Publications

Panagiotakos G¶ and Yang N¶.

Engineering regional diversity: A morphogen screen for patterned brain organoids.
Cell Stem Cell 2024, Dec 5.

Link

Bertino F, Mukherjee D, Bonora M, Bagowski C, Nardelli J, Metani L, Zanin Venturini DI, Chianese D, Santander N, Salaroglio IC, Hentschel A, Quarta E, Genova T, McKinney AA, Allocco AL, Fiorito V, Petrillo S, Ammirata G, De Giorgio F, Dennis E, Allington G, Maier F, Shoukier M, Gloning KP, Munaron L, Mussano F, Salsano E, Pareyson D, di Rocco M, Altruda F, Panagiotakos G, Kahle KT, Gressens P, Riganti C, Pinton PP, Roos A, Arnold T, Tolosano E, Chiabrando D.

Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus. 
Cell Reports Med 2024, Jul 16.

Link

Meng X, Yao D, Imaizumi K, Chen X, Kelley KW, Reis N, Thete MV, Arjun McKinney A, Kulkarni S, Panagiotakos G, Bassik MC, and Pașca SP.

Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment. 
Nature 2023, Oct.

Link

Andrews MG, Siebert C, Wang L, White ML, Ross J, Morales R, Donnay M, Bamfonga G, Mukhtar T, McKinney AA, Gemenes K, Wang S, Bi Q, Crouch EE, Parikshak N, Panagiotakos G, Huang E, Bhaduri A, and Kriegstein AR.

LIF signaling regulates outer radial glial to interneuron fate during human cortical development. 
Cell Stem Cell 2023, Oct 5.

Link

McKinney AA, Petrova R, and Panagiotakos G.

Calcium and activity-dependent signaling in the developing cerebral cortex.
Development 2022, Sept 1.

Link

Panagiotakos G¶ and Pasca SP¶.

A matter of space and time: Emerging roles of disease-associated proteins in neural development. 
Neuron 2022, Jan 19.

Link

Braun S*, Petrova R*, Tang J, Krokhotin A, Miller E, Tang Y, and Panagiotakos G¶, Crabtree GR¶.

BAF subunit switching regulates chromatin accessibility to control cell cycle exit in the developing mammalian cortex. 
Genes Dev 2021, Mar 1.

Link

Panagiotakos G¶, Haveles C, Arjun A, Petrova R, Rana A, Portmann T, Paşca SP, Palmer TD, Dolmetsch RE.

Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome. 
eLife 2019, Dec 23.

Link

Kastner DB, Ozuysal Y, Panagiotakos G, Baccus SA.

Adaptation of Inhibition Mediates Retinal Sensitization.. 
Curr Biol 2019, Aug 19.

Link

Mayer S, Chen J, Velmeshev D, Mayer A, Eze UC, Bhaduri A, Cunha CE, Jung D, Arjun A, Li E, Alvarado B, Wang S, Lovegren N, Gonzales ML, Szpankowski L, Leyrat A, West JAA, Panagiotakos G, Alvarez-Buylla A, Paredes MF, Nowakowski TJ, Pollen AA, Kriegstein AR..

Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex. 
Neuron 2019, April 3.

Link

Cheli VT, Santiago González DA, Zamora NN, Lama TN, Spreuer V, Rasmusson RL, Bett GC, Panagiotakos G, Paez PM.

Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome. 
Glia 2018, Nov.

Link

Birey F, Andersen J, Makinson CD, Islam S, Wei W, Huber N, Fan HC, Metzler KRC, Panagiotakos G, Thom N, O'Rourke NA, Steinmetz LM, Bernstein JA, Hallmayer J, Huguenard JR, Pasca SP.

Assembly of functionally integrated human forebrain spheroids. 
Nature 2017, May 4.

Link

Leone DP, Panagiotakos G, Heavner WE, Joshi P, Zhao Y, Westphal H, McConnell SK.

Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation. 
Cereb Cortex 2017, Feb 1.

Link

Pasca SP¶, Panagiotakos G¶, Dolmetsch RE¶.

Generating human neurons in vitro and using them to understand neuropsychiatric disease. 
Annu Rev Neurosci 2014, June 23.

Link

View a complete list of our publications here.