{"id":12620,"date":"2025-10-24T16:30:14","date_gmt":"2025-10-24T20:30:14","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/minervalab\/?page_id=12620"},"modified":"2026-03-04T10:26:25","modified_gmt":"2026-03-04T15:26:25","slug":"air%c2%b7ms-ai-agent","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/minervalab\/air%c2%b7ms-ai-agent\/","title":{"rendered":"AIR\u00b7MS AI Agent"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; inner_width=&#8221;auto&#8221; inner_max_width=&#8221;1080px&#8221;][et_pb_row][et_pb_column type=&#8221;4_4&#8243; custom_padding__hover=&#8221;|||&#8221; custom_padding=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Breadcrumb&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; background_pattern_color=&#8221;rgba(0,0,0,0.2)&#8221; background_mask_color=&#8221;#ffffff&#8221; text_text_shadow_horizontal_length=&#8221;text_text_shadow_style,%91object Object%93&#8243; text_text_shadow_horizontal_length_tablet=&#8221;0px&#8221; 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header_3_text_shadow_blur_strength_tablet=&#8221;1px&#8221; header_4_text_shadow_horizontal_length=&#8221;header_4_text_shadow_style,%91object Object%93&#8243; header_4_text_shadow_horizontal_length_tablet=&#8221;0px&#8221; header_4_text_shadow_vertical_length=&#8221;header_4_text_shadow_style,%91object Object%93&#8243; header_4_text_shadow_vertical_length_tablet=&#8221;0px&#8221; header_4_text_shadow_blur_strength=&#8221;header_4_text_shadow_style,%91object Object%93&#8243; header_4_text_shadow_blur_strength_tablet=&#8221;1px&#8221; header_5_text_shadow_horizontal_length=&#8221;header_5_text_shadow_style,%91object Object%93&#8243; header_5_text_shadow_horizontal_length_tablet=&#8221;0px&#8221; header_5_text_shadow_vertical_length=&#8221;header_5_text_shadow_style,%91object Object%93&#8243; header_5_text_shadow_vertical_length_tablet=&#8221;0px&#8221; header_5_text_shadow_blur_strength=&#8221;header_5_text_shadow_style,%91object Object%93&#8243; header_5_text_shadow_blur_strength_tablet=&#8221;1px&#8221; header_6_text_shadow_horizontal_length=&#8221;header_6_text_shadow_style,%91object Object%93&#8243; header_6_text_shadow_horizontal_length_tablet=&#8221;0px&#8221; header_6_text_shadow_vertical_length=&#8221;header_6_text_shadow_style,%91object Object%93&#8243; header_6_text_shadow_vertical_length_tablet=&#8221;0px&#8221; header_6_text_shadow_blur_strength=&#8221;header_6_text_shadow_style,%91object Object%93&#8243; header_6_text_shadow_blur_strength_tablet=&#8221;1px&#8221; box_shadow_horizontal_tablet=&#8221;0px&#8221; box_shadow_vertical_tablet=&#8221;0px&#8221; box_shadow_blur_tablet=&#8221;40px&#8221; box_shadow_spread_tablet=&#8221;0px&#8221; vertical_offset_tablet=&#8221;0&#8243; horizontal_offset_tablet=&#8221;0&#8243; z_index_tablet=&#8221;0&#8243;]<\/p>\n<h1 data-start=\"68\" data-end=\"146\"><span style=\"color: #00aeef\"><strong><span data-teams=\"true\">AIR\u00b7MS AI Agent: <\/span>How Large Language Models Work (and Why Users Should Verify Their Responses)<\/strong><\/span><\/h1>\n<p>\u00a0<\/p>\n<ul>\n<li data-start=\"295\" data-end=\"764\"><span style=\"color: #000000\">The AIR\u00b7MS AI Agent uses Large Language Models (LLMs).<\/span><\/li>\n<li data-start=\"295\" data-end=\"764\"><span style=\"color: #000000\">LLMs such as <strong data-start=\"332\" data-end=\"342\">Ollama<\/strong> (Meta), <strong data-start=\"351\" data-end=\"360\">Gemma<\/strong> (Google), and <strong data-start=\"375\" data-end=\"382\">Phi<\/strong> (Microsoft)\u2014are advanced artificial intelligence systems built on a type of neural network architecture known as <strong data-start=\"496\" data-end=\"512\">transformers<\/strong>. <\/span><\/li>\n<li data-start=\"295\" data-end=\"764\"><span style=\"color: #000000\">Transformers enable models to process and generate text by considering the relationships between words and concepts across long passages of text, allowing them to capture context and meaning far more effectively than earlier neural network designs.