{"id":9,"date":"2015-05-29T19:51:48","date_gmt":"2015-05-29T19:51:48","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/peterlab\/?page_id=9"},"modified":"2025-06-25T20:35:56","modified_gmt":"2025-06-25T20:35:56","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/peterlab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<h3>Selected from over 100 peer-reviewed publications<\/h3>\n<hr \/>\n<p>&nbsp;<\/p>\n<p><a name=\"obesitydiabetesandcardiovasculardisease\"><\/a><\/p>\n<h2>Obesity, diabetes, and cardiovascular disease<\/h2>\n<p>Ellis KL, Zhou Y, Rodriguez-Murillo L, Beshansky JR, Ainehsazan E, Selker HP, Huggins GS, Cupples LA, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. Common variants associated with changes in levels of circulating free fatty acids after administration of glucose-insulin-potassium (GIK) therapy in the IMMEDIATE trial. <em>Pharmacogenomics J.<\/em>\u00a0Jan;17(1):76-83. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26644202\">PMID: 26644202<\/a><\/p>\n<p>Udler, M.S., Nadkarni, G.N., Belbin, G., Lotay, V., Wyatt, C., Gottesman, O., Bottinger, E.P., Kenny, E.E. and Peter, I.Effect of Genetic African Ancestry on eGFR and Kidney Disease.<em> J Am Soc Nephrol<\/em> 2015 Jul;26(7):1682-92. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25349204\">PMID:25349204<\/a><\/p>\n<p>Ellis KL, Zhou Y, Beshansky JR, Ainehsazan E, Selker HP, Cupples LA, Huggins GS, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. Genetic modifiers of response to glucose-insulin-potassium (GIK) infusion in acute coronary syndromes and associations with clinical outcomes in the IMMEDIATE trial. <em>Pharmacogenomics J<\/em>. 2015 Mar 17. doi: 10.1038\/tpj.2015.10. [Epub ahead of print] <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=25778467\">PMID:25778467<\/a><\/p>\n<p>Ellis KL, Zhou Y, Beshansky JR, Ainehsazan E, Yang Y, Selker HP, Huggins GS, Cupples LA, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. Genetic variation at glucose and insulin trait loci and response to glucose-insulin-potassium (GIK) therapy: the IMMEDIATE trial. <em>Pharmacogenomics J<\/em>. 2015 Feb; 15(1):55-62. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=25135348\">PMID:25135348<\/a><\/p>\n<p><span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Papandonatos GD, Belalcazar LM, Yang Y, Erar B, Jakicic JM, Unick JL, Balasubramanyam A, Lipkin EW, Delahanty LM, Wagenknecht LE, Wing RR, McCaffery JM, Huggins GS. Genetic Modifiers of Cardiorespiratory Fitness Response to Lifestyle Intervention. <em>Med Sci Sports Exerc<\/em>. 2014 Feb;46(2):302-11. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=23899896\">PMID: 23899896<\/a><\/p>\n<p><span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, McCaffery JM, Kelley-Hedgepeth A, Hakonarson H, Reis S, Wagenknecht LE, Kopin AS, Huggins GS, for the Genetics Subgroup of the Look AHEAD Study. Association of Type 2 Diabetes Susceptibility Loci with One-Year Weight 1 Loss in the Look AHEAD Clinical Trial. <em>Obesity (Silver Spring)<\/em>, 2012 Aug;20(8):1675-82. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=22307069\">PMID: 22307069<\/a><\/p>\n<p>Saxena R, Elbers CC, Guo Y, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, et al. Large-Scale Gene-Centric Meta-Analysis across 39 studies Identifies Type 2 Diabetes Loci. <em>Am J Hum Genet<\/em>, 2012 Mar 9;90(3):410-425. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=22325160\">PMID: 22325160<\/a><\/p>\n<p>Gottesman O, Drill E, Lotay V, Bottinger E, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. Can Genetic Pleiotropy Replicate Common Clinical Constellations of Cardiovascular Disease and Risk? <em>PLoS One<\/em>. 