{"id":5795,"date":"2022-08-30T11:58:53","date_gmt":"2022-08-30T15:58:53","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/minervalab\/?page_id=5795"},"modified":"2026-10-29T15:16:14","modified_gmt":"2026-10-29T19:16:14","slug":"ldscore","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/minervalab\/resources\/data-ark\/ldscore\/","title":{"rendered":"LDSCORE"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; next_background_color=&#8221;#000000&#8243;][et_pb_fullwidth_menu menu_id=&#8221;14&#8243; menu_style=&#8221;centered&#8221; fullwidth_menu=&#8221;on&#8221; active_link_color=&#8221;#d80b8c&#8221; dropdown_menu_bg_color=&#8221;#221f72&#8243; dropdown_menu_line_color=&#8221;#221f72&#8243; dropdown_menu_active_link_color=&#8221;#d80b8c&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; menu_font=&#8221;|600|||||||&#8221; 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vertical_offset_tablet=&#8221;0&#8243; horizontal_offset_tablet=&#8221;0&#8243; z_index_tablet=&#8221;0&#8243;]<\/p>\n<p><a href=\"https:\/\/labs.icahn.mssm.edu\/minervalab\/scientific-computing-and-data\/\">Scientific Computing and Data<\/a> \/ <a href=\"https:\/\/labs.icahn.mssm.edu\/minervalab\/rds\/\">Research Data Services<\/a> \/\u00a0<a href=\"https:\/\/labs.icahn.mssm.edu\/minervalab\/resources\/data-ark\/\">Data Ark: Data Commons<\/a> \/ LDSCORE<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.9.0&#8243; custom_padding=&#8221;0px||||false|false&#8221; prev_background_color=&#8221;#000000&#8243;][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;|auto|-12px|auto||&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text admin_label=&#8221;Header&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;|700|||||||&#8221; header_text_color=&#8221;#221f72&#8243;]<\/p>\n<h1><strong><span style=\"color: #000080\">LDSCORE<\/span><\/strong><\/h1>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;|auto|35px|auto||&#8221; custom_padding=&#8221;28px|||||&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_line_height=&#8221;1.5em&#8221;]<\/p>\n<h2>Overview<\/h2>\n<p>LD score regression is a reliable and efficient method of using GWAS summary-level data. The data set has been generated from Alkes Price\u2019s group at Harvard and can be publicly downloaded from this<a href=\"https:\/\/alkesgroup.broadinstitute.org\/LDSCORE\"> link<\/a>.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_5,3_5,1_5&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_column type=&#8221;1_5&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][\/et_pb_column][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_image src=&#8221;https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-content\/uploads\/sites\/342\/2022\/08\/nihms718020f2.jpeg&#8221; title_text=&#8221;nihms718020f2&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-48px|||||&#8221;]<\/p>\n<p>[\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_5&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; text_line_height=&#8221;1.5em&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h2>Access<\/h2>\n<p>Effective from January 22, 2024, you must read, agree and sign the <a href=\"https:\/\/dataarkforms.hpc.mssm.edu\/\">Data Use Agreement <\/a>(you must be logged in through the Mount Sinai campus network or secure remote VPN). Access is granted within 24 hours, and on Minerva, you can load module <strong>$ module load dataark <\/strong>to see the path variables.<\/p>\n<h2>More Information<\/h2>\n<p>For more information on this data set, <a href=\"https:\/\/github.com\/bulik\/ldsc\/wiki\/\">click here<\/a> to read more about this study.<\/p>\n<h2>Data Ark Data Sets<\/h2>\n<p>Please visit the <a href=\"https:\/\/labs.icahn.mssm.edu\/minervalab\/resources\/data-ark\/data-ark-data-sets\/\">Data Ark Data Set<\/a> webpage to explore other data sets.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientific Computing and Data \/ Research Data Services \/\u00a0Data Ark: Data Commons \/ LDSCORE LDSCORE Overview LD score regression is a reliable and efficient method of using GWAS summary-level data. The data set has been generated from Alkes Price\u2019s group at Harvard and can be publicly downloaded from this link. Access Effective from January 22, [&hellip;]<\/p>\n","protected":false},"author":415,"featured_media":0,"parent":1321,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-5795","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/pages\/5795","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/users\/415"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/comments?post=5795"}],"version-history":[{"count":20,"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/pages\/5795\/revisions"}],"predecessor-version":[{"id":15695,"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/pages\/5795\/revisions\/15695"}],"up":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/pages\/1321"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/media?parent=5795"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}