{"id":35,"date":"2016-07-03T20:39:37","date_gmt":"2016-07-03T20:39:37","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/margarethbaron-lab\/?page_id=35"},"modified":"2020-06-26T20:02:16","modified_gmt":"2020-06-26T20:02:16","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/margaretbaron-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243;][et_pb_row][et_pb_column type=&#8221;2_3&#8243;][et_pb_text _builder_version=&#8221;3.19.10&#8243;]<\/p>\n<p><a href=\"https:\/\/labs.icahn.mssm.edu\/margarethbaron-lab\/wp-content\/uploads\/sites\/186\/2016\/07\/BaronLab-Publications-Fig1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-86 aligncenter\" src=\"https:\/\/labs.icahn.mssm.edu\/margarethbaron-lab\/wp-content\/uploads\/sites\/186\/2016\/07\/BaronLab-Publications-Fig1.jpg\" alt=\"BaronLab-Publications-Fig1\" width=\"200\" height=\"260\" \/><\/a><br \/><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong>, Evans, D.R., and W.N. Lipscomb (1979) The Location and Local Environment of the Active Sites of Aspartate Transcarbamylase of Escherichia coli. J. Biol. Chem. 254: 10686-10693.<\/span><\/p>\n<p><span style=\"color: #333333\">Das Gupta, A., <strong>Baron, M.H.<\/strong>, and D. Baltimore (1979) Poliovirus replicase: A soluble enzyme able to initiate copying of poliovirus RNA. Proc. Natl. Acad. Sci. U.S.A. 76: 2679-2683.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and D. Baltimore (1982) Antibodies Against the Chemically Synthesized Genome-Linked Protein of Poliovirus React with Native Virus-Specific Proteins. Cell 28: 395-404.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and D. Baltimore (1982) Purification and Properties of a Host Cell Protein Required for Poliovirus Replication in Vitro. J.Biol. Chem. 257: 12351-12358.<\/span><br \/><span style=\"color: #333333\">Baron, M.H. and D. Baltimore (1982) In Vitro Copying of Viral Positive Strand RNA by Poliovirus Replicase: Characterization of the Reaction and its Products. J. Biol. Chem. 257: 12359-12366.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and D. Baltimore (1982) Antibodies Against a Synthetic Peptide of Poliovirus Replicase Protein: Reaction with Native, Virus-Encoded Proteins and Inhibition of Virus-Specific Polymerase Activities in Vitro J. Virol. 43: 969-978.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and D. Baltimore (1982) Anti-VPg Antibody Inhibition of the Poliovirus Replicase Reaction and Production of Covalent Complexes of VPg-Related Polypeptides and Newly-Made RNA. Cell 30: 745-752.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and T. Maniatis (1986) Rapid Reprogramming of Globin Gene Expression in Transient Heterokaryons. Cell 46: 591-602.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and T. Maniatis (1987) Stage-Specific Reprogramming of Globin Gene Expression. Progr. Clin. Biol. Res. 251: 271-284.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and T. Maniatis (1987) Reprogramming of Globin Gene Expression in Interspecific Heterokaryons. In Molecular Approaches to Developmental Biology, Alan R. Liss, Inc.,pp. 469-476.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and T. Maniatis (1991) Regulated Expression of Human a- and b-Globin Genes in Transient Heterokaryons. Mol. Cell. Biol. 11: 1239-1247.<\/span><\/p>\n<p><span style=\"color: #333333\">Trepicchio, W.L., Dyer, M.A. and <strong>M.H. Baron<\/strong> (1993) Developmental regulation of the human embryonic b-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elements, Mol. Cell. Biol. 13 : 7457-7468.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (1993) Reversibility of the Differentiated State in Somatic Cells. Current Opinion Cell Biol. 5: 1050-1056, Current Biology Ltd., London.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and S.M. Farrington (1994) Positive regulators of the lineage-specific transcription factor GATA-1 in differentiating erythroid cells, Mol. Cell. Biol.14: 3108-3114.<\/span><\/p>\n<p><span style=\"color: #333333\">Trepicchio, W.L., Dyer, M.A., and <strong>M.H. Baron<\/strong> (1994) A novel developmental regulatory motif required for stage-specific activation of the e-globin gene and nuclear factor binding in embryonic erythroid cells, Mol. Cell. Biol. 14: 3763-3771.<\/span><\/p>\n<p><span style=\"color: #333333\">Trepicchio, W.L., Dyer, M.A., Hardison, R.C., and <strong>M.H. Baron<\/strong> (1994) Upstream regulatory region of the human embryonic b-like globin gene, e, DNA Sequence 4: 409-412.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (1994) Embryonic Erythroid Differentiation and Development. Symp. European School of Molec. Med. (Signal Transduction in Differentiation and Trans-Differentiation), Brescia, Italy.<\/span><\/p>\n<p><span style=\"color: #333333\">Lister, J., Forrester, W.C., and <strong>M.H. Baron<\/strong> (1995) Inhibition of an erythroid differentiation switch by the helix-loop-helix protein, Id1. J. Biol. Chem. 270 : 17939-17946.<\/span><\/p>\n<p><span style=\"color: #333333\">Dyer, M.A., W.L. Trepicchio, M. Belaoussoff, S.M. Farrington, and <strong>M.H. Baron<\/strong> (1995) Molecular Mechanisms of Embryonic b-Like Globin Gene Regulation During Mammalian Development. Hemoglobin Switching, vol. 1, Intercept Ltd., pp. 135-151.