{"id":2108,"date":"2019-12-04T20:23:33","date_gmt":"2019-12-04T20:23:33","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/lautenberglab-beta\/?page_id=2108"},"modified":"2025-02-19T20:58:53","modified_gmt":"2025-02-19T20:58:53","slug":"d-home","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/lautenberglab\/","title":{"rendered":"Home"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;3.22&#8243; background_image=&#8221;https:\/\/www.youtube.com\/watch?v=1IkY0_qONRk&#8221;][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;3.22&#8243; background_image=&#8221;https:\/\/www.youtube.com\/watch?v=1IkY0_qONRk&#8221; background_video_mp4=&#8221;https:\/\/neuroscience.mssm.edu\/lautenberg\/lautenberg_broll.mp4&#8243; disabled=&#8221;on&#8221;][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;3.22&#8243; disabled=&#8221;on&#8221;][et_pb_row column_structure=&#8221;1_4,1_4,1_4,1_4&#8243; module_class=&#8221; et_pb_row_fullwidth&#8221; _builder_version=&#8221;3.25&#8243; width=&#8221;89%&#8221; width_tablet=&#8221;80%&#8221; width_phone=&#8221;&#8221; width_last_edited=&#8221;on|desktop&#8221; max_width=&#8221;89%&#8221; max_width_tablet=&#8221;80%&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|desktop&#8221; make_fullwidth=&#8221;on&#8221;][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_number_counter number=&#8221;11,526&#8243; percent_sign=&#8221;off&#8221; _builder_version=&#8221;3.19.10&#8243; number_font=&#8221;|700|||||||&#8221; number_font_size=&#8221;35&#8243;][\/et_pb_number_counter][et_pb_text _builder_version=&#8221;3.27.4&#8243;]<\/p>\n<p style=\"text-align: center;font-size: 20px\"><strong>Square Feet of Laboratory Space<\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; 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_builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_number_counter number=&#8221;$55 Million&#8221; percent_sign=&#8221;off&#8221; _builder_version=&#8221;3.19.10&#8243; number_font=&#8221;|700|||||||&#8221; number_font_size=&#8221;35&#8243;][\/et_pb_number_counter][et_pb_text _builder_version=&#8221;3.27.4&#8243;]<\/p>\n<p style=\"text-align: center;font-size:20px\"><strong><span class=\"hotkey-layer \">In grants and contracts in 2019<\/span><\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_5,1_5,1_5,1_5,1_5&#8243; disabled_on=&#8221;on|on|on&#8221; module_class=&#8221; et_pb_row_fullwidth&#8221; _builder_version=&#8221;3.25&#8243; width=&#8221;89%&#8221; width_tablet=&#8221;80%&#8221; width_phone=&#8221;&#8221; width_last_edited=&#8221;on|desktop&#8221; max_width=&#8221;89%&#8221; max_width_tablet=&#8221;80%&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|desktop&#8221; make_fullwidth=&#8221;on&#8221; disabled=&#8221;on&#8221;][et_pb_column type=&#8221;1_5&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_number_counter number=&#8221;11,526&#8243; percent_sign=&#8221;off&#8221; _builder_version=&#8221;3.19.10&#8243; number_font=&#8221;|700|||||||&#8221; number_font_size=&#8221;35&#8243;][\/et_pb_number_counter][et_pb_text _builder_version=&#8221;3.27.4&#8243;]<\/p>\n<p style=\"text-align: center;font-size: 18px\"><strong>Square Feet of Laboratory Space<\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_5&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_number_counter number=&#8221;100+&#8221; percent_sign=&#8221;off&#8221; _builder_version=&#8221;3.19.10&#8243; number_font=&#8221;|700|||||||&#8221; number_font_size=&#8221;35&#8243;][\/et_pb_number_counter][et_pb_text _builder_version=&#8221;3.27.4&#8243;]<\/p>\n<p style=\"text-align: center;font-size:18px\"><strong><span class=\"hotkey-layer \">Samples Analyzed<\/span><\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_5&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_number_counter number=&#8221;16&#8243; percent_sign=&#8221;off&#8221; _builder_version=&#8221;3.19.10&#8243; number_font=&#8221;|700|||||||&#8221; number_font_size=&#8221;35&#8243;][\/et_pb_number_counter][et_pb_text _builder_version=&#8221;3.27.4&#8243;]<\/p>\n<p style=\"text-align: center;font-size:18px\"><strong><span class=\"hotkey-layer \">Specimen