<\/p>\n

Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Bitsios P.
Neuropsychopharmacology. 2008 Dec;33(13):3058-68. doi: 10.1038\/npp.2008.82. Epub 2008 Jun 4.\u00a0<\/em>PMID: 18536698<\/p>\n

The dopamine D(3) receptor Ser9Gly polymorphism modulates prepulse inhibition of the acoustic startle reflex<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Biol Psychiatry. 2008 Aug 1;64(3):235-40. doi: 10.1016\/j.biopsych. 2008.01.020. Epub 2008 Mar 5.\u00a0<\/em>PMID: 18325483<\/p>\n

Prepulse inhibition of the startle reflex depends on the catechol O-methyltransferase Val158Met gene polymorphism<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Rogdaki M, Pavlakis S, Frangou S, Bitsios P.
Psychol Med. 2008 Nov;38(11):1651-8. doi: 10.1017\/ S0033291708002912. Epub 2008 Feb 8.\u00a0<\/em>PMID: 18261249<\/p>\n

Planning, decision-making and the COMT rs4818 polymorphism in healthy males<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Pavlakis S, Bitsios P.
Neuropsychologia. 2008 Jan 31;46(2):757-63. Epub 2007 Oct 22.\u00a0<\/em>PMID: 18037454<\/p>\n

The 5-min pupillary alertness test is sensitive to modafinil: a placebo controlled study in patients with sleep apnea<\/a><\/strong>
Nikolaou A, Schiza SE, Giakoumaki SG,\u00a0Roussos P<\/strong>, Siafakas N, Bitsios P.
Psychopharmacology (Berl). 2008 Feb;196(2):167-75. Epub 2007 Sep 25.\u00a0<\/em>PMID: 17899016<\/p>\n

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Disruption of prepulse inhibition of the startle reflex by the preferential D(3) agonist ropinirole in healthy males<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Frangou S, Bitsios P.
Psychopharmacology (Berl). 2007 Oct;194(3):289-95. Epub 2007 Jun 20.\u00a0<\/em>PMID: 17579840<\/p>\n

Evidence of disrupted prepulse inhibition in unaffected siblings of bipolar disorder patients<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Rogdaki M, Karli C, Bitsios P, Frangou S.
Biol Psychiatry. 2007 Dec 15;62(12):1418-22. Epub 2007 May 3.\u00a0<\/em>PMID: 17481589<\/p>\n

[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders. Ma Y, Bendl J,\u00a0Hartley BJ,\u00a0Fullard JF,\u00a0Abdelaal R, Ho SM,\u00a0Kosoy R,\u00a0Gochman P, Rapoport J,\u00a0Hoffman GE, Brennand KJ,\u00a0Roussos P.\u00a0Biol Psychiatry. 2024 Jan 15. doi: 10.1016\/j.biopsych.2023.07.003. Epub 2023 Jul 14. PMID: 37454787\u00a0 QuadST: A Powerful and Robust Approach for Identifying Cell-Cell Interaction-Changed Genes on Spatially […]<\/p>\n","protected":false},"author":223,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"

[et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.9.0\" custom_padding=\"0px|0px|0px|0\" disabled=\"on\"][et_pb_row _builder_version=\"3.25\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" _builder_version=\"4.9.0\"][et_pb_row _builder_version=\"4.9.0\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_toggle title=\"2023\" open=\"off\" closed_toggle_background_color=\"#eaeaea\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2021\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" border_radii=\"on|6px|6px|6px|6px\" border_width_all=\"0.5px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation.<\/a><\/strong><\/p>

Alldred MJ, Pidikiti H, Heguy A,\u00a0Roussos P<\/b>, Ginsberg SD.<\/span><\/div>
FASEB J. <\/span>2023 Jun;37(6):e22944. doi: 10.1096\/fj.202202111RR. <\/span><\/em>PMID:\u00a037191946<\/span><\/span><\/span><\/div>
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ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex.<\/a><\/strong><\/p>

Fulton SL, Bendl J,<\/strong> Gameiro-Ros I, Fullard JF<\/strong>, Al-Kachak A, Lepack AE, Stewart AF, Singh S, Poller WC, Bastle RM, Hauberg ME, Fakira AK, Chen M, Cuttoli RD, Cathomas F, Ramakrishnan A, Gleason K, Shen L, Tamminga CA, Milosevic A, Russo SJ, Swirski F, Blitzer RD, Slesinger PA,\u00a0Roussos P<\/b>, Maze I.<\/span><\/div>
bioRxiv. 2023 May 4:2023.05.04.539425. doi: 10.1101\/2023.05.04.539425. Preprint. <\/span><\/em>PMID:\u00a037205394<\/span><\/span><\/div>
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Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis.<\/a><\/strong><\/p>

Kiss MG, Mindur JE, Yates AG, Lee D, Fullard JF,<\/strong> Anzai A, Poller WC, Christie KA, Iwamoto Y, Roudko V, Downey J, Chan CT, Huynh P, Janssen H, Ntranos A, Hoffmann JD, Jacob W, Goswami S, Singh S, Leppert D, Kuhle J, Kim-Schulze S, Nahrendorf M, Kleinstiver BP, Probert F,\u00a0Roussos P<\/b>, Swirski FK, McAlpine CS. <\/span><\/div>
Immunity. 2023 May 2:S1074-7613(23)00177-2. doi: 10.1016\/j.immuni.2023.04.013. Online ahead of print.<\/em> <\/span>PMID:\u00a037160117<\/span><\/span><\/div><\/div>
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Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.<\/a><\/strong><\/div>
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Hsu YH, Pintacuda G, Liu R, Nacu E, Kim A, Tsafou K, Petrossian N, Crotty W, Suh JM, Riseman J, Martin JM, Biagini JC, Mena D, Ching JKT, Malolepsza E, Li T, Singh T, Ge T, Egri SB, Tanenbaum B, Stanclift CR, Apffel AM; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Stanley Global Asia Initiatives; Carr SA, Schenone M, Jaffe J, Fornelos N, Huang H, Eggan KC, Lage K. <\/span>iScience. 2023 Apr 18;26(5):106701. doi: 10.1016\/j.isci.2023.106701. eCollection 2023 May 19. <\/span><\/em>PMID:\u00a037207277<\/span><\/span><\/div><\/div>
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A study of gene expression in the living human brain.<\/a><\/strong><\/p>

Liharska LE, Park YJ, Ziafat K, Wilkins L, Silk H, Linares LM, Thompson RC, Vornholt E, Sullivan B, Cohen V, Kota P, Feng C, Cheng E, Johnson JS, Rieder MK, Huang J, Scarpa J, Polanco J, Moya E, Hashemi A, Bendl J, Hoffman GE,<\/strong>\u00a0Roussos P<\/b>, Levin MA, Nadkarni GN, Sebra R, Crary J, Sklar P, Schadt EE, Beckmann ND, Kopell BH, Charney AW. <\/span><\/div>
medRxiv. 2023 Apr 26:2023.04.21.23288916. doi: 10.1101\/2023.04.21.23288916. Preprint. <\/span><\/em>PMID:\u00a037163086<\/span><\/span><\/div>
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Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases.<\/a><\/strong><\/p>

Zeng B, Bendl J, Deng C,<\/strong> Lee D<\/strong>, Misir R, Reach SM, Kleopoulos SP<\/strong>, Auluck P, Marenco S, Lewis DA, Haroutunian V, Ahituv N, Fullard JF, Hoffman GE,<\/strong>\u00a0Roussos P. <\/b><\/span><\/div>
bioRxiv. 2023 Mar 2:2023.03.02.530826. doi: 10.1101\/2023.03.02.530826. Preprint. <\/span><\/em>PMID:\u00a037090548<\/span><\/span><\/div>
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Applications of artificial intelligence-machine learning for detection of stress: a critical overview.<\/a><\/strong><\/p>

Mentis AA, Lee D,<\/strong>\u00a0Roussos P. <\/b><\/span><\/div>
Mol Psychiatry. 2023 Apr 5. doi: 10.1038\/s41380-023-02047-6. Online ahead of print.<\/em> <\/span>PMID:\u00a037020048<\/span><\/span><\/div>
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Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data.<\/a><\/strong><\/p>

Dai R, Chu T, Zhang M, Wang X, Jourdon A, Wu F, Mariani J, Vaccarino FM, Lee D, Fullard JF, Hoffman GE<\/strong>,\u00a0Roussos P<\/b>, Wang Y, Wang X, Pinto D, Wang SH, Zhang C; PsychENCODE consortium; Chen C, Liu C.<\/span><\/div>
bioRxiv. 2023 Mar 15:2023.03.13.532468. doi: 10.1101\/2023.03.13.532468. Preprint.<\/em> <\/span>PMID:\u00a036993743<\/span><\/span><\/div>

Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet.<\/a><\/strong><\/p>

Hoffman GE, Lee D, Bendl J, Fnu P, Hong A, Casey C<\/strong>, Alvia M, Shao Z, Argyriou S, Therrien K, Venkatesh S, Voloudakis G, Haroutunian V, Fullard JF,\u00a0Roussos P. <\/b><\/span><\/div>
bioRxiv. 2023 Mar 20:2023.03.17.533005. doi: 10.1101\/2023.03.17.533005. Preprint.<\/em> <\/span>PMID:\u00a036993704<\/span><\/span><\/div>

Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations.<\/strong><\/a><\/p>

Liu D, Meyer D, Fennessy B, Feng C, Cheng E, Johnson JS, Park YJ, Rieder MK, Ascolillo S, de Pins A, Dobbyn A, Lebovitch D, Moya E, Nguyen TH, Wilkins L, Hassan A; Psychiatric Genomics Consortium Phase 3 Targeted Sequencing of Schizophrenia Study Team; Burdick KE, Buxbaum JD, Domenici E, Frangou S, Hartmann AM, Laurent-Levinson C, Malhotra D, Pato CN, Pato MT, Ressler K, Roussos P<\/strong>, Rujescu D, Arango C, Bertolino A, Blasi G, Bocchio-Chiavetto L, Campion D, Carr V, Fullerton JM, Gennarelli M, Gonz\u00e1lez-Pe\u00f1as J, Levinson DF, Mowry B, Nimgaokar VL, Pergola G, Rampino A, Cervilla JA, Rivera M, Schwab SG, Wildenauer DB, Daly M, Neale B, Singh T, O'Donovan MC, Owen MJ, Walters JT, Ayub M, Malhotra AK, Lencz T, Sullivan PF, Sklar P, Stahl EA, Huckins LM, Charney AW.\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 Nat Genet. 2023 Mar;55(3):369-376. doi: 10.1038\/s41588-023-01305-1. Epub 2023 Mar 13.<\/em> PMID: 36914870<\/p>

Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease.<\/strong><\/a><\/p>

Wang E, Wang M, Guo L, Fullard JF, Micallef C, Bendl J<\/strong>, Song WM, Ming C, Huang Y, Li Y, Yu K, Peng J, Bennett DA, De Jager PL, Roussos P<\/strong>, Haroutunian V, Zhang B.
Alzheimers Dement. 2023 Feb 22. doi: 10.1002\/alz.12969. Online ahead of print.<\/em> PMID: 36811307<\/p>

Detecting and Adjusting for Hidden Biases due to Phenotype Misclassification in Genome-Wide Association Studies.<\/strong><\/a><\/p>

Burstein D, Hoffman G, Mathur D, Venkatesh S, Therrien K<\/strong>, Fanous AH, Bigdeli TB, Harvey PD, Roussos P<\/strong>, Voloudakis G. medRxiv. 2023 Jan 18:2023.01.17.23284670. doi: 10.1101\/2023.01.17.23284670. Preprint. <\/span><\/em>PMID:\u00a036711948<\/span><\/span><\/p>

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.<\/strong><\/a><\/p>

Demontis D, Walters GB, Athanasiadis G, Walters R, Therrien K<\/strong>, Nielsen TT, Farajzadeh L, Voloudakis G, Bendl J<\/strong>, Zeng B, Zhang W, Grove J, Als TD, Duan J, Satterstrom FK, Bybjerg-Grauholm J, B\u00e6kved-Hansen M, Gudmundsson OO, Magnusson SH, Baldursson G, Davidsdottir K, Haraldsdottir GS, Agerbo E, Hoffman GE, Dalsgaard S, Martin J, Ribas\u00e9s M, Boomsma DI, Soler Artigas M, Roth Mota N, Howrigan D, Medland SE, Zayats T, Rajagopal VM; ADHD Working Group of the Psychiatric Genomics Consortium; iPSYCH-Broad Consortium; Nordentoft M, Mors O, Hougaard DM, Mortensen PB, Daly MJ, Faraone SV, Stefansson H, Roussos P<\/strong>, Franke B, Werge T, Neale BM, Stefansson K, B\u00f8rglum AD. Nat Genet. 2023 Feb;55(2):198-208. doi: 10.1038\/s41588-022-01285-8. Epub 2023 Jan 26. <\/span><\/em>PMID:\u00a036702997<\/span><\/span><\/p>

Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity.<\/strong><\/a><\/p>

Rajagopal VM, Ganna A, Coleman JRI, Allegrini A, Voloudakis G, Grove J, Als TD, Horsdal HT, Petersen L, Appadurai V, Schork A, Buil A, Bulik CM, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Hougaard DM, Mors O, Nordentoft M, Werge T; iPSYCH-Broad Consortium; Mortensen PB, Breen G, Roussos P<\/strong>, Plomin R, Agerbo E, B\u00f8rglum AD, Demontis D. Sci Rep. 2023 Jan 9;13(1):429. doi: 10.1038\/s41598-022-26845-0. <\/span><\/em>PMID:\u00a036624241<\/span><\/span><\/p>

African ancestry GWAS of dementia in a large military cohort identifies significant risk loci.<\/strong><\/a><\/p>

Sherva R, Zhang R, Sahelijo N, Jun G, Anglin T, Chanfreau C, Cho K, Fonda JR, Gaziano JM, Harrington KM, Ho YL, Kremen WS, Litkowski E, Lynch J, Neale Z, Roussos P<\/strong>, Marra D, Mez J, Miller MW, Salat DH, Tsuang D, Wolf E, Zeng Q, Panizzon MS, Merritt VC, Farrer LA, Hauger RL, Logue MW. Mol Psychiatry. 2023 Mar;28(3):1293-1302. doi: 10.1038\/s41380-022-01890-3. Epub 2022 Dec 22. <\/span><\/em>PMID:\u00a036543923<\/span><\/span><\/p>

Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae.<\/a><\/strong><\/p>

Thompson RC, Simons NW, Wilkins L, Cheng E, Del Valle DM, Hoffman GE, Cervia C, Fennessy B, Mouskas K, Francoeur NJ, Johnson JS, Lepow L, Le Berichel J, Chang C, Beckmann AG, Wang YC, Nie K, Zaki N, Tuballes K, Barcessat V, Cedillo MA, Yuan D, Huckins L, Roussos P<\/strong>, Marron TU; Mount Sinai COVID-19 Biobank Team; Glicksberg BS, Nadkarni G, Heath JR, Gonzalez-Kozlova E, Boyman O, Kim-Schulze S, Sebra R, Merad M, Gnjatic S, Schadt EE, Charney AW, Beckmann ND. Nat Med. 2023 Jan;29(1):236-246. doi: 10.1038\/s41591-022-02107-4. Epub 2022 Dec 8.<\/em> <\/span>PMID:\u00a036482101<\/span><\/span><\/p>

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.<\/a><\/strong><\/p>

Fulton SL, Wenderski W, Lepack AE, Eagle AL, Fanutza T, Bastle RM, Ramakrishnan A, Hays EC, Neal A, Bendl J<\/strong>, Farrelly LA, Al-Kachak A, Lyu Y, Cetin B, Chan JC, Tran TN, Neve RL, Roper RJ, Brennand KJ,\u00a0Roussos P<\/b>, Schimenti JC, Friedman AK, Shen L, Blitzer RD, Robison AJ, Crabtree GR, Maze I.<\/span><\/div>
Nat Commun. 2022 Oct 26;13(1):6384. doi: 10.1038\/s41467-022-34200-0.<\/em> <\/span>PMID:\u00a036289231<\/span><\/span><\/div>

A mechanistic framework for cardiometabolic and coronary artery diseases.<\/strong><\/a><\/p>

Koplev S, Seldin M, Sukhavasi K, Ermel R, Pang S, Zeng L, Bankier S, Di Narzo A, Cheng H, Meda V, Ma A, Talukdar H, Cohain A, Amadori L, Argmann C, Houten SM, Franz\u00e9n O, Mocci G, Meelu OA, Ishikawa K, Whatling C, Jain A, Jain RK, Gan LM, Giannarelli C,\u00a0Roussos P<\/b>, Hao K, Schunkert H, Michoel T, Ruusalepp A, Schadt EE, Kovacic JC, Lusis AJ, Bj\u00f6rkegren JLM.<\/span><\/p>

Nat Cardiovasc Res. 2022 Jan;1(1):85-100. doi: 10.1038\/s44161-021-00009-1. Epub 2022 Jan 12. <\/span><\/em>PMID:\u00a036276926<\/span><\/span><\/p>

[et_pb_section fb_built=\"1\" disabled_on=\"on|on|on\" _builder_version=\"4.9.0\" custom_padding=\"0px|0px|0px|0\" disabled=\"on\"][et_pb_row _builder_version=\"3.25\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" _builder_version=\"4.9.0\"][et_pb_row _builder_version=\"4.9.0\" background_size=\"initial\" background_position=\"top_left\" background_repeat=\"repeat\"][et_pb_column type=\"4_4\" _builder_version=\"3.0.47\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_toggle title=\"2022\" open=\"off\" closed_toggle_background_color=\"#eaeaea\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2021\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" border_radii=\"on|6px|6px|6px|6px\" border_width_all=\"0.5px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.<\/strong><\/a><\/p>

Carcamo-Orive I, Hoffman GE<\/strong>, Cundiff P, Beckmann ND, D'Souza SL, Knowles JW, Patel A, Hendry C, Papatsenko D, Abbasi F, Reaven GM, Whalen S, Lee P, Shahbazi M, Henrion MYR, Zhu K, Wang S,\u00a0Roussos P<\/b>, Schadt EE, Pandey G, Chang R, Quertermous T, Lemischka I.<\/span>Cell Stem Cell. 2022 Oct 6;29(10):1505. doi: 10.1016\/j.stem.2022.08.011.<\/span>PMID:\u00a036206733<\/span><\/span><\/p>

