Discovering and Describing New De-Identified Cohorts of Patients with i2b2 Framework

The Mount Sinai Scientific Computing and Data Science team has launched training resources via PEAK to take researchers step-by-step through the i2b2 (Informatics for Integrating Biology & the Bedside) program, preparing them to take advantage of this cost-effective and efficient way to identify patients for many types of clinical and translational research. The i2b2 framework was developed through NIH funding to make research cohort discovery possible through the integration, standardization, and analysis of heterogeneous data from electronic health record systems. The implementation of i2b2 at the Mount Sinai Health System is supported by ConduITS, the Institutes for Translational Sciences and Mount Sinai’s CTSA (an NIH|NCATS Clinical and Translational Science Award).

To access the training on PEAK, simply click here, or head over to, sign in and search for “i2b2.” It’s also available through clicking on Online Courses, navigating to Research and clicking on the i2b2 Tutorial.

With an easy to use, drag-and-drop interface, i2b2 enables researchers to query a repository of patient information gathered from multiple sources throughout the Mount Sinai Health System, including electronic medical records, lab results, and demographic data. Using de-identified data, investigators can determine potential cohorts of interest for later obtaining identified or limited data sets with Institutional Review Board (IRB) approval. For more information about the IRB approval process, contact

This web-based tool works on Windows and Mac, on multiple browsers (Firefox, Internet Explorer, Safari, and Google Chrome) within the Mount Sinai network (on campus or via VPN). Data is uploaded from the Mount Sinai Data Warehouse on a regular basis, but only de-identified data can be accessed through the web client. Mount Sinai researchers can perform queries at

Please email with questions or comments.


Must See Videos and Podcasts for Human Subjects Researchers

The Grants and Contracts Office (GCO) strongly recommends that human subjects researchers take advantage of educational resources issued by the National Institutes of Health (NIH) to inform grants applications submitted for due dates on or after January 25, 2018.

A primary component of NIH’s initiative to enhance the stewardship of clinical trials is the creation of a new application form that consolidates all Human Subjects and Clinical Trial related information into one place, and also expands the information required for studies that meet the NIH definition of a clinical trial. This new form will be included in the new FORMS-E Application Packages and will be required for all applications with due dates on or after January 25, 2018.

To support this endeavor for Mount Sinai Health System (MSHS) researchers, the GCO would like to highlight the following NIH resources:

To learn more about the new Human Subjects and Clinical Trial Information form which will be included in grant application packages and contract for all human subjects and/or clinical trial research applications beginning for January 25, 2018 due dates, visit the NIH New Human Subjects and Clinical Trial Information Form web site.

For more information about conducting human subjects research at MSHS, please contact the Program for the Protection of Human Subjects.

For more information about NIH grant submissions at MSHS, please click here for a listing of Departmental Grants Specialists at the GCO who can assist you.


Yiannis Ioannou PhD Honored as the 2017 Mount Sinai Inventor of the Year

The 2017 Mount Sinai Inventor of the Year Award was presented to Yiannis Ioannou, PhD  at the SinaInnovations Awards Ceremony on October 16 for his groundbreaking research and entrepreneurial spirit in bringing his research “from bench to bedside.”

Dr. Ioannou’s work in lysosomal storage diseases led to the first ever treatment for Fabry disease, in collaboration with Robert Desnick, MD, PhD, and the discovery of small-molecules that may serve as the basis for novel therapies for the treatment of numerous lysosomal storage diseases, including those with severe neurodegenerative effects. Yiannis’ commitment to seeing these discoveries translated into products that benefit patients and his tireless effort as an inventor-collaborator with Mount Sinai Innovation Partners culminated in the launch of a new company in partnership with institutional investors in early 2017.

The Mount Sinai Inventor of the Year Award was created to recognize individual or collaborative investigators in the Mount Sinai Health System. The award offers $10,000 to the recipient whose research is making, or has the potential to make, significant positive and product-driven impacts on health. The 2016 recipient was Dennis Charney, MD, Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai and President for Academic Affairs for the Mount Sinai Health System.

Watch the video highlighting Dr. Ioannou’s research endeavors and his inspiration for commercializing his technology with MSIP.


Department of Corporate and Foundation Relations Announces Funding Opportunities

Department of Corporate and Foundation Relations Announces Funding Opportunities

The Department of Corporate and Foundation Relations of the Mount Sinai Development Office provides this curated list of funding opportunities to find faculty who may be interested and to provide assistance with the application process. Please see below for some of their upcoming deadlines, and check out their website for more information:

Please note – if you are interested in general funding opportunities (not a specific RFP listed here), please fill out the form linked on the site with your inquiry.

Postdoctoral Enrichment Program – Burroughs Wellcome Fund

Postdoctoral Enrichment Program (PDEP) provides a total of $60,000 over three years to support the career development activities for underrepresented minority postdoctoral fellows in a degree-granting institution (an institution includes its affiliated graduate and medical schools, hospitals and research institutions) in the United States or Canada whose training and professional development are guided by mentors committed to helping them advance to stellar careers in biomedical or medical research.