<\/span><\/p>\n<p><span style=\"color: #333333\">Dyer, M.A., Naidoo, R., Hayes, P.J., Larson, C.J., Verdine, G.L. and <strong>M.H. Baron<\/strong> (1996) A DNA bending protein interacts with an essential upstream regulatory element of the human embryonic \uf062-like globin gene. Mol. Cell. Biol. 16: 829-838.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (1996) Developmental Regulation of the Vertebrate Globin Multigene Family. Gene Expression 6: 129-137.<\/span><\/p>\n<p><span style=\"color: #333333\">Farrington, S.M., Belaoussoff, M. and <strong>M.H. Baron<\/strong> (1997) Winged helix, hedgehog, and Bmp genes are differentially restricted to functionally distinct tissue layers within the murine embryonic yolk sac. Mech. Develop. 62: 197-211.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (1997) Transcriptional control of globin gene expression during vertebrate development. Biochim. Biophys. Acta 1351: 51-72.<\/span><\/p>\n<p><span style=\"color: #333333\">Lister, J. and <strong>M.H. Baron<\/strong> (1998) Induction of basic-helix-loop-helix protein-containing complexes during erythroid differentiation. Gene Expression 7: 25-38.<\/span><\/p>\n<p><span style=\"color: #333333\">Dyer, M.A., Hayes, P.J., and <strong>M.H. Baron<\/strong> (1998) The HMG domain protein SSRP1\/PREIIBF is involved in activation of the human embryonic b-like globin gene. Mol. Cell Biol. 18: 2617- 2628.<\/span><\/p>\n<p><span style=\"color: #333333\">Belaoussoff, M., Farrington, S.M. and <strong>M.H. Baron<\/strong> (1998) Hematopoietic Induction and Respecification of A-P Identity by Visceral Endoderm Signaling in the Mouse Embryo. Development 125: 5009- 5018.<\/span><\/p>\n<p><span style=\"color: #333333\">Spencer, J. A., Baron, M. H., and Olson, E. N. (1999) Cooperative Transcriptional Activation by\u00a0Serum Response Factor and the High Mobility Group Protein SSRP1. J. Biol. Chem. 274: 15686-15693.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2000) Interaction of endoderm and ectoderm in embryonic hematopoiesis. Exper. Hematol. 28: 129-.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2001) Embryonic Induction of Mammalian Hematopoiesis and Vasculogenesis. In: L. Zon, ed. Hematopoiesis, Chapter 13, New York, Oxford University Press, pp. 160-170.<\/span><\/p>\n<p><span style=\"color: #333333\">Dyer, M.A., Farrington, S.M., Mohn, D., Munday, J., and <strong>M.H. Baron<\/strong> (2001) Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. Development 128: 1717-1730.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2001) Induction of Embryonic Hematopoietic and Endothelial Stem\/Progenitor Cells by Hedgehog-Mediated Signals. Differentiation 69: 175-185.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2001) Molecular Regulation of Embryonic Hematopoiesis and Vascular Development: A Novel Pathway. J. Hematother. Stem Cell Res. (now Stem Cells and Development) 10: 587- 594.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and Mitus, A.J. (2002) Chapter 15: Blood Disorders. In: K. Carlson and S.A. Eisenstadt,\u00a0eds. Primary Care of Women, 2nd Ed., St. Louis, Mosby-Year Book, Inc., pp. 142-150.<\/span><\/p>\n<p><span style=\"color: #333333\">Sahr, K., Dias, D., Sanchez, R., Chen, D., Chen, S., Gudas, L. and <strong>M.H. Baron<\/strong> (2002). Structure, upstream promoter region, and functional domains of a mouse and human Mix paired-like homeobox gene. Gene 291: 135-147.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2002) Activation of Hematopoiesis and Vasculogenesis in the Mouse Embryo: Induction and Reprogramming of Ectodermal Cell Fate by Signals from Primitive Endoderm. In: Eaton, G.R., Wiley, D.C., and Jardetsky, O., eds. Structures and Mechanisms: From Ashes to Enzymes (ACS Symposium Series), Vol. 827 (Washington, DC, American Chemical Society), pp. 294-308.<\/span><\/p>\n<p><span style=\"color: #333333\">Jones, E.A.V., D. Crotty, P. Kulesa, C.W. Waters, <strong>M.H. Baron<\/strong>, S.E. Fraser, M.E. Dickinson (2002) Dynamic In Vivo Imaging of Post-Implantation Mammalian Embryos Using Whole Embryo Culture. Genesis 34: 228-235.<\/span><\/p>\n<p><span style=\"color: #333333\">Mohn, D., Chen, S., Dias, D., Weinstein, D., Dyer, M.A., Sahr, K., Ducker, C.E., Zahradka, K.E., Keller, G., Zaret, K.S., Gudas, L. and <strong>M.H. Baron (<\/strong>2003) The mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Developmental Dynamics 226: 446-459.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2003) Embryonic Origins of Mammalian Hematopoiesis. Experimental Hematology, 31: 1160-1169.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2004) Hemangioblasts in Adults? [&#8220;Inside Blood,&#8221; invited commentary] Blood 103: 1.<\/span><\/p>\n<p><span style=\"color: #333333\">Jones, E.A.V., <strong>Baron, M.H.<\/strong>, Fraser, S.E., and Dickinson, M.E. (2004) Measuring Hemodynamic Changes During Mammalian Development. Amer. J. Physiol. 287: H1561-H1569.<\/span><\/p>\n<p><span style=\"color: #333333\">Snyder, A., Fraser, S.T., and <strong>Baron, M.H.<\/strong> (2004) Bone Morphogenetic Proteins in Vertebrate Hematopoietic Development. J. Cellular Biochem. 93: 224-232. Cover article.