The three-dimensional landscape of cortical chromatin accessibility in Alzheimer's disease.<\/strong><\/a><\/p>

Bendl J<\/strong>, Hauberg ME, Girdhar K<\/strong>, Im E, Vicari JM, Rahman S,<\/strong> Fernando MB, Townsley KG, Dong P<\/strong>, Misir R, Kleopoulos SP<\/strong>, Reach SM, Apontes P, Zeng<\/strong> B<\/strong>, Zhang W, Voloudakis G<\/strong>, Brennand KJ, Nixon RA, Haroutunian V, Hoffman GE, Fullard JF<\/strong>,\u00a0Roussos P.<\/b><\/span>Nat Neurosci. 2022 Oct;25(10):1366-1378. doi: 10.1038\/s41593-022-01166-7. Epub 2022 Sep 28.<\/span>PMID:\u00a036171428<\/span><\/span><\/p>

Population-level variation in enhancer expression identifies disease mechanisms in the human brain.<\/strong><\/a><\/p>

Dong P, Hoffman GE,<\/strong> Apontes P, Bendl J, Rahman S<\/strong>, Fernando MB, Zeng B<\/strong>, Vicari JM,<\/strong> Zhang W, Girdhar K<\/strong>, Townsley KG, Misir R; CommonMind Consortium, Brennand KJ, Haroutunian V, Voloudakis G<\/strong>, Fullard JF<\/strong>,\u00a0Roussos P.<\/b><\/span>Nat Genet. 2022 Oct;54(10):1493-1503. doi: 10.1038\/s41588-022-01170-4. Epub 2022 Sep 26.<\/span>PMID:\u00a036163279<\/span><\/span><\/p>

Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups.<\/strong><\/a><\/p>

Mattheisen M, Grove J, Als TD, Martin J, Voloudakis G<\/strong>, Meier S, Demontis D, Bendl J,<\/strong> Walters R, Carey CE, Rosengren A, Strom NI, Hauberg ME, Zeng B<\/strong>, Hoffman G<\/strong>, Zhang W, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Agerbo E, Cormand B, Nordentoft M, Werge T, Mors O, Hougaard DM, Buxbaum JD, Faraone SV, Franke B, Dalsgaard S, Mortensen PB, Robinson EB,\u00a0Roussos P<\/b>, Neale BM, Daly MJ, B\u00f8rglum AD.<\/span>Nat Genet. 2022 Oct;54(10):1470-1478. doi: 10.1038\/s41588-022-01171-3. Epub 2022 Sep 26.<\/span>PMID:\u00a036163277<\/span><\/span><\/p>

Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review.<\/strong><\/a><\/p>

Hoffman GE<\/strong>, Jaffe AE, Gandal MJ, Collado-Torres L, Sieberts SK, Devlin B, Geschwind DH, Weinberger DR,\u00a0Roussos P. <\/b><\/span>Mol Psychiatry. 2022 Sep 19. doi: 10.1038\/s41380-022-01781-7. Online ahead of print.<\/span>PMID:\u00a036123423<\/span><\/span><\/p>

Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia, Bipolar Disorder, and Depression Among Adults in the US Veterans Affairs Health Care System.<\/strong><\/a><\/p>

Bigdeli TB, Voloudakis G<\/strong>, Barr PB, Gorman BR, Genovese G, Peterson RE, Burstein DE<\/strong>, Velicu VI, Li Y, Gupta R, Mattheisen M, Tomasi S, Rajeevan N, Sayward F, Radhakrishnan K, Natarajan S, Malhotra AK, Shi Y, Zhao H, Kosten TR, Concato J, O'Leary TJ, Przygodzki R, Gleason T, Pyarajan S, Brophy M, Huang GD, Muralidhar S, Gaziano JM, Aslan M, Fanous AH, Harvey PD,\u00a0Roussos P<\/b>; Cooperative Studies Program (CSP) #572 and Million Veteran Program (MVP).<\/span>JAMA Psychiatry. 2022 Sep 14:e222742. doi: 10.1001\/jamapsychiatry.2022.2742. Online ahead of print.<\/span>PMID:\u00a036103194<\/span><\/span><\/p>

A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility.<\/strong><\/a><\/p>

Voloudakis G, Vicari JM, Venkatesh S, Hoffman GE<\/strong>, Dobrindt K, Zhang W, Beckmann ND, Higgins CA, Argyriou S, Jiang S, Hoagland D, Gao L, Corvelo A, Cho K, Lee KM, Bian J, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Lynch JA, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative, Brennand KJ, Fullard JF<\/strong>,\u00a0Roussos P.<\/b><\/span>NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038\/s41525-022-00324-x.<\/span>PMID:\u00a036064543<\/span><\/span><\/p>

Genetics of the human microglia regulome refines Alzheimer's disease risk loci.<\/strong><\/a><\/p>

Kosoy R, Fullard JF, Zeng B, Bendl J, Dong P, Rahman S, Kleopoulos SP, Shao Z, Girdhar K,<\/strong> Humphrey J, de Paiva Lopes K, Charney AW, Kopell BH, Raj T, Bennett D, Kellner CP, Haroutunian V, Hoffman GE,<\/strong>\u00a0Roussos P.<\/b><\/span>Nat Genet. 2022 Aug;54(8):1145-1154. doi: 10.1038\/s41588-022-01149-1. Epub 2022 Aug 5.<\/span>PMID:\u00a035931864<\/span><\/span><\/p>

The Neuroepigenome: Implications of Chemical and Physical Modifications of Genomic DNA in Schizophrenia.<\/strong><\/a><\/p>

Girdhar K, Rahman S, Dong P, Fullard JF,<\/strong>\u00a0Roussos P.<\/b><\/span>Biol Psychiatry. 2022 Sep 15;92(6):443-449. doi: 10.1016\/j.biopsych.2022.04.018. Epub 2022 May 10.<\/span>PMID:\u00a035750513<\/span><\/span><\/p>

Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development.<\/strong><\/a><\/p>

Liu D, Zinski A, Mishra A, Noh H, Park GH, Qin Y, Olorife O, Park JM, Abani CP, Park JS, Fung J, Sawaqed F, Coyle JT, Stahl E, Bendl J, Fullard JF,<\/strong>\u00a0Roussos P<\/b>, Zhang X, Stanton PK, Yin C, Huang W, Kim HY, Won H, Cho JH, Chung S. Mol Psychiatry. 2022 Jun 14. doi: 10.1038\/s41380-022-01654-z. Online ahead of print.<\/span>PMID:\u00a035701597<\/span><\/span><\/p>

Mapping genomic loci implicates genes and synaptic biology in schizophrenia.<\/strong><\/a><\/p>

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A complete temporal transcription factor series in the fly visual system.<\/strong><\/a><\/p>

Konstantinides N, Holguera I, Rossi AM, Escobar A, Dudragne L, Chen YC, Tran TN, Mart\u00ednez Jaimes AM, \u00d6zel MN, Simon F, Shao Z<\/strong>, Tsankova NM, Fullard JF,<\/strong> Walldorf U,\u00a0Roussos P<\/b>, Desplan C.<\/span>Nature. 2022 Apr;604(7905):316-322. doi: 10.1038\/s41586-022-04564-w. Epub 2022 Apr 6.<\/span>PMID:\u00a035388222<\/span><\/span><\/p>

Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains.<\/strong><\/a><\/p>

Girdhar K, Hoffman GE, Bendl J, Rahman S, Dong P,<\/strong> Liao W, Hauberg ME, Sloofman L, Brown L, Devillers O, Kassim BS, Wiseman JR, Park R, Zharovsky E, Jacobov R, Flatow E, Kozlenkov A, Gilgenast T, Johnson JS, Couto L, Peters MA, Phillips-Cremins JE, Hahn CG, Gur RE, Tamminga CA, Lewis DA, Haroutunian V; PsychENCODE Consortium, Dracheva S, Lipska BK, Marenco S, Kundakovic M, Fullard JF<\/strong>, Jiang Y,\u00a0Roussos P<\/b>, Akbarian S.<\/span>Nat Neurosci. 2022 Apr;25(4):474-483. doi: 10.1038\/s41593-022-01032-6. Epub 2022 Mar 24.<\/span>PMID:\u00a035332326<\/span><\/span><\/p>

Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia.<\/strong><\/a><\/p>

Zazhytska M, Kodra A, Hoagland DA, Frere J, Fullard JF<\/strong>, Shayya H, McArthur NG, Moeller R, Uhl S, Omer AD, Gottesman ME, Firestein S, Gong Q, Canoll PD, Goldman JE,\u00a0Roussos P<\/b>, tenOever BR, Jonathan B Overdevest, Lomvardas S.<\/span>Cell. 2022 Mar 17;185(6):1052-1064.e12. doi: 10.1016\/j.cell.2022.01.024. Epub 2022 Feb 2.<\/span>PMID:\u00a035180380<\/span><\/span><\/p>

Altered gene expression and PTSD symptom dimensions in World Trade Center responders.<\/strong><\/a><\/p>

Marchese S, Cancelmo L, Diab O, Cahn L, Aaronson C, Daskalakis NP, Schaffer J, Horn SR, Johnson JS, Schechter C, Desarnaud F, Bierer LM, Makotkine I, Flory JD, Crane M, Moline JM, Udasin IG, Harrison DJ,\u00a0Roussos P<\/b>, Charney DS, Koenen KC, Southwick SM, Yehuda R, Pietrzak RH, Huckins LM, Feder A.<\/span>Mol Psychiatry. 2022 Apr;27(4):2225-2246. doi: 10.1038\/s41380-022-01457-2. Epub 2022 Feb 17.<\/span>PMID:\u00a035177824<\/span><\/span><\/p>

Transcriptome-wide association study in UK Biobank Europeans identifies associations with blood cell traits<\/strong>.<\/a><\/p>

Rowland B, Venkatesh S, Tardaguila M, Wen J, Rosen JD, Tapia AL, Sun Q, Graff M, Vuckovic D, Lettre G, Sankaran VG, Voloudakis G,<\/strong>\u00a0Roussos P<\/b>, Huffman JE, Reiner AP, Soranzo N, Raffield LM, Li Y.<\/span>Hum Mol Genet. 2022 Jul 21;31(14):2333-2347. doi: 10.1093\/hmg\/ddac011.<\/span>PMID:\u00a035138379<\/span><\/span><\/p>

Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits.<\/strong><\/a><\/p>

Zeng B, Bendl J<\/strong>, Kosoy R, Fullard JF, Hoffman GE,<\/strong>\u00a0Roussos P. <\/b><\/span>Nat Genet. 2022 Feb;54(2):161-169. doi: 10.1038\/s41588-021-00987-9. Epub 2022 Jan 20.<\/span>PMID:\u00a035058635<\/span><\/span><\/p>

A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning.<\/strong><\/a><\/p>

Hafez AK, Zimmerman AJ, Papageorgiou G, Chandrasekaran J, Amoah SK, Lin R, Lozano E, Pierotti C, Dell'Orco M, Hartley BJ, Alural B, Lalonde J, Esposito JM, Berretta S, Squassina A, Chillotti C, Voloudakis G<\/strong>, Shao Z, Fullard JF<\/strong>, Brennand KJ, Turecki G, Roussos P<\/strong>,\u00a0Perlis RH, Haggarty SJ, Perrone-Bizzozero N, Brigman JL, Mellios N.
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Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.<\/strong><\/a><\/p>

Pardi\u00f1as AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P, Wu JQ, Andreassen OA, Kowalec K, Sullivan PF, Murray RM, Owen MJ, MacCabe JH, O'Donovan MC, Walters JTR; Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances (STRATA) Consortium and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC)<\/strong>, Ajnakina O, Alameda L, Barnes TRE, Berardi D, Bonora E, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Do KQ, Doody GA, Eap CB, Ferchiou A, Di Forti M, Guidi L, Homman L, Jenni R, Joyce EM, Kassoumeri L, Khadimallah I, Lastrina O, Muratori R, Noyan H, O'Neill FA, Pignon B, Restellini R, Richard JR, Sch\u00fcrhoff F, \u0160paniel F, Sz\u00f6ke A, Tarricone I, Tortelli A, \u00dc\u00e7ok A, V\u00e1zquez-Bourgon J.<\/span>JAMA Psychiatry. 2022 Mar 1;79(3):260-269. doi: 10.1001\/jamapsychiatry.2021.3799.<\/span>PMID:\u00a035019943<\/span><\/span><\/p>

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Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.<\/strong><\/a><\/p>

Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, Hafferty JD, Hishimoto A, Kim M, Okazaki S, Otsuka I, Ripke S, Ware EB, Bergen AW, Berrettini WH, Bohus M, Brandt H, Chang X, Chen WJ, Chen HC, Crawford S, Crow S, DiBlasi E, Duriez P, Fern\u00e1ndez-Aranda F, Fichter MM, Gallinger S, Glatt SJ, Gorwood P, Guo Y, Hakonarson H, Halmi KA, Hwu HG, Jain S, Jamain S, Jim\u00e9nez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Klump KL, Li D, Liao SC, Lieb K, Lilenfeld L, Liu CM, Magistretti PJ, Marshall CR, Mitchell JE, Monson ET, Myers RM, Pinto D, Powers A, Ramoz N, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Strober M, Thornton LM, Treasure J, Tsuang MT, Witt SH, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Air TM, Alda M, Alfredsson L, Andreassen OA, Anjorin A, Appadurai V, Soler Artigas M, Van der Auwera S, Azevedo MH, Bass N, Bau CHD, Baune BT, Bellivier F, Berger K, Biernacka JM, Bigdeli TB, Binder EB, Boehnke M, Boks MP, Bosch R, Braff DL, Bryant R, Budde M, Byrne EM, Cahn W, Casas M, Castelao E, Cervilla JA, Chaumette B, Cichon S, Corvin A, Craddock N, Craig D, Degenhardt F, Djurovic S, Edenberg HJ, Fanous AH, Foo JC, Forstner AJ, Frye M, Fullerton JM, Gatt JM, Gejman PV, Giegling I, Grabe HJ, Green MJ, Grevet EH, Grigoroiu-Serbanescu M, Gutierrez B, Guzman-Parra J, Hamilton SP, Hamshere ML, Hartmann A, Hauser J, Heilmann-Heimbach S, Hoffmann P, Ising M, Jones I, Jones LA, Jonsson L, Kahn RS, Kelsoe JR, Kendler KS, Kloiber S, Koenen KC, Kogevinas M, Konte B, Krebs MO, Land\u00e9n M, Lawrence J, Leboyer M, Lee PH, Levinson DF, Liao C, Lissowska J, Lucae S, Mayoral F, McElroy SL, McGrath P, McGuffin P, McQuillin A, Medland SE, Mehta D, Melle I, Milaneschi Y, Mitchell PB, Molina E, Morken G, Mortensen PB, M\u00fcller-Myhsok B, Nievergelt C, Nimgaonkar V, N\u00f6then MM, O'Donovan MC, Ophoff RA, Owen MJ, Pato C, Pato MT, Penninx BWJH, Pimm J, Pistis G, Potash JB, Power RA, Preisig M, Quested D, Ramos-Quiroga JA, Reif A, Ribas\u00e9s M, Richarte V, Rietschel M, Rivera M, Roberts A, Roberts G, Rouleau GA, Rovaris DL, Rujescu D, S\u00e1nchez-Mora C, Sanders AR, Schofield PR, Schulze TG, Scott LJ, Serretti A, Shi J, Shyn SI, Sirignano L, Sklar P, Smeland OB, Smoller JW, Sonuga-Barke EJS, Spalletta G, Strauss JS, \u015awi\u0105tkowska B, Trzaskowski M, Turecki G, Vilar-Rib\u00f3 L, Vincent JB, V\u00f6lzke H, Walters JTR, Shannon Weickert C, Weickert TW, Weissman MM, Williams LM, Wray NR, Zai CC, Ashley-Koch AE, Beckham JC, Hauser ER, Hauser MA, Kimbrel NA, Lindquist JH, McMahon B, Oslin DW, Qin X; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>; Eating Disorders Working Group of the Psychiatric Genomics Consortium; German Borderline Genomics Consortium; MVP Suicide Exemplar Workgroup; VA Million Veteran Program, Agerbo E, B\u00f8rglum AD, Breen G, Erlangsen A, Esko T, Gelernter J, Hougaard DM, Kessler RC, Kranzler HR, Li QS, Martin NG, McIntosh AM, Mors O, Nordentoft M, Olsen CM, Porteous D, Ursano RJ, Wasserman D, Werge T, Whiteman DC, Bulik CM, Coon H, Demontis D, Docherty AR, Kuo PH, Lewis CM, Mann JJ, Renter\u00eda ME, Smith DJ, Stahl EA, Stein MB, Streit F, Willour V, Ruderfer DM.<\/span>Biol Psychiatry. 2022 Feb 1;91(3):313-327. doi: 10.1016\/j.biopsych.2021.05.029. Epub 2021 Sep 9.<\/span>PMID:\u00a034861974<\/span><\/span><\/p>

Correction to: Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer's Disease.<\/a><\/strong><\/p>

Alldred MJ, Penikalapati SC, Lee SH, Heguy A,\u00a0Roussos P<\/b>, Ginsberg SD.<\/span>Mol Neurobiol. 2022 Feb;59(2):1345-1346. doi: 10.1007\/s12035-021-02647-9.<\/span>PMID:\u00a034837629<\/span><\/span><\/p>

Engagement of vascular early response genes typifies mild cognitive impairment.<\/a><\/strong><\/p>

Katsel P, Fam P, Tan W, Khan S, Gama-Sosa M, De Gasperi R,\u00a0Roussos P<\/b>, Robinson A, Cooper I, Schnaider-Beeri M, Haroutunian V.<\/span>Alzheimers Dement. 2022 Jul;18(7):1357-1369. doi: 10.1002\/alz.12481. Epub 2021 Nov 10.<\/span>PMID:\u00a034758195<\/span><\/span><\/p>

Use of the PsycheMERGE Network to Investigate the Association Between Depression Polygenic Scores and White Blood Cell Count.<\/a><\/strong><\/p>

