The Krauss lab is interested in how cell-cell adhesion and signal transduction pathways interact to regulate cell fate during embryonic developmental and adult tissue regeneration. We use a wide combination of approaches to gain insight into how genes and the environment interact in causation of common birth defects, and how adult stem cells are called into action to repair injury to tissues.<\/p>\n
[\/et_pb_text][et_pb_divider color=”#00aeef” divider_position=”bottom” divider_weight=”0.5″ _builder_version=”4.16″ height=”18px” custom_margin=”3em|||” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2025\/11\/Krauss-Robert.Crop_.jpeg” title_text=”Krauss, Robert.Crop” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.27.4″ border_radii=”on|4px|4px|4px|4px” global_colors_info=”{}”][\/et_pb_image][et_pb_text admin_label=”Contact Us” _builder_version=”4.16″ background_color=”#ffffff” global_colors_info=”{}”]<\/p>\n
Robert S Krauss, PhD<\/strong><\/a> [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=”on|on|on” _builder_version=”4.16″ custom_margin=”0px|||” disabled=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n Satellite cells (SCs) are adult skeletal muscle stem cells located between the myofiber and its surrounding basal lamina, and they are the source of skeletal muscle\u2019s remarkable regenerative properties. SCs exist in a largely quiescent state in adult mice. However, upon muscle injury they are activated to proliferate and produce the myoblasts that will ultimately differentiate to form new myofibers; they also self-renew to replenish the muscle stem cell compartment. Quiescence is promoted by the SC niche, including the myofiber itself. Using a combination of conditional mouse mutants and cell biological analyses, we have shown that classical cadherins are components of the niche, required cell-autonomously by both the fiber and SC. We are continuing these studies with additional components of cadherin-based cell-cell junctions. We are also interested in the fundamental question of how the myofiber constructs and maintains a niche for SCs, as SCs are small, polarized, and mononuclear cells, whereas myofibers are large, non-polarized, and multinucleated cells. SCs and myofibers are in direct cell-cell contact (with cadherins present precisely where the two cells touch) but this junction represents a very small amount of the total myofiber cell surface. We are studying this question with a combination of in vivo and ex vivo approaches.<\/p>\n Holoprosencephaly (HPE) is a common developmental defect caused by failure to define the midline of the forebrain and\/or midface. HPE is associated with heterozygous mutations in Nodal and Hedgehog (Hh) pathway components, but clinical presentation is highly variable, and many mutation carriers are unaffected. It is therefore thought that such mutations interact with more common modifiers, genetic and\/or environmental, to produce severe patterning defects. Modifiers are difficult to identify, as their effects are context-dependent and occur within the complex genetic and environmental landscapes that characterize human populations. This has made a full understanding of HPE etiology challenging. We have developed mouse models for HPE that shed light on its complex etiology. Our studies with mouse lines carrying Hh pathway mutations on appropriate genetic backgrounds have led to identification of both genetic and environmental modifiers that synergize with the mutations to produce a spectrum of HPE phenotypes. These models favor a scenario in which multiple modifying influences\u2014both genetic and environmental, sensitizing and protective\u2014interact with bona fide HPE mutations to grade phenotypic outcomes. Despite the complex interplay of HPE risk factors, our findings have helped establish some clear concepts in HPE etiology.