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Qureshi s., Lee s., Ritzer L., Kim S., Steidl W., Krest G., Kasi A., Kumar V., ATF4 regulates mitochondrial dysfunction, mitophagy, and autophagy, contributing to corneal endothelial apoptosis. Scientific Reports <\/u> 2026, Jan 21; PMID: 41565836.<\/p>\n
https:\/\/https:\/\/https:\/\/pubmed.ncbi.nlm.nih.gov\/41565836\/\/\/\/<\/a><\/p>\n <\/p>\n Lee S., Kim SY., Akman HO., Qureshi S., Kasi A., Steidl W., Ritzer L., Price M., Price FW., Schon EA., Kumar V., Chronic ER Stress Disrupts Mitochondrial-Associated ER Membrane Integrity in Corneal Endothelial Cells. BioRxiv <\/u> 2026, Jan 10; PMID: 41542634.<\/p>\n https:\/\/https:\/\/https:\/\/pubmed.ncbi.nlm.nih.gov\/41542634\/\/\/<\/a><\/p>\n <\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item _builder_version=”4.27.4″ title=”2025″ title_tablet=”2025px” title_phone=”2025px” link_option_url_new_window=”off” use_background_color_gradient=”off” background_color_gradient_start=”#2b87da” background_color_gradient_end=”#29c4a9″ background_color_gradient_type=”linear” background_color_gradient_direction=”180deg” background_color_gradient_direction_tablet=”180deg” background_color_gradient_direction_phone=”180deg” background_color_gradient_direction_radial=”center” background_color_gradient_start_position=”0%” background_color_gradient_start_position_tablet=”0%” background_color_gradient_start_position_phone=”0%” background_color_gradient_end_position=”100%” background_color_gradient_end_position_tablet=”100%” background_color_gradient_end_position_phone=”100%” 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body_quote_text_shadow_blur_strength_phone=”1px” box_shadow_style=”none” box_shadow_horizontal=”box_shadow_style,%91object Object%93″ box_shadow_horizontal_tablet=”0px” box_shadow_horizontal_phone=”0px” box_shadow_vertical=”box_shadow_style,%91object Object%93″ box_shadow_vertical_tablet=”0px” box_shadow_vertical_phone=”0px” box_shadow_blur=”box_shadow_style,%91object Object%93″ box_shadow_blur_tablet=”40px” box_shadow_blur_phone=”40px” box_shadow_spread=”box_shadow_style,%91object Object%93″ box_shadow_spread_tablet=”0px” box_shadow_spread_phone=”0px” hover_transition_duration=”300ms” hover_transition_duration_tablet=”300ms” hover_transition_duration_phone=”300ms” hover_transition_delay=”0ms” hover_transition_delay_tablet=”0ms” hover_transition_delay_phone=”0ms” hover_transition_speed_curve=”ease” vertical_offset_tablet=”0″ vertical_offset_phone=”0″ horizontal_offset_tablet=”0″ horizontal_offset_phone=”0″ z_index=”1″ z_index_tablet=”1″ z_index_phone=”1″]<\/p>\n Bohm Myriam., Parekh M., Deshpande N., Cheung Q., Shatz N, Kumar V., Jurkunas U., Mitochondria-Targeted Antioxidant (MitoQ) and Nontargeted Antioxidant (Idebenone) Mitigate Mitochondrial Dysfunction in Corneal Endothelial Cells. Cornea <\/u> 2025, Jan 17; PMID: 39819808.<\/p>\n https:\/\/https:\/\/pubmed.ncbi.nlm.nih.gov\/39819808\/\/\/<\/a><\/p>\n <\/p>\n Kasi A., Steidl Will., Kumar V., Endoplasmic Reticulum-Mitochondria Crosstalk in Fuchs Endothelial Corneal Dystrophy: Current Status and Future Prospects. Int J Mol Sci <\/u> 2025, Jan 17;<\/p>\n Qureshi s., Lee s., Ritzer L., Kim S., Steidl W., Krest G., Kasi A, Kumar V., ATF4 regulates mitochondrial dysfunction, mitophagy, and autophagy, contributing to corneal endothelial apoptosis under chronic ER stress in Fuchs’ dystrophy. BioRxiv <\/u> 2024, Nov 15; PMID: 39569143.