Sealock JM, Lee YH, Moscati A, Venkatesh S<\/strong>, Voloudakis G<\/strong>, Straub P, Singh K, Feng YA, Ge T,\u00a0Roussos P<\/b>, Smoller JW, Chen G, Davis LK. JAMA Psychiatry. 2021 Dec 1;78(12):1365-1374. doi: 10.1001\/jamapsychiatry.2021.2959.<\/span>PMID:\u00a034668925<\/span><\/span><\/span><\/p>

Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.<\/a><\/strong>
Cirnaru MD, Song S, Tshilenge KT, Corwin C, Mleczko J, Galicia Aguirre C, Benlhabib H, Bendl J, Apontes P, Fullard J<\/strong>, Creus-Muncunill J, Reyahi A, Nik AM, Carlsson P,\u00a0Roussos P<\/strong>, Mooney SD, Ellerby LM, Ehrlich ME. Elife. 2021 Oct 5;10:e65979. doi: 10.7554\/eLife.65979.<\/em>PMID:\u00a034609283<\/p>

Author Correction: Brain Cell Type Specific Gene Expression and Co-expression Network Architectures.<\/a><\/strong>
McKenzie AT, Wang M, Hauberg ME, Fullard JF<\/strong>, Kozlenkov A, Keenan A, Hurd YL, Dracheva S, Casaccia P,\u00a0Roussos P<\/strong>, Zhang B. Sci Rep. 2021 Sep 24;11(1):19430. doi: 10.1038\/s41598-021-97284-6.<\/em>PMID:\u00a034561470<\/p>

Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children.<\/a><\/strong>
Beckmann ND, Comella PH, Cheng E, Lepow L, Beckmann AG, Tyler SR, Mouskas K, Simons NW, Hoffman GE<\/strong>, Francoeur NJ, Del Valle DM, Kang G, Do A, Moya E, Wilkins L, Le Berichel J, Chang C, Marvin R, Calorossi S, Lansky A, Walker L, Yi N, Yu A, Chung J, Hartnett M, Eaton M, Hatem S, Jamal H, Akyatan A, Tabachnikova A, Liharska LE, Cotter L, Fennessy B, Vaid A, Barturen G, Shah H, Wang YC, Sridhar SH, Soto J, Bose S, Madrid K, Ellis E, Merzier E, Vlachos K, Fishman N, Tin M, Smith M, Xie H, Patel M, Nie K, Argueta K, Harris J, Karekar N, Batchelor C, Lacunza J, Yishak M, Tuballes K, Scott I, Kumar A, Jaladanki S, Agashe C, Thompson R, Clark E, Losic B, Peters L; Mount Sinai COVID-19 Biobank Team,\u00a0Roussos P<\/strong>, Zhu J, Wang W, Kasarskis A, Glicksberg BS, Nadkarni G, Bogunovic D, Elaiho C, Gangadharan S, Ofori-Amanfo G, Alesso-Carra K, Onel K, Wilson KM, Argmann C, Bunyavanich S, Alarc\u00f3n-Riquelme ME, Marron TU, Rahman A, Kim-Schulze S, Gnjatic S, Gelb BD, Merad M, Sebra R, Schadt EE, Charney AW. Nat Commun. 2021 Aug 11;12(1):4854. doi: 10.1038\/s41467-021-24981-1.<\/em>PMID:\u00a034381049<\/p>

Association between genes regulating neural pathways for quantitative traits of speech and language disorders.<\/a><\/strong>
Benchek P, Igo RP Jr, Voss-Hoynes H, Wren Y, Miller G, Truitt B, Zhang W, Osterman M, Freebairn L, Tag J, Taylor HG, Chan ER,\u00a0Roussos P<\/strong>, Lewis B, Stein CM, Iyengar SK. NPJ Genom Med. 2021 Jul 27;6(1):64. doi: 10.1038\/s41525-021-00225-5.<\/em>PMID:\u00a034315907<\/p>

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.<\/a><\/strong>
Ni G, Zeng J, Revez JA, Wang Y, Zheng Z, Ge T, Restuadi R, Kiewa J, Nyholt DR, Coleman JRI, Smoller JW; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>, Yang J, Visscher PM, Wray NR. Biol Psychiatry. 2021 Nov 1;90(9):611-620. doi: 10.1016\/j.biopsych.2021.04.018. Epub 2021 May 4.<\/em>PMID:\u00a034304866<\/p>

Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19. <\/a><\/strong>
Fullard JF, Lee HC, Voloudakis G<\/strong>, Suo S, Javidfar B, Shao Z<\/strong>, Peter C, Zhang W, Jiang S, Corvelo A, Wargnier H, Woodoff-Leith E, Purohit DP, Ahuja S, Tsankova NM, Jette N, Hoffman GE<\/strong>, Akbarian S, Fowkes M, Crary JF, Yuan GC, Roussos P.<\/strong> Genome Med. 2021 Jul 19;13(1):118. doi: 10.1186\/s13073-021-00933-8.<\/em> PMID: 34281603<\/p>

Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer's Disease.<\/a><\/strong>
Alldred MJ, Penikalapati SC, Lee SH, Heguy A,\u00a0Roussos P<\/strong>, Ginsberg SD. Mol Neurobiol. 2021 Jul 14. doi: 10.1007\/s12035-021-02453-3. Online ahead of print.<\/em>PMID:<\/em>\u00a0<\/em>34263425<\/em><\/p>

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders.<\/strong><\/a>
Hu B, Won H, Mah W, Park RB, Kassim B, Spiess K, Kozlenkov A, Crowley CA, Pochareddy S; PsychENCODE Consortium<\/strong>, Li Y, Dracheva S, Sestan N, Akbarian S, Geschwind DH. Nat Commun. 2021 Jun 25;12(1):3968. doi: 10.1038\/s41467-021-24243-0.PMID:\u00a034172755<\/em><\/p>

Sex Differences in the Human Brain Transcriptome of Cases With Schizophrenia.<\/strong><\/a>
Hoffman GE<\/strong>, Ma Y,<\/strong> Montgomery KS, Bendl J<\/strong>, Jaiswal MK, Kozlenkov A, Peters MA, Dracheva S, Fullard JF<\/strong>, Chess A, Devlin B, Sieberts SK,\u00a0Roussos P. <\/strong>Biol Psychiatry. 2021 Mar 25:S0006-3223(21)01180-X. doi: 10.1016\/j.biopsych.2021.03.020. Online ahead of print.PMID:\u00a034154796<\/em><\/p>

Common genetic variation influencing human white matter microstructure.<\/a><\/strong>
Zhao B, Li T, Yang Y, Wang X, Luo T, Shan Y, Zhu Z, Xiong D, Hauberg ME, Bendl J, Fullard JF<\/strong>,\u00a0Roussos P<\/strong>, Li Y, Stein JL, Zhu H. Science. 2021 Jun 18;372(6548):eabf3736. doi: 10.1126\/science.abf3736.PMID:\u00a034140357<\/em><\/p>

IL10RB as a key regulator of COVID-19 host susceptibility and severity.<\/strong><\/a>
Voloudakis G, Hoffman G, Venkatesh S<\/strong>, Lee KM, Dobrindt K, Vicari JM, Zhang W<\/strong>, Beckmann ND, Jiang S, Hoagland D, Bian J, Gao L, Corvelo A, Cho K, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative, Brennand KJ, Lynch JA, Fullard JF<\/strong>,\u00a0Roussos P. <\/strong>medRxiv. 2021 Jun 2:2021.05.31.21254851. doi: 10.1101\/2021.05.31.21254851. Preprint.PMID:\u00a034100031<\/em>
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Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.<\/strong><\/a>
Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, J\u00f6nsson EG, Palotie A, Ehrenreich H, Begemann M, Steixner-Kumar A, Sham PC, Iwata N, Weinberger DR, Gejman PV, Sanders AR, Buxbaum JD, Rujescu D, Giegling I, Konte B, Hartmann AM, Bramon E, Murray RM, Pato MT, Lee J, Melle I, Molden E, Ophoff RA, McQuillin A, Bass NJ, Adolfsson R, Malhotra AK; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>, Martin NG, Fullerton JM, Mitchell PB, Schofield PR, Forstner AJ, Degenhardt F, Schaupp S, Comes AL, Kogevinas M, Guzman-Parra J, Reif A, Streit F, Sirignano L, Cichon S, Grigoroiu-Serbanescu M, Hauser J, Lissowska J, Mayoral F, M\u00fcller-Myhsok B, \u015awi\u0105tkowska B, Schulze TG, N\u00f6then MM, Rietschel M, Kelsoe J, Leboyer M, Jamain S, Etain B, Bellivier F, Vincent JB, Alda M, O'Donovan C, Cervantes P, Biernacka JM, Frye M, McElroy SL, Scott LJ, Stahl EA, Land\u00e9n M, Hamshere ML, Smeland OB, Djurovic S, Vaaler AE, Andreassen OA; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>, Baune BT, Air T, Preisig M, Uher R, Levinson DF, Weissman MM, Potash JB, Shi J, Knowles JA, Perlis RH, Lucae S, Boomsma DI, Penninx BWJH, Hottenga JJ, de Geus EJC, Willemsen G, Milaneschi Y, Tiemeier H, Grabe HJ, Teumer A, Van der Auwera S, V\u00f6lker U, Hamilton SP, Magnusson PKE, Viktorin A, Mehta D, Mullins N, Adams MJ, Breen G, McIntosh AM, Lewis CM; Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium<\/strong>; iPSYCH, Hougaard DM, Nordentoft M, Mors O, Mortensen PB, Werge T, Als TD, B\u00f8rglum AD, Petryshen TL, Smoller JW, Goldstein JM. Biol Psychiatry. 2021 Mar 23:S0006-3223(21)01139-2. doi: 10.1016\/j.biopsych.2021.02.972. Online ahead of print.PMID:\u00a034099189<\/em><\/p>

scGRNom: a computational pipeline of integrative multi-omics analyses for predicting cell-type disease genes and regulatory networks.<\/strong><\/a>
Jin T, Rehani P, Ying M, Huang J, Liu S,\u00a0Roussos P<\/strong>, Wang D. Genome Med. 2021 May 27;13(1):95. doi: 10.1186\/s13073-021-00908-9.PMID:\u00a034044854<\/em>
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Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics.<\/strong><\/a>
Lam M, Chen CY, Ge T, Xia Y, Hill DW, Trampush JW, Yu J, Knowles E, Davies G, Stahl EA, Huckins L, Liewald DC, Djurovic S, Melle I, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AM,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Koltai DC, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Smyrnis N, Bilder RM, Freimer NB, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Huang H, Liu C, Malhotra AK, Lencz T. Neuropsychopharmacology. 2021 May 25. doi: 10.1038\/s41386-021-01023-4. Online ahead of print.PMID:\u00a034035472<\/em><\/p>

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.<\/a><\/strong>
Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, B\u00f8rte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HH, Abramova L, Adorjan K, Agerbo E, Al Eissa M, Albani D, Alliey-Rodriguez N, Anjorin A, Antilla V, Antoniou A, Awasthi S, Baek JH, B\u00e6kvad-Hansen M, Bass N, Bauer M, Beins EC, Bergen SE, Birner A, B\u00f8cker Pedersen C, B\u00f8en E, Boks MP, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cairns M, Casas M, Cervantes P, Clarke TK, Cruceanu C, Cuellar-Barboza A, Cunningham J, Curtis D, Czerski PM, Dale AM, Dalkner N, David FS, Degenhardt F, Djurovic S, Dobbyn AL, Douzenis A, Elvs\u00e5shagen T, Escott-Price V, Ferrier IN, Fiorentino A, Foroud TM, Forty L, Frank J, Frei O, Freimer NB, Fris\u00e9n L, Gade K, Garnham J, Gelernter J, Gi\u00f8rtz Pedersen M, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha K, Haraldsson M, Hautzinger M, Heilbronner U, Hellgren D, Herms S, Hoffmann P, Holmans PA, Huckins L, Jamain S, Johnson JS, Kalman JL, Kamatani Y, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koromina M, Kranz TM, Kranzler HR, Kubo M, Kupka R, Kushner SA, Lavebratt C, Lawrence J, Leber M, Lee HJ, Lee PH, Levy SE, Lewis C, Liao C, Lucae S, Lundberg M, MacIntyre DJ, Magnusson SH, Maier W, Maihofer A, Malaspina D, Maratou E, Martinsson L, Mattheisen M, McCarroll SA, McGregor NW, McGuffin P, McKay JD, Medeiros H, Medland SE, Millischer V, Montgomery GW, Moran JL, Morris DW, M\u00fchleisen TW, O'Brien N, O'Donovan C, Olde Loohuis LM, Oruc L, Papiol S, Pardi\u00f1as AF, Perry A, Pfennig A, Porichi E, Potash JB, Quested D, Raj T, Rapaport MH, DePaulo JR, Regeer EJ, Rice JP, Rivas F, Rivera M, Roth J,\u00a0Roussos P<\/strong>, Ruderfer DM, S\u00e1nchez-Mora C, Schulte EC, Senner F, Sharp S, Shilling PD, Sigurdsson E, Sirignano L, Slaney C, Smeland OB, Smith DJ, Sobell JL, S\u00f8holm Hansen C, Soler Artigas M, Spijker AT, Stein DJ, Strauss JS, \u015awi\u0105tkowska B, Terao C, Thorgeirsson TE, Toma C, Tooney P, Tsermpini EE, Vawter MP, Vedder H, Walters JTR, Witt SH, Xi S, Xu W, Yang JMK, Young AH, Young H, Zandi PP, Zhou H, Zillich L; HUNT All-In Psychiatry, Adolfsson R, Agartz I, Alda M, Alfredsson L, Babadjanova G, Backlund L, Baune BT, Bellivier F, Bengesser S, Berrettini WH, Blackwood DHR, Boehnke M, B\u00f8rglum AD, Breen G, Carr VJ, Catts S, Corvin A, Craddock N, Dannlowski U, Dikeos D, Esko T, Etain B, Ferentinos P, Frye M, Fullerton JM, Gawlik M, Gershon ES, Goes FS, Green MJ, Grigoroiu-Serbanescu M, Hauser J, Henskens F, Hillert J, Hong KS, Hougaard DM, Hultman CM, Hveem K, Iwata N, Jablensky AV, Jones I, Jones LA, Kahn RS, Kelsoe JR, Kirov G, Land\u00e9n M, Leboyer M, Lewis CM, Li QS, Lissowska J, Lochner C, Loughland C, Martin NG, Mathews CA, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Michie P, Milani L, Mitchell PB, Morken G, Mors O, Mortensen PB, Mowry B, M\u00fcller-Myhsok B, Myers RM, Neale BM, Nievergelt CM, Nordentoft M, N\u00f6then MM, O'Donovan MC, Oedegaard KJ, Olsson T, Owen MJ, Paciga SA, Pantelis C, Pato C, Pato MT, Patrinos GP, Perlis RH, Posthuma D, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribas\u00e9s M, Rietschel M, Ripke S, Rouleau GA, Saito T, Schall U, Schalling M, Schofield PR, Schulze TG, Scott LJ, Scott RJ, Serretti A, Shannon Weickert C, Smoller JW, Stefansson H, Stefansson K, Stordal E, Streit F, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Waldman ID, Weickert TW, Werge T, Wray NR, Zwart JA, Biernacka JM, Nurnberger JI, Cichon S, Edenberg HJ, Stahl EA, McQuillin A, Di Florio A, Ophoff RA, Andreassen OA. Nat Genet. 2021 Jun;53(6):817-829. doi: 10.1038\/s41588-021-00857-4. Epub 2021 May 17.PMID:\u00a034002096<\/em><\/p>

Sex Differences in Molecular Rhythms in the Human Cortex.<\/strong><\/a>
Logan RW, Xue X, Ketchesin KD, Hoffman G,\u00a0Roussos P<\/strong>, Tseng G, McClung CA, Seney ML. Biol Psychiatry. 2021 Mar 8:S0006-3223(21)01110-0. doi: 10.1016\/j.biopsych.2021.03.005. Online ahead of print.PMID:\u00a033934884<\/em><\/p>

Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.<\/a><\/strong>
Novikova G, Kapoor M, Tcw J, Abud EM, Efthymiou AG, Chen SX, Cheng H, Fullard JF, Bendl J,<\/strong> Liu Y,\u00a0Roussos P<\/strong>, Bj\u00f6rkegren JL, Liu Y, Poon WW, Hao K, Marcora E, Goate AM. Nat Commun. 2021 Mar 12;12(1):1610. doi: 10.1038\/s41467-021-21823-y.PMID:\u00a033712570<\/em>
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Disruption of nuclear architecture as a cause of COVID-19 induced anosmia.<\/strong><\/a>
Zazhytska M, Kodra A, Hoagland DA, Fullard JF<\/strong>, Shayya H, Omer A, Firestein S, Gong Q, Canoll PD, Goldman JE,\u00a0Roussos P<\/strong>, tenOever BR, Overdevest JB, Lomvardas S. bioRxiv. 2021 Feb 9:2021.02.09.430314. doi: 10.1101\/2021.02.09.430314. Preprint.PMID: 33594368<\/em><\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2020\" open=\"off\" closed_toggle_background_color=\"#eaeaea\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2020\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" vertical_offset_tablet=\"0\" horizontal_offset_tablet=\"0\" border_radii=\"on|6px|6px|6px|6px\" border_width_all=\"0.5px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons.<\/strong><\/a>
Hauberg ME<\/strong>, Creus-Muncunill J, Bendl<\/strong> J, Kozlenkov A, Zeng B,<\/strong> Corwin C, Chowdhury S, Kranz H, Hurd YL, Wegner M, B\u00f8rglum AD, Dracheva S, Ehrlich ME, Fullard JF<\/strong>,\u00a0Roussos P. <\/strong>Nat Commun. 2020 Nov 4;11(1):5581. doi: 10.1038\/s41467-020-19319-2.PMID:\u00a033149216<\/em>\u00a0Free PMC article.<\/strong><\/p>

Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network.<\/strong><\/a>
Yazdani A, Mendez-Giraldez R, Yazdani A, Kosorok MR,\u00a0Roussos P. <\/strong>BMC Bioinformatics. 2020 Oct 21;21(1):469. doi: 10.1186\/s12859-020-03753-6.PMID:\u00a033087039<\/em>\u00a0Free PMC article.<\/strong><\/p>