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (ed.) (2005) Developmental Regulation of Hematopoiesis: Methods and Protocols. Methods in Molecular Medicine series, New York, Humana Press.<\/span><br \/><span style=\"color: #333333\">\u2022 This publication was highlighted in a review by de Bruijn, M. (2005) Developmental hematopoiesis from fly to human. Development 132: 5128-5130.<\/span><\/p>\n<p><span style=\"color: #333333\">Jones, E.A.V., Crotty, D., <strong>Baron, M.H.<\/strong>, Fraser, S.E. and Dickinson, M.E. (2005) Dynamic In Vivo Imaging of Mammalian Hemato-Vascular Development Using Whole Embryo Culture. Developmental Regulation of Hematopoiesis: Methods and Protocols, ed. Baron, M.H., Methods in Molecular Medicine series, New York, Humana Press, pp. 381-393.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and Mohn, D. (2005) Mouse Embryonic Explant Culture System for Analysis of Hematopoietic and Vascular Development. In Developmental Regulation of Hematopoiesis: Methods and Protocols, ed. Baron, M.H., Methods in Molecular Medicine series, New York, Humana Press, pp. 231-256.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> and Fraser, S.T. (2005) The Specification of Early Hematopoiesis in the Mammal. I. Lemischka, ed. Current Opinion in Hematology 12: 217-221.<\/span><\/p>\n<p><span style=\"color: #333333\">Fraser, S.T., Hadjantonakis, K., Willey, S., Sahr, K.E., Kelly, O.G., Jones, E.A.V., Dickinson, M.E., and <strong>Baron, M.H.<\/strong> (2005) Using a Histone Yellow Fluorescent Protein Fusion for Tagging and Tracking Endothelial Cells in ES Cells and Mice. Genesis 42: 162-171.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2005) Early Patterning of the Mouse Embryo: Implications for Hematopoietic Commitment and Differentiation. Experimental Hematology 33: 1015-1020.<\/span><\/p>\n<p><span style=\"color: #333333\">Willey, S., Ayuso-Sacido, A., Zhang, H., Fraser, S.T., Adlam, M.A., Sahr, K., Kyba, M., Daley, G.Q., Keller, G., and <strong>Baron, M.H.<\/strong> (2006) Acceleration of Mesoderm Development and Expansion of Hematopoietic Progenitors in Differentiating ES Cells by the Mouse Mix-Like Homeodomain Transcription Factor. Blood 107: 3122-3130. First Edition Paper, January 10, 2006; DOI 10.1182\/blood-2005-10-4120. PMCID: PMC1784910<\/span><\/p>\n<p><span style=\"color: #333333\">Kwon, G., Fraser, S.T., Eakin, G., Mangano, M., Isern, J., Sahr, K.E., Hadjantonakis, A.-K., and <strong>Baron, M.H.<\/strong> (2006) Tg(Afp-GFP) Expression Marks Primitive and Definitive Endoderm Lineages during Mouse Development. Developmental Dynamics 235: 2549-2558. Epub ahead of press.<\/span><\/p>\n<p><span style=\"color: #333333\">Fraser, S.T., Isern, J. and <strong>Baron, M.H.<\/strong> (2007) Maturation and enucleation of primitive erythroblasts is accompanied by changes in cell surface antigen expression patterns during mouse embryogenesis. Blood 109: 343-352. First Edition Paper, August 29, 2006; DOI 10.1182\/blood- 2006-03-006569.<\/span><\/p>\n<p><span style=\"color: #333333\">Haremaki, T., Fraser, S.T., Kuo, Y.-M., <strong>Baron, M.H.<\/strong>, and Weinstein, D.C. (2007) Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc. Natl. Acad. Sci. U.S.A. 104: 12029-12034. Early Edition, 10.1073_pnas0701413104.<\/span><\/p>\n<p><span style=\"color: #333333\">Durand, C., Robin, C., Bollerot, K., <strong>Baron, M.H.<\/strong>, Ottersbach, K., and Dzierzak, E. (2007) Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells, Proc. Natl. Acad. Sci. U.S.A. 104: 20838-20843.<\/span><br \/><span style=\"color: #333333\">Baron, M.H. (2008) The wanderings of hematopoietic stem cells. Blood 111: 3307-3308 [&#8220;Inside Blood,&#8221; invited commentary].<\/span><\/p>\n<p><span style=\"color: #333333\">Isern, J., Fraser, S.T., He, Z. and <strong>Baron, M.H.<\/strong> (2008) The fetal liver is a niche for maturation of primitive erythroid cells. Proc. Natl. Acad. Sci. U.S.A. 105: 6662-6667. [Also see &#8220;This Week in PNAS\/In This Issue&#8221;]<\/span><\/p>\n<p><span style=\"color: #333333\">Larina, I.V., Shen, W., Kelly, O.G., Hadjantonakis, A.-K., <strong>Baron, M.H.<\/strong>, and Dickinson, M.E. (2009) A membrane associated mCherry fluorescent reporter line for studying vascular remodeling and cardiac function during murine embryonic development. The Anatomical Record 292: 333-3341.<\/span><\/p>\n<p><span style=\"color: #333333\">Fraser, S.T. and <strong>Baron, M.H.<\/strong> (2009) Embryonic fates for extraembryonic lineages: new perspectives. J. Cellular Biochem., 107: 586-591.<\/span><\/p>\n<p><span style=\"color: #333333\">Zhang, H., Fraser, S.T., Papazoglu, C., Hoatlin, M.E., and <strong>Baron, M.H.<\/strong> (2009) The Mouse Mesendoderm Gene Goosecoid is a Transcriptional Target of the Mixl1 Homeodomain Protein in Differentiating Embryonic Stem Cells. Stem Cells 27: 2884-2895. [Epub ahead of print] PMID: 19711456.<\/span><\/p>\n<p><span style=\"color: #333333\">Isern, J., Fraser, S.T., He, Z. and <strong>Baron, M.H.<\/strong> (2010) Developmental niches for embryonic erythroid cells. Blood Cells, Molecules and Diseases 44: 207-208, DOI 10.1016\/j.bcmd.2010.02.008. PMCID: PMC2846976.<\/span><\/p>\n<p><span style=\"color: #333333\">Fraser, S.T., Isern, J. and <strong>Baron, M.H.