{"id":11,"date":"2015-02-09T16:28:30","date_gmt":"2015-02-09T16:28:30","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/levine-lab\/?page_id=11"},"modified":"2015-02-09T16:28:30","modified_gmt":"2015-02-09T16:28:30","slug":"publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/levinelab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Selected Peer-Reviewed Publications (from over 50 publications)<\/span><\/strong><\/p>\n

1.\u00a0\u00a0\u00a0 Liu XH, Kirschenbaum A, Lu M, Yao S, Dosoretz A, Holland JF, and Levine AC.\u00a0 Prostaglandin E2 induces hypoxia-inducible factor-1a stabilization and nuclear localization in a human prostate cancer cell line.\u00a0 Journal of Biol. Chem. 277:50081-50086, 2002. PMID:12401798<\/a><\/p>\n

2.\u00a0\u00a0 Liu XH, Kirschenbaum A, Yu K, Yao S, and Levine AC.\u00a0 Cyclooxygenase-2 suppresses hypoxia-induced apoptosis via a combination of direct and indirect inhibition of p53 activity in a human prostate cancer cell line.\u00a0 J Biol. Chem, 280:3817-3813, 2005. PMID:15550400<\/a><\/p>\n

3.\u00a0\u00a0 Liu XH, Kirschenbaum A, Yao S, and Levine AC.\u00a0 IL-6 and prostaglandin E2 synergistically enhance osteoclastogenesis through effects on the OPG\/RANKL\/RANK system.\u00a0 Endocrinology 146 (4):1991-1998, 2005.\u00a0 PMID:15618359<\/a><\/p>\n

4. \u00a0\u00a0 Kirschenbaum A, Liu XH, Yao S, Narla G, Friedman SL, Martignetti JA, and Levine AC. \u00a0\u00a0Sex steroids have differential effects on growth and gene expression in primary human prostate epithelial cell cultures derived from the peripheral vs. transition zones. Carcinogenesis 27 (2):216-224, 2006. PMID:16123118<\/a><\/p>\n

5.\u00a0\u00a0 Liu XH, Kirschenbaum A, Yao S, and Levine AC. \u00a0Interactive Effects of Interluekin-6 and Prostaglandin E2 on Osteoclastogenesis via the OPG\/RANKL\/RANK System.\u00a0Ann.N.Y. Acad.Sci 1068:225-233, 2006. PMID:16831922<\/a><\/p>\n

6.\u00a0\u00a0 Liu XH, Kirschenbaum A, Yao S, Aaronson SA, Liu G, and Levine AC.\u00a0 Androgen-induced Wnt signaling activation in preosteoblasts promotes the growth of MDA-PCA-2b human prostate cancer cells.\u00a0 Cancer Research 67 (12):5747-53, 2007.\u00a0 PMID:17575141<\/a><\/p>\n

7.\u00a0\u00a0 Liu XH, Kirschenbaum A, Yao S, Levine AC.\u00a0 Androgens promote preosteoblast differentiation via activation of the canonical Wnt signaling pathway.\u00a0 Ann NY Acad Sci 1116:423-431, 2007. PMID:17646262<\/a><\/p>\n

8.\u00a0\u00a0\u00a0 Chen M, Tanner M, Levine AC, Levina E, Ohouo P, Buttyan R.\u00a0Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.\u00a0 Cell Cycle 8(1):149-157, 2009. PMCID:PMC2633936<\/a><\/p>\n

9.\u00a0\u00a0\u00a0 Xiong S.D., Yu K., Liu X-H, Yin LH, Kirschenbaum A, Yao S, Narla G, DiFeo A, Wu JB, Yuan Y, Ho S-M, Lam YW and Levine A.C.\u00a0 Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells. \u00a0Int. J. Cancer 125:774-782, 2009. PMID:19384952<\/a><\/p>\n