Types<\/span><\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_5&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_number_counter number=&#8221;$55 Million&#8221; percent_sign=&#8221;off&#8221; _builder_version=&#8221;3.19.10&#8243; number_font=&#8221;|700|||||||&#8221; number_font_size=&#8221;35&#8243;][\/et_pb_number_counter][et_pb_text _builder_version=&#8221;3.27.4&#8243;]<\/p>\n<p style=\"text-align: center;font-size:18px\"><strong><span class=\"hotkey-layer \">In Grants Awarded to Date<\/span><\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_5&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_number_counter number=&#8221;829&#8243; percent_sign=&#8221;off&#8221; _builder_version=&#8221;3.19.10&#8243; title_font=&#8221;|700|||||||&#8221; number_font_size=&#8221;35&#8243;][\/et_pb_number_counter][et_pb_text _builder_version=&#8221;3.27.4&#8243;]<\/p>\n<p style=\"text-align: center;font-size:18px\"><strong><span class=\"hotkey-layer \">Publications Authored by Lab Faculty<\/span><\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;3.25&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_divider divider_weight=&#8221;0.5&#8243; _builder_version=&#8221;3.19.10&#8243;][\/et_pb_divider][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; module_class=&#8221; et_pb_specialty_fullwidth&#8221; _builder_version=&#8221;3.22&#8243; inner_width=&#8221;89%&#8221; inner_width_tablet=&#8221;80%&#8221; inner_width_phone=&#8221;&#8221; inner_width_last_edited=&#8221;on|desktop&#8221; inner_max_width=&#8221;89%&#8221; inner_max_width_tablet=&#8221;80%&#8221; inner_max_width_phone=&#8221;&#8221; inner_max_width_last_edited=&#8221;on|desktop&#8221; custom_margin=&#8221;||10%|&#8221; make_fullwidth=&#8221;on&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;3.27.4&#8243; text_font=&#8221;Open Sans||||||||&#8221; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;2em&#8221; animation_style=&#8221;fade&#8221;]<\/p>\n<p><strong><span style=\"font-size: 20px\">The\u00a0<a href=\"https:\/\/mountsinaiexposomics.org\/\">Institute for Exposomic Research<\/a>\u00a0is the nucleus of the Icahn School of Medicine at Mount Sinai\u2019s research on environmental exposures\u00a0and their impact on human health.\u00a0<\/span><\/strong><\/p>\n<p>The <strong>Senator Frank R. Lautenberg Environmental Health Sciences Laboratory<\/strong>, co-located with the <strong>Laboratory for Innovation in Exposomic Precision Medicine<\/strong> in the Atran Building, shares an approximately 15,000-square-foot facility with 10,000 square feet of bench space.\u00a0<\/p>\n<p>The <strong>Physiological Assessment of Children\u2019s Environmental Risk (PACER) Laboratory<\/strong>, established in 2012 by Rosalind Wright, MD, MPH, is focused on the assessment of key regulatory biological response systems in pregnant women, infants, and children.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;4&#8243; admin_label=&#8221;Row&#8221; _builder_version=&#8221;3.25&#8243; custom_margin=&#8221;-5.7%|-20%||&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-content\/uploads\/sites\/345\/2019\/11\/measure_human_environment.png&#8221; align=&#8221;right&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;3.23&#8243; custom_margin=&#8221;|-13%||&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;right&#8221; animation_duration=&#8221;1500ms&#8221; animation_delay=&#8221;200ms&#8221; animation_intensity_slide=&#8221;30%&#8221; border_radii=&#8221;on|0px|0px|0px|0px&#8221;][\/et_pb_image][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; module_class=&#8221; et_pb_specialty_fullwidth&#8221; _builder_version=&#8221;3.22&#8243; background_color=&#8221;#efefef&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-content\/uploads\/sites\/345\/2019\/11\/innovative_technologies_background-1.png&#8221; inner_width=&#8221;89%&#8221; inner_width_tablet=&#8221;80%&#8221; inner_width_phone=&#8221;&#8221; inner_width_last_edited=&#8221;on|desktop&#8221; inner_max_width=&#8221;89%&#8221; inner_max_width_tablet=&#8221;80%&#8221; inner_max_width_phone=&#8221;&#8221; inner_max_width_last_edited=&#8221;on|desktop&#8221; custom_margin=&#8221;-5%|||&#8221; make_fullwidth=&#8221;on&#8221; disabled=&#8221;on&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/labs.icahn.mssm.edu\/lautenberglab\/wp-content\/uploads\/sites\/345\/2019\/11\/innovative_technologies.png&#8221; align_tablet=&#8221;center&#8221; align_phone=&#8221;&#8221; align_last_edited=&#8221;on|desktop&#8221; _builder_version=&#8221;3.23&#8243; custom_margin=&#8221;||-15%|-13%&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;left&#8221; animation_intensity_slide=&#8221;30%&#8221; border_radii=&#8221;on|0px|0px|0px|0px&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; specialty_columns=&#8221;3&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_row_inner use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;4&#8243; admin_label=&#8221;Row&#8221; _builder_version=&#8221;3.25&#8243; custom_margin=&#8221;|-20%||&#8221;][et_pb_column_inner saved_specialty_column_type=&#8221;1_2&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;3.27.4&#8243; text_font=&#8221;Open Sans||||||||&#8221; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;2em&#8221; animation_style=&#8221;fade&#8221;]<\/p>\n<p>\n<strong><span style=\"font-size: 20px\">Our lab is equipped with innovative technologies that enable the team to:<\/span><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-size: 18px\">Develop new, groundbreaking analytical methods, which assess chemical exposures and the timing of past chemical exposures. <\/span><\/p>\n<p><span style=\"font-size: 18px\">Expand the scope of research we conduct at Mount Sinai to include areas such as air pollution, metals, organics, chemical mixtures, epigenetics, and the fetal origins of adult diseases. <\/span><\/p>\n<p><span style=\"font-size: 18px\">Advance interdisciplinary research among our faculty, bringing together scientists with different backgrounds and approaches to environmental health and complex diseases. <\/span><\/p>\n<p><span style=\"font-size: 18px\">Create a scientific milieu that fosters innovation, encourages the cross-pollination of ideas, and revolutionizes how children\u2019s environmental health research is conducted.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; specialty=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; module_class=&#8221; et_pb_specialty_fullwidth&#8221; _builder_version=&#8221;3.22&#8243; inner_width=&#8221;89%&#8221; inner_width_tablet=&#8221;80%&#8221; inner_width_phone=&#8221;&#8221; inner_width_last_edited=&#8221;on|desktop&#8221; inner_max_width=&#8221;89%&#8221; inner_max_width_tablet=&#8221;80%&#8221; inner_max_width_phone=&#8221;&#8221; inner_max_width_last_edited=&#8221;on|desktop&#8221; custom_margin=&#8221;10%||10%|&#8221; make_fullwidth=&#8221;on&#8221; disabled=&#8221;on&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;3.25&#8243; custom_padding=&#8221;|||&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;3.27.4&#8243; text_font=&#8221;Open Sans||||||||&#8221; text_font_size=&#8221;16px&#8221; text_line_height=&#8221;2em&#8221; animation_style=&#8221;fade&#8221;]<\/p>\n<p>\n<strong><span style=\"font-size: 20px\">We strive to push the field forward using novel approaches to address environmental health concerns such as:<\/span><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-size: 18px\">Use new statistical methods to analyze the impact of chemical mixtures\u2014which reflect the reality of children\u2019s daily exposures.<\/span><\/p>\n<p><span style=\"font-size: 18px\">Connect&nbsp;cutting-edge epigenetic marks to chemical exposure to better understand how chemicals \u201cprogram\u201d health trajectories that underlie why some childhood exposures lay dormant for years and then cause disease in adulthood.<\/span><\/p>\n<p><span style=\"font-size: 18px\">Develop new exposure biomarkers to facilitate more accurate understanding of the timing, duration, and dose of toxic exposures that may have occurred years previously.<\/span><\/p>\n<p><span style=\"font-size: 18px\">Integrate animal and human study methodology to enhance our understanding of the mechanisms of toxicity.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; 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