<\/strong> (2010) Use of transgenic fluorescent reporter mouse lines to monitor hematopoietic and erythroid development during embryogenesis. Methods in Enzymology, P. Wassarman and P. Soriano, eds. [invited chapter], vol. 476, pp. 403-427. PMID: 20691878.<\/span><\/p>\n<p><span style=\"color: #333333\">Isern, J., Fraser, S.T., He, Z., Zhang, H., and <strong>Baron, M.H.<\/strong> (2010) Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf. Blood 116: 3972-3980. DOI 10.1182\/blood-2010-04-281196. PMID:20720183. Cover article.<\/span><\/p>\n<p><span style=\"color: #333333\">Isern, J., He, Z., Fraser, S.T., Nowotschin, S., Ferrer-Vaquer, A., Moore, R., Hadjantonakis, A.-K., Schulz, V., Tuck, D., Gallagher, P.G., and <strong>Baron, M.H.<\/strong> (2011) Single Lineage Transcriptome Analysis Reveals Key Regulatory Pathways in Primitive Erythroid Progenitors in the Mouse Embryo, Blood 117: 4924-4934, First Edition Paper, prepublished online January 24, 2011;DOI 10.1182\/blood-2010-10-313676. PMID: 21263157. Cover article.<\/span><br \/><span style=\"color: #333333\">\u2022 This article was highlighted in the commentary Inside Blood, Mullner, E. Erythropoiesis: early, not primitive. Blood 117: 4685-4686.<\/span><\/p>\n<p><span style=\"color: #333333\">Artus, J., Douvaras, P., Piliszek, A., Isern, J., <strong>Baron, M.H.<\/strong> and Hadjantonakis, A.-K. BMP4 signalling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity, Developmental Biology 361: 245-262. PMID: 22051107.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong>, Isern, J. and Fraser, S. (2012) The embryonic origins of erythropoiesis in mammals. Blood 119: 4828-4837 [Invited review]. PMID: 22337720<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2013) Early Embryonic Erythropoiesis \u2026 Not so Primitive After All. Stem Cells 31: 849-856, doi: 10.1002\/stem.1342. [Epub ahead of print] PMCID: PMC3637392 [Invited review].<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong>, Vacaru, A., and Nieves, J. (2013) Erythroid Development in the Mammalian Embryo. Blood Cells, Molecules and Diseases 51(4): 213-219, ed. J. Palis, [Invited review].<\/span><\/p>\n<p><span style=\"color: #333333\">Vacaru, A., Isern, J., Fraser, S.T., and <strong>Baron, M.H.<\/strong> (2013) Analysis of primitive erythroid cell proliferation and enucleation using a cyan fluorescent reporter in transgenic mice. Genesis 51(11): 751-62. doi: 10.1002\/dvg.22420. Epub 2013 Aug 30. [Epub ahead of print] PMID: 23913596. Cover article.<\/span><\/p>\n<p><span style=\"color: #333333\">Zhang, H., Nieves, J.L., Fraser, S.T., Isern, J., Douvaras, P., Papatsenko, D., D&#8217;Souza, S., Lemischka, I.R., Dyer, M.A., and <strong>Baron, M.H.<\/strong> (2013) Expression of Podocalyxin separates the hematopoietic and vascular potentials of mouse ES cell-derived mesoderm. Stem Cells Cells 32(1): 191-203, DOI: 10.1002\/stem.1536 [Epub ahead of print]<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.<\/strong> (2013) The TRIMming on an erythroid receptor complex. Blood 122: 3701-3702 [&#8220;Inside Blood,&#8221; invited commentary].<\/span><\/p>\n<p><span style=\"color: #333333\">Pulina, M.V., Sahr, K.E., <strong>Baron, M.H.*<\/strong>, and Hadjantonakis, A.-K.* (2014) A conditional mutant allele for analysis of Mixl1 function in the mouse. Genesis 52: 417-423. * Joint corresponding authors.\u00a0PMID: 24596343<\/span><\/p>\n<p><span style=\"color: #333333\">Vacaru, A., Vitale, J., Nieves, J., and <strong>Baron, M.H.<\/strong> (2014) Generation of Transgenic Mouse Fluorescent Reporter Lines for Studying Hematopoietic Development. Methods Mol. Biol. 1194: 289-312, S.R. Singh, ed. (New York, Springer and Humana Press). DOI 10.1007\/978-1-4939-1215-5_16 [Invited chapter].<\/span><\/p>\n<p><span style=\"color: #333333\">Zhang, X., Camprecios, G., Rimmele, P., Liang, R., Yalcin, S., Mungamuri, S.K., Barminko, J., D&#8217;Escamard, V., <strong>Baron, M.H.<\/strong>, Brugnara, C., Papatsenko, D., Rivella, S., and Ghaffari, S. (2014). FOXO3-mTOR Metabolic Cooperation in the Regulation of Erythroid Cell Maturation and Homeostasis. Am J Hematol. 89(10): 954-963. Prepublished on 2014\/06\/27 as DOI 10.1002\/ajh.23786 PMID:24966026<\/span><\/p>\n<p><span style=\"color: #333333\">Fan, Y., Li, X., Fu, J., Harris, R., Lindenmeyer, M., Cohen, C.D., Guillot, N., <strong>Baron, M.H.<\/strong>, Kyung, L., He, C., Schlondorff, D. and Chuang, P.Y. (2015) BAMBI elimination enhances non-canonical glomerular ERK1\/2 and Smad1\/5 signaling and glomerular dysfunction in diabetic mice. Diabetes 64<em>: <\/em>2220-2233.\u00a0 PMCID: PMC4439561.<\/span><\/p>\n<p><span style=\"color: #333333\">Mercurio, S., S. Petrillo, D. Chiabrando, Z. I. Bassi, D. Gays, A. Camporeale, A. Vacaru, B. Miniscalco, G. Valperga, L. Silengo, F. Altruda, <strong>M. H. Baron<\/strong>, M. M. Santoro and E. Tolosano (2015). &#8220;The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation.&#8221; <em>Haematologica<\/em> <em>100(6)<\/em>: 720-729.\u00a0 PMCID: <a style=\"color: #333333\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4450617\/\">PMC4450617<\/a>.