2012;7(9):e46419. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=23029515\">PMID: 23029515<\/a><\/p>\n<p>Polisecki E, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Blauw GJ, Westendorp RG, de Craen AJ, Trompet S, Buckley BM, Murphy MB, Ordovas JM, Schaefer EJ; for the PROSPER Study Group. Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population. <em>Atherosclerosis<\/em>. 2008 Sep;200(1):95-101. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=18262190\">PMID:18262190<\/a><\/p>\n<p><span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Kelley-Hedgepeth A, Fox CS, Cupples LA, Huggins GS, Housman DE, Karas RH, Mendelsohn ME, Levy D, Murabito JM. Variation in Estrogen-Related Genes Associated with Cardiovascular Phenotypes and Circulating Estradiol, Testosterone, and Dehydroepiandrosterone Sulfate Levels. <em>J Clin Endocrinol Metab<\/em> 2008 Jul;93(7):2779-85. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=18445666\">PMID:18445666<\/a><\/p>\n<p><span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Huggins GS, Shearman AM, Pollak A, Schmid CH, Cupples LA, Demissie S, Patten RD, Karas RH, Housman DE, Mendelsohn ME, Vasan RS, Benjamin EJ. Age-related Changes in Echocardiographic Measurements: Association with Variation in the Estrogen Receptor-\u03b1 Gene. <em>Hypertension<\/em>; May;49(5):1000-6, 2007. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=17372038\">PMID:17372038<\/a><\/p>\n<p>Shearman AM, Demissie S, Cupples LA, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Schmid CH, Ordovas JM, Mendelsohn ME and Housman DE. Tobacco smoking, estrogen receptor a gene variation and small low density lipoprotein level. <em>Hum Mol Genet<\/em>, 14(16):2405-2413, 2005. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=16014638\">PMID: 16014638<\/a><\/p>\n<p>Shearman A, Cupples A, Demissie S, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Schmid C, Karas R, Mendelsohn M, Housman D, Levy D. Estrogen Receptor \u03b1 Gene Variation is Associated with Susceptibility to Myocardial Infarction. <em>JAMA<\/em>; 290: 2263-2270, 2003. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=16484614\">PMID:16484614<\/a><\/p>\n<hr \/>\n<p><a name=\"craniosynostosis\"><\/a><\/p>\n<h2>Craniosynostosis<\/h2>\n<p>Sewda A, White SR, Erazo M, Hao K, Garc\u00eda-Fructuoso G, Fern\u00e1ndez-Rodriguez I, Heuz\u00e9 Y, Richtsmeier JT, Romitti PA, Reva B, Jabs EW, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. (2019) Nonsyndromic craniosynostosis: novel coding variants.\u00a0<em>Pediatric Research<\/em> Volume 85, Issue 4, <a href=\"https:\/\/www.nature.com\/pr\/volumes\/85\/issues\/4\">Cover Image<\/a>.<\/p>\n<p>Sewda A, White SR, Erazo M, Hao K, Garc\u00eda-Fructuoso G, Fern\u00e1ndez-Rodriguez I, Heuz\u00e9 Y, Richtsmeier JT, Romitti PA, Reva B, Jabs EW, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. Nonsyndromic craniosynostosis: novel coding variants. <em>Pediatric Research<\/em> (2019). <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30651579\">PMID:30651579<\/a><\/p>\n<p>Ye X, Guilmatre A, Reva B, <strong>Peter I<\/strong>, Heuze Y, Richtsmeier JT, Fox DJ, Goedken RJ, Jabs EW, Romitti PA. Mutation Screening of Candidate Genes in Patients with Nonsyndromic Sagittal Craniosynostosis. <em>Plastic and reconstructive surgery<\/em>. 2016;137(3):952-61. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?cmd=historysearch&amp;querykey=4\">PMID:26910679<\/a><\/p>\n<p>Heuze Y, Holmes G, <strong>Peter I<\/strong>, Richtsmeier JT, Jabs EW. Closing the Gap: Genetic and Genomic Continuum from Syndromic to Nonsyndromic Craniosynostoses. <em>Current genetic medicine reports<\/em>. 2014;2(3):135-45. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26146596\">PMID:26146596<\/a><\/p>\n<p>Justice CM, Yagnik G, Kim Y, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Jabs EW, Erazo M, Ye X, Ainehsazan E, Shi L, Cunningham ML, Kimonis V, Roscioli T, Wall SA, Wilkie AO, Stoler J, Richtsmeier JT, Heuz\u00e9 Y, Sanchez-Lara PA, Buckley MF, Druschel CM, Mills JL, Caggana M, Romitti PA, Kay DM, Senders C, Taub PJ, Klein OD, Boggan J, Zwienenberg-Lee M, Naydenov C, Kim J, Wilson AF, Boyadjiev SA. A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9. <em>Nature Genetics.<\/em> 2012 Dec;44(12):1360-4. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=23160099\">PMID:23160099<\/a><\/p>\n<p>Wang Y, Sun M, Uhlhorn VL, Zhou\u00a0 X, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Martinez-Abadias N, Hill CA, Percival C, Richtsmeier JT, Huso DL, Wang Jabs E. Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2+\/P253R mice. <em>BMC Developmental Biology.<\/em> 2010, 10:22. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=20175913\">PMID:20175913<\/a><a name=\"inflammatoryboweldisease\"><\/a><\/p>\n<hr \/>\n<p><a name=\"inflammatoryboweldisease\"><\/a><\/p>\n<h2>Inflammatory Bowel Disease (IBD)<\/h2>\n<p>Sabino, J., Torres, J., Colombel, J. F., &amp; Peter, I. (2019). Neonatal Life Events and the Risk of Inflammatory Bowel Disease. Gastroenterology, 157(5), 1440\u20131441. <a href=\"https:\/\/doi.org\/10.1053\/j.gastro.2019.04.055\">https:\/\/doi.org\/10.1053\/j.gastro.2019.04.055<\/a><\/p>\n<p>Torres, J., &amp; Peter, I. (2019). Neonatal Exposures and Risk of Inflammatory Bowel Disease: When Does the Clock Start Ticking?. Gastroenterology, 157(2), 577\u2013578. <a href=\"https:\/\/doi.org\/10.1053\/j.gastro.2019.06.010\">https:\/\/doi.org\/10.1053\/j.gastro.2019.06.010<\/a><\/p>\n<p>Hu J, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. Evidence of Expression Variation and Allelic Imbalance in Crohn&#8217;s Disease Susceptibility Genes NOD2 and ATG16L1 in Human Dendritic Cells. <em>Gene<\/em>. 2013 Sep 25;527(2):496-502. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=23850724\">PMID: 23850724<\/a><\/p>\n<p>Zhang W, Hui KY, Gusev A, Warner N, Ng SM, Ferguson J, Choi M, Burberry A, Abraham C, Mayer L, Desnick RJ, Cardinale CJ, Hakonarson H, Waterman M, Chowers Y, Karban A, Brant SR, Silverberg MS, Gregersen PK, Katz S, Lifton RP, Zhao H, Nu\u00f1ez G, Pe&#8217;er I, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Cho JH. Extended haplotype association study in Crohn&#8217;s disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-\u03baB pathway gene, HEATR3.<em>Genes Immun<\/em>. 2013 Jul-Aug;14(5):310-6. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=23615072\">PMID: 23615072<\/a><\/p>\n<p>Kenny EE, Pe\u2019er I, Karban A, Ozelius L, Mitchell AA, Ng SM, Erazo M, Ostrer H, Abraham C, Abreu MT, Atzmon G, Barzilai N, Brant S, Burns ER, Chowers Y, Clark LN, Darvasi A, Doheny D, Duerr RH, Eliakim R, Giladi N, Gregersen PK, Hakonarson H, Jones MR, McGovern DPB, Mulle J, Orr-Urtreger A, Proctor DD, Pulver A, Rotter JI, Silverberg MS, Ullman T, Warren ST, Waterman M, Zhang W, Bergman A, Mayer L, Katz S, Desnick RJ, Cho JH, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. A Genome-Wide Scan of Ashkenazi Jewish Crohn\u2019s Disease Suggests Novel Susceptibility Loci. <em>PLoS Genet<\/em>, 2012 Mar;8(3):e1002559. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=22412388\">PMID:22412388<\/a><\/p>\n<p><span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Michell AA, Ozelius L, Erazo M, Hu J, Doehny D, Abrue MT, Present DH, Ullman T, Korelitz B, Mayer L, Desnick RJ and The New York Crohn&#8217;s Disease Working Group. Evaluation of 22 Genetic Variants with Crohn&#8217;s Disease Risk in the Ashkenazi Jewish Population: a Case-Control Study. <em>BMC Medical Genetics<\/em> 2011 May 6;12(1):63. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=21548950\">PMID:21548950<\/a><\/p>\n<hr \/>\n<p><a name=\"ibd-parkinsonsdisease\"><\/a><\/p>\n<h2 id=\"ibdparkinsonsdisease\">IBD &#8211; Parkinson&#8217;s Disease<\/h2>\n<p>Chai Z, Ouyang Y, Debebe A, et al. Intestinal biomarkers, microbiota composition, and genetic predisposition to inflammatory bowel disease as predictors of Parkinson\u2019s disease manifestation. Journal of Parkinson\u2019s Disease. 2025;0(0).\u00a0<a href=\"https:\/\/doi.org\/10.1177\/1877718X251328567\">https:\/\/doi.org\/10.1177\/1877718X251328567<\/a><\/p>\n<p>Taymans, JM., Fell, M., Greenamyre, T. et al. Perspective on the current state of the LRRK2 field. npj Parkinsons Dis. 9, 104 (2023).\u00a0<a href=\"https:\/\/doi.org\/10.1038\/s41531-023-00544-7\">https:\/\/doi.org\/10.1038\/s41531-023-00544-7<\/a><\/p>\n<p>Peter, I., &amp; Strober, W. (2023). Immunological Features of LRRK2 Function and Its Role in the Gut-Brain Axis Governing Parkinson\u2019s Disease. Journal of Parkinson\u2019s disease, 13(3), 279\u2013296.\u00a0<a href=\"https:\/\/doi.org\/10.3233\/JPD-230021\">https:\/\/doi.org\/10.3233\/JPD-230021<\/a><\/p>\n<p>Peter, I., Dubinsky, M., Xuan, S., Chen, N., &amp; Wang, A. (2022). Letter to the Editor: Re-Revisiting the Association Between Inflammatory Bowel Disease and Parkinson\u2019s Disease. Inflammatory bowel diseases, 28(6), e72.\u00a0<a href=\"https:\/\/doi.org\/10.1093\/ibd\/izac049\">https:\/\/doi.org\/10.1093\/ibd\/izac049<\/a><\/p>\n<p>Weimers, P., Halfvarson, J., Sachs, M. C., Saunders-Pullman, R., Ludvigsson, J. F., Peter, I., Burisch, J., &amp; Ol\u00e9n, O. (2019). Inflammatory Bowel Disease and Parkinson\u2019s Disease: A Nationwide Swedish Cohort Study. Inflammatory bowel diseases, 25(1), 111\u2013123.\u00a0<a href=\"https:\/\/doi.org\/10.1093\/ibd\/izy190\">https:\/\/doi.org\/10.1093\/ibd\/izy190<\/a><\/p>\n<p>Weimers, P., Halfvarson, J., Sachs, M. C., Ludvigsson, J. F., Peter, I., Ol\u00e9n, O., &amp; Burisch, J. (2019). Association between inflammatory bowel disease and Parkinson\u2019s disease: seek and you shall find?. Gut, 68(1), 175\u2013176.\u00a0<a href=\"https:\/\/doi.org\/10.1136\/gutjnl-2018-316937\">https:\/\/doi.org\/10.1136\/gutjnl-2018-316937<\/a><\/p>\n<p>Takagawa, T., Kitani, A., Fuss, I., Levine, B., Brant, S. R., Peter, I., Tajima, M., Nakamura, S., &amp; Strober, W. (2018). An increase in LRRK2 suppresses autophagy and enhances Dectin-1-induced immunity in a mouse model of colitis. Science translational medicine, 10(444), eaan8162.\u00a0<a href=\"https:\/\/doi.org\/10.1126\/scitranslmed.aan8162\">https:\/\/doi.org\/10.1126\/scitranslmed.aan8162<\/a><\/p>\n<p>Peter, I., Dubinsky, M., Bressman, S., Park, A., Lu, C., Chen, N., &amp; Wang, A. (2018). Anti-Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease. JAMA neurology, 75(8), 939\u2013946.