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_id=”projects” module_class=”projects-section” _builder_version=”4.16″ custom_margin=”-3em|||” collapsed=”off” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ custom_margin=”0px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Current Projects ” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]<\/p>\n Skeletal muscle stem cells <\/strong><\/p>\n Skeletal muscle stem cells (MuSCs) are the source of skeletal muscle\u2019s remarkable regenerative properties. MuSCs are maintained in a quiescent state during homeostasis but upon muscle injury they activate, proliferate, and differentiate to form new muscle. Mechanisms whereby quiescent stem cells sense and respond to tissue damage are, however, a persistent enigma in regenerative biology. Our recent work revealed that quiescent MuSCs have long, elaborate cellular projections that respond to injury via a Rac-to-Rho GTPase activity switch. This leads to retraction of projections and cytoskeletal remodeling, which in turn drives downstream MuSC activation events. Current studies focus on how projections sense tissue injury and how cytoskeletal regulation controls quiescence vs. activation states.<\/p>\n <\/p>\n Modeling holoprosencephaly in the mouse<\/strong><\/p>\n The causes of individual cases of most common birth defects are unknown but likely involve a combination of genetic predisposition and environmental exposures. Holoprosencephaly (HPE) is a common developmental disorder caused by failure to define the midline of the forebrain and\/or midface, and serves as a model system for this problem. HPE is associated with heterozygous mutations in Nodal, Hedgehog (HH), and other pathways, but clinical presentation is highly variable, and many mutation carriers are unaffected. It is therefore thought that such mutations interact with more common modifiers, genetic and\/or environmental, to produce severe patterning defects. We have developed mouse models for HPE that accurately reflect its complex etiology in humans. Current studies focus on molecular mechanisms whereby genetic and environmental risk factors synergize to produce adverse developmental outcomes. Such findings offer potential for preventive strategies.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_id=”publications” module_class=”publications-section” _builder_version=”4.16″ background_color=”#e8f8fc” parallax=”on” collapsed=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”publications-heading” _builder_version=”4.16″ custom_margin=”||0px|” global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_text admin_label=”publications” _builder_version=”4.27.4″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]<\/p>\n Krauss, R.S. and M. Kyba. (2025). When everything is a master regulator, nothing is. Mol Biol Cell, 36:pe3, 1-4. https:\/\/www.molbiolcell.org\/doi\/10.1091\/mbc.E24-11-0494?url_ver=Z39.882003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed<\/a><\/p>\n Hung, M., H.-F. Lo, A.G. Beckman, D. Demircioglu, G. Damle, D. Hasson, G.L. Radice, and R.S. Krauss. (2024). Cadherin-dependent adhesion is required for muscle stem cell niche anchorage and maintenance. Development<\/em>, 151<\/strong>:1-16, dev.202387. https:\/\/journals.biologists.com\/dev\/article\/151\/7\/dev202387\/346476\/Cadherin-dependent-adhesion-is-required-for-muscle?guestAccessKey=d5edfa4e-acac-4706-bd38-f64c8f9e26eb<\/a><\/p>\n Hung, M., Lo, H.-F., Jones, G.E.L., and R.S. Krauss. (2023). The muscle stem cell niche at a glance. J Cell Sci<\/em>, 136<\/strong>: jcs261200. https:\/\/journals.biologists.com\/jcs\/article\/136\/24\/jcs261200\/337756\/The-muscle-stem-cell-niche-at-a-glance?guesAccessKey=a688cfa6-000c-434c-adc4-802d89e59de2<\/a><\/p>\n Krauss, R.S. and A.P. Kann. (2023). Muscle stem cells get a new look: Dynamic cellular projections as sensors of the stem cell niche. BioEssays 45:1-9, 10.1002\/bies.202200249 https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bies.202200249<\/a><\/p>\n Lipinski, R.J. and R.S. Krauss. (2023). Gene-environment interactions in birth defect etiology: Challenges and opportunities. Curr Top Dev Biol 152:1-30. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0070215322001028?via%3Dihub<\/a><\/p>\n Krauss, R.S. (2023). Materialism meets transcendence. Searching: Our Quest for Meaning in the Age of Science. Science, 379:36. https:\/\/www.science.org\/stoken\/author-tokens\/ST-938\/full<\/a><\/p>\n Kann, A.P., Hung, M., Wang, W., Nguyen, J., Gilbert, P.M., Wu, Z., and Krauss, R.K. (2022). An injury-responsive Rac-to-Rho GTPase switch drives activation of muscle stem cells through rapid cytoskeletal remodeling.