<\/span><\/p>\n<p><span style=\"color: #333333\">Lohmann, F., Dangeti, M.,\u00a0 Soni, S., Chen, X., Planutis, A., <strong>Baron, M.H.,<\/strong> Choi, K.C., and Bieker, J.J. (2015) The DEK Oncoprotein Is a Critical Component of the EKLF\/KLF1 Enhancer in Erythroid Cells. <em>Mol. Cell. Biol.<\/em> <em>35: <\/em>3726-3738.\u00a0 PMCID:\u00a0 PMC4589598.<\/span><\/p>\n<p><span style=\"color: #333333\">Barminko, J., Reinholt, B., and <strong>Baron, M.H.\u00a0 <\/strong>(2016)<strong>\u00a0 <\/strong>Development and differentiation of the erythroid lineage in mammals.\u00a0 <em>Developmental &amp; Comparative Immunology<\/em> <em>58:<\/em> 18-29.\u00a0 PMCID: <a style=\"color: #333333\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4775370\/\">PMC4775370<\/a>.<\/span><\/p>\n<p><span style=\"color: #333333\"><strong>Baron, M.H.,<\/strong> and Barminko, J. (2016). Chromatin Condensation and Enucleation in Red Blood Cells:\u00a0 an Open Question. <em>Dev Cell 36:<\/em>\u00a0 481-482.<\/span><\/p>\n<p><span style=\"color: #333333\">Barminko, J., Reinholt, B.M., Emmanuelli, A., Lejeune, A.N. and <strong>Baron, M.H.<\/strong>\u00a0 (2018) Activation of the vitamin D receptor transcription factor stimulates the growth of definitive erythroid progenitors.\u00a0 <em>Blood Advances<\/em> 2: 1207-1219.\u00a0 PMCID: PMC599893.<\/span><\/p>\n<p><span style=\"color: #333333\">Fu, J., Wei, C., Zhang, W., Schlondorff, D., Wu, J., Cai, M., He, W., <strong>Baron, M. H.,<\/strong> Chuang, P. Y., Liu, Z., He, J. C., Lee, K. (2018) Gene expression profiles of glomerular endothelial cells support their role in the glomerulopathy of diabetic mice. <em>Kidney International<\/em> 94(2): 326-345.\u00a0 PMCID: <a style=\"color: #333333\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6054896\/\">PMC6054896<\/a>.<\/span><\/p>\n<p><span style=\"color: #333333\">Ebefors, K., Wiener, R.J., Yu, L., Azeloglu, E.U., Yi, Z., Jia, F., Zhang, W., <strong>Baron, M.H.<\/strong>, He, J.C., Haraldsson, B., and Daehn, I. (2019) Endothelin receptor-A mediates degradation of glomerular endothelial surface layer via pathologic crosstalk between activated podocytes and glomerular endothelial cells. <em>Kidney International<\/em> 96(4):957-970. PMCID: <a style=\"color: #333333\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmc7200072\/\">PMC7200072. <\/a><\/span><\/p>\n<p><span style=\"color: #333333\">Barminko, J., Vacaru, A., and <strong>Baron, M.H<\/strong>. (2020) Generation of Transgenic Fluorescent Reporter Lines for Studying Hematopoietic Development in the Mouse. <em>Methods in Molecular Biology<\/em>, in press.<\/span><\/p>\n<p>\u00a0<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text admin_label=&#8221;Contact Us&#8221; _builder_version=&#8221;3.19.10&#8243; saved_tabs=&#8221;all&#8221;]<\/p>\n<p><strong>Margaret Baron Laboratory<\/strong><\/p>\n<p>Lab:<br \/>Annenberg 24-68<br \/>212-241-0838<br \/>Admin Phone: 212-241-6287<br \/>Fax: 646-537-8698<br \/>Email:\u00a0<a href=\"mailto:margaret.baron@mssm.edu\">margaret.baron@mssm.edu<\/a><\/p>\n<p>Office:<br \/>Annenberg 24-04E<br \/>212-241-0825<\/p>\n<p>Icahn School of Medicine at Mount Sinai<br \/>1468 Madison Avenue, AB24-68<br \/>Box 1079<br \/>New York, NY 10029<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p><div class=\"et_pb_row et_pb_row_0 et_pb_row_empty\">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div> Baron, M.H., Evans, D.R., and W.N. Lipscomb (1979) The Location and Local Environment of the Active Sites of Aspartate Transcarbamylase of Escherichia coli. J. Biol. Chem. 254: 10686-10693.Das Gupta, A., Baron, M.H., and D. Baltimore (1979) Poliovirus replicase: A soluble enzyme able to initiate copying of poliovirus RNA. Proc. Natl. Acad. Sci. U.S.A. 76: [&hellip;]<\/p>\n","protected":false},"author":172,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p><a href=\"https:\/\/labs.icahn.mssm.edu\/margarethbaron-lab\/wp-content\/uploads\/sites\/186\/2016\/07\/BaronLab-Publications-Fig1.jpg\"><img class=\"size-full wp-image-86 aligncenter\" src=\"https:\/\/labs.icahn.mssm.edu\/margarethbaron-lab\/wp-content\/uploads\/sites\/186\/2016\/07\/BaronLab-Publications-Fig1.jpg\" alt=\"BaronLab-Publications-Fig1\" width=\"200\" height=\"260\" \/><\/a><br \/>Baron, M.H., Evans, D.R., and W.N. Lipscomb (1979) The Location and Local Environment of the Active Sites of Aspartate Transcarbamylase of Escherichia coli. J. Biol. Chem. 254: 10686-10693.<\/p><p>Das Gupta, A., Baron, M.H., and D. Baltimore (1979) Poliovirus replicase: A soluble enzyme able to initiate copying of poliovirus RNA. Proc. Natl. Acad. Sci. U.S.A. 76: 2679-2683.<\/p><p>Baron, M.H. and D. Baltimore (1982) Antibodies Against the Chemically Synthesized Genome-Linked Protein of Poliovirus React with Native Virus-Specific Proteins. Cell 28: 395-404.<\/p><p>Baron, M.H. and D. Baltimore (1982) Purification and Properties of a Host Cell Protein Required for Poliovirus Replication in Vitro. J.Biol. Chem. 257: 12351-12358.<br \/>Baron, M.H. and D. Baltimore (1982) In Vitro Copying of Viral Positive Strand RNA by Poliovirus Replicase: Characterization of the Reaction and its Products. J. Biol. Chem. 257: 12359-12366.<\/p><p>Baron, M.H. and D. Baltimore (1982) Antibodies Against a Synthetic Peptide of Poliovirus Replicase Protein: Reaction with Native, Virus-Encoded Proteins and Inhibition of Virus-Specific Polymerase Activities in Vitro J. Virol. 