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.<\/strong><\/a>
Sieberts SK, Perumal TM, Carrasquillo MM, Allen M, Reddy JS, Hoffman GE, Dang KK, Calley J, Ebert PJ, Eddy J, Wang X, Greenwood AK, Mostafavi S; CommonMind Consortium (CMC)<\/strong>; The AMP-AD Consortium, Omberg L, Peters MA, Logsdon BA, De Jager PL, Ertekin-Taner N, Mangravite LM. Sci Data. 2020 Oct 12;7(1):340. doi: 10.1038\/s41597-020-00642-8.PMID: 33046718<\/em>\u00a0Free PMC article.<\/strong><\/p>

Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder.<\/strong><\/a>
Egervari G, Akpoyibo D, Rahman T, Fullard JF,<\/strong> Callens JE, Landry JA, Ly A, Zhou X, Warren N, Hauberg ME<\/strong>, Hoffman G<\/strong>, Ellis R, Ferland JN, Miller ML, Keller E, Zhang B,\u00a0Roussos P<\/strong>, Hurd YL. Nat Commun. 2020 Sep 14;11(1):4634. doi: 10.1038\/s41467-020-18114-3.PMID: 32929078<\/em>
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dream: Powerful differential expression analysis for repeated measures designs.<\/strong><\/a>
Hoffman GE<\/strong>, Roussos P. <\/strong>Bioinformatics. 2020 Jul 30:btaa687. doi: 10.1093\/bioinformatics\/btaa687. Online ahead of print.PMID:\u00a032730587<\/em><\/p>

Functional annotation of rare structural variation in the human brain.<\/strong><\/a>
Han L, Zhao X, Benton ML, Perumal T, Collins RL, Hoffman GE<\/strong>, Johnson JS, Sloofman L, Wang HZ, Stone MR; CommonMind Consortium<\/strong>, Brennand KJ, Brand H, Sieberts SK, Marenco S, Peters MA, Lipska BK,\u00a0Roussos P<\/strong>, Capra JA, Talkowski M, Ruderfer DM. Nat Commun. 2020 Jun 12;11(1):2990. doi: 10.1038\/s41467-020-16736-1.PMID: 32533064<\/em>\u00a0Free PMC article.<\/strong><\/p>

Complement genes contribute sex-biased vulnerability in diverse disorders.<\/a><\/strong>
Kamitaki N, Sekar A, Handsaker RE, de Rivera H, Tooley K, Morris DL, Taylor KE, Whelan CW, Tombleson P, Loohuis LMO; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Boehnke M, Kimberly RP, Kaufman KM, Harley JB, Langefeld CD, Seidman CE, Pato MT, Pato CN, Ophoff RA, Graham RR, Criswell LA, Vyse TJ, McCarroll SA. Nature. 2020 Jun;582(7813):577-581. doi: 10.1038\/s41586-020-2277-x. Epub 2020 May 11.PMID: 32499649<\/em><\/p>

Big Data Analysis and Genetic Liability to Neuropsychiatric Disease.<\/strong><\/a>
Roussos P. <\/strong>Adv Exp Med Biol. 2020;1194:455. doi: 10.1007\/978-3-030-32622-7_43.PMID:\u00a032468561<\/em><\/p>

A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons.<\/strong><\/a>
Espeso-Gil S, Halene T, Bendl J, Kassim B, Ben Hutta G, Iskhakova M, Shokrian N, Auluck P, Javidfar B, Rajarajan P, Chandrasekaran S, Peter CJ, Cote A, Birnbaum R, Liao W, Borrman T, Wiseman J, Bell A, Bannon MJ,\u00a0Roussos P<\/strong>, Crary JF, Weng Z, Marenco S, Lipska B, Tsankova NM, Huckins L, Jiang Y, Akbarian S. Genome Med. 2020 Feb 19;12(1):19. doi: 10.1186\/s13073-020-0715-x.PMID: 32075678<\/em>
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Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer's disease.<\/strong><\/a>
Woo YJ,\u00a0Roussos P<\/strong>, Haroutunian V, Katsel P, Gandy S, Schadt EE, Zhu J; Alzheimer Disease Neuroimaging Initiative (ADNI).BMC Med. 2020 Feb 6;18(1):23. doi: 10.1186\/s12916-019-1488-1.PMID:\u00a032024511<\/em>
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decorate: differential epigenetic correlation test.<\/strong><\/a>
Hoffman GE, Bendl J, Girdhar K<\/strong>, Roussos P. <\/strong>Bioinformatics. 2020 May 1;36(9):2856-2861. doi: 10.1093\/bioinformatics\/btaa067.PMID:\u00a032003784<\/em><\/p>

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.<\/strong><\/a>
Coleman JRI, Gaspar HA, Bryois J; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Breen G. Biol Psychiatry. 2020 Jul 15;88(2):169-184. doi: 10.1016\/j.biopsych.2019.10.015. Epub 2019 Nov 1.PMID: 31926635<\/em><\/p>

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.<\/strong><\/a>
Andlauer TFM, Guzman-Parra J, Streit F, Strohmaier J, Gonz\u00e1lez MJ, Gil Flores S, Cabaleiro Fabeiro FJ, Del R\u00edo Noriega F, Perez FP, Haro Gonz\u00e1lez J, Orozco Diaz G, de Diego-Otero Y, Moreno-K\u00fcstner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Treutlein J, Witt SH, Cichon S, Kogevinas M; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Rivas F, Mayoral F, M\u00fcller-Myhsok B, Forstner AJ, N\u00f6then MM, Rietschel M. Mol Psychiatry. 2019 Nov 11. doi: 10.1038\/s41380-019-0558-2. Online ahead of print<\/em>.PMID: 31712721<\/p>

CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.<\/strong><\/a>
Hoffman GE, Bendl J, Voloudakis G<\/strong>, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K<\/strong>, Song L, Fullard JF<\/strong>, Kramer R, Hahn CG, Gur R, Marenco S, Lipska BK, Lewis DA, Haroutunian V, Hemby S, Sullivan P, Akbarian S, Chess A, Buxbaum JD, Crawford GE, Domenici E, Devlin B, Sieberts SK, Peters MA, Roussos P<\/strong>.
Sci Data. 2019 Sep 24;6(1):180. doi: 10.1038\/s41597-019-0183-6.<\/em> PMID: 31551426<\/p>

Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification.<\/strong><\/a>
Hoffman GE, Bendl J, Girdhar K<\/strong>, Schadt EE, Roussos P<\/strong>.
Nucleic Acids Res. 2019 Sep 23. pii: gkz808. doi: 10.1093\/nar\/gkz808. [Epub ahead of print]<\/em> PMID: 31544924<\/p>

A polygenic resilience score moderates the genetic risk for schizophrenia.<\/strong><\/a>
Hess JL, Tylee DS, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>; Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), B\u00f8rglum AD, Als TD, Grove J, Werge T, Mortensen PB, Mors O, Nordentoft M, Hougaard DM, Byberg-Grauholm J, B\u00e6kvad-Hansen M, Greenwood TA, Tsuang MT, Curtis D, Steinberg S, Sigurdsson E, Stef\u00e1nsson H, Stef\u00e1nsson K, Edenberg HJ, Holmans P, Faraone SV, Glatt SJ.
Mol Psychiatry. 2019 Sep 6. doi: 10.1038\/s41380-019-0463-8. [Epub ahead of print]<\/em> PMID: 31492941<\/p>

Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia.<\/strong><\/a>
Breen MS, Dobbyn A, Li Q, Roussos P<\/strong>, Hoffman GE<\/strong>, Stahl E, Chess A, Sklar P, Li JB, Devlin B, Buxbaum JD; CommonMind Consortium.
Nat Neurosci. 2019 Sep;22(9):1402-1412. doi: 10.1038\/s41593-019-0463-7. Epub 2019 Aug 27.<\/em> PMID:31455887<\/p>

Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.<\/strong><\/a>
Zhang W, Voloudakis G, Rajagopal VM,<\/strong> Readhead B, Dudley JT, Schadt EE, Bj\u00f6rkegren JLM, Kim Y, Fullard JF, Hoffman GE<\/strong>, Roussos P<\/strong>.
Nat Commun. 2019 Aug 23;10(1):3834. doi: 10.1038\/s41467-019-11874-7<\/em>. PMID:31444360<\/p>

Genetic Variation in Long-Range Enhancers.<\/a><\/strong>
Fullard JF, Rahman S<\/strong>, Roussos P<\/strong>.
Curr Top Behav Neurosci. 2019 Aug 9. doi: 10.1007\/7854_2019_110. [Epub ahead of print<\/em>] PMID:31396896<\/p>

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.<\/strong><\/a>
Lam M, Hill WD, Trampush JW, Yu J, Knowles E, Davies G, Stahl E, Huckins L, Liewald DC, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AM, Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Am J Hum Genet. 2019 Aug 1;105(2):334-350. doi: 10.1016\/j.ajhg.2019.06.012.<\/em>PMID:31374203<\/p>

Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM<\/strong>, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Jun;51(6):1068. doi: 10.1038\/s41588-019-0435-6.<\/em> PMID:31086353<\/p>

Genome-wide association study identifies 30 loci associated with bipolar disorder.<\/strong><\/a>
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, B\u00e6kvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, B\u00f8en E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvs\u00e5shagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Fris\u00e9n L, Gade K, Gage D, Garnham J, Giambartolomei C<\/strong>, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS<\/strong>, Jur\u00e9us A, Kandaswamy R, Karlsson R, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koller AC, Kupka R, Lavebratt C, Lawrence J, Lawson WB, Leber M, Lee PH, Levy SE, Li JZ, Liu C, Lucae S, Maaser A, MacIntyre DJ, Mahon PB, Maier W, Martinsson L, McCarroll S, McGuffin P, McInnis MG, McKay JD, Medeiros H, Medland SE, Meng F, Milani L, Montgomery GW, Morris DW, M\u00fchleisen TW, Mullins N, Nguyen H, Nievergelt CM, Adolfsson AN, Nwulia EA, O'Donovan C, Loohuis LMO, Ori APS, Oruc L, \u00d6sby U, Perlis RH, Perry A, Pfennig A, Potash JB, Purcell SM, Regeer EJ, Reif A, Reinbold CS, Rice JP, Rivas F, Rivera M, Roussos P<\/strong>, Ruderfer DM, Ryu E, S\u00e1nchez-Mora C, Schatzberg AF, Scheftner WA, Schork NJ, Shannon Weickert C, Shehktman T, Shilling PD, Sigurdsson E, Slaney C, Smeland OB, Sobell JL, S\u00f8holm Hansen C, Spijker AT, St Clair D, Steffens M, Strauss JS, Streit F, Strohmaier J, Szelinger S, Thompson RC, Thorgeirsson TE, Treutlein J, Vedder H, Wang W, Watson SJ, Weickert TW, Witt SH, Xi S, Xu W, Young AH, Zandi P, Zhang P, Z\u00f6llner S; eQTLGen Consortium; BIOS Consortium, Adolfsson R, Agartz I, Alda M, Backlund L, Baune BT, Bellivier F, Berrettini WH, Biernacka JM, Blackwood DHR, Boehnke M, B\u00f8rglum AD, Corvin A, Craddock N, Daly MJ, Dannlowski U, Esko T, Etain B, Frye M, Fullerton JM, Gershon ES, Gill M, Goes F, Grigoroiu-Serbanescu M, Hauser J, Hougaard DM, Hultman CM, Jones I, Jones LA, Kahn RS, Kirov G, Land\u00e9n M, Leboyer M, Lewis CM, Li QS, Lissowska J, Martin NG, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Metspalu A, Mitchell PB, Morken G, Mors O, Mortensen PB, M\u00fcller-Myhsok B, Myers RM, Neale BM, Nimgaonkar V, Nordentoft M, N\u00f6then MM, O'Donovan MC, Oedegaard KJ, Owen MJ, Paciga SA, Pato C, Pato MT, Posthuma D, Ramos-Quiroga JA, Ribas\u00e9s M, Rietschel M, Rouleau GA, Schalling M, Schofield PR, Schulze TG, Serretti A, Smoller JW, Stefansson H, Stefansson K, Stordal E, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Werge T, Nurnberger JI, Wray NR, Di Florio A, Edenberg HJ, Cichon S, Ophoff RA, Scott LJ, Andreassen OA, Kelsoe J, Sklar P; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium.
Nat Genet. 2019 May;51(5):793-803. doi: 10.1038\/s41588-019-0397-8. Epub 2019 May 1<\/em>. PMID:31043756<\/p>

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.<\/a><\/strong>
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, B\u00f6hmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, K\u00e4h\u00f6nen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtim\u00e4ki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytik\u00e4inen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P<\/strong>, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumar\u00e9 A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, H\u00e4gg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, R\u00e4ikk\u00f6nen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.
Nat Commun. 2019 May 1;10(1):2068. doi: 10.1038\/s41467-019-10160-w.<\/em> PMID:31043617<\/p>

Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes.<\/strong><\/a>
Drange OK, Smeland OB, Shadrin AA, Finseth PI, Witoelar A, Frei O; Psychiatric Genomics Consortium Bipolar Disorder Working Group,<\/strong> Wang Y, Hassani S, Djurovic S, Dale AM, Andreassen OA.
Front Neurosci. 2019 Mar 13;13:220. doi: 10.3389\/fnins.2019.00220. eCollection 2019.<\/em> PMID:30930738<\/p>

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM<\/strong>, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Apr;51(4):659-674. doi: 10.1038\/s41588-019-0364-4. Epub 2019 Mar 25. Erratum in: Nat Genet. 2019 Jun;51(6):1068<\/a>.<\/em> \u00a0PMID:30911161<\/p>

Identification of common genetic risk variants for autism spectrum disorder.<\/strong><\/a>
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, N\u00e6rland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnstr\u00f6m K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos P<\/strong>, Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, B\u00f8rglum AD.
Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038\/s41588-019-0344-8. Epub 2019 Feb 25.<\/em> PMID:30804558<\/p>

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.<\/strong><\/a>
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O'Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Donohoe G, Gill M, Corvin A, Morris DW.
Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002\/ajmg.b.32716. Epub 2019 Feb 23.<\/em> PMID:30801977<\/p>

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V.
NPJ Schizophr. 2019 Jan 29;5(1):3. doi: 10.1038\/s41537-019-0071-2.<\/em> PMID:30696826<\/p>

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium<\/strong>; Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Mar 25. doi: 10.1038\/s41588-019-0364-4. [Epub ahead of print]<\/em> PMID:30911161<\/p>

Cell- and layer-specific transcriptomic strategy for characterizing the molecular phenotype of rat cortical neurons using laser capture microdissection and massively parallel RNA sequencing.<\/strong><\/a>
Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P,<\/strong> Shen L, Baxter MG, Hurd YL.
Mol Psychiatry. 2019 Apr;24(4):473. doi: 10.1038\/s41380-019-0390-8. No abstract available.<\/em>PMID:30899095<\/p>

Identification of common genetic risk variants for autism spectrum disorder.<\/strong><\/a>
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, N\u00e6rland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnstr\u00f6m K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos<\/strong> P,<\/strong> Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, B\u00f8rglum AD.
Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038\/s41588-019-0344-8. Epub 2019 Feb 25.<\/em> PMID:30804558<\/p>

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.<\/strong><\/a>
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O'Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Donohoe G, Gill M, Corvin A, Morris DW.
Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002\/ajmg.b.32716. Epub 2019 Feb 23<\/em>. PMID:30801977<\/p>

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V.
NPJ Schizophr. 2019 Jan 29;5(1):3. doi: 10.1038\/s41537-019-0071-2.<\/em> PMID: 30696826<\/p>

Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia.<\/strong><\/a>
Fullard JF<\/strong>, Charney AW, Voloudakis G<\/strong>, Uzilov AV, Haroutunian V, Roussos P<\/strong>.
Transl Psychiatry. 2019 Jan 17;9(1):21. doi: 10.1038\/s41398-018-0342-0.<\/em> PMID: 30655504<\/p>

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Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.<\/strong><\/a>
Andlauer TFM, Guzman-Parra J, Streit F, Strohmaier J, Gonz\u00e1lez MJ, Gil Flores S, Cabaleiro Fabeiro FJ, Del R\u00edo Noriega F, Perez FP, Haro Gonz\u00e1lez J, Orozco Diaz G, de Diego-Otero Y, Moreno-K\u00fcstner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Treutlein J, Witt SH, Cichon S, Kogevinas M; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium<\/strong>; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Rivas F, Mayoral F, M\u00fcller-Myhsok B, Forstner AJ, N\u00f6then MM, Rietschel M.Mol Psychiatry. 2019 Nov 11. doi: 10.1038\/s41380-019-0558-2. Online ahead of print.PMID:\u00a031712721<\/p>

CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.<\/strong><\/a>
Hoffman GE, Bendl J, Voloudakis G<\/strong>, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K<\/strong>, Song L, Fullard JF<\/strong>, Kramer R, Hahn CG, Gur R, Marenco S, Lipska BK, Lewis DA, Haroutunian V, Hemby S, Sullivan P, Akbarian S, Chess A, Buxbaum JD, Crawford GE, Domenici E, Devlin B, Sieberts SK, Peters MA, Roussos P<\/strong>.
Sci Data. 2019 Sep 24;6(1):180. doi: 10.1038\/s41597-019-0183-6.<\/em> PMID: 31551426<\/p>

Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification.<\/strong><\/a>
Hoffman GE, Bendl J, Girdhar K<\/strong>, Schadt EE, Roussos P<\/strong>.
Nucleic Acids Res. 2019 Sep 23. pii: gkz808. doi: 10.1093\/nar\/gkz808. [Epub ahead of print]<\/em> PMID: 31544924<\/p>

A polygenic resilience score moderates the genetic risk for schizophrenia.<\/strong><\/a>
Hess JL, Tylee DS, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>; Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), B\u00f8rglum AD, Als TD, Grove J, Werge T, Mortensen PB, Mors O, Nordentoft M, Hougaard DM, Byberg-Grauholm J, B\u00e6kvad-Hansen M, Greenwood TA, Tsuang MT, Curtis D, Steinberg S, Sigurdsson E, Stef\u00e1nsson H, Stef\u00e1nsson K, Edenberg HJ, Holmans P, Faraone SV, Glatt SJ.
Mol Psychiatry. 2019 Sep 6. doi: 10.1038\/s41380-019-0463-8. [Epub ahead of print]<\/em> PMID: 31492941<\/p>

Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia.<\/strong><\/a>
Breen MS, Dobbyn A, Li Q, Roussos P<\/strong>, Hoffman GE<\/strong>, Stahl E, Chess A, Sklar P, Li JB, Devlin B, Buxbaum JD; CommonMind Consortium.
Nat Neurosci. 2019 Sep;22(9):1402-1412. doi: 10.1038\/s41593-019-0463-7. Epub 2019 Aug 27.<\/em> PMID:31455887<\/p>

Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.<\/strong><\/a>
Zhang W, Voloudakis G, Rajagopal VM,<\/strong> Readhead B, Dudley JT, Schadt EE, Bj\u00f6rkegren JLM, Kim Y, Fullard JF, Hoffman GE<\/strong>, Roussos P<\/strong>.
Nat Commun. 2019 Aug 23;10(1):3834. doi: 10.1038\/s41467-019-11874-7<\/em>. PMID:31444360<\/p>

Genetic Variation in Long-Range Enhancers.<\/a>
Fullard JF, Rahman S<\/strong>, Roussos P<\/strong>.
Curr Top Behav Neurosci. 2019 Aug 9. doi: 10.1007\/7854_2019_110. [Epub ahead of print<\/em>] PMID:31396896<\/p>

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.<\/strong><\/a>
Lam M, Hill WD, Trampush JW, Yu J, Knowles E, Davies G, Stahl E, Huckins L, Liewald DC, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AM, Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Am J Hum Genet. 2019 Aug 1;105(2):334-350. doi: 10.1016\/j.ajhg.2019.06.012.<\/em>PMID:31374203<\/p>

Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM<\/strong>, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Jun;51(6):1068. doi: 10.1038\/s41588-019-0435-6.<\/em> PMID:31086353<\/p>

Genome-wide association study identifies 30 loci associated with bipolar disorder.<\/strong><\/a>
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, B\u00e6kvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, B\u00f8en E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvs\u00e5shagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Fris\u00e9n L, Gade K, Gage D, Garnham J, Giambartolomei C<\/strong>, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS<\/strong>, Jur\u00e9us A, Kandaswamy R, Karlsson R, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koller AC, Kupka R, Lavebratt C, Lawrence J, Lawson WB, Leber M, Lee PH, Levy SE, Li JZ, Liu C, Lucae S, Maaser A, MacIntyre DJ, Mahon PB, Maier W, Martinsson L, McCarroll S, McGuffin P, McInnis MG, McKay JD, Medeiros H, Medland SE, Meng F, Milani L, Montgomery GW, Morris DW, M\u00fchleisen TW, Mullins N, Nguyen H, Nievergelt CM, Adolfsson AN, Nwulia EA, O'Donovan C, Loohuis LMO, Ori APS, Oruc L, \u00d6sby U, Perlis RH, Perry A, Pfennig A, Potash JB, Purcell SM, Regeer EJ, Reif A, Reinbold CS, Rice JP, Rivas F, Rivera M, Roussos P<\/strong>, Ruderfer DM, Ryu E, S\u00e1nchez-Mora C, Schatzberg AF, Scheftner WA, Schork NJ, Shannon Weickert C, Shehktman T, Shilling PD, Sigurdsson E, Slaney C, Smeland OB, Sobell JL, S\u00f8holm Hansen C, Spijker AT, St Clair D, Steffens M, Strauss JS, Streit F, Strohmaier J, Szelinger S, Thompson RC, Thorgeirsson TE, Treutlein J, Vedder H, Wang W, Watson SJ, Weickert TW, Witt SH, Xi S, Xu W, Young AH, Zandi P, Zhang P, Z\u00f6llner S; eQTLGen Consortium; BIOS Consortium, Adolfsson R, Agartz I, Alda M, Backlund L, Baune BT, Bellivier F, Berrettini WH, Biernacka JM, Blackwood DHR, Boehnke M, B\u00f8rglum AD, Corvin A, Craddock N, Daly MJ, Dannlowski U, Esko T, Etain B, Frye M, Fullerton JM, Gershon ES, Gill M, Goes F, Grigoroiu-Serbanescu M, Hauser J, Hougaard DM, Hultman CM, Jones I, Jones LA, Kahn RS, Kirov G, Land\u00e9n M, Leboyer M, Lewis CM, Li QS, Lissowska J, Martin NG, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Metspalu A, Mitchell PB, Morken G, Mors O, Mortensen PB, M\u00fcller-Myhsok B, Myers RM, Neale BM, Nimgaonkar V, Nordentoft M, N\u00f6then MM, O'Donovan MC, Oedegaard KJ, Owen MJ, Paciga SA, Pato C, Pato MT, Posthuma D, Ramos-Quiroga JA, Ribas\u00e9s M, Rietschel M, Rouleau GA, Schalling M, Schofield PR, Schulze TG, Serretti A, Smoller JW, Stefansson H, Stefansson K, Stordal E, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Werge T, Nurnberger JI, Wray NR, Di Florio A, Edenberg HJ, Cichon S, Ophoff RA, Scott LJ, Andreassen OA, Kelsoe J, Sklar P; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium.
Nat Genet. 2019 May;51(5):793-803. doi: 10.1038\/s41588-019-0397-8. Epub 2019 May 1<\/em>. PMID:31043756<\/p>

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.<\/a><\/strong>
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, B\u00f6hmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, K\u00e4h\u00f6nen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtim\u00e4ki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytik\u00e4inen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P<\/strong>, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumar\u00e9 A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, H\u00e4gg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, R\u00e4ikk\u00f6nen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.
Nat Commun. 2019 May 1;10(1):2068. doi: 10.1038\/s41467-019-10160-w.<\/em> PMID:31043617<\/p>

Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes.<\/strong><\/a>
Drange OK, Smeland OB, Shadrin AA, Finseth PI, Witoelar A, Frei O; Psychiatric Genomics Consortium Bipolar Disorder Working Group,<\/strong> Wang Y, Hassani S, Djurovic S, Dale AM, Andreassen OA.
Front Neurosci. 2019 Mar 13;13:220. doi: 10.3389\/fnins.2019.00220. eCollection 2019.<\/em> PMID:30930738<\/p>

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM<\/strong>, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Apr;51(4):659-674. doi: 10.1038\/s41588-019-0364-4. Epub 2019 Mar 25. Erratum in: Nat Genet. 2019 Jun;51(6):1068<\/a>.<\/em> \u00a0PMID:30911161<\/p>

Identification of common genetic risk variants for autism spectrum disorder.<\/strong><\/a>
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, N\u00e6rland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnstr\u00f6m K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos P<\/strong>, Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, B\u00f8rglum AD.
Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038\/s41588-019-0344-8. Epub 2019 Feb 25.<\/em> PMID:30804558<\/p>

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.<\/strong><\/a>
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O'Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Donohoe G, Gill M, Corvin A, Morris DW.
Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002\/ajmg.b.32716. Epub 2019 Feb 23.<\/em> PMID:30801977<\/p>

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V.
NPJ Schizophr. 2019 Jan 29;5(1):3. doi: 10.1038\/s41537-019-0071-2.<\/em> PMID:30696826<\/p>

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.<\/strong><\/a>
Huckins LM, Dobbyn A, Ruderfer DM, Hoffman G<\/strong>, Wang W, Pardi\u00f1as AF, Rajagopal VM, Als TD, T Nguyen H, Girdhar K<\/strong>, Boocock J, Roussos P<\/strong>, Fromer M, Kramer R, Domenici E, Gamazon ER, Purcell S; CommonMind Consortium<\/strong>; Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium; iPSYCH-GEMS Schizophrenia Working Group, Demontis D, B\u00f8rglum AD, Walters JTR, O'Donovan MC, Sullivan P, Owen MJ, Devlin B, Sieberts SK, Cox NJ, Im HK, Sklar P, Stahl EA.
Nat Genet. 2019 Mar 25. doi: 10.1038\/s41588-019-0364-4. [Epub ahead of print]<\/em> PMID:30911161<\/p>

Cell- and layer-specific transcriptomic strategy for characterizing the molecular phenotype of rat cortical neurons using laser capture microdissection and massively parallel RNA sequencing.<\/strong><\/a>
Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P,<\/strong> Shen L, Baxter MG, Hurd YL.
Mol Psychiatry. 2019 Apr;24(4):473. doi: 10.1038\/s41380-019-0390-8. No abstract available.<\/em>PMID:30899095<\/p>

Identification of common genetic risk variants for autism spectrum disorder.<\/strong><\/a>
Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, N\u00e6rland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnstr\u00f6m K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos<\/strong> P,<\/strong> Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, B\u00f8rglum AD.
Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038\/s41588-019-0344-8. Epub 2019 Feb 25.<\/em> PMID:30804558<\/p>

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.<\/strong><\/a>
Harold D, Connolly S, Riley BP, Kendler KS, McCarthy SE, McCombie WR, Richards A, Owen MJ, O'Donovan MC, Walters J; Wellcome Trust Case Control Consortium 2; Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Donohoe G, Gill M, Corvin A, Morris DW.
Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):223-231. doi: 10.1002\/ajmg.b.32716. Epub 2019 Feb 23<\/em>. PMID:30801977<\/p>

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V.
NPJ Schizophr. 2019 Jan 29;5(1):3. doi: 10.1038\/s41537-019-0071-2.<\/em> PMID: 30696826<\/p>

Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia.<\/strong><\/a>
Fullard JF<\/strong>, Charney AW, Voloudakis G<\/strong>, Uzilov AV, Haroutunian V, Roussos P<\/strong>.
Transl Psychiatry. 2019 Jan 17;9(1):21. doi: 10.1038\/s41398-018-0342-0.<\/em> PMID: 30655504<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2018\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2018\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Biopsy During Minimally Invasive Intracerebral Hemorrhage Clot Evacuation.<\/strong><\/a>
Lieber AC, McNeill IT, Scaggiante J, Nistal DA, Fowkes M, Umphlett M, Pan J, Roussos P<\/strong>, Mobbs CV, Mocco J, Kellner CP.
World Neurosurg. 2018 Dec 24. pii: S1878-8750(18)32881-X. doi: 10.1016\/j.wneu.2018.12.058. [Epub ahead of print]<\/em> PMID: 30590212<\/p>

Comprehensive functional genomic resource and integrative model for the human brain.<\/strong><\/a>
Wang D, Liu S, Warrell J, Won H, Shi X, Navarro FCP, Clarke D, Gu M, Emani P, Yang YT, Xu M, Gandal MJ, Lou S, Zhang J, Park JJ, Yan C, Rhie SK, Manakongtreecheep K, Zhou H, Nathan A, Peters M, Mattei E, Fitzgerald D, Brunetti T, Moore J, Jiang Y, Girdhar K<\/strong>, Hoffman GE<\/strong>, Kalayci S, G\u00fcm\u00fc\u015f ZH, Crawford GE; PsychENCODE Consortium, Roussos P<\/strong>, Akbarian S, Jaffe AE, White KP, Weng Z, Sestan N, Geschwind DH, Knowles JA, Gerstein MB.
Science. 2018 Dec 14;362(6420). pii: eaat8464. doi: 10.1126\/science.aat8464.<\/em> PMID: 30545857<\/p>

Integrative functional genomic analysis of human brain development and neuropsychiatric risks.<\/strong><\/a>
Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, Choi J, Muchnik S, Xu X, Wang D, Lorente-Galdos B, Liu S, Giusti-Rodr\u00edguez P, Won H, de Leeuw CA, Pardi\u00f1as AF; BrainSpan Consortium; PsychENCODE Consortium<\/strong>; PsychENCODE Developmental Subgroup, Hu M, Jin F, Li Y, Owen MJ, O'Donovan MC, Walters JTR, Posthuma D, Levitt P, Weinberger DR, Hyde TM, Kleinman JE, Geschwind DH, Hawrylycz MJ, State MW, Sanders SJ, Sullivan PF, Gerstein MB, Lein ES, Knowles JA, Sestan N.
Science. 2018 Dec 14;362(6420). pii: eaat7615. doi: 10.1126\/science.aat7615.<\/em> PMID: 30545854<\/p>

Transcriptome and epigenome landscape of human cortical development modeled in organoids.<\/strong><\/a>
Amiri A, Coppola G, Scuderi S, Wu F, Roychowdhury T, Liu F, Pochareddy S, Shin Y, Safi A, Song L, Zhu Y, Sousa AMM; PsychENCODE Consortium<\/strong>, Gerstein M, Crawford GE, Sestan N, Abyzov A, Vaccarino FM.
Science. 2018 Dec 14;362(6420). pii: eaat6720. doi: 10.1126\/science.aat6720<\/em>. PMID: 30545853<\/p>

Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk.<\/strong><\/a>
Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casi\u00f1o C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, Ho SM, MacDonald M, Hoffman GE<\/strong>, Roussos P<\/strong>, Zhang B, Hahn CG, Weng Z, Brennand KJ, Akbarian S.
Science. 2018 Dec 14;362(6420). pii: eaat4311. doi: 10.1126\/science.aat4311.<\/em> PMID: 30545851<\/p>

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.<\/strong><\/a>
Franceschini N, Giambartolomei C<\/strong>, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, Nolte IM, Lu L, Scholz M, Sargurupremraj M, Pitk\u00e4nen N, Franz\u00e9n O, Joshi PK, Noordam R, Marioni RE, Hwang SJ, Musani SK, Schminke U, Palmas W, Isaacs A, Correa A, Zonderman AB, Hofman A, Teumer A, Cox AJ, Uitterlinden AG, Wong A, Smit AJ, Newman AB, Britton A, Ruusalepp A, Sennblad B, Hedblad B, Pasaniuc B, Penninx BW, Langefeld CD, Wassel CL, Tzourio C, Fava C, Baldassarre D, O'Leary DH, Teupser D, Kuh D, Tremoli E, Mannarino E, Grossi E, Boerwinkle E, Schadt EE, Ingelsson E, Veglia F, Rivadeneira F, Beutner F, Chauhan G, Heiss G, Snieder H, Campbell H, V\u00f6lzke H, Markus HS, Deary IJ, Jukema JW, de Graaf J, Price J, Pott J, Hopewell JC, Liang J, Thiery J, Engmann J, Gertow K, Rice K, Taylor KD, Dhana K, Kiemeney LALM, Lind L, Raffield LM, Launer LJ, Holdt LM, D\u00f6rr M, Dichgans M, Traylor M, Sitzer M, Kumari M, Kivimaki M, Nalls MA, Melander O, Raitakari O, Franco OH, Rueda-Ochoa OL, Roussos P<\/strong>, Whincup PH, Amouyel P, Giral P, Anugu P, Wong Q, Malik R, Rauramaa R, Burkhardt R, Hardy R, Schmidt R, de Mutsert R, Morris RW, Strawbridge RJ, Wannamethee SG, H\u00e4gg S, Shah S, McLachlan S, Trompet S, Seshadri S, Kurl S, Heckbert SR, Ring S, Harris TB, Lehtim\u00e4ki T, Galesloot TE, Shah T, de Faire U, Plagnol V, Rosamond WD, Post W, Zhu X, Zhang X, Guo X, Saba Y; MEGASTROKE Consortium, Dehghan A, Seldenrijk A, Morrison AC, Hamsten A, Psaty BM, van Duijn CM, Lawlor DA, Mook-Kanamori DO, Bowden DW, Schmidt H, Wilson JF, Wilson JG, Rotter JI, Wardlaw JM, Deanfield J, Halcox J, Lyytik\u00e4inen LP, Loeffler M, Evans MK, Debette S, Humphries SE, V\u00f6lker U, Gudnason V, Hingorani AD, Bj\u00f6rkegren JLM, Casas JP, O'Donnell CJ.
Nat Commun. 2018 Dec 3;9(1):5141. doi: 10.1038\/s41467-018-07340-5.<\/em> PMID: 30510157<\/p>

Discovery of the first genome-wide significant risk loci for attention deficit\/hyperactivity disorder.<\/strong><\/a>
Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, B\u00e6kvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, Gandal M, Goldstein JI, Grasby KL, Grove J, Gudmundsson OO, Hansen CS, Hauberg ME<\/strong>, Hollegaard MV, Howrigan DP, Huang H, Maller JB, Martin AR, Martin NG, Moran J, Pallesen J, Palmer DS, Pedersen CB, Pedersen MG, Poterba T, Poulsen JB, Ripke S, Robinson EB, Satterstrom FK, Stefansson H, Stevens C, Turley P, Walters GB, Won H, Wright MJ; ADHD Working Group of the Psychiatric Genomics Consortium (PGC); Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium; 23andMe Research Team, Andreassen OA, Asherson P, Burton CL, Boomsma DI, Cormand B, Dalsgaard S, Franke B, Gelernter J, Geschwind D, Hakonarson H, Haavik J, Kranzler HR, Kuntsi J, Langley K, Lesch KP, Middeldorp C, Reif A, Rohde LA, Roussos P<\/strong>, Schachar R, Sklar P, Sonuga-Barke EJS, Sullivan PF, Thapar A, Tung JY, Waldman ID, Medland SE, Stefansson K, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Daly MJ, Faraone SV, B\u00f8rglum AD, Neale BM.
Nat Genet. 2019 Jan;51(1):63-75. doi: 10.1038\/s41588-018-0269-7. Epub 2018 Nov 26.<\/em> PMID: 30478444<\/p>

Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer's disease and normalized by treatment with anti-diabetic agents.<\/strong><\/a>
Katsel P, Roussos P<\/strong>, Beeri MS, Gama-Sosa MA, Gandy S, Khan S, Haroutunian V.
PLoS One. 2018 Nov 1;13(11):e0206547. doi: 10.1371\/journal.pone.0206547. eCollection 2018. <\/em>PMID:30383799<\/p>

Adolescent exposure to \u03949<\/sup>-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons.<\/strong><\/a>
Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P<\/strong>, Shen L, Baxter MG, Hurd YL.
Mol Psychiatry. 2018 Oct 3. doi: 10.1038\/s41380-018-0243-x<\/em>. [Epub ahead of print] PMID:30283037<\/p>

mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia.<\/strong><\/a>
Wang HY, MacDonald ML, Borgmann-Winter KE, Banerjee A, Sleiman P, Tom A, Khan A, Lee KC, Roussos P<\/strong>, Siegel SJ, Hemby SE, Bilker WB, Gur RE, Hahn CG.
Mol Psychiatry. 2018 Sep 13. doi: 10.1038\/s41380-018-0234-y<\/em>. [Epub ahead of print] PMID: 30214040<\/p>

