{"id":2271,"date":"2019-12-04T20:24:29","date_gmt":"2019-12-04T20:24:29","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/lautenberglab-beta\/?page_id=2271"},"modified":"2020-05-11T19:25:18","modified_gmt":"2020-05-11T19:25:18","slug":"trace-metals","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/trace-metals\/","title":{"rendered":"Trace Metals"},"content":{"rendered":"<p>[et_pb_section bb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; specialty=&#8221;off&#8221; next_background_color=&#8221;#000000&#8243; _builder_version=&#8221;3.19.10&#8243; disabled=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221;][et_pb_fullwidth_image _builder_version=&#8221;3.19.10&#8243; src=&#8221;https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-content\/uploads\/sites\/345\/2020\/02\/L-elemental.jpg&#8221; \/][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; specialty=&#8221;off&#8221; _builder_version=&#8221;3.19.10&#8243; next_background_color=&#8221;#000000&#8243; prev_background_color=&#8221;#000000&#8243; custom_margin=&#8221;||3em|&#8221;][et_pb_row _builder_version=&#8221;3.19.10&#8243; make_fullwidth=&#8221;on&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_image admin_label=&#8221;Section Logo&#8221; _builder_version=&#8221;3.19.10&#8243; src=&#8221;https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-content\/uploads\/sites\/345\/2020\/02\/Trace-Metals.jpg&#8221; align=&#8221;center&#8221; max_width=&#8221;12%&#8221; module_alignment=&#8221;center&#8221; border_radii=&#8221;on|100px|100px|100px|100px&#8221; \/][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; prev_background_color=&#8221;#000000&#8243; _builder_version=&#8221;3.19.10&#8243; next_background_color=&#8221;#000000&#8243; custom_margin=&#8221;-6em|||&#8221;][et_pb_row _builder_version=&#8221;3.19.10&#8243; make_fullwidth=&#8221;on&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_text _builder_version=&#8221;3.19.10&#8243;]<\/p>\n<div class=\"et_pb_column et_pb_column_4_4 et_pb_column_0 et_pb_css_mix_blend_mode_passthrough et-last-child\">\n<div class=\"et_pb_module et_pb_text et_pb_text_0 et_pb_bg_layout_light et_pb_text_align_left\">\n<div class=\"et_pb_text_inner\">\n<h2>Trace Metals<\/h2>\n<p>At least 19 elements on the periodic table are essential for human health, though these exist in a delicate balance that can be easily disrupted by disease. Additionally, a range of toxic metals are present in our environment that accumulate in the body and cause long-term health effects, even at incredibly low levels. The primary goal of our Metals Division is to accurately measure a range of metals in biological samples at the lowest levels possible. Using cutting edge technology, we can detect trace levels of the essential elements that include iron, copper, and zinc, as well as toxic heavy metal pollutants like lead, mercury and cadmium. Our overarching goal is to develop and maintain a state-of-the-art facility that applies the best technology available to study how metal exposures contribute to health and disease.<\/p>\n<h3>Analytical Methods:<\/h3>\n<p>Analytical methods for <em>high-throughput<\/em> analyses uses technology including inductively coupled plasma-mass spectrometry, and high-energy argon plasma burning hotter than the surface of the sun to break down samples into their basic atomic components, including metals. We also use a direct mercury analyzer, which is specially designed to measure mercury at the lowest levels possible.<\/p>\n<table border=\"1\" width=\"93%\" cellspacing=\"0\" cellpadding=\"0\">\n<thead>\n<tr>\n<td valign=\"top\" width=\"29%\">Analyte<\/td>\n<td valign=\"top\" width=\"32%\">Matrix<\/td>\n<td valign=\"top\" width=\"38%\">Assay method<\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td valign=\"top\" width=\"29%\"><em>Metals<\/em> Aluminum (Al), Arsenic (As), Cadmium (Cd), Chromium (Cr), Copper (Cu), Iron (Fe), Lead (Pb), Manganese (Mn), Mercury (Hg), Nickel (Ni), Platinum (Pt), Selenium (Se), Vanadium (V), Zinc (Zn) Other metals as requested<\/td>\n<td valign=\"top\" width=\"32%\"><em>Fluids<\/em> Blood, urine, serum, plasma, milk, semen, umbilical cord blood, nasal lavage, lung lavage <em>Soft tissue<\/em> Placenta, umbilical cord, kidney <em>Hard tissue<\/em> Teeth, toenails, fingernails, bone, hair<\/td>\n<td valign=\"top\" width=\"38%\">ICP-MS (solutions, digests), Direct mercury analyzer (Hg)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>\u00a0<\/h3>\n<h3>Key