43: 969-978.<\/p><p>Baron, M.H. and D. Baltimore (1982) Anti-VPg Antibody Inhibition of the Poliovirus Replicase Reaction and Production of Covalent Complexes of VPg-Related Polypeptides and Newly-Made RNA. Cell 30: 745-752.<\/p><p>Baron, M.H. and T. Maniatis (1986) Rapid Reprogramming of Globin Gene Expression in Transient Heterokaryons. Cell 46: 591-602.<\/p><p>Baron, M.H. and T. Maniatis (1987) Stage-Specific Reprogramming of Globin Gene Expression. Progr. Clin. Biol. Res. 251: 271-284.<\/p><p>Baron, M.H. and T. Maniatis (1987) Reprogramming of Globin Gene Expression in Interspecific Heterokaryons. In Molecular Approaches to Developmental Biology, Alan R. Liss, Inc.,pp. 469-476.<\/p><p>Baron, M.H. and T. Maniatis (1991) Regulated Expression of Human a- and b-Globin Genes in Transient Heterokaryons. Mol. Cell. Biol. 11: 1239-1247.<\/p><p>Trepicchio, W.L., Dyer, M.A. and M.H. Baron (1993) Developmental regulation of the human embryonic b-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elements, Mol. Cell. Biol. 13 : 7457-7468.<\/p><p>Baron, M.H. (1993) Reversibility of the Differentiated State in Somatic Cells. Current Opinion Cell Biol. 5: 1050-1056, Current Biology Ltd., London.<\/p><p>Baron, M.H. and S.M. Farrington (1994) Positive regulators of the lineage-specific transcription factor GATA-1 in differentiating erythroid cells, Mol. Cell. Biol.14: 3108-3114.<\/p><p>Trepicchio, W.L., Dyer, M.A., and M.H. Baron (1994) A novel developmental regulatory motif required for stage-specific activation of the e-globin gene and nuclear factor binding in embryonic erythroid cells, Mol. Cell. Biol. 14: 3763-3771.<\/p><p>Trepicchio, W.L., Dyer, M.A., Hardison, R.C., and M.H. Baron (1994) Upstream regulatory region of the human embryonic b-like globin gene, e, DNA Sequence 4: 409-412.<\/p><p>Baron, M.H. (1994) Embryonic Erythroid Differentiation and Development. Symp. European School of Molec. Med. (Signal Transduction in Differentiation and Trans-Differentiation), Brescia, Italy.<\/p><p>Lister, J., Forrester, W.C., and M.H. Baron (1995) Inhibition of an erythroid differentiation switch by the helix-loop-helix protein, Id1. J. Biol. Chem. 270 : 17939-17946.<\/p><p>Dyer, M.A., W.L. Trepicchio, M. Belaoussoff, S.M. Farrington, and M.H. Baron (1995) Molecular Mechanisms of Embryonic b-Like Globin Gene Regulation During Mammalian Development. Hemoglobin Switching, vol. 1, Intercept Ltd., pp. 135-151.<\/p><p>Dyer, M.A., Naidoo, R., Hayes, P.J., Larson, C.J., Verdine, G.L. and M.H. Baron (1996) A DNA bending protein interacts with an essential upstream regulatory element of the human embryonic \uf062-like globin gene. Mol. Cell. Biol. 16: 829-838.<\/p><p>Baron, M.H. (1996) Developmental Regulation of the Vertebrate Globin Multigene Family. Gene Expression 6: 129-137.<\/p><p>Farrington, S.M., Belaoussoff, M. and M.H. Baron (1997) Winged helix, hedgehog, and Bmp genes are differentially restricted to functionally distinct tissue layers within the murine embryonic yolk sac. Mech. Develop. 62: 197-211.<\/p><p>Baron, M.H. (1997) Transcriptional control of globin gene expression during vertebrate development. Biochim. Biophys. Acta 1351: 51-72.<\/p><p>Lister, J. and M.H. Baron (1998) Induction of basic-helix-loop-helix protein-containing complexes during erythroid differentiation. Gene Expression 7: 25-38.<\/p><p>Dyer, M.A., Hayes, P.J., and M.H. Baron (1998) The HMG domain protein SSRP1\/PREIIBF is involved in activation of the human embryonic b-like globin gene. Mol. Cell Biol. 18: 2617- 2628.<\/p><p>Belaoussoff, M., Farrington, S.M. and M.H. Baron (1998) Hematopoietic Induction and Respecification of A-P Identity by Visceral Endoderm Signaling in the Mouse Embryo. Development 125: 5009- 5018.<\/p><p>Spencer, J. A., Baron, M. H., and Olson, E. N. (1999) Cooperative Transcriptional Activation by\u00a0Serum Response Factor and the High Mobility Group Protein SSRP1. J. Biol. Chem. 274: 15686-15693.<\/p><p>Baron, M.H. (2000) Interaction of endoderm and ectoderm in embryonic hematopoiesis. Exper. Hematol. 28: 129-.<\/p><p>Baron, M.H. (2001) Embryonic Induction of Mammalian Hematopoiesis and Vasculogenesis. In: L. Zon, ed. Hematopoiesis, Chapter 13, New York, Oxford University Press, pp. 160-170.<\/p><p>Dyer, M.A., Farrington, S.M., Mohn, D., Munday, J., and M.H. Baron (2001) Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. Development 128: 1717-1730.<\/p><p>Baron, M.H. (2001) Induction of Embryonic Hematopoietic and Endothelial Stem\/Progenitor Cells by Hedgehog-Mediated Signals. Differentiation 69: 175-185.<\/p><p>Baron, M.H. (2001) Molecular Regulation of Embryonic Hematopoiesis and Vascular Development: A Novel Pathway. J. Hematother. Stem Cell Res. (now Stem Cells and Development) 10: 587- 594.<\/p><p>Baron, M.H. and Mitus, A.J. (2002) Chapter 15: Blood Disorders. In: K. Carlson and S.A. Eisenstadt,\u00a0eds. Primary Care of Women, 2nd Ed., St. Louis, Mosby-Year Book, Inc., pp. 142-150.<\/p><p>Sahr, K., Dias, D., Sanchez, R., Chen, D., Chen, S., Gudas, L. and M.H. Baron (2002). Structure, upstream promoter region, and functional domains of a mouse and human Mix paired-like homeobox gene. Gene 291: 135-147.