  • Generally, up to 12 awards will be granted for enrichment activities annually. This grant is meant to supplement the training of postdocs whose research activities are already supported. It is not a research grant.
  • The program provides a total of $60,000 over three years as follows:
    • Year one: $20,000 will be granted to support enrichment activities of the postdoctoral fellow ($10,000 for research supplies or equipment uniquely required to enhance the postdoctoral fellow’s research and $10,000 for education and training, including for mentors in the research lab where the postdoctoral fellow is assigned.)
    • Year two: $20,000 (same allocation as year one)
    • Year three: $20,000 will be granted to help the postdoctoral fellow advance research efforts towards the professoriate.  The funds must be used to develop independent, innovative areas of research.
  • Deadline: January 16, 2018 by 4 PM EST

 Broad Medical Research Program @ Crohn’s and Colitis Foundation of America

Research grants are available for innovative proposals that will lead to improvements in the prevention, diagnosis, or therapy of Crohn’s disease or ulcerative colitis. BMRP-CCFA especially supports research that can be readily translated to improve the care of human IBD in the near future.

  • Rolling Deadline: Please email if you are interested in this rolling deadline program, and the Department of Corporate and Foundation Relations will facilitate approaching the foundation.


Centralized FedEx Service Established

The Office of Research Services is pleased to announce that its piloted process for shipping biological substances for clinical trials via FedEx at Icahn School of Medicine at Mount Sinai has facilitated nearly 2000 shipments since its pilot in April 2016. Mailroom Assistant Manager Sybil Allen reports, “the program has been a great success, and I work very closely with the Manager at FedEx, who makes sure that the packages are picked up on time.” Due to consistently positive feedback and increasing traffic, growing to an average of 40 packages per week in recent weeks, this service is now available on an ongoing basis.

Clinical trial shipments with a FedEx pre-paid label can be dropped off at the mailroom by 4:00pm for same-day shipping. Any FedEx shipments after 4:00pm will continue to be the responsibility of the research team. The mailroom is located on the SB Level of 5 East 98th Street, and Assistant Manager Sybil Allen can be reached at (212) 241-6161 (x46161).

For all shipments, the study team must ensure the shipper is IATA Certified and that the label and packaging are in compliance with current regulations for shipping biological substances ( If you have any questions about shipping biological substances, please email Mark Matthews, Director of Environmental Health and Safety, at

If you have any questions regarding this process, please open a ticket with your question to the Office of Research Services via Research 411.


InfoEd Upgrade Prompts GCO Advice to Research Community

Some of us may strive to be like a robot achieving our goals in the most efficient and systematic way possible. Others may resemble this robot before drinking their morning coffee. Wherever we may fall in this inner and outer robotic spectrum, please be aware that with the new version of InfoEd that went live on Tuesday, November 21, adjustments need to be made in our inner auto-robotic settings as some of the InfoEd fields and tabs have changed. You may also be pleasantly surprised with InfoEd’s enhanced functionality in the budget section.

The below highlights significant changes and increased functionality. In addition, Research Information Technology posted a slide set with screenshots and a corresponding podcast. They plan on updating training material as needed, so please do check back on the Research IT InfoEd Instructions web page for the latest updates.

  • Initial Set Up Tab: “Step 3 Selecting a Sponsor”
    Removal of sponsor drop down menu and “Preferred” box with simple typing data entry box.
  • Tabs that Remain the Same or Little Change
    • Brief Lay Summary
    • Research or Program Plan and Progress Report Tabs
    • Classification Codes
    • Finalize
  • Tabs that Are Different
    • Set Up
    • Personnel
    • Budget
    • Internal Documents: Location of the “eForm” Moved to a Stand Alone Tab
  • Personnel Tab: When Adding Personnel, the Default is Key Personnel
    Please be sure to change the default in the provided drop down menu if you are adding someone other than key personnel.
  • Subawards Are Added Differently
  • Budget Tabs: Option to Enter Entire Budget onto the Main Budget Tab or into Individual Tabs by Period
  • Budget Tab > Personnel: Defaults to “Person Months” Rather Than “% Effort”
    You can change the default to “% effort” if you wish.
  • Budget Tab > Personnel > Fringe Benefits: Option to Use Sinai’s Rates or Manually Data Enter the Amount
  • Budget Tab: Entry of $ Amounts in Y1 in “Personnel” and “Non-Personnel” sections -Automatically Adds the Same Costs to Future Years if Future Years are Included.
    Easy to remove or change the costs if needed.
  • Modular Budget Tab – Defaults to Increments of 10, that is 10 Modules x $25,000 = $250,000
    If your modular budget is not a request for $250,000 in direct costs per year, please do change to the appropriate number of modules.

Please open a Ticket with Research IT if you need technical assistance with your proposal.