10.\u00a0\u00a0 Liu X-H, Kirschenbaum A, Weinstein BM, Zaidi M, Yao S, and Levine AC.\u00a0 Prostaglandin E2 modulates components of the Wnt signaling system in bone and prostate cancer cells.\u00a0 Biochem and Biophys Res Comm. 394(3):715-720, 2010 PMID:20227393<\/a><\/p>\n

11.\u00a0\u00a0\u00a0Zaidi M, Li S, Robinson LJ, Tourkova IL, Liu L, Wang Y, Ling-Ling Z, Li J, Peng Y, Yang G, Sun H, Levine AC, Iqbal J, Yaroslvskiy BB, Isles C, Blair HC.\u00a0 ACTH protects against glucocorticoid-induced osteonecrosis of bone.\u00a0 PNAS\u00a0 May 11:107(19):8782-8787, 2010. PMCID:PMC288931<\/a>6<\/p>\n

12.\u00a0\u00a0\u00a0Yang W. and Levine AC. \u201cAndrogens and Prostate Cancer Bone Metastases: Effects on Both the Seed and the Soil\u201d.\u00a0 In \u201cHormones and Cancer: Breast and Prostate\u201d,<\/em> Elsevier Press, in Special Edition Endocrine Clinics of North America<\/em>, Sep;40(3):643-53, 2011\u00a0 PMID:21889726<\/a><\/p>\n

13.\u00a0\u00a0\u00a0Kirschenbaum A, Liu X-H, Yao S, Levine AC.\u00a0 Prostatic acid phosphatase is expressed in human prostate cancer bone metastases and promotes osteoblast differentiation.\u00a0Ann.N.Y. Acad. Medicine, 1237:64-70, 2011. PMID:22082367<\/a><\/p>\n

14.\u00a0\u00a0\u00a0Cannata DH, Kirschenbaum A, Levine AC\u00a0 Androgen deprivation therapy as primary treatment for prostate cancer.\u00a0 J. Clin. Endocrinol. Metab. 97(2):360-365, 2012. PMID:22162475<\/a><\/p>\n

15.\u00a0 \u00a0Liu XH, Yong W, Yao S, Levine AC, Kirschenbaum A, Collier L, Bauman WA, Cardozo, CP. Androgens Upregulate Transcription of the Notch Inhibitor Numb in C2C12 Myoblasts via Wnt\/beta-catenin Signaling to Tcf Elements in the Numb Promoter. J Biol Chem. 2013 Jun 21;288(25):17990-8. PMID 23649620<\/a><\/p>\n

16.\u00a0 Hatami R, Sieuwerts AM, Izadmehr S, Yao Z, Qiao RF, Papa L, Look MP, Smid M, Ohlssen J, Levine AC, Germain D, Burstein D, Kirschenbaum A, DiFeo A, Foekens JA, Narla G.\u00a0KLF6-SV1 drives breast cancer metastasis and is associated with poor survival.\u00a0Sci Transl Med. 2013 Jan 23;5(169):169ra12.\u00a0PMID:\u00a023345610<\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Selected Peer-Reviewed Publications (from over 50 publications) 1.\u00a0\u00a0\u00a0 Liu XH, Kirschenbaum A, Lu M, Yao S, Dosoretz A, Holland JF, and Levine AC.\u00a0 Prostaglandin E2 induces hypoxia-inducible factor-1a stabilization and nuclear localization in a human prostate cancer cell line.\u00a0 Journal of Biol. Chem. 277:50081-50086, 2002. PMID:12401798 2.\u00a0\u00a0 Liu XH, Kirschenbaum A, Yu K, Yao S, […]<\/p>\n","protected":false},"author":50,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-11","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/levinelab\/wp-json\/wp\/v2\/pages\/11","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/levinelab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/levinelab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/levinelab\/wp-json\/wp\/v2\/users\/50"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/levinelab\/wp-json\/wp\/v2\/comments?post=11"}],"version-history":[{"count":0,"href":"https:\/\/labs.icahn.mssm.edu\/levinelab\/wp-json\/wp\/v2\/pages\/11\/revisions"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/levinelab\/wp-json\/wp\/v2\/media?parent=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}