Researchers:<\/h3>\n<p><a href=\"http:\/\/icahn.mssm.edu\/profiles\/chitra-amarasiriwardena\"><strong>Chitra Amarasiriwardena, PhD<\/strong><\/a><\/p>\n<p><a href=\"http:\/\/icahn.mssm.edu\/profiles\/christine-austin\"><strong>Christine Austin, PhD<\/strong><\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section bb_built=&#8221;1&#8243; prev_background_color=&#8221;#000000&#8243; _builder_version=&#8221;3.19.10&#8243; disabled=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221;][et_pb_row _builder_version=&#8221;3.19.10&#8243; make_fullwidth=&#8221;on&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_text _builder_version=&#8221;3.19.10&#8243;]<\/p>\n<div class=\"et_pb_column et_pb_column_4_4 et_pb_column_0 et_pb_css_mix_blend_mode_passthrough et-last-child\">\n<div class=\"et_pb_module et_pb_text et_pb_text_0 et_pb_bg_layout_light et_pb_text_align_left\">\n<div class=\"et_pb_text_inner\">\n<p>At least 19 elements on the periodic table are essential for human health, though these exist in a delicate balance that can be easily disrupted by disease. Additionally, a range of toxic metals are present in our environment that accumulate in the body and cause long-term health effects, even at incredibly low levels. The primary goal of our Metals Division is to accurately measure a range of metals in biological samples at the lowest levels possible. Using cutting edge technology, we can detect trace levels of the essential elements that include iron, copper, and zinc, as well as toxic heavy metal pollutants like lead, mercury and cadmium. Our overarching goal is to develop and maintain a state-of-the-art facility that applies the best technology available to study how metal exposures contribute to health and disease.<\/p>\n<h2>Analytical Methods:<\/h2>\n<p>Analytical methods for <em>high-throughput<\/em> analyses uses technology including inductively coupled plasma-mass spectrometry, and high-energy argon plasma burning hotter than the surface of the sun to break down samples into their basic atomic components, including metals. We also use a direct mercury analyzer, which is specially designed to measure mercury at the lowest levels possible.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;3.19.10&#8243; make_fullwidth=&#8221;on&#8221; custom_margin=&#8221;-5em||-5em|&#8221;][et_pb_column type=&#8221;1_3&#8243;][et_pb_text _builder_version=&#8221;3.19.10&#8243;]<\/p>\n<div class=\"et_pb_column et_pb_column_4_4 et_pb_column_0 et_pb_css_mix_blend_mode_passthrough et-last-child\">\n<div class=\"et_pb_module et_pb_text et_pb_text_0 et_pb_bg_layout_light et_pb_text_align_left\">\n<div class=\"et_pb_text_inner\">\n<p>&nbsp;<\/p>\n<table border=\"1\" width=\"93%\" cellspacing=\"0\" cellpadding=\"0\">\n<thead>\n<tr>\n<td valign=\"top\" width=\"29%\">Analyte<\/td>\n<td valign=\"top\" width=\"32%\">Matrix<\/td>\n<td valign=\"top\" width=\"38%\">Assay method<\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td valign=\"top\" width=\"29%\"><em>Metals<\/em> Aluminum (Al), Arsenic (As), Cadmium (Cd), Chromium (Cr), Copper (Cu), Iron (Fe), Lead (Pb), Manganese (Mn), Mercury (Hg), Nickel (Ni), Platinum (Pt), Selenium (Se), Vanadium (V), Zinc (Zn) Other metals as requested<\/td>\n<td valign=\"top\" width=\"32%\"><em>Fluids<\/em> Blood, urine, serum, plasma, milk, semen, umbilical cord blood, nasal lavage, lung lavage <em>Soft tissue<\/em> Placenta, umbilical cord, kidney <em>Hard tissue<\/em> Teeth, toenails, fingernails, bone, hair<\/td>\n<td valign=\"top\" width=\"38%\">ICP-MS (solutions, digests), Direct mercury analyzer (Hg)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text _builder_version=&#8221;3.19.10&#8243;]<\/p>\n<div class=\"et_pb_column et_pb_column_4_4 et_pb_column_0 et_pb_css_mix_blend_mode_passthrough et-last-child\">\n<div class=\"et_pb_module et_pb_text et_pb_text_0 et_pb_bg_layout_light et_pb_text_align_left\">\n<div class=\"et_pb_text_inner\">\n<p>&nbsp;<\/p>\n<table border=\"1\" width=\"93%\" cellspacing=\"0\" cellpadding=\"0\">\n<thead>\n<tr>\n<td valign=\"top\" width=\"29%\">Analyte<\/td>\n<td valign=\"top\" width=\"32%\">Matrix<\/td>\n<td valign=\"top\" width=\"38%\">Assay method<\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td valign=\"top\" width=\"29%\"><em>Metals<\/em> Aluminum (Al), Arsenic (As), Cadmium (Cd), Chromium (Cr), Copper (Cu), Iron (Fe), Lead (Pb), Manganese (Mn), Mercury (Hg), Nickel (Ni), Platinum (Pt), Selenium (Se), Vanadium (V), Zinc (Zn) Other metals as requested<\/td>\n<td