T<\/a><\/strong>he Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer\u2019s disease<\/a><\/strong>
Wang M, Beckmann ND, Roussos P<\/strong>, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF<\/strong>, Hauberg ME<\/strong>, Bendl J<\/strong>, Peters MA, Logsdon B, Wang P, Mahajan M, Mangravite LM, Dammer EB, Duong DM, Lah JJ, Seyfried NT, Levey AI, Buxbaum JD, Ehrlich M, Gandy S, Katsel P, Haroutunian V, Schadt E, Zhang B.
Sci Data. 2018 Sep 11;5:180185. <\/em>doi: 10.1038\/sdata.2018.185.<\/em> PMID: 30204156<\/p>

Evaluation of chromatin accessibility in prefrontal<\/a><\/strong> cortex of individuals with schizophrenia<\/strong>
<\/a>Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A,\u00a0Fullard JF<\/strong>,\u00a0Roussos P<\/strong>, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, White KP, Liu C, Reddy TE, Ashley-Koch A, Sullivan PF, Crawford GE.
Nat Commun. 2018 Aug 7;9(1):3121. doi: 10.1038\/s41467-018-05379-y.<\/em>\u00a0PMID: 30087329<\/p>

Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome<\/a><\/strong><\/p>

\"Volume<\/div>

Girdhar K, Hoffman GE<\/strong>, Jiang Y, Brown L, Kundakovic M,\u00a0Hauberg ME, Francoeur NJ<\/strong>, Wang YC, Shah H, Kavanagh DH, Zharovsky E, Jacobov R, Wiseman JR, Park R, Johnson JS<\/strong>, Kassim BS, Sloofman L, Mattei E, Weng Z, Sieberts SK, Peters MA, Harris BT, Lipska BK, Sklar P,\u00a0Roussos P<\/strong>, Akbarian S.
Nat Neurosci. 2018 Jul 23. doi: 10.1038\/s41593-018-0187-0. [Epub ahead of print]\u00a0<\/em>PMID:30038276
\u2190 Featured at journal cover<\/strong> (art created by Jessica Johnson<\/a><\/strong>)<\/p><\/div>

Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)<\/a><\/strong>
Lam M, Trampush JW, Yu J, Knowles E, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Hellard SL, Keller MC, Andreassen OA, Glahn DC, Malhotra AK, Lencz T.
Twin Res Hum Genet. 2018 Jul 13:1-4. doi: 10.1017\/thg.2018.46. [Epub ahead of print]<\/em>\u00a0PMID:30001766<\/p>

Age at first birth in women is genetically associated with increased risk of schizophrenia<\/a><\/strong>
Ni G, Gratten J, Wray NR, Lee SH;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>.
Sci Rep. 2018 Jul 5;8(1):10168. doi: 10.1038\/s41598-018-28160-z.\u00a0<\/em>PMID: 29977057<\/p>

An atlas of chromatin accessibility in the adult human brain<\/a><\/strong>
Fullard JF, Hauberg ME, Bendl J<\/strong>, Egervari G, Cirnaru MD,\u00a0Reach SM<\/strong>, Motl J, Ehrlich ME, Hurd YL,\u00a0Roussos P<\/strong>.
Genome Res. 2018 Jun 26. pii: gr.232488.117. doi: 10.1101\/gr.232488.117. [Epub ahead of print]\u00a0<\/em>PMID: 29945882<\/p>

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence<\/a><\/strong>
Savage JE, Jansen PR, Stringer S, Watanabe K,\u00a0\u2026,\u00a0Roussos P<\/strong>,\u00a0\u2026, Sullivan PF, Vrieze SI, Wright MJ, Posthuma D.
Nat Genet. 2018 Jun 25. doi: 10.1038\/s41588-018-0152-6. [Epub ahead of print]\u00a0<\/em>PMID:29942086<\/p>

Analysis of shared heritability in common disorders of the brain<\/a><\/strong>
Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L,\u00a0\u2026,\u00a0Roussos P<\/strong>,\u00a0\u2026,Sullivan P, Rosand J, Corvin A, Neale BM.
Science. 2018 Jun 22;360(6395). pii: eaap8757. doi: 10.1126\/science.aap8757.\u00a0<\/em>PMID: 29930110<\/p>

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes<\/a><\/strong>
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>. Electronic address: douglas.ruderfer@vanderbilt.edu; Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium.
Cell. 2018 Jun 14;173(7):1705-1715.e16. doi: 10.1016\/j.cell.2018.05.046.\u00a0<\/em>PMID: 29906448<\/p>

Brain Cell Type Specific Gene Expression and Co-expression Network Architectures<\/a><\/strong>
McKenzie AT, Wang M,\u00a0Hauberg ME, Fullard JF<\/strong>, Kozlenkov A, Keenan A, Hurd YL, Dracheva S, Casaccia P,\u00a0Roussos P<\/strong>, Zhang B.
Sci Rep. 2018 Jun 11;8(1):8868. doi: 10.1038\/s41598-018-27293-5.\u00a0<\/em>PMID: 29892006<\/p>

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function<\/a><\/strong>
Davies G, Lam M, Harris SE, Trampush JW,\u2026,\u00a0Roussos P<\/strong>,\u2026, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.
Nat Commun. 2018 May 29;9(1):2098. doi: 10.1038\/s41467-018-04362-x.\u00a0<\/em>PMID: 29844566<\/p>

Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS<\/a><\/strong>
Dobbyn A, Huckins LM, Boocock J, Sloofman LG, Glicksberg BS,\u00a0Giambartolomei C<\/strong>,\u00a0Hoffman GE,<\/strong>\u00a0Perumal TM,\u00a0Girdhar K<\/strong>, Jiang Y, Raj T, Ruderfer DM, Kramer RS, Pinto D; CommonMind Consortium, Akbarian S,\u00a0Roussos P<\/strong>, Domenici E, Devlin B, Sklar P, Stahl EA, Sieberts SK.
Am J Hum Genet. 2018 Jun 7;102(6):1169-1184. doi: 10.1016\/j.ajhg.2018.04.011. Epub 2018 May 24.\u00a0<\/em>PMID: 29805045<\/p>

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood<\/a><\/strong>
Ni G, Moser G;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Wray NR, Lee SH.
Am J Hum Genet. 2018 Apr 26. pii: S0002-9297(18)30110-1. doi: 10.1016\/j.ajhg.2018.03.021. [Epub ahead of print]<\/em>\u00a0PMID: 29754766<\/p>

Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls<\/a><\/strong>
Hauberg ME, Fullard JF,<\/strong>\u00a0Zhu L, Cohain AT,\u00a0Giambartolomei C, Misir R, Reach S,<\/strong>\u00a0Johnson JS<\/strong>, Wang M, Mattheisen M, B\u00f8rglum AD, Zhang B, Sieberts SK, Peters MA, Domenici E, Schadt EE, Devlin B, Sklar P, Roeder K,\u00a0Roussos P<\/strong>; CommonMind Consortium.
Mol Psychiatry. 2018 May 8. doi: 10.1038\/s41380-018-0059-8. [Epub ahead of print]<\/em>\u00a0PMID: 2974012<\/p>

THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders<\/a><\/strong>
Guennewig B, Bitar M, Obiorah I,\u00a0Hanks J,<\/strong>\u00a0O\u2019Brien EA, Kaczorowski DC, Hurd YL,\u00a0Roussos P<\/strong>, Brennand KJ, Barry G.
Transl Psychiatry. 2018 Apr 25;8(1):89. doi: 10.1038\/s41398-018-0137-3<\/em>. PMID:2969137<\/p>

A Bayesian Framework for Multiple Trait Colo-calization from Summary Association Statistics<\/a><\/strong>
Giambartolomei C,<\/strong>\u00a0Zhenli Liu J,\u00a0Zhang W, Hauberg M,<\/strong>\u00a0Shi H, Boocock J, Pickrell J, Jaffe AE; CommonMind Consortium, Pasaniuc B,\u00a0Roussos P<\/strong>.
Bioinformatics. 2018 Mar 19. doi: 10.1093\/bioinformatics\/bty147. [Epub ahead of print]<\/em>\u00a0PMID:29579179<\/p>

Frontal and temporal cortical volume, white matter tract integrity, and hemispheric asymmetry in schizotypal personality disorder<\/strong>
<\/a>Chan CC, Szeszko PR, Wong E, Tang CY, Kelliher C, Penner JD, Perez-Rodriguez MM, Rosell DR, McClure M,\u00a0Roussos P<\/strong>, New AS, Siever LJ, Hazlett EA.
Schizophr Res. 2018 Feb 14<\/em>. pii: S0920-9964(18)30047-1. doi: 10.1016\/j.schres.2018.01.025. [Epub ahead of print] PMID:29454512<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2017\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2017\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Meta-analysis on the association between genetic polymorphisms and prepulse inhibition of the acoustic startle response<\/a><\/strong>
Quednow BB,\u00a0Ejebe K<\/strong>, Wagner M, Giakoumaki SG, Bitsios P, Kumari V,\u00a0Roussos P<\/strong>.
Schizophr Res. 2017 Dec 26. pii: S0920-9964(17)30763-6. doi: 10.1016\/j.schres.2017.12.011. [Epub ahead of print]<\/em>\u00a0PMID: 29287625<\/p>

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets<\/a><\/strong>
Lam M, Trampush JW, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Cell Rep<\/em>. 2017 Nov 28;21(9):2597-2613. doi: 10.1016\/j.celrep.2017.11.028<\/em>. PMID: 29186694<\/p>

Winter birth, urbanicity and immigrant status predict psychometric schizotypy dimensions in adolescents<\/a><\/strong>
Mimarakis D, Roumeliotaki T,\u00a0Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Eur Psychiatry<\/em>. 2017 Sep 18;47:9-18. doi: 10.1016\/j.eurpsy.2017.07.014. [Epub ahead of print]\u00a0<\/em>PMID: 29096131<\/p>

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium<\/a><\/strong>
Trampush JW, Yang MLZ, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Mol Psychiatry<\/em>. 2017 Nov;22(11):1651-1652. doi: 10.1038\/mp.2017. 197.\u00a0 Epub 2017 Sep 12.\u00a0<\/em>PMID: 29068436<\/p>

Stress-Dependent Association Between Polygenic Risk for Schizophrenia and Schizotypal Traits in Young Army Recruits<\/a><\/strong>
Hatzimanolis A, Avramopoulos D, Arking DE, Moes A, Bhatnagar P, Lencz T, Malhotra AK, Giakoumaki SG,\u00a0Roussos P<\/strong>, Smyrnis N, Bitsios P, Stefanis NC.
Schizophr Bull. 2017 Jun 13. doi: 10.1093\/schbul\/sbx074. [Epub ahead of print]\u00a0<\/em>PMID: 29036523<\/p>

A functional genomics predictive network model identifies regulators of inflammatory bowel disease<\/a><\/strong>
Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K,\u00a0Roussos P<\/strong>, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE.
Nat Genet. 2017 Oct;49(10):1437-1449. doi: 10.1038\/ng.3947. Epub 2017 Sep 11<\/em>. PMID: 28892060<\/p>

Dimensional Traits of Schizotypy Associated With Glycine Receptor GLRA1 Polymorphism: An Exploratory Candidate-Gene Association Study<\/a><\/strong>
Vora AK<\/strong>, Fisher AM, New AS, Hazlett EA, McNamara M, Yuan Q, Zhou Z, Hodgkinson C, Goldman D, Siever LJ,\u00a0Roussos P<\/strong>, Perez-Rodriguez MM.
J Pers Disord. 2017 Jul 31:1-12. doi: 10.1521\/pedi_2017_31_303. [Epub ahead of print]\u00a0<\/em>PMID: 28758885<\/p>

The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain<\/a><\/strong>
Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, Peter CJ, C W JT, Safaie BM, Morishita H,\u00a0Roussos P<\/strong>, Nestler EJ, Schaefer A, Tycko B, Brennand KJ, Yagi T, Shen L, Akbarian S.
Nat Genet. 2017 Aug;49(8):1239-1250. doi: 10.1038\/ng.3906. Epub 2017 Jul 3<\/em>. PMID: 28671686<\/p>

Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression<\/a><\/strong>
Hauberg ME<\/strong>,\u00a0Zhang W<\/strong>,\u00a0Giambartolomei C<\/strong>, Franz\u00e9n O, Morris DL, Vyse TJ, Ruusalepp A; CommonMind Consortium, Sklar P, Schadt EE, Bj\u00f6rkegren JLM,\u00a0Roussos P<\/strong>.
Am J Hum Genet. 2017 Jun 1;100(6):885-894. doi: 10.1016\/j.ajhg. 2017.04.016. Epub 2017 May 25.\u00a0<\/em>PMID:28552197<\/p>

minepath.org: a free interactive pathway analysis web server<\/strong><\/a>
Koumakis L,\u00a0Roussos P<\/strong>, Potamias G.
Nucleic Acids Res. 2017 Apr 20. doi: 10.1093\/nar\/gkx278. [Epub ahead of print]<\/em>\u00a0PMID: 28431175<\/p>

Microvascular anomaly conditions in psychiatric disease. Schizophrenia \u2013 angiogenesis connection<\/a><\/strong>
Katsel P,\u00a0Roussos P<\/strong>, Pletnikov M, Haroutunian V.
Neurosci Biobehav Rev. 2017 Jun;77:327-339. doi: 10.1016\/j.neubiorev.2017.04.003. Epub 2017 Apr 8. Review.<\/em>\u00a0PMID: 28396239<\/p>

Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci<\/a><\/strong>
Fullard JF, Giambartolomei C, Hauberg ME,<\/strong>\u00a0Xu K,\u00a0Voloudakis G<\/strong>, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V,\u00a0Roussos P<\/strong>.
Hum Mol Genet. 2018 Jun 29. doi: 10.1093\/hmg\/ddy229. [Epub ahead of print] No abstract available<\/em>. PMID: 29982455<\/p>

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia<\/a><\/strong>
McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O\u2019Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>.
Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038\/ncomms14774.<\/em>\u00a0PMID: 28322246<\/p>

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium<\/a><\/strong>
Trampush JW, Yang ML, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T.
Mol Psychiatry. 2017 Mar;22(3):336-345. doi: 10.1038\/mp. 2016.244. Epub 2017 Jan 17.<\/em>\u00a0PMID: 28093568<\/p>

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder<\/a><\/strong>
Charney AW, Ruderfer DM, Stahl EA, Moran JL, Chambert K, Belliveau RA, Forty L, Gordon-Smith K, Di Florio A, Lee PH, Bromet EJ, Buckley PF, Escamilla MA, Fanous AH, Fochtmann LJ, Lehrer DS, Malaspina D, Marder SR, Morley CP, Nicolini H, Perkins DO, Rakofsky JJ, Rapaport MH, Medeiros H, Sobell JL, Green EK, Backlund L, Bergen SE, Jur\u00e9us A, Schalling M, Lichtenstein P,\u00a0Roussos P<\/strong>, Knowles JA, Jones I, Jones LA, Hultman CM, Perlis RH, Purcell SM, McCarroll SA, Pato CN, Pato MT, Craddock N, Land\u00e9n M, Smoller JW, Sklar P.
Transl Psychiatry. 2017 Jan 10;7(1):e993. doi: 10.1038\/tp.2016.242.<\/em>\u00a0PMID: 28072414<\/p>

Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity<\/a><\/strong>
Carcamo-Orive I,\u00a0Hoffman GE,<\/strong>\u00a0Cundiff P, Beckmann ND, D\u2019Souza SL, Knowles JW, Patel A, Papatsenko D, Abbasi F, Reaven GM, Whalen S, Lee P, Shahbazi M, Henrion MY, Zhu K, Wang S,\u00a0Roussos P<\/strong>, Schadt EE, Pandey G, Chang R, Quertermous T, Lemischka I.
Cell Stem Cell. 2017 Apr 6;20(4):518-532.e9. doi: 10.1016\/j.stem. 2016.11.005. Epub 2016 Dec 22.<\/em>\u00a0PMID: 2801779<\/p>

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects<\/a><\/strong>
Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, \u2026,\u00a0Roussos P<\/strong>, \u2026, Scherer SW, Neale BM, Sebat J; CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium.
Nat Genet. 2017 Jan;49(1):27-35. doi: 10.1038\/ng.3725. Epub 2016 Nov 21.<\/em>\u00a0PMID: 27869829<\/p>

Striatal H3K27 Acetylation Linked to Glutamatergic Gene Dysregulation in Human Heroin Abusers Holds Promise as Therapeutic Target<\/a><\/strong>
Egervari G, Landry J, Callens J,\u00a0Fullard JF<\/strong>,\u00a0Roussos P<\/strong>, Keller E, Hurd YL.
Biol Psychiatry. 2017 Apr 1;81(7):585-594. doi: 10.1016\/j.biopsych. 2016.09.015. Epub 2016 Sep 28.\u00a0<\/em>PMID:27863698<\/p>

\u00a0<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2016\" icon_color=\"#00aeef\" admin_label=\"2016\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Activity-Dependent Changes in Gene Expression in Schizophrenia Human-Induced Pluripotent Stem Cell Neurons
<\/a><\/strong>Roussos P<\/strong>, Guennewig B, Kaczorowski DC, Barry G, Brennand KJ.
<\/span>JAMA Psychiatry. 2016 Nov 1;73(11):1180-1188. doi: 10.1001\/jamapsychiatry.2016.2575.<\/em>\u00a0PMID: 27732689<\/p>

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer\u2019s disease<\/a><\/strong>
Wang M,\u00a0Roussos P<\/strong>, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, Haroutunian V, Zhang B.
Genome Med. 2016 Nov 1;8(1):104.<\/em>\u00a0PMID: 27799057<\/p>

Gene expression elucidates functional impact of polygenic risk for schizophrenia<\/a><\/strong>
Fromer M,\u00a0Roussos P<\/strong>, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, G\u00fcm\u00fc\u015f ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T,\u00a0Fullard JF<\/strong>, Wang YC, Mahajan MC, Derry JM, Dudley JT, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn CG, Lewis DA, Haroutunian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hirai K, Roeder K, Brennand KJ, Katsanis N, Domenici E, Devlin B, Sklar P.
Nat Neurosci. 2016 Nov;19(11):1442-1453. doi: 10.1038\/nn.4399. Epub 2016 Sep 26.<\/em>\u00a0PMID: 27668389<\/p>