<\/p>\n https:\/\/https:\/\/pubmed.ncbi.nlm.nih.gov\/39569143\/\/<\/a><\/p>\n <\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item _builder_version=”4.27.4″ title=”2024″ title_tablet=”2024px” title_phone=”2024px” link_option_url_new_window=”off” use_background_color_gradient=”off” background_color_gradient_start=”#2b87da” background_color_gradient_end=”#29c4a9″ background_color_gradient_type=”linear” background_color_gradient_direction=”180deg” background_color_gradient_direction_tablet=”180deg” background_color_gradient_direction_phone=”180deg” background_color_gradient_direction_radial=”center” background_color_gradient_start_position=”0%” background_color_gradient_start_position_tablet=”0%” background_color_gradient_start_position_phone=”0%” background_color_gradient_end_position=”100%” background_color_gradient_end_position_tablet=”100%” background_color_gradient_end_position_phone=”100%” background_color_gradient_overlays_image=”off” 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Price M., Price F., Gonzalez F., Rogan E., Jurkunas U., Estrogen toxicity causes preferential development of Fuchs endothelial corneal dystrophy in females. Redox Biol <\/u> 2024, Feb 1; PMID: 38091879.<\/p>\n https:\/\/https:\/\/pubmed.ncbi.nlm.nih.gov\/38091879\/\/<\/a><\/p>\n <\/p>\n Qureshi s., Lee s., Ritzer L., Kim S., Steidl W., Krest G., Kasi A, Kumar V., ATF4 regulates mitochondrial dysfunction, mitophagy, and autophagy, contributing to corneal endothelial apoptosis under chronic ER stress in Fuchs’ dystrophy. BioRxiv <\/u> 2024, Nov 15; PMID: 39569143.<\/p>\n https:\/\/https:\/\/pubmed.ncbi.nlm.nih.gov\/39569143\/\/<\/a><\/p>\n <\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item _builder_version=”4.27.4″ title=”2023″ title_tablet=”2024px” title_phone=”2024px” link_option_url_new_window=”off” use_background_color_gradient=”off” background_color_gradient_start=”#2b87da” background_color_gradient_end=”#29c4a9″ background_color_gradient_type=”linear” background_color_gradient_direction=”180deg” background_color_gradient_direction_tablet=”180deg” background_color_gradient_direction_phone=”180deg” background_color_gradient_direction_radial=”center” background_color_gradient_start_position=”0%” background_color_gradient_start_position_tablet=”0%” background_color_gradient_start_position_phone=”0%” background_color_gradient_end_position=”100%” background_color_gradient_end_position_tablet=”100%” background_color_gradient_end_position_phone=”100%” background_color_gradient_overlays_image=”off” 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box_shadow_horizontal_tablet=”0px” box_shadow_horizontal_phone=”0px” box_shadow_vertical=”box_shadow_style,%91object Object%93″ box_shadow_vertical_tablet=”0px” box_shadow_vertical_phone=”0px” box_shadow_blur=”box_shadow_style,%91object Object%93″ box_shadow_blur_tablet=”40px” box_shadow_blur_phone=”40px” box_shadow_spread=”box_shadow_style,%91object Object%93″ box_shadow_spread_tablet=”0px” box_shadow_spread_phone=”0px” hover_transition_duration=”300ms” hover_transition_duration_tablet=”300ms” hover_transition_duration_phone=”300ms” hover_transition_delay=”0ms” hover_transition_delay_tablet=”0ms” hover_transition_delay_phone=”0ms” hover_transition_speed_curve=”ease” vertical_offset_tablet=”0″ vertical_offset_phone=”0″ horizontal_offset_tablet=”0″ horizontal_offset_phone=”0″ z_index=”1″ z_index_tablet=”1″ z_index_phone=”1″ icon_color=”rgba(75,140,193,0.96)”]<\/p>\n Qureshi s., Lee s., Steidl W., Ritzer L., Parise M., Chaubal A., Kumar V., Endoplasmic Reticulum Stress Disrupts Mitochondrial Bioenergetics, Dynamics and Causes Corneal Endothelial Cell Apoptosis. IOVS <\/u> 2023, Nov 1; PMID: 37962528.<\/p>\n https:\/\/https:\/\/https:\/\/pubmed.ncbi.nlm.nih.gov\/37962528\/\/\/<\/a><\/p>\n <\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2021″ open=”on” open_toggle_background_color=”#FFFFFF” closed_toggle_background_color=”#aadeef” icon_color=”#00aeef” _builder_version=”4.27.4″ _module_preset=”default” body_font=”Open Sans||||||||” body_font_size=”18px” body_line_height=”1.8em” hover_enabled=”0″ border_radii=”on|5px|5px|5px|5px” box_shadow_style=”preset3″ toggle_font=”Open Sans||||||||” closed_toggle_font=”Open Sans||||||||” sticky_enabled=”0″]<\/p>\n White TL., Deshpande., Kumar V., <\/b>Gauthier., Jurkunas UV., Cell cycle re-entry and arrest in G2\/M phase induces senescence and fibrosis in Fuchs Endothelial Corneal Dystrophy. Free Radical Biology and Medicine <\/u>2021, Jan 6; PMID: 33418109.<\/p>\n