[et_pb_section fb_built=”1″ fullwidth=”on” admin_label=”WELCOME TO THE RENDL LAB” _builder_version=”4.9.0″][et_pb_fullwidth_header title=”WELCOME TO THE RENDL LAB” text_orientation=”center” admin_label=”WELCOME TO THE RENDL LAB” _builder_version=”4.9.0″ _module_preset=”default” title_font=”||||||||” title_text_align=”center” title_font_size=”60px” title_letter_spacing=”4px” title_line_height=”1.7em” background_color=”RGBA(0,0,0,0)” background_image=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2022\/08\/Stalled-follicles_03MR-2560×1440-1.jpg” parallax=”on” parallax_method=”on” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|desktop” height=”550px” max_height=”1000px” custom_margin=”-32px||||false|false” custom_padding=”150px|||||” title_font_size_tablet=”” title_font_size_phone=”50px” title_font_size_last_edited=”on|desktop” title_line_height_tablet=”1.9em” title_line_height_phone=”1.1em” title_line_height_last_edited=”on|phone” background_last_edited=”on|desktop” background_size_tablet=”cover” title_text_shadow_style=”preset3″][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”FORMATION AND FUNCTION OF STEM CELL NICHES” _builder_version=”3.22″ custom_padding=”0px|0|0px|0px|false|false”][et_pb_row _builder_version=”4.9.0″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”960px” module_alignment=”center” custom_padding=”0px|||||”][et_pb_column type=”4_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text admin_label=”FORMATION AND FUNCTION OF STEM CELL NICHES” _builder_version=”4.9.0″ header_letter_spacing=”1px” min_height=”349.7px” custom_margin=”40px|||||” custom_padding=”0px|||||”]<\/p>\n
Stem cells and their immediate environment, also called stem cell niche, are critical for the growth and continuous renewal of our organs, and are also key for new growth and repair during regeneration. Unlocking the secrets of how specialized niche cells operate to activate stem cells and progenitors holds great promise for regenerative medicine. <\/span><\/p>\n Our laboratory aims to answer these fundamental questions in stem cell biology by utilizing the hair follicle mini-organ as a powerful model system. Deciphering how niche cells govern stem cell and progenitor functions in the hair follicle will also provide a rational basis for developing hair regenerative therapies. <\/span>Fundamental questions towards this goal are:<\/span><\/p>\n 1) How do niche cells acquire the stem cell-inducing properties?<\/span><\/p>\n 2) What are the niche signals that control tissue growth and regeneration?<\/span><\/p>\n 3) How do niche cells control tissue reorganization?<\/span><\/p>\n [\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/research\/” button_text=”FIND OUT MORE” button_alignment=”center” admin_label=”Button: Find out more” _builder_version=”4.9.0″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_border_width=”2px” button_border_radius=”34px” button_letter_spacing=”1px”][\/et_pb_button][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-content\/uploads\/sites\/292\/2023\/09\/230525_Alexias-Goodbye_IMG-1666_02MR-2560×1600-1.jpg” title_text=”Lab in the Park, May 2023″ force_fullwidth=”on” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.0″ custom_margin=”42px|||||” custom_padding=”20px|||||” hover_enabled=”0″ sticky_enabled=”0″][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" FORMATION AND FUNCTION OF STEM CELL NICHES Stem cells and their immediate environment, also called stem cell niche, are critical for the growth and continuous renewal of our organs, and are also key for new growth and repair during regeneration. Unlocking the secrets of how specialized niche cells operate to activate stem cells and progenitors […]<\/p>\n","protected":false},"author":320,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-json\/wp\/v2\/users\/320"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":57,"href":"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"predecessor-version":[{"id":1114,"href":"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-json\/wp\/v2\/pages\/9\/revisions\/1114"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/rendl-lab\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}