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<\/span><\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Phan N, Pawlica P. Viral non-coding RNAs hijack host Pumilio proteins to regulate host transcripts. bioRxiv. 2025. https:\/\/doi.org\/10.1101\/2025.11.27.691032 Phan N*, Zaytseva Y*, Lin CC, Mishra M, Sun W, Pawlica P. PUM2 binds SARS-CoV-2 RNA and PUM1 mildly reduces viral RNA levels, but neither protein affects progeny virus production. J Gen Virol. 2025;106(9). PMID: 40956600 (* […]<\/p>\n","protected":false},"author":493,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":" 2021<\/strong><\/p> Pawlica P<\/strong>, Yario T, White S, Wang J, Moss WN, Hui P, Vinetz JM, Steitz JA. SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes. bioRxiv. 2021:2021.09.08.459464. doi: 10.1101\/2021.09.08.459464. [preprint; not yet peer-reviewed]<\/p> \u00a0<\/p> 2020<\/strong><\/p> Pawlica P<\/strong>, Sheu-Gruttadauria J, MacRae I J, Steitz J A, How complementary targets expose the microRNA 3' end for tailing and trimming during target-directed microRNA degradation, Cold Spring Harb Symp Quant Biol, 2020, Feb 4;039321. PMID: 32019864<\/p> \u00a0<\/p> 2019<\/strong><\/p> Sheu-Gruttadauria J*, Pawlica P<\/strong>* (* contributed equally), Klum SM, Wang S, Yario TA, Schirle-Oakdale NT, Steitz JA, MacRae IJ, 2019, Structural basis for target-directed microRNA degradation, Molecular Cell. 2019 Sep 19;75(6):1243-1255. PMCID: PMC6754277<\/p> Withers JB, Mondol V, Pawlica P<\/strong>, Rosa-Mercado NA, Tycowski KT, Ghasempur S, Torabi SF, and Steitz JA, 2019, Idiosyncrasies of viral noncoding RNAs provide insights into host cell biology. Annual Review of Virology. 019 Sep 29;6(1):297-317, PMCID: PMC6768742<\/p> Pawlica P<\/strong>, Moss W N, Steitz J A, 2016, Host miRNA degradation by Herpesvirus saimiri small nuclear RNA requires an unstructured interacting region, RNA, 2016, 22(8):1181-9, PMCID: PMC4931111<\/p> \u00a0<\/p> 2015<\/strong><\/p> Pawlica P<\/strong>, Dufour C, Berthoux L, 2015, Inhibition of microtubules and dynein rescues HIV-1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion, Journal of General Virology, Apr;96(Pt 4):874-86, PMID: 25502651<\/p> \u00a0<\/p> 2014<\/strong><\/p> Pawlica P<\/strong>, Le Sage V, Poccardi N, Tremblay MJ, Mouland AJ, Berthoux L, 2014, Functional evidence for the involvement of microtubules and dynein motor complexes in TRIM5\u03b1-mediated restriction of retroviruses, Journal of Virology, 88(10):5661-76, PMCID: PMC4019117<\/p> Pawlica P<\/strong>, Berthoux L, 2014, Cytoplasmic dynein promotes HIV-1 uncoating, Viruses, 6(11), 4195-4211, PMCID: PMC4246216<\/p> \u00a0<\/p> 2013<\/strong><\/p> Veillette M, Bichel K, Pawlica P<\/strong>, Freund SM, Plourde MB, Pham QT, Reyes-Moreno C, James LC, Berthoux L, 2013, The V86M mutation in HIV-1 capsid confers resistance to TRIM5\u03b1 by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import, Retrovirology, 10:25, PMCID: PMC3598646<\/p> Pham QT, Veillette M, Brandariz-Nu\u00f1ez A, Pawlica P<\/strong>, Thibert-Lefebvre C, Chandonnet N, Diaz-Griffero F, Berthoux L, 2013, A novel aminoacid determinant of HIV-1 restriction in the TRIM5\u03b1 variable 1 region isolated in a random mutagenic screen, Virus Research, 173(2):306-14, PMCID: PMC4317569<\/p>","_et_gb_content_width":"","footnotes":""},"class_list":["post-25","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/pages\/25","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/users\/493"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/comments?post=25"}],"version-history":[{"count":28,"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/pages\/25\/revisions"}],"predecessor-version":[{"id":738,"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/pages\/25\/revisions\/738"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/pawlicalab\/wp-json\/wp\/v2\/media?parent=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}