<\/p><p>Baron, M. H. (2002) Activation of Hematopoiesis and Vasculogenesis in the Mouse Embryo: Induction and Reprogramming of Ectodermal Cell Fate by Signals from Primitive Endoderm. In: Eaton, G.R., Wiley, D.C., and Jardetsky, O., eds. Structures and Mechanisms: From Ashes to Enzymes (ACS Symposium Series), Vol. 827 (Washington, DC, American Chemical Society), pp. 294-308.<\/p><p>Jones, E.A.V., D. Crotty, P. Kulesa, C.W. Waters, M.H. Baron, S.E. Fraser, M.E. Dickinson (2002) Dynamic In Vivo Imaging of Post-Implantation Mammalian Embryos Using Whole Embryo Culture. Genesis 34: 228-235.<\/p><p>Mohn, D., Chen, S., Dias, D., Weinstein, D., Dyer, M.A., Sahr, K., Ducker, C.E., Zahradka, K.E., Keller, G., Zaret, K.S., Gudas, L. and M.H. Baron (2003) The mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Developmental Dynamics 226: 446-459.<\/p><p>Baron, M.H. (2003) Embryonic Origins of Mammalian Hematopoiesis. Experimental Hematology, 31: 1160-1169.<\/p><p>Baron, M.H. (2004) Hemangioblasts in Adults? [\"Inside Blood,\" invited commentary] Blood 103: 1.<\/p><p>Jones, E.A.V., Baron, M.H., Fraser, S.E., and Dickinson, M.E. (2004) Measuring Hemodynamic Changes During Mammalian Development. Amer. J. Physiol. 287: H1561-H1569.<\/p><p>Snyder, A., Fraser, S.T., and Baron, M.H. (2004) Bone Morphogenetic Proteins in Vertebrate Hematopoietic Development. J. Cellular Biochem. 93: 224-232. Cover article.<\/p><p>Baron, M.H. (ed.) (2005) Developmental Regulation of Hematopoiesis: Methods and Protocols. Methods in Molecular Medicine series, New York, Humana Press.<br \/>\u2022 This publication was highlighted in a review by de Bruijn, M. (2005) Developmental hematopoiesis from fly to human. Development 132: 5128-5130.<\/p><p>Jones, E.A.V., Crotty, D., Baron, M.H., Fraser, S.E. and Dickinson, M.E. (2005) Dynamic In Vivo Imaging of Mammalian Hemato-Vascular Development Using Whole Embryo Culture. Developmental Regulation of Hematopoiesis: Methods and Protocols, ed. Baron, M.H., Methods in Molecular Medicine series, New York, Humana Press, pp. 381-393.<\/p><p>Baron, M.H. and Mohn, D. (2005) Mouse Embryonic Explant Culture System for Analysis of Hematopoietic and Vascular Development. In Developmental Regulation of Hematopoiesis: Methods and Protocols, ed. Baron, M.H., Methods in Molecular Medicine series, New York, Humana Press, pp. 231-256.<\/p><p>Baron, M.H. and Fraser, S.T. (2005) The Specification of Early Hematopoiesis in the Mammal. I. Lemischka, ed. Current Opinion in Hematology 12: 217-221.<\/p><p>Fraser, S.T., Hadjantonakis, K., Willey, S., Sahr, K.E., Kelly, O.G., Jones, E.A.V., Dickinson, M.E., and Baron, M.H. (2005) Using a Histone Yellow Fluorescent Protein Fusion for Tagging and Tracking Endothelial Cells in ES Cells and Mice. Genesis 42: 162-171.<\/p><p>Baron, M.H. (2005) Early Patterning of the Mouse Embryo: Implications for Hematopoietic Commitment and Differentiation. Experimental Hematology 33: 1015-1020.<\/p><p>Willey, S., Ayuso-Sacido, A., Zhang, H., Fraser, S.T., Adlam, M.A., Sahr, K., Kyba, M., Daley, G.Q., Keller, G., and Baron, M.H. (2006) Acceleration of Mesoderm Development and Expansion of Hematopoietic Progenitors in Differentiating ES Cells by the Mouse Mix-Like Homeodomain Transcription Factor. Blood 107: 3122-3130. First Edition Paper, January 10, 2006; DOI 10.1182\/blood-2005-10-4120. PMCID: PMC1784910<\/p><p>Kwon, G., Fraser, S.T., Eakin, G., Mangano, M., Isern, J., Sahr, K.E., Hadjantonakis, A.-K., and Baron, M.H. (2006) Tg(Afp-GFP) Expression Marks Primitive and Definitive Endoderm Lineages during Mouse Development. Developmental Dynamics 235: 2549-2558. Epub ahead of press.<\/p><p>Fraser, S.T., Isern, J. and Baron, M.H. (2007) Maturation and enucleation of primitive erythroblasts is accompanied by changes in cell surface antigen expression patterns during mouse embryogenesis. Blood 109: 343-352. First Edition Paper, August 29, 2006; DOI 10.1182\/blood- 2006-03-006569.<\/p><p>Haremaki, T., Fraser, S.T., Kuo, Y.-M., Baron, M.H., and Weinstein, D.C. (2007) Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc. Natl. Acad. Sci. U.S.A. 104: 12029-12034. Early Edition, 10.1073_pnas0701413104.<\/p><p>Durand, C., Robin, C., Bollerot, K., Baron, M.H., Ottersbach, K., and Dzierzak, E. (2007) Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells, Proc. Natl. Acad. Sci. U.S.A. 104: 20838-20843.<br \/>Baron, M.H. (2008) The wanderings of hematopoietic stem cells. Blood 111: 3307-3308 [\"Inside Blood,\" invited commentary].<\/p><p>Isern, J., Fraser, S.T., He, Z. and Baron, M.H. (2008) The fetal liver is a niche for maturation of primitive erythroid cells. Proc. Natl. Acad. Sci. U.S.A. 105: 6662-6667. [Also see \"This Week in PNAS\/In This Issue\"]<\/p><p>Larina, I.V., Shen, W., Kelly, O.G., Hadjantonakis, A.-K., Baron, M.H., and Dickinson, M.E. (2009) A membrane associated mCherry fluorescent reporter line for studying vascular remodeling and cardiac function during murine embryonic development. The Anatomical Record 292: 333-3341.<\/p><p>Fraser, S.T. and Baron, M.H. (2009) Embryonic fates for extraembryonic lineages: new perspectives. J. Cellular Biochem., 107: 586-591.