{"id":25,"date":"2021-08-30T21:00:55","date_gmt":"2021-08-30T21:00:55","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/pawlicalab2\/?page_id=25"},"modified":"2026-07-08T21:45:43","modified_gmt":"2026-07-08T21:45:43","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/publications\/","title":{"rendered":"PUBLICATIONS"},"content":{"rendered":"
\n

\nPhan N, Pawlica P<\/strong>. Viral non-coding RNAs hijack host Pumilio proteins to regulate host transcripts. bioRxiv<\/em>. 2025. https:\/\/doi.org\/10.1101\/2025.11.27.691032<\/a>\n<\/p>\n

\nPhan N*, Zaytseva Y*, Lin CC, Mishra M, Sun W, Pawlica P<\/strong>. PUM2 binds SARS-CoV-2 RNA and PUM1 mildly reduces viral RNA levels, but neither protein affects progeny virus production. J Gen Virol<\/em>. 2025;106(9). PMID: 40956600<\/a>. (*contributed equally)\n<\/p>\n

\nPawlica P*<\/strong>, Yario TA, White S, Wang J, Moss WN, Hui P, Vinetz JM, Steitz JA. SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes. Proc Natl Acad Sci U S A<\/em>. 2021;118. PMID: 34903581<\/a>. (*co-corresponding author)\n<\/p>\n

\nPawlica P<\/strong>, Sheu-Gruttadauria J, MacRae IJ, Steitz JA. How complementary targets expose the microRNA 3\u2032 end for tailing and trimming during target-directed microRNA degradation. Cold Spring Harb Symp Quant Biol<\/em>. 2020. PMID: 32019864<\/a>.\n<\/p>\n

\nSheu-Gruttadauria J*, Pawlica P*<\/strong>, Klum SM, Wang S, Yario TA, Schirle-Oakdale NT, Steitz JA, MacRae IJ. Structural basis for target-directed microRNA degradation. Mol Cell<\/em>. 2019;75(6):1243-1255. PMID: 31353209<\/a>. (*contributed equally)\n<\/p>\n

\nWithers JB, Mondol V, Pawlica P<\/strong>, Rosa-Mercado NA, Tycowski KT, Ghasempur S, Torabi SF, Steitz JA. Idiosyncrasies of viral noncoding RNAs provide insights into host cell biology. Annu Rev Virol<\/em>. 2019;6(1):297-317. PMID: 31039329<\/a>.\n<\/p>\n

\nPawlica P<\/strong>, Moss WN, Steitz JA. Host miRNA degradation by Herpesvirus saimiri small nuclear RNA requires an unstructured interacting region. RNA<\/em>. 2016;22(8):1181-1189. PMID: 27335146<\/a>.\n<\/p>\n

\nPawlica P<\/strong>, Dufour C, Berthoux L. Inhibition of microtubules and dynein rescues HIV-1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion. J Gen Virol<\/em>. 2015;96(Pt 4):874-886. PMID: 25502651<\/a>.\n<\/p>\n

\nPawlica P<\/strong>, Le Sage V, Poccardi N, Tremblay MJ, Mouland AJ, Berthoux L. Functional evidence for the involvement of microtubules and dynein motor complexes in TRIM5\u03b1-mediated restriction of retroviruses. J Virol<\/em>. 2014;88(10):5661-5676. PMID: 24600008<\/a>.\n<\/p>\n

\nPawlica P<\/strong>, Berthoux L. Cytoplasmic dynein promotes HIV-1 uncoating. Viruses<\/em>. 2014;6(11):4195-4211. PMID: 25375884<\/a>.\n<\/p>\n

\nVeillette M, Bichel K, Pawlica P<\/strong>, Freund SM, Plourde MB, Pham QT, Reyes-Moreno C, James LC, Berthoux L. The V86M mutation in HIV-1 capsid confers resistance to TRIM5\u03b1 by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import. Retrovirology<\/em>. 2013;10:25. PMID: 23448277<\/a>.\n<\/p>\n

\nPham QT, Veillette M, Brandariz-Nu\u00f1ez A, Pawlica P<\/strong>, Thibert-Lefebvre C, Chandonnet N, Diaz-Griffero F, Berthoux L. A novel amino acid determinant of HIV-1 restriction in the TRIM5\u03b1 variable 1 region isolated in a random mutagenic screen. Virus Res<\/em>. 2013;173(2):306-314. PMID: 23357295<\/a>.\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Phan N, Pawlica P. Viral non-coding RNAs hijack host Pumilio proteins to regulate host transcripts. bioRxiv. 2025. https:\/\/doi.org\/10.1101\/2025.11.27.691032 Phan N*, Zaytseva Y*, Lin CC, Mishra M, Sun W, Pawlica P. PUM2 binds SARS-CoV-2 RNA and PUM1 mildly reduces viral RNA levels, but neither protein affects progeny virus production. J Gen Virol. 2025;106(9). PMID: 40956600. (*contributed […]<\/p>\n","protected":false},"author":493,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"off","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-25","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/pages\/25","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/users\/493"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/comments?post=25"}],"version-history":[{"count":31,"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/pages\/25\/revisions"}],"predecessor-version":[{"id":802,"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/pages\/25\/revisions\/802"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/media?parent=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}