Publications

Reimels TA, Pfleger CM. Drosophila Rabex-5 restricts Notch activity in hematopoietic cells and maintains 
hematopoietic homeostasis . J Cell Sci 2015; 128: 4512-4525

Fagan JK, Dollar G, Lu Q, Barnett A, Pechuan Jorge J, Schlosser A, Pfleger C, Adler P, Jenny A. Combover/CG10732, a novel PCP effector for Drosophila wing hair formation. PLoS One. 2014 9:e107311.

Ilanges, A., Jahanshahi, M., Balobin, D.M., and C.M. Pfleger. Alcohol Interacts with Genetic Alteration of the Hippo Tumor Suppressor Pathway to Modulate Tissue Growth in Drosophila. PLoS One 2013, 8:e78880.

Liu, H.-Y. and C.M. Pfleger. Mutation in E1, the Ubiquitin Activating Enzyme, Reduces Drosophila Lifespan and Results in Motor Impairment. PlosOne 2013 8: e32835.

Wu, K., H. Yan, L. Fang, X. Wang, C. Pfleger, X. Jiang, L. Huang, and Z.Q. Pan. Mono-ubiquitination drives nuclear export of the human Dcn1-like protein hDCNL1. J Biol Chem. 2011 ; 286: 34060-34070.

Pfleger, C.M., J. Wang, L. Friedman, R. Vittorino, L. Conley, L. Ho, H. Fivecoat, and G.M. Pasinetti. Grape Seed Polyphenolic Extract Improves the Eye Phenotype in a Drosophila Model of Tauopathy. Int J Alzheimer’s Disease 2010 pii: 576357.

Wang, J., C. Pfleger, L. Friedman, R. Vittorino, W. Zhao, X.J. Qian, L. Conley, L. Ho, and G.M. Pasinetti. Potential application of grape derived polyphenols in Huntington’s disease. Translational Neuroscience 2010 1: 95-100.

Yan, H., M. Jahanshahi, E.A. Horvath, H.-Y. Liu, and C.M. Pfleger. Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in vivo in Drosophila. Current Biology 2010; 20:1378-1382.

Yan, H., M.-L. Chin, E.A. Horvath, E.A. Kane, and C.M. Pfleger. Impairment of ubiquitylation by mutation in Drosophila E1 promotes both cell-autonomous and non-cell-autonomous Ras-ERK activation in vivo. J Cell Science 2009; 122: 1461-1470.

Pfleger, C.M.1, K.F. Harvey1, H. Yan, and I.K. Hariharan. Mutation of the Ubiquitin Activating Enzyme Uba1 causes tissue overgrowth in Drosophila. Fly 2007; 1: 95-105.     1These authors contributed equally to this work.