{"id":520,"date":"2026-09-17T19:03:14","date_gmt":"2026-09-17T19:03:14","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/?p=520"},"modified":"2026-09-17T19:05:05","modified_gmt":"2026-09-17T19:05:05","slug":"study-identifies-candidate-treatment-targets-for-high-grade-glioma-in-children-and-young-adults","status":"publish","type":"post","link":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/study-identifies-candidate-treatment-targets-for-high-grade-glioma-in-children-and-young-adults\/","title":{"rendered":"Study Identifies Candidate Treatment Targets for High-Grade Glioma in Children and Young Adults"},"content":{"rendered":"<p><img decoding=\"async\" class=\"aligncenter size-medium wp-image-522\" style=\"width: 650px !important;height: auto !important\" src=\"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-content\/uploads\/sites\/226\/2026\/09\/image-23-1.png\" alt=\"\" \/><\/p>\n<div style=\"width: 646px;\" class=\"wp-video\"><!--[if lt IE 9]><script>document.createElement('video');<\/script><![endif]-->\n<video class=\"wp-video-shortcode\" id=\"video-520-1\" width=\"646\" height=\"363\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-content\/uploads\/sites\/226\/2026\/09\/HGG_Proteogenomics_Digital_Display-1.mp4?_=1\" \/><a href=\"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-content\/uploads\/sites\/226\/2026\/09\/HGG_Proteogenomics_Digital_Display-1.mp4\">https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-content\/uploads\/sites\/226\/2026\/09\/HGG_Proteogenomics_Digital_Display-1.mp4<\/a><\/video><\/div>\n<p>&nbsp;<\/p>\n<p><em>Our study finds tumor biology shifts with age and differs by sex<\/em><\/p>\n<p>Together with collaborators, we identified candidate treatment targets and potential prognostic markers for high-grade glioma, an aggressive brain cancer, in children, adolescents, and young adults.<\/p>\n<p>The study found that high-grade glioma varies by developmental stage and sex, showing distinct tumor biology and outcomes across patient groups. Using this information to guide clinical trial design and develop new therapies could advance more precise treatment strategies. The paper describing above findings, <em><a href=\"https:\/\/www.cell.com\/cell-reports-medicine\/fulltext\/S2666-3791(26)00441-6\">Tignor et al <\/a><\/em>, was published online September 17 in <span style=\"color: #3366ff\"><em>Cell Reports Medicine<\/em><\/span>.<\/p>\n<p>Please see below posts for details:<\/p>\n<p><a href=\"https:\/\/www.mountsinai.org\/about\/newsroom\/2026\/study-identifies-candidate-treatment-targets-for-high-grade-glioma-in-children-and-young-adults\">Mount Sinai Newsroom<\/a><\/p>\n<p><a href=\"https:\/\/www.newswise.com\/articles\/study-identifies-candidate-treatment-targets-for-high-grade-glioma-in-children-and-young-adults\">Newswise News<\/a><\/p>\n<p><a href=\"https:\/\/hope.cptac-data-view.org\/\">Data Visualization on ProTrack: Ped\/AYA HGG<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Our study finds tumor biology shifts with age and differs by sex Together with collaborators, we identified candidate treatment targets and potential prognostic markers for high-grade glioma, an aggressive brain cancer, in children, adolescents, and young adults. The study found that high-grade glioma varies by developmental stage and sex, showing distinct tumor biology and [&hellip;]<\/p>\n","protected":false},"author":233,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-520","post","type-post","status-publish","format-standard","hentry","category-investigator"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/posts\/520","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/users\/233"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/comments?post=520"}],"version-history":[{"count":10,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/posts\/520\/revisions"}],"predecessor-version":[{"id":536,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/posts\/520\/revisions\/536"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/media?parent=520"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/categories?post=520"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/tags?post=520"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}