
{"id":2494,"date":"2022-12-20T11:44:55","date_gmt":"2022-12-20T16:44:55","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/design\/?page_id=2494"},"modified":"2023-06-08T20:36:21","modified_gmt":"2023-06-09T00:36:21","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/papapetroulab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Section 28 &#8211; Blog Style Publications&#8221; module_class=&#8221;section28_blog_style_publications&#8221; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#FFFFFF&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/papapetroulab2\/wp-content\/uploads\/sites\/491\/2022\/10\/Background-1.png&#8221; parallax=&#8221;on&#8221; parallax_method=&#8221;off&#8221; min_height=&#8221;1075.6px&#8221; custom_padding=&#8221;13px||||false|false&#8221; global_module=&#8221;2511&#8243; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221;][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;]<\/p>\n<h1 style=\"text-align: center\">Selected Publications<\/h1>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221;]<\/p>\n<p>Kotini AG, Carcamo S, Cruz-Rodriguez N, Olszewska M, Wang T, Demircioglu D, Chang, C-J, Bernard E, Chao MP, Majeati R, Luo H, Kharas MG, Hasson D, Papapetrou EP<strong>*<\/strong>.<br \/> <strong>Patient-derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia.<\/strong><br \/> <em>Blood Cancer Discov<\/em>. In Press<br \/><a href=\"https:\/\/aacrjournals.org\/bloodcancerdiscov\/article\/doi\/10.1158\/2643-3230.BCD-22-0167\/725897\/Patient-Derived-iPSCs-Faithfully-Represent-the\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"font-size: 16px\"><b>Read more<\/b><\/a><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221;]<\/p>\n<p>Wheeler EC<sup>$<\/sup>, Vora S<sup>$<\/sup>, Mayer D, Kotini AG, Olszewska M, Park SS, Guccione E, Teruya-Feldstein J, Silverman L, Sunahara RK, Yeo GW*, Papapetrou EP*.<br \/><strong>Integrative RNA-omics discovers<span>\u00a0<\/span><em>GNAS<\/em><span>\u00a0<\/span>alternative splicing as a phenotypic driver of splicing factor-mutant neoplasms.<\/strong><br \/><em>Cancer Discovery<span>\u00a0<\/span><\/em>2022; 12:836-855.<br \/><a href=\"https:\/\/aacrjournals.org\/cancerdiscovery\/article\/12\/3\/836\/681884\/Integrative-RNA-omics-Discovers-GNAS-Alternative\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"font-size: 16px\"><b>Read more<\/b><\/a><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221;]<\/p>\n<p>Wang T<sup>$<\/sup>, Pine AR<sup>$<\/sup>, Kotini AG, Yuan H, Zamparo L, Starczynowski DT, Leslie C<strong>*<\/strong>, Papapetrou EP<strong>*<\/strong>.<br \/><strong>Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets.<\/strong><em><br \/>Cell Stem Cell<span>\u00a0<\/span><\/em>2021; 28: 1074-1089.<br \/><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1934590921000114?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"font-size: 16px\"><b>Read more<\/b><\/a><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221;]<\/p>\n<p>Papapetrou EP.\u00a0<span><br \/><\/span><strong>Modeling Leukemia with Human Induced Pluripotent Stem Cells.\u00a0<\/strong><br \/><em>Cold Spring Harb Perspect Med<\/em>.<span>\u00a0<\/span>2019 Dec 2;9(12):a034868. doi: 10.1101\/cshperspect.a034868.<br \/><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31451537\/\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"font-size: 16px\"><b>Read more<\/b><\/a><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221;]<\/p>\n<p>Kotini AG, Chang CJ, Chow A, Yuan H, Ho TC, Wang T, Vora S, Solovyov A, Husser C, Olszewska M, Teruya-Feldstein J, Perumal D, Klimek VM, Spyridonidis A, Rampal RK, Silverman L, Reddy EP, Papaemmanuil E, Parekh S, Greenbaum BD, Leslie CS, Kharas MG, Papapetrou EP.<br \/><strong>Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantabe leukemia.<\/strong><br \/><em>Cell Stem Cell<\/em><span>\u00a0<\/span>2017;20(3):315-328.<span>\u00a0<br \/><\/span><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1934590917300310\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"font-size: 16px\"><b>Read more<\/b><\/a><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221;]<\/p>\n<p>Papapetrou EP.<br \/><strong>Patient-derived induced pluripotent stem cells in cancer research and precision oncology.