<\/span><\/li>\n<li data-start=\"766\" data-end=\"1147\"><span style=\"color: #000000\">These models are trained on vast amounts of text from books, articles, websites, and other sources. Through training, they learn patterns in language and how words and ideas relate to one another. <\/span><\/li>\n<li data-start=\"766\" data-end=\"1147\"><span style=\"color: #000000\">When a user provides a prompt, the model predicts the most likely next words based on these learned patterns, producing text that is coherent, relevant, and contextually appropriate.<\/span><\/li>\n<li data-start=\"1149\" data-end=\"1603\"><span style=\"color: #000000\">However, while LLMs are powerful tools for writing, research, and problem-solving, they do not \u201cunderstand\u201d information in the human sense or have access to verified facts. <\/span><\/li>\n<li data-start=\"1149\" data-end=\"1603\"><span style=\"color: #000000\">Their responses are <strong data-start=\"1342\" data-end=\"1379\">probabilistic rather than factual<\/strong>, meaning they can occasionally produce incorrect, outdated, or even fabricated information\u2014an issue known as <strong data-start=\"1489\" data-end=\"1506\">hallucination<\/strong>. These errors can be convincing because the models are designed to sound confident and fluent.<\/span><\/li>\n<\/ul>\n<p data-start=\"1605\" data-end=\"1678\"><span style=\"color: #000000\">Further reading on hallucinations, particularly in biomedical contexts, are available here:<\/span><\/p>\n<ul>\n<li data-start=\"649\" data-end=\"1103\"><a href=\"https:\/\/www.nature.com\/articles\/s43856-025-01021-3\"><span style=\"color: #00aeef\">Multi-model assurance analysis showing large language models are highly vulnerable to adversarial hallucination attacks during clinical decision support | Communications Medicine<\/span><\/a><\/li>\n<li data-start=\"649\" data-end=\"1103\"><span style=\"color: #00aeef\"><a style=\"color: #00aeef\" href=\"https:\/\/www.nature.com\/articles\/s41746-025-01670-7\">A framework to assess clinical safety and hallucination rates of LLMs for medical text summarization | npj Digital Medicine<\/a><\/span><\/li>\n<li data-start=\"649\" data-end=\"1103\"><a href=\"https:\/\/studyfinds.org\/chatgpts-hallucination-problem-fabricated-references\/\"><span style=\"color: #00aeef\">ChatGPT\u2019s Hallucination Problem: Study Finds More Than Half Of AI\u2019s References Are Fabricated Or Contain Errors<\/span><\/a><\/li>\n<\/ul>\n<p data-start=\"1999\" data-end=\"2408\"><span style=\"color: #000000\">Because of this, users should <strong data-start=\"2029\" data-end=\"2081\">always verify important facts, data, and sources<\/strong> when using LLMs\u2014especially for academic, professional, or decision-making purposes. Cross-referencing information with trusted references or original sources helps ensure accuracy. Used responsibly, LLMs can be highly effective assistants, but <strong data-start=\"2326\" data-end=\"2362\">human judgment remains essential<\/strong> for verifying and interpreting their outputs.