valign=\"top\" width=\"32%\"><em>Fluids<\/em> Blood, urine, serum, plasma, milk, semen, umbilical cord blood, nasal lavage, lung lavage <em>Soft tissue<\/em> Placenta, umbilical cord, kidney <em>Hard tissue<\/em> Teeth, toenails, fingernails, bone, hair<\/td>\n<td valign=\"top\" width=\"38%\">ICP-MS (solutions, digests), Direct mercury analyzer (Hg)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243;][et_pb_text _builder_version=&#8221;3.19.10&#8243;]<\/p>\n<div class=\"et_pb_column et_pb_column_4_4 et_pb_column_0 et_pb_css_mix_blend_mode_passthrough et-last-child\">\n<div class=\"et_pb_module et_pb_text et_pb_text_0 et_pb_bg_layout_light et_pb_text_align_left\">\n<div class=\"et_pb_text_inner\">\n<p>&nbsp;<\/p>\n<table border=\"1\" width=\"93%\" cellspacing=\"0\" cellpadding=\"0\">\n<thead>\n<tr>\n<td valign=\"top\" width=\"29%\">Analyte<\/td>\n<td valign=\"top\" width=\"32%\">Matrix<\/td>\n<td valign=\"top\" width=\"38%\">Assay method<\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td valign=\"top\" width=\"29%\"><em>Metals<\/em> Aluminum (Al), Arsenic (As), Cadmium (Cd), Chromium (Cr), Copper (Cu), Iron (Fe), Lead (Pb), Manganese (Mn), Mercury (Hg), Nickel (Ni), Platinum (Pt), Selenium (Se), Vanadium (V), Zinc (Zn) Other metals as requested<\/td>\n<td valign=\"top\" width=\"32%\"><em>Fluids<\/em> Blood, urine, serum, plasma, milk, semen, umbilical cord blood, nasal lavage, lung lavage <em>Soft tissue<\/em> Placenta, umbilical cord, kidney <em>Hard tissue<\/em> Teeth, toenails, fingernails, bone, hair<\/td>\n<td valign=\"top\" width=\"38%\">ICP-MS (solutions, digests), Direct mercury analyzer (Hg)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;3.19.10&#8243; make_fullwidth=&#8221;on&#8221;][et_pb_column type=&#8221;4_4&#8243;][et_pb_text _builder_version=&#8221;3.19.10&#8243;]<\/p>\n<div class=\"et_pb_column et_pb_column_4_4 et_pb_column_0 et_pb_css_mix_blend_mode_passthrough et-last-child\">\n<div class=\"et_pb_module et_pb_text et_pb_text_0 et_pb_bg_layout_light et_pb_text_align_left\">\n<div class=\"et_pb_text_inner\">\n<p>At least 19 elements on the periodic table are essential for human health, though these exist in a delicate balance that can be easily disrupted by disease. Additionally, a range of toxic metals are present in our environment that accumulate in the body and cause long-term health effects, even at incredibly low levels. The primary goal of our Metals Division is to accurately measure a range of metals in biological samples at the lowest levels possible. Using cutting edge technology, we can detect trace levels of the essential elements that include iron, copper, and zinc, as well as toxic heavy metal pollutants like lead, mercury and cadmium. Our overarching goal is to develop and maintain a state-of-the-art facility that applies the best technology available to study how metal exposures contribute to health and disease.<\/p>\n<h2>Analytical Methods:<\/h2>\n<p>Analytical methods for <em>high-throughput<\/em> analyses uses technology including inductively coupled plasma-mass spectrometry, and high-energy argon plasma burning hotter than the surface of the sun to break down samples into their basic atomic components, including metals. We also use a direct mercury analyzer, which is specially designed to measure mercury at the lowest levels possible.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Trace MetalsAt least 19 elements on the periodic table are essential for human health, though these exist in a delicate balance that can be easily disrupted by disease. Additionally, a range of toxic metals are present in our environment that accumulate in the body and cause long-term health effects, even at incredibly low levels. The [&hellip;]<\/p>\n","protected":false},"author":274,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-2271","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-json\/wp\/v2\/pages\/2271","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-json\/wp\/v2\/users\/274"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-json\/wp\/v2\/comments?post=2271"}],"version-history":[{"count":15,"href":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-json\/wp\/v2\/pages\/2271\/revisions"}],"predecessor-version":[{"id":2833,"href":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-json\/wp\/v2\/pages\/2271\/revisions\/2833"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-json\/wp\/v2\/media?parent=2271"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}