{"id":8,"date":"2015-08-05T15:01:41","date_gmt":"2015-08-05T15:01:41","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/ramirezlab\/?page_id=8"},"modified":"2021-08-25T14:58:53","modified_gmt":"2021-08-25T14:58:53","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-52\" src=\"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/wp-content\/uploads\/sites\/100\/2015\/08\/PubMed-Logo.png\" alt=\"\" width=\"67\" height=\"23\" \/>\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Ramirez%20F%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=26189658\">Search PubMed for articles<\/a><\/p>\n<p>Selected Publications:<\/p>\n<p><strong>2014<\/strong><\/p>\n<p>Cook J.R., Carta L., Benard L., Chemaly E.R., Chiu E., Rao S.K., Hampton T.G., Yurchenco P., Costa K.D., Hajjar R.J., <strong>Ramirez F<\/strong>. (2014) Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome. <strong>J. Clin. Invest<\/strong>. 124:1329-1339.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>2015<\/strong><\/p>\n<p>Cook J.R., Clayton N.P., Carta L., Galatioto J., Chiu E., Smaldone S., Nelson C.A., Cheng S.H., Wentworth B.M., <strong>Ramirez F<\/strong>. (2015) Dimorphic effects of TGFb signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome. <strong>Arterioscler Thromb Vasc. Biol.<\/strong> 35:911-917.<\/p>\n<p>Zilberberg L., Phoon C.K.L., Robertson I., Dabovic B., <strong>Ramirez F.<\/strong>, Rifkin D.B. (2015) Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome. <strong>Proc. Natl. Acad. Sci. USA<\/strong> 112:14012-14017.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>2016<\/strong><\/p>\n<p>Lee J.J., Galatioto J., Rao S., <strong>Ramirez F.<\/strong>, Costa K.D. (2016) Losartan attenuates degradation of aorta and lung tissue micromechanics in a mouse model of severe Marfan syndrome.\u00a0 <strong>Ann Biomed Eng<\/strong>. 44:2994-3006.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>2018<\/strong><\/p>\n<p>Galatioto J., Caescu C.I., Hansen J. , Cook J., Miramontes I., Iyengar R. and <strong>Ramirez F<\/strong>. (2018) Cell type-specific contributions of the Ang II type 1a receptor to aorta homeostasis and aneurysmal disease. <strong>Arterioscler Thromb Vasc. Biol\u00a0 <\/strong>38:588-591.<\/p>\n<p>Cikach F.S., Koch C.D., Mead T., Galatioto J., WIllared B., Emerton K., Eagleton M., Blackstone E, <strong>Ramirez F<\/strong>, Roselli EE, Apte S. (2018) Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection.\u00a0 <strong>J Clin Invest Insight <\/strong>3(5) e97167.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>2019<\/strong><\/p>\n<p>Hansen J., Galatioto J., Caescu C.I., Arnaud P., Calizo R.C., Spronck B., Murtada S.-I., Borkar R, Weinberg A, Azeloglu EU, Bintanel-Morcillo M, Gallo JM, HumphreyJD, Jondeau G., Boileau C., <strong>Ramirez F.<\/strong>, Iyengar R. (2019) Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms. <strong>JCI Insight<\/strong>\u00a0 4:e127652.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>2021<\/strong><\/p>\n<p>Caescu C.I., Hansen J., Crockett B., Xiao W.,\u00a0 Arnaud P., Spronck B., Weinberg A., Hashimoto T., Murtada S.-I., Borkar R.,\u00a0 Gallo J.M., Jondeau, G.,\u00a0 Catherine Boileau C., Humphrey J.D., He J.C., Iyengar R., Ramirez F. (2021) Inhibition of homeodomain-interacting protein kinase 2 (HIPK2) alleviates thoracic aortic disease in mice with progressively severe Marfan syndrome. <strong>Arterioscler. Thromb Vasc. Biol.<\/strong> Epub adhead of print July 29<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0Search PubMed for articles Selected Publications: 2014 Cook J.R., Carta L., Benard L., Chemaly E.R., Chiu E., Rao S.K., Hampton T.G., Yurchenco P., Costa K.D., Hajjar R.J., Ramirez F. (2014) Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome. J. Clin. Invest. 124:1329-1339. &nbsp; 2015 Cook J.R., Clayton N.P., Carta L., Galatioto J., Chiu [&hellip;]<\/p>\n","protected":false},"author":59,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"open","ping_status":"closed","template":"full-width.php","meta":{"footnotes":""},"class_list":["post-8","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/wp-json\/wp\/v2\/pages\/8","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/wp-json\/wp\/v2\/users\/59"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/wp-json\/wp\/v2\/comments?post=8"}],"version-history":[{"count":4,"href":"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/wp-json\/wp\/v2\/pages\/8\/revisions"}],"predecessor-version":[{"id":110,"href":"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/wp-json\/wp\/v2\/pages\/8\/revisions\/110"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/ramirezlab\/wp-json\/wp\/v2\/media?parent=8"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}