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Transcriptional Control of Tissue Phagocytes:

       The Immgen Consortia is an NIH funded consortia with the goal of establishing the immune profile of hematopoietic cells in mice in the steady state and upon inflammatory challenges. Our laboratory focuses on dissecting the transcriptional network that controls the differentiation and function of tissue dendritic cells and, through the consortia, we use the Broad Institute’s facility to perform both microarray and RNAseq, and also microRNA and potentially proteomics profiling of tissue phagocytes.  This project provides a unique opportunity to perform multiscale analysis of specific tissue phagocyte populations in the steady state and inflamed state, across the entire hematopoietic compendium.