<\/strong><br \/><em>Nat Med<\/em>. 2016;22(12):1392-1401.<br \/><a href=\"http:\/\/www.nature.com\/nm\/journal\/v22\/n12\/full\/nm.4238.html\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"font-size: 16px\"><b>Read more<\/b><\/a><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221;]<\/p>\n<p>Papapetrou EP.<br \/><strong>Induced pluripotent stem cells,\u00a0past\u00a0and future.<\/strong><span><strong>\u00a0<\/strong><br \/><\/span><em>Science<\/em><span>\u00a0<\/span>2016; 353 (6303): 991-992.<br \/><a href=\"https:\/\/d2ufo47lrtsv5s.cloudfront.net\/content\/353\/6303\/991\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"font-size: 16px\"><b>Read more<\/b><\/a><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221;]<\/p>\n<p>Kotini AG, Chang CJ, Boussaad I, Delrow JJ, Dolezal EK, Nagulapally A, Perna F, Fishbein GA, Klimek VM, Hawkins DR, Huangfu D, Murry CE, Graubert T, Nimer SD, Papapetrou EP.<br \/><strong>Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.\u00a0<\/strong><br \/><em>Nature Biotechnology\u00a0<\/em>2015<span>;33(6):646-55.\u00a0<br \/><\/span><a href=\"https:\/\/www.nature.com\/articles\/nbt.3178\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"font-size: 16px\"><b>Read more<\/b><\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px|||||&#8221;][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;23.3px&#8221; custom_margin=&#8221;-70px|auto|-1px|auto||&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;77.8px&#8221; custom_padding=&#8221;8px|||||&#8221;]<\/p>\n<p style=\"text-align: center\"><span style=\"font-size: large\"><strong>For a complete list of publications<\/strong><strong>\u00a0<\/strong><strong><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Papapetrou+EP\" target=\"_blank\" rel=\"noopener noreferrer\">click here<\/a><\/strong><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Footer Fullwidth &#8211; Section 13&#8243; module_class=&#8221;footer-section&#8221; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#FFFFFF&#8221; background_enable_image=&#8221;off&#8221; max_width=&#8221;100%&#8221; max_width_tablet=&#8221;&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|phone&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;100px|||176px|false|false&#8221; custom_padding=&#8221;3px|0px|0px|0px|false|false&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;bottom&#8221; animation_intensity_slide=&#8221;14%&#8221; animation_starting_opacity=&#8221;100%&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#FFFFFF&#8221; background_color_gradient_direction=&#8221;38deg&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;-134px|auto||147px||&#8221; custom_padding=&#8221;|||0px||&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_social_media_follow _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; text_orientation=&#8221;center&#8221;][et_pb_social_media_follow_network social_network=&#8221;twitter&#8221; url=&#8221;https:\/\/twitter.com\/PapapetrouMDPhD&#8221; icon_color=&#8221;#00AEEF&#8221; use_icon_font_size=&#8221;on&#8221; icon_font_size=&#8221;24px&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_enable_color=&#8221;on&#8221; follow_button=&#8221;off&#8221; url_new_window=&#8221;on&#8221;]twitter[\/et_pb_social_media_follow_network][\/et_pb_social_media_follow][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_font_size=&#8221;24px&#8221;]<\/p>\n<p style=\"text-align: center\"><span style=\"color: #000000\"><strong>Contact Us<\/strong><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#FFFFFF&#8221; background_color_gradient_direction=&#8221;38deg&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;|auto|-2px|auto||&#8221; custom_padding=&#8221;0px||0px|||&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.9.0&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;22px&#8221;]<\/p>\n<p><span style=\"color: #000000\"><b>Resources<\/b><\/span><\/p>\n<p><a href=\"https:\/\/icahn.mssm.edu\/about\/departments\/oncological-sciences\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #00aeef\">Department of Oncological Sciences<\/span><\/a><br \/> <a href=\"https:\/\/icahn.mssm.edu\/research\/black-family-stem-cell\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #00aeef\"> Black