{"id":10,"date":"2016-06-06T18:30:10","date_gmt":"2016-06-06T18:30:10","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/pflegerlab\/?page_id=10"},"modified":"2016-06-06T18:30:31","modified_gmt":"2016-06-06T18:30:31","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/pflegerlab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>Reimels TA, Pfleger CM. <em>Drosophila <\/em>Rabex-5 restricts Notch activity in hematopoietic cells and maintains \u2028hematopoietic homeostasis . <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26567216\"><em>J Cell Sci<\/em> 2015<\/a>; 128: 4512-4525<\/p>\n<p>Fagan JK, Dollar G, Lu Q, Barnett A, Pechuan Jorge J, Schlosser A, Pfleger C, Adler P, Jenny A. Combover\/CG10732, a novel PCP effector for Drosophila wing hair formation.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25207969\"> <em>PLoS One<\/em>. 2014 <\/a>9:e107311.<\/p>\n<p>Ilanges, A., Jahanshahi, M., Balobin, D.M., and C.M. Pfleger. Alcohol Interacts with Genetic Alteration of the Hippo Tumor Suppressor Pathway to Modulate Tissue Growth in <em>Drosophila<\/em>. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24205337\"><em>PLoS One <\/em>2013<\/a>, 8:e78880<em>.<\/em><\/p>\n<p>Liu, H.-Y. and C.M. Pfleger. Mutation in E1, the Ubiquitin Activating Enzyme, Reduces <em>Drosophila <\/em>Lifespan and Results in Motor Impairment. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23382794\"><em>PlosOne <\/em>2013 <\/a>8: e32835.<\/p>\n<p>Wu, K., H. Yan, L. Fang, X. Wang, C. Pfleger, X. Jiang, L. Huang, and Z.Q. Pan. Mono-ubiquitination drives nuclear export of the human Dcn1-like protein hDCNL1. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21813641\">J Biol Chem. 2011<\/a> ; 286: 34060-34070.<\/p>\n<p>Pfleger, C.M., J. Wang, L. Friedman, R. Vittorino, L. Conley, L. Ho, H. Fivecoat, and G.M. Pasinetti. Grape Seed Polyphenolic Extract Improves the Eye Phenotype in a Drosophila Model of Tauopathy. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20871666\"><em>Int J Alzheimer\u2019s Disease <\/em>2010<\/a> pii: 576357<em>.<\/em><\/p>\n<p>Wang, J., C. Pfleger, L. Friedman, R. Vittorino, W. Zhao, X.J. Qian, L. Conley, L. Ho, and G.M. Pasinetti. Potential application of grape derived polyphenols in Huntington\u2019s disease.<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21331299\"><em> Translational Neuroscience <\/em>2010<\/a> 1: 95-100.<\/p>\n<p>Yan, H., M. Jahanshahi, E.A. Horvath, H.-Y. Liu, and C.M. Pfleger. Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in vivo in Drosophila. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20655224\"><em>Current Biology<\/em> 2010<\/a>; 20:1378-1382<em>.<\/em><\/p>\n<p>Yan, H., M.-L. Chin, E.A. Horvath, E.A. Kane, and C.M. Pfleger. Impairment of ubiquitylation by mutation in <em>Drosophila<\/em> E1 promotes both cell-autonomous and non-cell-autonomous Ras-ERK activation <em>in vivo<\/em>. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19366732\"><em>J Cell Science <\/em>2009<\/a>; 122: 1461-1470.<\/p>\n<p>Pfleger, C.M.<sup>1<\/sup>, K.F. Harvey<sup>1<\/sup>, H. Yan, and I.K. Hariharan. Mutation of the Ubiquitin Activating Enzyme Uba1 causes tissue overgrowth in Drosophila. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18820468\"><em>Fly<\/em> 2007<\/a>; 1: 95-105.\u00a0\u00a0\u00a0\u00a0 <em><sup>1<\/sup>These authors contributed equally to this work<\/em>.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Reimels TA, Pfleger CM. Drosophila Rabex-5 restricts Notch activity in hematopoietic cells and maintains \u2028hematopoietic homeostasis . J Cell Sci 2015; 128: 4512-4525 Fagan JK, Dollar G, Lu Q, Barnett A, Pechuan Jorge J, Schlosser A, Pfleger C, Adler P, Jenny A. Combover\/CG10732, a novel PCP effector for Drosophila wing hair formation. PLoS One. 2014 [&hellip;]<\/p>\n","protected":false},"author":146,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-10","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/pflegerlab\/wp-json\/wp\/v2\/pages\/10","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/pflegerlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/pflegerlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pflegerlab\/wp-json\/wp\/v2\/users\/146"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pflegerlab\/wp-json\/wp\/v2\/comments?post=10"}],"version-history":[{"count":2,"href":"https:\/\/labs.icahn.mssm.edu\/pflegerlab\/wp-json\/wp\/v2\/pages\/10\/revisions"}],"predecessor-version":[{"id":12,"href":"https:\/\/labs.icahn.mssm.edu\/pflegerlab\/wp-json\/wp\/v2\/pages\/10\/revisions\/12"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/pflegerlab\/wp-json\/wp\/v2\/media?parent=10"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}