<\/span><\/p>\n<hr data-start=\"2410\" data-end=\"2413\" \/>\n<h2 data-start=\"2415\" data-end=\"2456\">\u00a0<\/h2>\n<h2 data-start=\"2415\" data-end=\"2456\"><strong><span style=\"color: #00aeef\">Situations That Require Fact-Checking<\/span><\/strong><\/h2>\n<p data-start=\"2458\" data-end=\"2521\"><span style=\"color: #000000\">AIR\u00b7MS AI Agent users should be especially cautious in the following scenarios (although this is by no means limited to this selection):<\/span><\/p>\n<ul data-start=\"2523\" data-end=\"3318\">\n<li data-start=\"2523\" data-end=\"2808\">\n<p data-start=\"2525\" data-end=\"2808\"><span style=\"color: #000000\"><strong data-start=\"2525\" data-end=\"2551\">Lists of medical codes<\/strong> (diagnoses, procedures, drugs, etc.):<\/span><br data-start=\"2589\" data-end=\"2592\" \/><span style=\"color: #000000\">LLMs may generate inaccurate or nonexistent codes. Verify all lists against peer-reviewed or authoritative resources. Future improvements may incorporate retrieval-augmented generation (RAG) to reduce this issue.<\/span><\/p>\n<\/li>\n<li data-start=\"2810\" data-end=\"3017\">\n<p data-start=\"2812\" data-end=\"3017\"><span style=\"color: #000000\"><strong data-start=\"2812\" data-end=\"2853\">Clinical decision support information<\/strong> (e.g., drug suggestions, interventions, differential diagnoses):<\/span><br data-start=\"2918\" data-end=\"2921\" \/><span style=\"color: #000000\">Always confirm outputs with up-to-date clinical references before applying them in practice.<\/span><\/p>\n<\/li>\n<li data-start=\"3019\" data-end=\"3195\">\n<p data-start=\"3021\" data-end=\"3195\"><span style=\"color: #000000\"><strong data-start=\"3021\" data-end=\"3039\">Generated code<\/strong> (e.g., SQL, Python, or R):<\/span><br data-start=\"3066\" data-end=\"3069\" \/><span style=\"color: #000000\">Review and test all generated code to ensure it performs as intended and adheres to security and data integrity standards.<\/span><\/p>\n<\/li>\n<li data-start=\"3197\" data-end=\"3318\">\n<p data-start=\"3199\" data-end=\"3318\"><span style=\"color: #000000\"><strong data-start=\"3199\" data-end=\"3251\">Any information that might impact clinical care:<\/strong><\/span><br data-start=\"3251\" data-end=\"3254\" \/><span style=\"color: #000000\">Verify through reliable medical sources before acting on it.<\/span><\/p>\n<\/li>\n<\/ul>\n<h2>\u00a0<\/h2>\n<h2><span style=\"color: #00aeef\"><strong>Feedback<\/strong><\/span><\/h2>\n<p><span style=\"color: #000000\">We are committed to improving the AIR\u00b7MS AI Agent by incorporating RAG methods, keeping models current, and identifying key areas where responses may be unreliable.<\/span><\/p>\n<p><span style=\"color: #000000\">If you have any comments or questions, please do not hesitate to reach out to<\/span> <a href=\"mailto:andrew.deonarine@mssm.edu\">Andrew Deonarine<\/a> or <a href=\"mailto:edwin.thrower@mssm.edu\">Edwin Thrower<\/a>.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p><div class=\"et_pb_row et_pb_row_0 et_pb_row_empty\">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div> Scientific Computing and Data \/ AIR\u00b7MS (AI Ready Mount Sinai) \/ AIR\u00b7MS AI Agent \/\u00a0 AIR\u00b7MS AI Agent: How Large Language Models Work (and Why Users Should Verify Their Responses)\u00a0The AIR\u00b7MS AI Agent uses Large Language Models (LLMs).LLMs such as Ollama (Meta), Gemma (Google), and Phi (Microsoft)\u2014are advanced artificial intelligence systems built on a [&hellip;]<\/p>\n","protected":false},"author":699,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-12620","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/pages\/12620","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/users\/699"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/comments?post=12620"}],"version-history":[{"count":14,"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/pages\/12620\/revisions"}],"predecessor-version":[{"id":13436,"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/pages\/12620\/revisions\/13436"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/minervalab\/wp-json\/wp\/v2\/media?parent=12620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}