Family Stem Cell Institute<\/span><\/a><br \/> <a href=\"https:\/\/icahn.mssm.edu\/research\/tisch\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #00aeef\"> Tisch Cancer Institute<\/span><\/a><br \/> <a href=\"https:\/\/icahn.mssm.edu\/education\/graduate\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #00aeef\"> Graduate School of Biomedical Sciences<\/span><\/a><br \/> <a href=\"https:\/\/www.hematology.org\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #00aeef\"> American Society of Hematology<\/span><\/a><br \/> <a href=\"https:\/\/asgct.org\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #00aeef\"> American Society of Gene and Cell Therapy<\/span><\/a><br \/> <a href=\"https:\/\/www.isscr.org\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #00aeef\"> International Society for Stem Cell Research<\/span><\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221;]<\/p>\n<p><span style=\"color: #000000\"><strong>Papapetrou Lab<br \/> <\/strong>Department of Oncological Sciences<br \/> Icahn School of Medicine at Mount Sinai<br \/> One Gustave L. Levy Place<br \/> Box 1044A<br \/> New York, NY 10029<br \/> Phone: 212-824-9337<br \/> E-mail:<\/span><strong style=\"color: #000000\">\u00a0<\/strong><span style=\"color: #000000\"><span style=\"color: #00aeef\"><a href=\"mailto:eirini.papapetrou@mssm.edu\" style=\"color: #00aeef\">eirini.papapetrou@mssm.edu<\/a><\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221;]<\/p>\n<p><span style=\"color: #000000\"><strong>Courier<br \/> <\/strong><\/span><span style=\"color: #000000\">Hess Center for Science and Medicine<br \/> <\/span><span style=\"color: #000000\">1470 Madison Ave, 6th FL., Rm. 112<br \/> <\/span><span style=\"color: #000000\">New York, NY 10029<br \/> <\/span><span style=\"color: #000000\">Phone: \u00a0212-824-9337<br \/> <\/span>Lab: \u00a0S6-202<\/p>\n<p><span style=\"color: #000000\"><span style=\"font-size: 16px\"><strong>Support Staff<br \/> <\/strong><\/span>Genevieve Joseph<\/span><br \/> <span style=\"color: #000000\"> Administrative Assistant<\/span><br \/> <span style=\"color: #000000\"> Phone: \u00a0212-824-9367<\/span><br \/> <a href=\"mailto:genevieve.joseph@mssm.edu\"><span style=\"color: #00aeef\"> genevieve.joseph@mssm.edu<\/span><\/a><\/p>\n<p><span style=\"font-size: 16px\"><strong><\/strong><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; min_height=&#8221;51.6px&#8221; custom_padding=&#8221;6px|||||&#8221;][et_pb_column _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; type=&#8221;4_4&#8243;][et_pb_button button_text=&#8221;Support Our Lab&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; button_url=&#8221;https:\/\/giving.mountsinai.org\/site\/SPageServer\/;jsessionid=00000000.app20102b?NONCE_TOKEN=4ED6DBF3457A2186683BECC3DC528BA1&amp;pagename=investigators&#8221; url_new_window=&#8221;on&#8221; button_alignment=&#8221;center&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Selected PublicationsKotini AG, Carcamo S, Cruz-Rodriguez N, Olszewska M, Wang T, Demircioglu D, Chang, C-J, Bernard E, Chao MP, Majeati R, Luo H, Kharas MG, Hasson D, Papapetrou EP*. Patient-derived iPSCs Faithfully Represent the Genetic Diversity and Cellular Architecture of Human Acute Myeloid Leukemia. Blood Cancer Discov. In PressRead moreWheeler EC$, Vora S$, Mayer D, [&hellip;]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-2494","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/papapetroulab\/wp-json\/wp\/v2\/pages\/2494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/papapetroulab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/papapetroulab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/papapetroulab\/wp-json\/wp\/v2\/users\/545"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/papapetroulab\/wp-json\/wp\/v2\/comments?post=2494"}],"version-history":[{"count":59,"href":"https:\/\/labs.icahn.mssm.edu\/papapetroulab\/wp-json\/wp\/v2\/pages\/2494\/revisions"}],"predecessor-version":[{"id":5077,"href":"https:\/\/labs.icahn.mssm.edu\/papapetroulab\/wp-json\/wp\/v2\/pages\/2494\/revisions\/5077"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/papapetroulab\/wp-json\/wp\/v2\/media?parent=2494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}