\u00a0<a href=\"https:\/\/doi.org\/10.1001\/jamaneurol.2018.0605\">https:\/\/doi.org\/10.1001\/jamaneurol.2018.0605<\/a><\/p>\n<p>Hui, K. Y., Fernandez-Hernandez, H., Hu, J., Schaffner, A., Pankratz, N., Hsu, N. Y., Chuang, L. S., Carmi, S., Villaverde, N., Li, X., Rivas, M., Levine, A. P., Bao, X., Labrias, P. R., Haritunians, T., Ruane, D., Gettler, K., Chen, E., Li, D., Schiff, E. R., \u2026 Peter, I. (2018). Functional variants in the LRRK2 gene confer shared effects on risk for Crohn\u2019s disease and Parkinson\u2019s disease. Science translational medicine, 10(423), eaai7795.\u00a0<a href=\"https:\/\/doi.org\/10.1126\/scitranslmed.aai7795\">https:\/\/doi.org\/10.1126\/scitranslmed.aai7795<\/a><\/p>\n<hr \/>\n<p><a name=\"meconiumstudy\"><\/a><\/p>\n<h2 id=\"meconiumstudy\">MECONIUM Study<\/h2>\n<h2><a href=\"https:\/\/labs.icahn.mssm.edu\/peterlab\/the-meconium-study\/#MECpublications\">Link to publications<\/a><\/h2>\n<hr \/>\n<p><a name=\"microbiome\"><\/a><\/p>\n<h2>Microbiome<\/h2>\n<p>Torres, J., Hu, J., Seki, A., Eisele, C., Nair, N., Huang, R., Tarassishin, L., Jharap, B., Cote-Daigneault, J., Mao, Q., Mogno, I., Britton, G. J., Uzzan, M., Chen, C. L., Kornbluth, A., George, J., Legnani, P., Maser, E., Loudon, H., Stone, J., \u2026 Peter, I. (2020). Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice. Gut, 69(1), 42\u201351. <a href=\"https:\/\/doi.org\/10.1136\/gutjnl-2018-317855\">https:\/\/doi.org\/10.1136\/gutjnl-2018-317855<\/a><\/p>\n<p>Hu, J., Ly, J., Zhang, W., Huang, Y., Glover, V., Peter, I., Hurd, Y. L., &amp; Nomura, Y. (2019). Microbiota of newborn meconium is associated with maternal anxiety experienced during pregnancy. Developmental psychobiology, 61(5), 640\u2013649. https:\/\/doi.org\/10.1002\/dev.21837<\/p>\n<p>Walker, R. W., Clemente, J. C., Peter, I., &amp; Loos, R. J. F. (2017). The prenatal gut microbiome: are we colonized with bacteria in utero?. Pediatric obesity, 12 Suppl 1(Suppl 1), 3\u201317. <a href=\"https:\/\/doi.org\/10.1111\/ijpo.12217\">https:\/\/doi.org\/10.1111\/ijpo.12217<\/a><\/p>\n<p>Palm NW, de Zoete MR, Cullen TW, Barry NA, Stefanowski J, Hao L, Degnan PH, Hu J, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Zhang W, Ruggiero E, Cho JH, Goodman AL, Flavell RA. Immunoglobulin a coating identifies colitogenic bacteria in inflammatory bowel disease. <em>Cell<\/em>. 2014 Aug 28;158(5):1000-10. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=25171403\">PMID:25171403<\/a><\/p>\n<p>Hu J, Nomura Y, Bashir A, Fernandez-Hernandez H, Itzkowitz S, Pei Z, Stone J, Loudon H, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. Diversified microbiota of meconium is affected by maternal diabetes status. <em>PLoS One<\/em>. 2013 Nov 6;8(11):e78257. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=24223144\">PMID: 24223144<\/a><\/p>\n<hr \/>\n<p><a name=\"geneticsofashkenazijewishpopulation\"><\/a><\/p>\n<h2>Genetics of Ashkenazi Jewish Population in Health and Disease<\/h2>\n<p>Carmi S, Hui KY, Kochav E, Liu X, Xue J, Grady F, Guha S, Upadhyay K, Ben-Avraham D, Mukherjee S, Bowen BM, Thomas T, Vijai J, Cruts M, Froyen G, Lambrechts D, Plaisance S, Van Broeckhoven C, Van Damme P, Van Marck H, Barzilai N, Darvasi A, Offit K, Bressman S, Ozelius LJ, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Cho JH, Ostrer H, Atzmon G, Clark LN, Lencz T, Pe&#8217;er I. Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins. <em>Nat Commun<\/em>. 2014 Sep 9;5:4835. doi: 10.1038\/ncomms5835. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=25203624\">PMID:25203624<\/a><\/p>\n<p>Vacic V, Ozelius LJ, Clark LN, Bar-Shira A, Gana-Weisz M, Gurevich T, Gusev A, Kedmi M, Kenny EE, Liu X, Mejia-Santana H, Mirelman A, Raymond D, Saunders-Pullman R, Desnick RJ, Atzmon G, Burns ER, Ostrer H, Hakonarson H, Bergman A, Barzilai N, Darvasi A, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Guha S, Lencz T, Giladi N, Marder K, Pe&#8217;er I, Bressman SB, Orr-Urtreger A. Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes. <em>Hum Mol Genet<\/em>. 2014 Sep 1;23(17):4693-702 <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=24842889\">PMID:24842889<\/a><\/p>\n<p>Kenny EE, Pe\u2019er I, Karban A, Ozelius L, Mitchell AA, Ng SM, Erazo M, Ostrer H, Abraham C, Abreu MT, Atzmon G, Barzilai N, Brant S, Burns ER, Chowers Y, Clark LN, Darvasi A, Doheny D, Duerr RH, Eliakim R, Giladi N, Gregersen PK, Hakonarson H, Jones MR, McGovern DPB, Mulle J, Orr-Urtreger A, Proctor DD, Pulver A, Rotter JI, Silverberg MS, Ullman T, Warren ST, Waterman M, Zhang W, Bergman A, Mayer L, Katz S, Desnick RJ, Cho JH, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>. A Genome-Wide Scan of Ashkenazi Jewish Crohn\u2019s Disease Suggests Novel Susceptibility Loci. <em>PLoS Genet<\/em>, 2012 Mar;8(3):e1002559. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=22412388\">PMID:22412388<\/a><\/p>\n<hr \/>\n<p><a name=\"othertopics\"><\/a><\/p>\n<h2>Other topics<\/h2>\n<p>Hu, J., Iragavarapu, S., Nadkarni, G. N., Huang, R., Erazo, M., Bao, X., Verghese, D., Coca, S., Ahmed, M. K., &amp; Peter, I. (2017). Location-Specific Oral Microbiome Possesses Features Associated With CKD. Kidney international reports, 3(1), 193\u2013204. https:\/\/doi.org\/10.1016\/j.ekir.2017.08.018<\/p>\n<p><span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Huggins GS, Ordovas JM, Haan M, Seddon JM. Evaluation of New and Established AMD Susceptibility Genes in the Women\u2019s Health Initiative Sight Exam (WHI-SE) Study. <em>Am J Ophthalmol<\/em>, 2011 Dec;152(6):1005-1013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=21906714\">PMID:21906714<\/a><\/p>\n<p>Z\u00fcchner S, Dallman J, Wen R, Beecham G, Naj A, Farooq A, Kohli MA, Whitehead PL, Hulme W, Konidari I, Edwards YJK, Buxbaum JD, Cai, G, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Seo D, Haines JL, Blanton S, Young J, Alfonso E, Vance JM, Lam BL, Pericak-Vance MA. Whole-exome sequencing links a variant in DHDDS to retinitis pigmentosa. <em>Am J Hum Genet<\/em> 88, 1\u20136, Feb. 11, 2011. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=21295283\">PMID:21295283<\/a><\/p>\n<p><span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Tighiouart H, Lapaire O, Johnson KL, Bianchi DW, Terrin N. Cell free DNA fragmentation patterns in amniotic fluid identify genetic abnormalities and changes due to storage. <em>Diag Mol Pathol<\/em> 2008 Sep;17(3):185-90. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=18382362\">PMID:18382362<\/a><\/p>\n<p>Urato AC, <span style=\"text-decoration: underline\"><strong>Peter I<\/strong><\/span>, Canick J, Lambert-Messerlian G, Pulkkinen A, Knight G, Jeong YJ, Johnson KL, Bianchi DW. Smoking in pregnancy is associated with increased total maternal serum cell-free DNA levels. <em>Prenat Diagn<\/em>; Mar;28(3):186-90, 2008. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=18260159\">PMID:18260159<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Selected from over 100 peer-reviewed publications &nbsp; Obesity, diabetes, and cardiovascular disease Ellis KL, Zhou Y, Rodriguez-Murillo L, Beshansky JR, Ainehsazan E, Selker HP, Huggins GS, Cupples LA, Peter I. Common variants associated with changes in levels of circulating free fatty acids after administration of glucose-insulin-potassium (GIK) therapy in the IMMEDIATE trial. Pharmacogenomics J.\u00a0Jan;17(1):76-83. 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