Associations of differential schizotypal dimensions with executive working memory: A moderated-mediation analysis<\/strong><\/a>
Zouraraki C, Tsaousis I, Karamaouna P, Karagiannopoulou L,\u00a0Roussos P<\/strong>, Bitsios P, Giakoumaki SG.
Compr Psychiatry. 2016 Nov;71:39-48. doi: 10.1016\/j.comppsych. 2016.08.010. Epub 2016 Aug 21.\u00a0<\/em>PMID: 27621208<\/p>

Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases<\/strong><\/a>
Franz\u00e9n O, Ermel R, Cohain A, Akers NK, Di Narzo A, Talukdar HA, Foroughi-Asl H,\u00a0Giambartolomei C<\/strong>,\u00a0Fullard JF<\/strong>, Sukhavasi K, K\u00f6ks S, Gan LM, Giannarelli C, Kovacic JC, Betsholtz C, Losic B, Michoel T, Hao K,\u00a0Roussos P<\/strong>, Skogsberg J, Ruusalepp A, Schadt EE, Bj\u00f6rkegren JL.
Science. 2016 Aug 19;353(6301):827-30. doi: 10.1126\/science.aad 6970.\u00a0<\/em>PMID: 27540175<\/p>

Cognitive profiles of schizotypal dimensions in a community cohort: Common properties of differential manifestations<\/a><\/strong>
Karagiannopoulou L, Karamaouna P, Zouraraki C,\u00a0Roussos P<\/strong>, Bitsios P, Giakoumaki SG.
J Clin Exp Neuropsychol. 2016 Nov;38(9):1050-63. doi: 10.1080\/13803395.2016.1188890. Epub 2016 Jun 13.\u00a0<\/em>PMID: 27295077<\/p>

Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue<\/a><\/strong>
Kundakovic M, Jiang Y, Kavanagh DH, Dincer A, Brown L, Pothula V, Zharovsky E, Park R, Jacobov R, Magro I, Kassim B, Wiseman J, Dang K, Sieberts SK,\u00a0Roussos P<\/strong>, Fromer M, Harris B, Lipska BK, Peters MA, Sklar P, Akbarian S.
Biol Psychiatry. 2017 Jan 15;81(2):162-170. doi: 10.1016\/j.biopsych. 2016.03.1048. Epub 2016 Mar 9.\u00a0<\/em>PMID: 27113501<\/p>

Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants<\/a><\/strong>
Hauberg ME<\/strong>,\u00a0Roussos P<\/strong>, Grove J, B\u00f8rglum AD, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium.
JAMA Psychiatry. 2016 Apr;73(4):369-77. doi: 10.1001\/jamapsychiatry.2015.3018.\u00a0<\/em>PMID: 26963595<\/p>

Understanding the genetic liability to schizophrenia through the neuroepigenome<\/a><\/strong>
Fullard JF<\/strong>, Halene TB,\u00a0Giambartolomei C<\/strong>, Haroutunian V, Akbarian S,\u00a0Roussos P<\/strong>.Schizophr Res. 2016 Nov;177(1-3):115-124. doi: 10.1016\/j.schres.2016.01.039. Epub 2016 Jan 27. Review.\u00a0<\/em>PMID: 26827128<\/p>

Schizophrenia risk from complex variation of complement component 4<\/a><\/strong>
Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Daly MJ, Carroll MC, Stevens B, McCarroll SA.
Nature. 2016 Feb 11;530(7589):177-83. doi: 10.1038\/nature16549. Epub 2016 Jan 27.\u00a0<\/em>PMID: 26814963<\/p>

Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer\u2019s disease<\/a><\/strong>
Watson CT,\u00a0Roussos P<\/strong>, Garg P, Ho DJ, Azam N, Katsel PL, Haroutunian V, Sharp AJ.
Genome Med. 2016 Jan 19;8(1):5. doi: 10.1186\/s13073-015-0258-8.\u00a0<\/em>PMID: 26803900<\/p>

NeuN+ neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure<\/a><\/strong>
Halene TB, Kozlenkov A, Jiang Y, Mitchell AC, Javidfar B, Dincer A, Park R, Wiseman J, Croxson PL, Giannaris EL, Hof PR,\u00a0Roussos P<\/strong>, Dracheva S, Hemby SE, Akbarian S.
Schizophr Res. 2016 Feb;170(2-3):235-44. doi: 10.1016\/j.schres. 2015.12.016. Epub 2016 Jan 6.\u00a0<\/em>PMID: 26776227<\/p>

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness<\/a><\/strong>
Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, Werge T, Blackwood DH, Pato CN, Pato MT, Malhotra AK, O\u2019Donovan MC, Kendler KS, Fanous AH;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>.
Am J Med Genet B Neuropsychiatr Genet. 2016 Mar;171B(2):276-89. doi: 10.1002\/ajmg.b.32402. Epub 2015 Dec 11.\u00a0<\/em>PMID: 26663532<\/p>

Substantial DNA methylation differences between two major neuronal subtypes in human brain<\/a><\/strong>
Kozlenkov A, Wang M,\u00a0Roussos P<\/strong>, Rudchenko S, Barbu M, Bibikova M, Klotzle B, Dwork AJ, Zhang B, Hurd YL, Koonin EV, Wegner M, Dracheva S.
Nucleic Acids Res. 2016 Apr 7;44(6):2593-612. doi: 10.1093\/nar\/gkv1304. Epub 2015 Nov 26.\u00a0<\/em>PMID: 26612861<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2015\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2015\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington\u2019s Disease<\/a><\/strong>
Dong X, Tsuji J, Labadorf A,\u00a0Roussos P<\/strong>, Chen JF, Myers RH, Akbarian S, Weng Z.
PLoS One. 2015 Dec 4;10(12):e0144398. doi: 10.1371\/journal.pone. 0144398. eCollection 2015.\u00a0<\/em>PMID: 26636336<\/p>

The PsychENCODE project<\/a><\/strong>
PsychENCODE Consortium, Akbarian S, Liu C, Knowles JA, Vaccarino FM, Farnham PJ, Crawford GE, Jaffe AE, Pinto D, Dracheva S, Geschwind DH, Mill J, Nairn AC, Abyzov A, Pochareddy S, Prabhakar S, Weissman S, Sullivan PF, State MW, Weng Z, Peters MA, White KP, Gerstein MB, Amiri A, Armoskus C, Ashley-Koch AE, Bae T, Beckel-Mitchener A, Berman BP, Coetzee GA, Coppola G, Francoeur N, Fromer M, Gao R, Grennan K, Herstein J, Kavanagh DH, Ivanov NA, Jiang Y, Kitchen RR, Kozlenkov A, Kundakovic M, Li M, Li Z, Liu S, Mangravite LM, Mattei E, Markenscoff-Papadimitriou E, Navarro FC, North N, Omberg L, Panchision D, Parikshak N, Poschmann J, Price AJ, Purcaro M, Reddy TE,\u00a0Roussos P<\/strong>, Schreiner S, Scuderi S, Sebra R, Shibata M, Shieh AW, Skarica M, Sun W, Swarup V, Thomas A, Tsuji J, van Bakel H, Wang D, Wang Y, Wang K, Werling DM, Willsey AJ, Witt H, Won H, Wong CC, Wray GA, Wu EY, Xu X, Yao L, Senthil G, Lehner T, Sklar P, Sestan N.
Nat Neurosci. 2015 Dec;18(12):1707-12. doi: 10.1038\/nn.4156. Review. No abstract available.\u00a0<\/em>PMID: 26605881<\/p>

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis<\/a><\/strong>
Loh PR, Bhatia G, Gusev A, Finucane HK, Bulik-Sullivan BK, Pollack SJ;\u00a0Schizophrenia Working Group of Psychiatric Genomics Consortium,<\/strong>\u00a0de Candia TR, Lee SH, Wray NR, Kendler KS, O\u2019Donovan MC, Neale BM, Patterson N, Price AL.
Nat Genet. 2015 Dec;47(12):1385-92. doi: 10.1038\/ng.3431. Epub 2015 Nov 2.\u00a0<\/em>PMID: 26523775<\/p>

Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease<\/a><\/strong>
Won HH, Natarajan P, Dobbyn A, Jordan DM,\u00a0Roussos P<\/strong>, Lage K, Raychaudhuri S, Stahl E, Do R.
PLoS Genet. 2015 Oct 28;11(10):e1005622. doi: 10.1371\/journal. pgen.1005622. eCollection 2015 Oct.\u00a0<\/em>PMID: 26509271<\/p>

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder<\/a><\/strong>
Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, Stahl EA; Members of the International Cohort Collection for Bipolar Disorder (ICCBD), Chambert KD, Moran JL, Gordon-Smith K, Forty L, Green EK, Jones I, Jones L, Scolnick EM, Sklar P, Smoller JW, Lichtenstein P, Hultman C, Craddock N, Land\u00e9n M, Smoller JW, Perlis RH, Lee PH, Castro VM, Hoffnagle AG, Sklar P, Stahl EA, Purcell SM, Ruderfer DM, Charney AW,\u00a0Roussos P<\/strong>, Michele Pato CP, Medeiros H, Sobel J, Craddock N, Jones I, Forty L, Florio AD, Green E, Jones L, Gordon-Smith K, Landen M, Hultman C, Jureus A, Bergen S, McCarroll S, Moran J, Smoller JW, Chambert K, Belliveau RA.
Mol Psychiatry. 2016 Sep;21(9):1290-7. doi: 10.1038\/mp.2015.165. Epub 2015 Oct 27. Erratum in:\u00a0Mol Psychiatry. 2017 Aug;22(8):1223<\/a>.\u00a0<\/em>PMID: 26503763<\/p>

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores<\/a><\/strong>
Vilhj\u00e1lmsson BJ, Yang J, Finucane HK, Gusev A, Lindstr\u00f6m S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study, Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL.
Am J Hum Genet. 2015 Oct 1;97(4):576-92. doi: 10.1016\/j.ajhg. 2015.09.001.\u00a0<\/em>PMID: 26430803<\/p>

Genome-wide autozygosity is associated with lower general cognitive ability<\/a><\/strong>
Howrigan DP, Simonson MA, Davies G, Harris SE, Tenesa A, Starr JM, Liewald DC, Deary IJ, McRae A, Wright MJ, Montgomery GW, Hansell N, Martin NG, Payton A, Horan M, Ollier WE, Abdellaoui A, Boomsma DI, DeRosse P, Knowles EE, Glahn DC, Djurovic S, Melle I, Andreassen OA, Christoforou A, Steen VM, Hellard SL, Sundet K, Reinvang I, Espeseth T, Lundervold AJ, Giegling I, Konte B, Hartmann AM, Rujescu D,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Bitsios P, Donohoe G, Corley RP, Visscher PM, Pendleton N, Malhotra AK, Neale BM, Lencz T, Keller MC.
Mol Psychiatry. 2016 Jun;21(6):837-43. doi: 10.1038\/mp.2015.120. Epub 2015 Sep 22.\u00a0<\/em>PMID: 26390830<\/p>

The Relationship of Common Risk Variants and Polygenic Risk for Schizophrenia to Sensorimotor Gating<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Zouraraki C,\u00a0Fullard JF<\/strong>,\u00a0Karagiorga VE<\/strong>, Tsapakis EM, Petraki Z, Siever LJ, Lencz T, Malhotra A, Spanaki C, Bitsios P.
Biol Psychiatry. 2016 Jun 15;79(12):988-96. doi: 10.1016\/j.biopsych. 2015.06.019. Epub 2015 Jun 27.\u00a0<\/em>PMID: 26212897<\/p>

Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia<\/a><\/strong>
Rees E, Kirov G, Walters JT, Richards AL, Howrigan D, Kavanagh DH, Pocklington AJ, Fromer M, Ruderfer DM, Georgieva L, Carrera N, Gormley P, Palta P, Williams H, Dwyer S, Johnson JS,\u00a0Roussos P<\/strong>, Barker DD, Banks E, Milanova V, Rose SA, Chambert K, Mahajan M, Scolnick EM, Moran JL, Tsuang MT, Glatt SJ, Chen WJ, Hwu HG; Taiwanese Trios Exome Sequencing Consortium, Neale BM, Palotie A, Sklar P, Purcell SM, McCarroll SA, Holmans P, Owen MJ, O\u2019Donovan MC.
Transl Psychiatry. 2015 Jul 21;5:e607. doi: 10.1038\/tp.2015.99<\/em>. PMID:26196440<\/p>

Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophrenia<\/a><\/strong>
O\u2019Donovan SM, Hasselfeld K, Bauer D, Simmons M,\u00a0Roussos P<\/strong>, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.
Transl Psychiatry. 2015 Jun 9;5:e579. doi: 10.1038\/tp.2015.74.\u00a0<\/em>PMID: 26057049<\/p>

Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood<\/a><\/strong>
Hatzimanolis A, Bhatnagar P, Moes A, Wang R,\u00a0Roussos P<\/strong>, Bitsios P, Stefanis CN, Pulver AE, Arking DE, Smyrnis N, Stefanis NC, Avramopoulos D.
Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168B(5):392-401. doi: 10.1002\/ajmg.b.32323. Epub 2015 May 12.\u00a0<\/em>PMID: 25963331<\/p>

Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment<\/a><\/strong>
Trampush JW, Lencz T, Knowles E, Davies G, Guha S, Pe\u2019er I, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Ikeda M,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Scult M, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri A, Weinberger DR, Pendleton N, Iwata N, Darvasi A, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK.
Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168B(5):363-73. doi: 10.1002\/ajmg.b.32319. Epub<\/em>\u00a02015 May 7. PMID: 25951819<\/p>

The effects of the CACNA1C rs1006737 A\/G on affective startle modulation in healthy males<\/a><\/strong>
Pasparakis E, Koiliari E, Zouraraki C, Tsapakis EM,\u00a0Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Eur Psychiatry. 2015 Jun;30(4):492-8. doi: 10.1016\/j.eurpsy. 2015.03.004. Epub 2015 Apr 1.\u00a0<\/em>PMID: 25841664<\/p>

Validation of electronic health record phenotyping of bipolar disorder cases and controls<\/a><\/strong>
Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW;\u00a0International Cohort Collection for Bipolar Disorder Consortium<\/strong>.
Am J Psychiatry. 2015 Apr;172(4):363-72. doi: 10.1176\/appi.ajp. 2014.14030423. Epub 2014 Dec 12.\u00a0<\/em>PMID: 25827034<\/p>

Integration of gene expression and GWAS results supports <\/strong>involvement of calcium <\/strong>signaling in Schizophrenia<\/strong><\/a>
Hertzberg L, Katsel P,\u00a0Roussos P<\/strong>, Haroutunian V, Domany E.
Schizophr Res. 2015 May;164(1-3):92-9. doi: 10.1016\/j.schres. 2015.02.001. Epub 2015 Feb 20.\u00a0<\/em>PMID: 25702973<\/p>

Genomic and network patterns of schizophrenia genetic variation in human evolutionary accelerated regions<\/strong>
<\/a>Xu K, Schadt EE, Pollard KS,\u00a0Roussos P<\/strong>, Dudley JT.
Mol Biol Evol. 2015 May;32(5):1148-60. doi: 10.1093\/molbev\/msv031. Epub 2015 Feb 12.<\/em>\u00a0PMID: 25681384<\/p>

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies<\/strong>
<\/a>Bulik-Sullivan BK, Loh PR, Finucane HK, Ripke S, Yang J;<\/span>\u00a0<\/span>Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>, Patterson N, Daly MJ, Price AL, Neale BM.<\/span>Nat Genet. 2015 Mar;47(3):291-5. doi: 10.1038\/ng.3211. Epub 2015 Feb 2.\u00a0<\/em>PMID: 25642630<\/p>

The relationship between dopamine receptor D1 and cognitive performance<\/strong>
<\/a>Tsang J<\/strong>,\u00a0Fullard JF<\/strong>, Giakoumaki SG, Katsel P, Katsel P,\u00a0Karagiorga VE<\/strong>, Greenwood TA, Braff DL, Siever LJ, Bitsios P, Haroutunian V,\u00a0Roussos P<\/strong>.
NPJ Schizophr. 2015 Mar 4;1:14002. doi: 10.1038\/npjschz.2014.2. eCollection 2015. Erratum in:\u00a0NPJ Schizophr. 2015;1:15018<\/a>.\u00a0<\/em>PMID: 27336024<\/p>

The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer\u2019s dementia<\/a><\/strong>
Roussos P<\/strong>, Katsel P, Fam P, Tan W, Purohit DP, Haroutunian V.
Alzheimers Dement. 2015 Oct;11(10):1163-70. doi: 10.1016\/j.jalz. 2014.10.013. Epub 2014 Dec 9.\u00a0<\/em>PMID: 25499537<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2014\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2014\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition<\/a><\/strong>
Bharadwaj R, Peter CJ, Jiang Y,\u00a0Roussos P<\/strong>, Vogel-Ciernia A, Shen EY, Mitchell AC, Mao W, Whittle C, Dincer A, Jakovcevski M, Pothula V, Rasmussen TP, Giakoumaki SG, Bitsios P, Sherif A, Gardner PD, Ernst P, Ghose S, Sklar P, Haroutunian V, Tamminga C, Myers RH, Futai K, Wood MA, Akbarian S.
Neuron. 2014 Dec 3;84(5):997-1008. doi: 10.1016\/j.neuron. 2014.10.032. Epub 2014 Nov 13.\u00a0<\/em>PMID: 25467983<\/p>

A role for noncoding variation in schizophrenia<\/a><\/strong>
Roussos P<\/strong>, Mitchell AC,\u00a0Voloudakis G, Fullard JF<\/strong>, Pothula VM,\u00a0Tsang J<\/strong>, Stahl EA, Georgakopoulos A, Ruderfer DM, Charney A, Okada Y, Siminovitch KA, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Plenge RM, Raychaudhuri S, Fromer M, Purcell SM, Brennand KJ, Robakis NK, Schadt EE, Akbarian S, Sklar P.
Cell Rep. 2014 Nov 20;9(4):1417-29. doi: 10.1016\/j.celrep. 2014.10.015. Epub 2014 Nov 6.\u00a0<\/em>PMID: 25453756<\/p>

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases<\/a><\/strong>
Gusev A, Lee SH, Trynka G, Finucane H, Vilhj\u00e1lmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium, K\u00e4hler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL;\u00a0Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>; SWE-SCZ Consortium.
Am J Hum Genet. 2014 Nov 6;95(5):535-52. doi: 10.1016\/j.ajhg. 2014.10.004. Epub 2014 Nov 6.\u00a0<\/em>PMID: 25439723<\/p>