<\/p><p>Zhang, H., Fraser, S.T., Papazoglu, C., Hoatlin, M.E., and Baron, M.H. (2009) The Mouse Mesendoderm Gene Goosecoid is a Transcriptional Target of the Mixl1 Homeodomain Protein in Differentiating Embryonic Stem Cells. Stem Cells 27: 2884-2895. [Epub ahead of print] PMID: 19711456.<\/p><p>Isern, J., Fraser, S.T., He, Z. and Baron, M.H. (2010) Developmental niches for embryonic erythroid cells. Blood Cells, Molecules and Diseases 44: 207-208, DOI 10.1016\/j.bcmd.2010.02.008. PMCID: PMC2846976.<\/p><p>Fraser, S.T., Isern, J. and Baron, M.H. (2010) Use of transgenic fluorescent reporter mouse lines to monitor hematopoietic and erythroid development during embryogenesis. Methods in Enzymology, P. Wassarman and P. Soriano, eds. [invited chapter], vol. 476, pp. 403-427. PMID: 20691878.<\/p><p>Isern, J., Fraser, S.T., He, Z., Zhang, H., and Baron, M.H. (2010) Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf. Blood 116: 3972-3980. DOI 10.1182\/blood-2010-04-281196. PMID:20720183. Cover article.<\/p><p>Isern, J., He, Z., Fraser, S.T., Nowotschin, S., Ferrer-Vaquer, A., Moore, R., Hadjantonakis, A.-K., Schulz, V., Tuck, D., Gallagher, P.G., and Baron, M.H. (2011) Single Lineage Transcriptome Analysis Reveals Key Regulatory Pathways in Primitive Erythroid Progenitors in the Mouse Embryo, Blood 117: 4924-4934, First Edition Paper, prepublished online January 24, 2011;DOI 10.1182\/blood-2010-10-313676. PMID: 21263157. Cover article.<br \/>\u2022 This article was highlighted in the commentary Inside Blood, Mullner, E. Erythropoiesis: early, not primitive. Blood 117: 4685-4686.<\/p><p>Artus, J., Douvaras, P., Piliszek, A., Isern, J., Baron, M.H. and Hadjantonakis, A.-K. BMP4 signalling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity, Developmental Biology 361: 245-262. PMID: 22051107.<\/p><p>Baron, M.H., Isern, J. and Fraser, S. (2012) The embryonic origins of erythropoiesis in mammals. Blood 119: 4828-4837 [Invited review]. PMID: 22337720<\/p><p>Baron, M.H. (2013) Early Embryonic Erythropoiesis \u2026 Not so Primitive After All. Stem Cells 31: 849-856, doi: 10.1002\/stem.1342. [Epub ahead of print] PMCID: PMC3637392 [Invited review].<\/p><p>Baron, M.H., Vacaru, A., and Nieves, J. (2013) Erythroid Development in the Mammalian Embryo. Blood Cells, Molecules and Diseases 51(4): 213-219, ed. J. Palis, [Invited review].<\/p><p>Vacaru, A., Isern, J., Fraser, S.T., and Baron, M.H. (2013) Analysis of primitive erythroid cell proliferation and enucleation using a cyan fluorescent reporter in transgenic mice. Genesis 51(11): 751-62. doi: 10.1002\/dvg.22420. Epub 2013 Aug 30. [Epub ahead of print] PMID: 23913596. Cover article.<\/p><p>Zhang, H., Nieves, J.L., Fraser, S.T., Isern, J., Douvaras, P., Papatsenko, D., D'Souza, S., Lemischka, I.R., Dyer, M.A., and Baron, M.H. (2013) Expression of Podocalyxin separates the hematopoietic and vascular potentials of mouse ES cell-derived mesoderm. Stem Cells Cells 32(1): 191-203, DOI: 10.1002\/stem.1536 [Epub ahead of print]<\/p><p>Baron, M.H. (2013) The TRIMming on an erythroid receptor complex. Blood 122: 3701-3702 [\"Inside Blood,\" invited commentary].<\/p><p>Pulina, M.V., Sahr, K.E., Baron, M.H.*, and Hadjantonakis, A.-K.* (2014) A conditional mutant allele for analysis of Mixl1 function in the mouse. Genesis 52: 417-423. * Joint corresponding authors.\u00a0PMID: 24596343<\/p><p>Vacaru, A., Vitale, J., Nieves, J., and Baron, M.H. (2014) Generation of Transgenic Mouse Fluorescent Reporter Lines for Studying Hematopoietic Development. Methods Mol. Biol. 1194: 289-312, S.R. Singh, ed. (New York, Springer and Humana Press). DOI 10.1007\/978-1-4939-1215-5_16 [Invited chapter].<\/p><p>Zhang, X., Camprecios, G., Rimmele, P., Liang, R., Yalcin, S., Mungamuri, S.K., Barminko, J., D'Escamard, V., Baron, M.H., Brugnara, C., Papatsenko, D., Rivella, S., and Ghaffari, S. (2014). FOXO3-mTOR Metabolic Cooperation in the Regulation of Erythroid Cell Maturation and Homeostasis. Am J Hematol. 89(10): 954-963. Prepublished on 2014\/06\/27 as DOI 10.1002\/ajh.23786 PMID:24966026<\/p><p>Fan, Y., Li, X., Fu, J., Harris, R., Lindenmeyer, M., Cohen, C.D., Guillot, N., Baron, M.H., Kyung, L., He, C., Schlondorff, D. and Chuang, P.Y. (2015) BAMBI elimination enhances non-canonical glomerular ERK1\/2 and Smad1\/5 signaling and glomerular dysfunction in diabetic mice. Diabetes, in press.<\/p><p>\u00a0<\/p>","_et_gb_content_width":"","footnotes":""},"class_list":["post-35","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/margaretbaron-lab\/wp-json\/wp\/v2\/pages\/35","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/margaretbaron-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/margaretbaron-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/margaretbaron-lab\/wp-json\/wp\/v2\/users\/172"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/margaretbaron-lab\/wp-json\/wp\/v2\/comments?post=35"}],"version-history":[{"count":11,"href":"https:\/\/labs.icahn.mssm.edu\/margaretbaron-lab\/wp-json\/wp\/v2\/pages\/35\/revisions"}],"predecessor-version":[{"id":146,"href":"https:\/\/labs.icahn.mssm.edu\/margaretbaron-lab\/wp-json\/wp\/v2\/pages\/35\/revisions\/146"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/margaretbaron-lab\/wp-json\/wp\/v2\/media?parent=35"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}