{"id":184,"date":"2017-06-13T02:03:04","date_gmt":"2017-06-13T02:03:04","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/?page_id=184"},"modified":"2021-11-10T20:03:15","modified_gmt":"2021-11-10T20:03:15","slug":"project","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/project\/","title":{"rendered":"Project"},"content":{"rendered":"

CPTAC-PGDAC at Mount Sinai<\/strong><\/h3>\n

The aims of our PGDAC are to: 1) derive biological and clinically relevant information from the CPTAC proteogenomic(PG) data, 2)\u00a0develop new computational\/software\/web tools for analyzing CPTAC data and for visualizing\/interpreting our analysis results, and 3)\u00a0identify protein biomarkers and drug targets for further investigation by targeted proteomics assays.<\/p>\n

CPTAC Flagship Papers<\/strong><\/p>\n

We have led and\/or contributed to the following research on cancer proteogenomics:<\/p>\n

A proteogenomic portrait of lung squamous cell carcinoma
\n<\/a>
\nProteogenomic and metabolomic characterization of human glioblastoma
\n<\/a>
\nProteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
\n<\/a>
\nIntegrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer
\n<\/a>
\nProteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma
\n<\/a>
\nProteogenomic Characterization of Endometrial Carcinoma
\n<\/a>
\nIntegrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma
\n<\/a>
\nIntegrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
\n<\/a><\/p>\n

\n

A proteogenomic portrait of lung squamous cell carcinoma
\n<\/strong>Satpathy et al. Cell<\/em>. Aug 2021. PMID: 34358469<\/p>\n

<\/a> Read the full text at Cell<\/a><\/p>\n

\n

Proteogenomic and metabolomic characterization of human glioblastoma
\n<\/strong>Wang et al. Cancer Cell<\/em>. Apr 2021. PMID: 33577785<\/p>\n

<\/a> Read the full text at Cancer Cell<\/a><\/p>\n

\n

Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
\n<\/strong>Huang et al. Cancer Cell<\/em>. Mar 2021. PMID: 33417831<\/p>\n

<\/a> Read the full text at Cancer Cell<\/a><\/p>\n

\n

Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer
\n<\/strong>Petralia et al. Cell<\/em>. Dec 2020. PMID: 33242424<\/p>\n

<\/a><\/p>\n

Read the full text at Cell<\/a><\/p>\n

You can explore the pediatric brain tumor data with interactive heatmap with our ProTrack web tool at http:\/\/pbt.cptac-data-view.org\/<\/a><\/p>\n

Related reading:
\nProteogenomic analysis provides new insights into pediatric brain tumors<\/a><\/p>\n

\n

Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma
\n<\/strong>Gillette et al. Cell<\/em>. July 2020. PMID: 32649874<\/p>\n

<\/a> Read the full text at Cell<\/a><\/p>\n

\n

Proteogenomic Characterization of Endometrial Carcinoma
\n<\/strong>Dou et al. Cell<\/em>. Feb 2020. PMID: 32059776<\/p>\n

<\/a> Read the full text at Cell<\/a><\/p>\n

\n

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma
\n<\/strong>Clark et al. Cell<\/em>. Oct 2019. PMID: 31675502<\/p>\n

<\/a><\/p>\n

Read the full text at Cell<\/a><\/p>\n

You can explore the ccRCC cohort data with interactive heatmap with our ProTrack web tool at http:\/\/ccrcc.cptac-data-view.org\/<\/a><\/p>\n

\n

Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
\n<\/strong>Gao et al. Cell<\/em>. Oct 2019. PMID: 31585088<\/p>\n

<\/a><\/p>\n

Read the full text at Cell<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

CPTAC-PGDAC at Mount Sinai The aims of our PGDAC are to: 1) derive biological and clinically relevant information from the CPTAC proteogenomic(PG) data, 2)\u00a0develop new computational\/software\/web tools for analyzing CPTAC data and for visualizing\/interpreting our analysis results, and 3)\u00a0identify protein biomarkers and drug targets for further investigation by targeted proteomics assays. CPTAC Flagship Papers We […]<\/p>\n","protected":false},"author":146,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-184","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/pages\/184","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/users\/146"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/comments?post=184"}],"version-history":[{"count":18,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/pages\/184\/revisions"}],"predecessor-version":[{"id":446,"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/pages\/184\/revisions\/446"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/pei-wang-lab\/wp-json\/wp\/v2\/media?parent=184"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}