The future of neuroepigenetics in the human brain<\/a><\/strong>
Mitchell A,\u00a0Roussos P<\/strong>, Peter C, Tsankova N, Akbarian S.
Prog Mol Biol Transl Sci. 2014;128:199-228. doi: 10.1016\/ B978-0-12-800977-2.00008-5. Review.\u00a0<\/em>PMID: 25410546<\/p>

Myelination, oligodendrocytes, and serious mental illness<\/a><\/strong>
Haroutunian V, Katsel P,\u00a0Roussos P<\/strong>, Davis KL, Altshuler LL, Bartzokis G.
Glia. 2014 Nov;62(11):1856-77. doi: 10.1002\/glia.22716. Epub 2014 Jul 23. Review.\u00a0<\/em>PMID: 25056210<\/p>

Biological insights from 108 schizophrenia-associated genetic loci<\/a><\/strong>
Schizophrenia Working Group of the Psychiatric Genomics Consortium<\/strong>.
Nature. 2014 Jul 24;511(7510):421-7. doi: 10.1038\/nature13595. Epub 2014 Jul 22.\u00a0<\/em>PMID: 25056061<\/p>

A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicid<\/strong>e<\/a>
Di Narzo AF, Kozlenkov A,\u00a0Roussos P<\/strong>, Hao K, Hurd Y, Lewis DA, Sibille E, Siever LJ, Koonin E, Dracheva S.
Hum Mol Genet. 2014 Sep 15;23(18):4801-13. doi: 10.1093\/hmg\/ddu195. Epub 2014 Apr 29.\u00a0<\/em>PMID: 24781207<\/p>

The CSMD1 genome-wide associated schizophrenia risk variant rs10503253 affects <\/strong>general cognitive ability and executive function in healthy males<\/strong><\/a>
Koiliari E,\u00a0Roussos P<\/strong>, Pasparakis E, Lencz T, Malhotra A, Siever LJ, Giakoumaki SG, Bitsios P.
Schizophr Res. 2014 Apr;154(1-3):42-7. doi: 10.1016\/j.schres. 2014.02.017. Epub 2014 Mar 11.\u00a0<\/em>PMID: 24630139<\/p>

Schizophrenia: susceptibility genes and oligodendroglial and myelin related abnormalities<\/a><\/strong>
Roussos P<\/strong>, Haroutunian V.
Front Cell Neurosci. 2014 Jan 21;8:5. doi: 10.3389\/fncel.2014.00005. eCollection 2014. Review.\u00a0<\/em>PMID: 24478629<\/p>

A polygenic burden of rare disruptive mutations in schizophrenia<\/a><\/strong>
Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N,\u00a0Roussos P<\/strong>, O\u2019Dushlaine C, Chambert K, Bergen SE, K\u00e4hler A, Duncan L, Stahl E, Genovese G, Fern\u00e1ndez E, Collins MO, Komiyama NH, Choudhary JS, Magnusson PK, Banks E, Shakir K, Garimella K, Fennell T, DePristo M, Grant SG, Haggarty SJ, Gabriel S, Scolnick EM, Lander ES, Hultman CM, Sullivan PF, McCarroll SA, Sklar P.
Nature. 2014 Feb 13;506(7487):185-90. doi: 10.1038\/nature12975. Epub 2014 Jan 22.\u00a0<\/em>PMID: 24463508<\/p>

De novo mutations in schizophrenia implicate synaptic networks<\/a><\/strong>
Fromer M, Pocklington AJ, Kavanagh DH, Williams HJ, Dwyer S, Gormley P, Georgieva L, Rees E, Palta P, Ruderfer DM, Carrera N, Humphreys I, Johnson JS,\u00a0Roussos P<\/strong>, Barker DD, Banks E, Milanova V, Grant SG, Hannon E, Rose SA, Chambert K, Mahajan M, Scolnick EM, Moran JL, Kirov G, Palotie A, McCarroll SA, Holmans P, Sklar P, Owen MJ, Purcell SM, O\u2019Donovan MC.
Nature. 2014 Feb 13;506(7487):179-84. doi: 10.1038\/nature12929.<\/em>\u00a0Epub 2014 Jan 22. PMID: 24463507<\/p>

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)<\/a><\/strong>
Lencz T, Knowles E, Davies G, Guha S, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, R\u00e4ikk\u00f6nen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Ikeda M,\u00a0Roussos P<\/strong>, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Donohoe G, Morris D, Corvin A, Gill M, Pendleton N, Iwata N, Darvasi A, Bitsios P, Rujescu D, Lahti J, Hellard SL, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK.
Mol Psychiatry. 2014 Feb;19(2):168-74. doi: 10.1038\/mp.2013.166. Epub 2013 Dec 17.\u00a0<\/em>PMID: 24342994<\/p>

Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites<\/a><\/strong>
Kozlenkov A,\u00a0Roussos P<\/strong>, Timashpolsky A, Barbu M, Rudchenko S, Bibikova M, Klotzle B, Byne W, Lyddon R, Di Narzo AF, Hurd YL, Koonin EV, Dracheva S.
Nucleic Acids Res. 2014 Jan;42(1):109-27. doi: 10.1093\/nar\/gkt838. Epub 2013 Sep 20.\u00a0<\/em>PMID: 24057217<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2013\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2013\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Cognitive and personality analysis of startle reactivity in a large cohort of healthy males<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Tsapakis EM, Koiliari E, Pasparakis E, Zouraraki C, Bitsios P.
Biol Psychol. 2013 Dec;94(3):582-91. doi: 10.1016\/j.biopsycho. 2013.09.005. Epub 2013 Sep 16.\u00a0<\/em>PMID: 24051230<\/p>

Schizoid personality disorder<\/a><\/strong>
Triebwasser J, Chemerinski E,\u00a0Roussos P<\/strong>, Siever LJ.
J Pers Disord. 2012 Dec;26(6):919-26. doi: 10.1521\/pedi. 2012.26.6.919. Review<\/em>. PMID: 23281676<\/p>

Convergent findings for abnormalities of the NF-\u03baB signaling pathway in schizophrenia<\/a><\/strong>
Roussos P<\/strong>, Katsel P, Davis KL, Giakoumaki SG, Lencz T, Malhotra AK, Siever LJ, Bitsios P, Haroutunian V.
Neuropsychopharmacology. 2013 Feb;38(3):533-9. doi: 10.1038\/npp.2012.215. Epub 2012 Nov 7. Erratum in: Neuropsychopharmacology. 2013 Mar;38(4):699. Lencz, Todd [added]; Malhotra, Anil K [added].\u00a0<\/em>PMID: 23132271<\/p>

Sub-optimal parenting is associated with schizotypic and anxiety personality traits in adulthood<\/strong>
<\/a>Giakoumaki SG,\u00a0Roussos P<\/strong>, Zouraraki C, Spanoudakis E, Mavrikaki M, Tsapakis EM, Bitsios P.
Eur Psychiatry. 2013 May;28(4):254-60. doi: 10.1016\/j.eurpsy. 2012.07.002. Epub 2012 Oct 10.\u00a0<\/em>PMID: 23062835<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2012\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2012\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Anterior limb of the internal capsule in schizotypal personality disorder: fiber-tract counting, volume, and anisotropy<\/a><\/strong>
Hazlett EA, Collazo T, Zelmanova Y, Entis JJ, Chu KW, Goldstein KE,\u00a0Roussos P<\/span>, Haznedar MM, Koenigsberg HW, New AS, Buchsbaum MS, Hershowitz JP, Siever LJ, Byne W.
Schizophr Res. 2012 Nov;141(2-3):119-27. doi: 10.1016\/j.schres. 2012.08.022. Epub 2012 Sep 18.\u00a0<\/em>PMID: 22995934<\/p>

CACNA1C as a risk factor for schizotypal personality disorder and schizotypy in healthy individuals<\/strong><\/a>
Roussos P<\/span>, Bitsios P, Giakoumaki SG, McClure MM, Hazlett EA, New AS, Siever LJ.
Psychiatry Res. 2013 Mar 30;206(1):122-3. doi: 10.1016\/j.psychres. 2012.08.039. Epub 2012 Sep 15. No abstract available.\u00a0<\/em>PMID: 22985546<\/p>

Schizotypal personality disorder<\/strong><\/a>
Chemerinski E, Triebwasser J,\u00a0Roussos P<\/span>, Siever LJ.
J Pers Disord. 2013 Oct;27(5):652-79. doi: 10.1521\/pedi_ 2012_26_053. Epub 2012 Aug 28.\u00a0<\/em>PMID: 22928856<\/p>

Paranoid personality disorder<\/a><\/strong>
Triebwasser J, Chemerinski E,\u00a0Roussos P<\/span>, Siever LJ.
J Pers Disord. 2013 Dec;27(6):795-805. doi: 10.1521\/pedi_ 2012_26_055. Epub 2012 Aug 28. Review.\u00a0<\/em>PMID: 22928850<\/p>

A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples<\/strong><\/a>
Roussos P<\/span>, Katsel P, Davis KL, Siever LJ, Haroutunian V.
Arch Gen Psychiatry. 2012 Dec;69(12):1205-13. doi: 10.1001\/ archgenpsychiatry.2012.704.\u00a0<\/em>PMID: 22868662<\/p>

Cannabis-dependence risk relates to synergism between neuroticism and proenkephalin SNPs associated with amygdala gene expression: case-control study<\/a><\/strong>
Jutras-Aswad D, Jacobs MM, Yiannoulos G,\u00a0Roussos P<\/span>, Bitsios P, Nomura Y, Liu X, Hurd YL.
PLoS One. 2012;7(6):e39243. doi: 10.1371\/journal.pone.0039243. Epub 2012 Jun 22.\u00a0<\/em>PMID:22745721<\/p>

Transcription factor 4 as an important determinant of gating function in schizophrenia<\/a><\/strong>
Roussos P<\/span>.
Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):5915-6. doi:10.1073\/pnas. 1203675109. Epub 2012 Apr 5. No abstract available.\u00a0<\/em>PMID: 22492968<\/p>

Molecular and genetic evidence for abnormalities in the nodes of Ranvier in schizophrenia<\/a><\/strong>
Roussos P<\/span>, Katsel P, Davis KL, Bitsios P, Giakoumaki SG, Jogia J, Rozsnyai K, Collier D, Frangou S, Siever LJ, Haroutunian V.
Arch Gen Psychiatry. 2012 Jan;69(1):7-15. doi: 10.1001\/archgenpsychiatry. 2011.110. Epub 2011 Sep 5.\u00a0<\/em>PMID: 21893642<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2011\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2011\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Sustained attention and working memory deficits follow a familial pattern in schizophrenia<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Pallis EG, Bitsios P.
Arch Clin Neuropsychol. 2011 Nov;26(7):687-95. doi: 10.1093\/arclin\/acr060. Epub 2011 Aug 3.\u00a0<\/em>PMID: 21813556<\/p>

The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Georgakopoulos A, Robakis NK, Bitsios P.
Bipolar Disord. 2011 May;13(3):250-9. doi: 10.1111\/j.1399-5618. 2011.00924.x.\u00a0<\/em>PMID: 21676128<\/p>

Tolcapone, COMT polymorphisms and pharmacogenomic treatment of schizophrenia<\/a><\/strong>
Bitsios P,\u00a0Roussos P<\/strong>.
Pharmacogenomics. 2011 Apr;12(4):559-66. doi: 10.2217\/pgs.10.206\u00a0<\/em>PMID: 21521027<\/p>

The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Adamaki E, Georgakopoulos A, Robakis NK, Bitsios P.
Neuropsychopharmacology. 2011 Jul;36(8):1677-88. doi: 10.1038\/npp.2011.49. Epub 2011 Apr 6. Erratum in: Neuropsychopharmacology. 2011 Oct;36(11):2370. Anastasios, Georgakopoulos [corrected to Georgakopoulos, Anastasios]; Nikos, Robakis K [corrected to Robakis, Nikos K].\u00a0<\/em>PMID: 21471957<\/p>

Astrocyte and glutamate markers in the superficial, deep, and white matter layers of the anterior cingulate gyrus in schizophrenia<\/a><\/strong>
Katsel P, Byne W,\u00a0Roussos P<\/strong>, Tan W, Siever L, Haroutunian V.
Neuropsychopharmacology. 2011 May;36(6):1171-7. doi: 10.1038\/npp.2010.252. Epub 2011 Jan 26.\u00a0<\/em>PMID: 21270770<\/p>

The influence of schizophrenia-related neuregulin-1 polymorphisms on sensorimotor gating in healthy males<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Adamaki E, Bitsios P.
Biol Psychiatry. 2011 Mar 1;69(5):479-86. doi: 10.1016\/j.biopsych. 2010.09.009. Epub 2010 Oct 30.\u00a0<\/em>PMID: 21035784<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2010\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2010\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Cognitive and emotional processing associated with the Season of Birth and dopamine D4 receptor gene<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Neuropsychologia. 2010 Nov;48(13):3926-33. doi: 10.1016\/j.neuropsychologia. 2010.09.021. Epub 2010 Sep 25.\u00a0<\/em>PMID: 20875435<\/p>

Low baseline startle and deficient affective startle modulation in remitted bipolar disorder patients and their unaffected siblings<\/a><\/strong>
Giakoumaki SG, Bitsios P, Frangou S,\u00a0Roussos P<\/strong>, Aasen I, Galea A, Kumari V.
Psychophysiology. 2010 Jul 1;47(4):659-68. doi: 10.1111\/j.1469- 8986.2010.00977.x. Epub 2010 Mar 11.\u00a0<\/em>PMID: 20233338<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2009\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2009\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c\/g polymorphism<\/strong><\/a>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Biol Psychiatry. 2009 Dec 1;66(11):997-1004. doi: 10.1016\/j.biopsych.2009.07.008. Epub 2009 Aug 22.\u00a0<\/em>PMID: 19699472<\/p>

Cognitive and emotional processing in high novelty seeking associated with the L-DRD4 genotype<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Neuropsychologia. 2009 Jun;47(7):1654-9. doi: 10.1016\/ j.neuropsychologia.2009.02.005.Epub 2009 Feb 11.<\/em>PMID: 19397860<\/p>

Comparison of ketanserin, buspirone and propranolol on arousal, pupil size and autonomic function in healthy volunteers<\/a><\/strong>
Koudas V, Nikolaou A, Hourdaki E, Giakoumaki SG,\u00a0Roussos P<\/strong>, Bitsios P.
Psychopharmacology (Berl). 2009 Jul;205(1):1-9. doi: 10.1007\/s00213-009-1508-5. Epub 2009 Mar 14.\u00a0<\/em>PMID: 19288084<\/p>

A risk PRODH haplotype affects sensorimotor gating, memory, schizotypy, and anxiety in healthy male subjects<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Biol Psychiatry. 2009 Jun 15;65(12):1063-70. doi: 10.1016\/ j.biopsych.2009.01.003. Epub 2009 Feb 20.\u00a0<\/em>PMID: 19232576<\/p>

Azoles and antidepressants: a mini-review of the tolerability of co-administration<\/a><\/strong>
Roussos P<\/strong>, Lewis RE, Kontoyiannis DP.
Mycoses. 2009 Sep;52(5):433-9. doi: 10.1111\/j.1439-0507.2008. 01677.x. Epub 2009 Jan 21. Review.\u00a0<\/em>PMID: 19207836<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2008\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2008\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Bitsios P.
Neuropsychopharmacology. 2008 Dec;33(13):3058-68. doi: 10.1038\/npp.2008.82. Epub 2008 Jun 4.\u00a0<\/em>PMID: 18536698<\/p>

The dopamine D(3) receptor Ser9Gly polymorphism modulates prepulse inhibition of the acoustic startle reflex<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Bitsios P.
Biol Psychiatry. 2008 Aug 1;64(3):235-40. doi: 10.1016\/j.biopsych. 2008.01.020. Epub 2008 Mar 5.\u00a0<\/em>PMID: 18325483<\/p>

Prepulse inhibition of the startle reflex depends on the catechol O-methyltransferase Val158Met gene polymorphism<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Rogdaki M, Pavlakis S, Frangou S, Bitsios P.
Psychol Med. 2008 Nov;38(11):1651-8. doi: 10.1017\/ S0033291708002912. Epub 2008 Feb 8.\u00a0<\/em>PMID: 18261249<\/p>

Planning, decision-making and the COMT rs4818 polymorphism in healthy males<\/a><\/strong>
Roussos P<\/strong>, Giakoumaki SG, Pavlakis S, Bitsios P.
Neuropsychologia. 2008 Jan 31;46(2):757-63. Epub 2007 Oct 22.\u00a0<\/em>PMID: 18037454<\/p>

The 5-min pupillary alertness test is sensitive to modafinil: a placebo controlled study in patients with sleep apnea<\/a><\/strong>
Nikolaou A, Schiza SE, Giakoumaki SG,\u00a0Roussos P<\/strong>, Siafakas N, Bitsios P.
Psychopharmacology (Berl). 2008 Feb;196(2):167-75. Epub 2007 Sep 25.\u00a0<\/em>PMID: 17899016<\/p>

[\/et_pb_toggle][et_pb_toggle title=\"2007\" icon_color=\"#00aeef\" disabled_on=\"off|off|off\" admin_label=\"2007\" _builder_version=\"4.9.0\" title_text_color=\"#00a6e5\" body_text_color=\"#555555\" border_radii=\"on|6px|6px|6px|6px\" border_color_all=\"#00aeef\" saved_tabs=\"all\"]<\/p>

Disruption of prepulse inhibition of the startle reflex by the preferential D(3) agonist ropinirole in healthy males<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Frangou S, Bitsios P.
Psychopharmacology (Berl). 2007 Oct;194(3):289-95. Epub 2007 Jun 20.\u00a0<\/em>PMID: 17579840<\/p>

Evidence of disrupted prepulse inhibition in unaffected siblings of bipolar disorder patients<\/a><\/strong>
Giakoumaki SG,\u00a0Roussos P<\/strong>, Rogdaki M, Karli C, Bitsios P, Frangou S.
Biol Psychiatry. 2007 Dec 15;62(12):1418-22. Epub 2007 May 3.\u00a0<\/em>PMID: 17481589<\/p>

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