\u00a0Cell Stem Cell<\/em>, https:\/\/doi.org\/10.1016\/j.stem.2022.04.016<\/a><\/p>\n Lo, H.-F., M. Hong, and R.S. Krauss. (2021). Concepts in multifactorial etiology of developmental disorders: gene-gene and gene-environment interactions in holoprosencephaly. Front Cell Dev Biol., <\/i>10.3389\/fcell.2021.795194\u00a0\u00a0 https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2021.795194\/full<\/a><\/p>\n Lo, H-F., Hong, M., Szutorisz, H., Hurd, Y.L., and R.S. Krauss. (2021). \u03949-Tetrahydrocannabinol inhibits Hedgehog-dependent patterning during development.\u00a0Development<\/em>, 148<\/strong>(19). https:\/\/doi.org\/10.1242\/dev.199585<\/a><\/p>\n Kann, A.P., Hung, M., and R.S. Krauss. (2021). Cell-cell contact and signaling in the muscle stem cell niche.\u00a0Curr Opin Cell Biol<\/em>, 73<\/strong>:78-83. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0955067421000703<\/a><\/p>\n Hong, M., A. Christ, A. Christa, T.E. Willnow and R.S. Krauss. (2020). Cdon<\/em> mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly. eLife<\/em>, 9<\/strong>:e60351 Kann, A.P. and R.S. Krauss. (2019). Multiplexed RNAscope and immunofluorescence on whole-mount skeletal myofibers and their associated stem cells. Development<\/em>, 146<\/strong>:1-9, dev179259. https:\/\/dev.biologists.org\/content\/146\/20\/dev179259.abstract<\/a><\/p>\n Hong, M., K. Srivastava, S. Kim, B.L. Allen, D.J. Leahy, P. Hu, E. Roessler, R.S. Krauss* and M. Muenke*. (2017). BOC<\/em> is a modifier gene in holoprosencephaly. Hum Mutat<\/em>., 38<\/strong>:1464-1470. Goel, A.J., M.K. Rieder, H.H. Arnold, G.L. Radice, and R.S. Krauss. (2017). Niche cadherins control the quiescence-to-activation transition in muscle stem cells. Cell Reports<\/em>, 21<\/strong>:2236-2250. [\/et_pb_text][et_pb_button button_url=”http:\/\/www.ncbi.nlm.nih.gov\/sites\/myncbi\/1tqStacHEEGQL\/bibliograpahy\/47690495\/public\/?sort=date&direction=descending” button_text=”PubMed” _builder_version=”4.16″ custom_button=”on” button_text_size=”16″ button_bg_color=”#00aeef” button_border_width=”0″ button_border_radius=”2″ button_letter_spacing=”0.5″ button_font=”Open Sans|700|||||||” button_icon=”5||divi||400″ background_layout=”dark” global_colors_info=”{}”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_id=”team” module_class=”team-section” _builder_version=”4.16″ custom_margin=”||-3em|” collapsed=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”team-heading” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n [\/et_pb_text][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2025\/11\/IMG_1192.jpg” title_text=”Screenshot” src_last_edited=”off|desktop” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.27.4″ global_colors_info=”{}”][\/et_pb_image][et_pb_divider color=”#00aeef” divider_position=”bottom” divider_weight=”0.5″ _builder_version=”4.16″ height=”18px” custom_margin=”3em|||” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ custom_margin=”-3em|||” collapsed=”on” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Robert Krauss” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n Robert Krauss<\/strong><\/p>\n Professor<\/strong> Rob is interested in how cell adhesion and signal transduction interact to make stuff happen in developing embryos and regenerating tissues. His students and postdocs have been making him look good for a long time.<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Mingi Hong” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n Mingi Hong<\/strong><\/p>\n Research Assistant Professor<\/strong> Mingi is a Research Assistant Professor interested in gene-environment interactions during development and how they contribute to the etiology of birth defects. Living things thrive around her, including the plants in the lab and her wonderful cat.<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Vivian Lo” _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n Vivian Lo<\/strong><\/p>\n Postdoctoral Fellow<\/strong> Vivian is a postdoc interested in regulation of Shh signaling during early central nervous system development. Outside the lab, her favorite pastime is watching live sporting events in NYC, especially the US Open.<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Allison Kann” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]<\/p>\n Grace Jones<\/span><\/strong><\/p>\n PhD Student Grace is a fourth-year PhD student interested in the role of GTPases in muscle stem cell quiescence and activation. She loves trying new restaurants in New York, spending time with her cat, and finding friends who share her love for tacos and margs.<\/p>\n [\/et_pb_text][et_pb_text admin_label=”Margaret Hung” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]<\/p>\n Pranav Reddy<\/b><\/p>\n Master’s Student<\/b> Pranav is a second-year Master’s student interested in studying muscle stem cell projection dynamics during quiescence. He likes puzzles, board games, and trying to read.<\/p>\n <\/p>\n [\/et_pb_text][et_pb_text admin_label=”Margaret Hung” _builder_version=”4.16″ vertical_offset_tablet=”0″ horizontal_offset_tablet=”0″ z_index_tablet=”0″ text_text_shadow_horizontal_length_tablet=”0px” text_text_shadow_vertical_length_tablet=”0px” text_text_shadow_blur_strength_tablet=”1px” link_text_shadow_horizontal_length_tablet=”0px” link_text_shadow_vertical_length_tablet=”0px” link_text_shadow_blur_strength_tablet=”1px” ul_text_shadow_horizontal_length_tablet=”0px” ul_text_shadow_vertical_length_tablet=”0px” ul_text_shadow_blur_strength_tablet=”1px” ol_text_shadow_horizontal_length_tablet=”0px” ol_text_shadow_vertical_length_tablet=”0px” ol_text_shadow_blur_strength_tablet=”1px” quote_text_shadow_horizontal_length_tablet=”0px” quote_text_shadow_vertical_length_tablet=”0px” quote_text_shadow_blur_strength_tablet=”1px” header_text_shadow_horizontal_length_tablet=”0px” header_text_shadow_vertical_length_tablet=”0px” header_text_shadow_blur_strength_tablet=”1px” header_2_text_shadow_horizontal_length_tablet=”0px” header_2_text_shadow_vertical_length_tablet=”0px” header_2_text_shadow_blur_strength_tablet=”1px” header_3_text_shadow_horizontal_length_tablet=”0px” header_3_text_shadow_vertical_length_tablet=”0px” header_3_text_shadow_blur_strength_tablet=”1px” header_4_text_shadow_horizontal_length_tablet=”0px” header_4_text_shadow_vertical_length_tablet=”0px” header_4_text_shadow_blur_strength_tablet=”1px” header_5_text_shadow_horizontal_length_tablet=”0px” header_5_text_shadow_vertical_length_tablet=”0px” header_5_text_shadow_blur_strength_tablet=”1px” header_6_text_shadow_horizontal_length_tablet=”0px” header_6_text_shadow_vertical_length_tablet=”0px” header_6_text_shadow_blur_strength_tablet=”1px” box_shadow_horizontal_tablet=”0px” box_shadow_vertical_tablet=”0px” box_shadow_blur_tablet=”40px” box_shadow_spread_tablet=”0px” global_colors_info=”{}”]<\/p>\n Angelina Kramer<\/b><\/p>\n
Robert.Krauss@mssm.edu<\/a>
Professor, Stem Cell Biology and Regenerative Medicine<\/p>\nCurrent Projects <\/strong><\/h3>\n
The skeletal muscle stem cell niche<\/strong><\/h5>\n
<\/h5>\n
Modeling holoprosencephaly in the mouse<\/strong><\/h5>\n
Current Projects <\/strong><\/h3>\n
Featured Recent Publications<\/strong><\/h3>\n
https:\/\/elifesciences.org\/articles\/60351<\/a><\/p>\n
https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/humu.23286<\/a><\/p>\n
https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211124717315826?via%3Dihub<\/a><\/p>\nMeet the Team<\/strong><\/h3>\n
Robert.Krauss@mssm.edu<\/a><\/p>\n
Mingi.Hong@mssm.edu<\/a><\/p>\n
loh01@mssm.edu<\/a><\/p>\n
<\/strong><\/span>grace.jones@icahn.mssm.edu<\/a><\/p>\n
pranav.reddy@icahn.mssm.edu<\/a><\/p>\n
![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2025\/11\/IMG_1193-300x211.jpg\")
<\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2024\/04\/IMG_9549-e1713206150974-271x300.jpg\")
<\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2023\/04\/IMG-5589-scaled-e1684953773981-300x191.jpg\")
<\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2022\/05\/IMG_2062-2-Large-682x1024.jpeg\")
<\/p>\n![](\"https:\/\/pbs.twimg.com\/media\/Eu7IrcwWgAMah_i?format=jpg&name=small\")
![\"The](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2019\/03\/The-chck-lab-with-an-egg-1.jpg\")
![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2025\/01\/Lab-secret-santa-2024-scaled-e1736785552587-300x218.jpg\")
<\/strong><\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2024\/04\/IMG_9541-e1713206691104-271x300.jpg\")
<\/strong><\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2024\/04\/IMG_8912-scaled-e1713207429833-1024x823.jpg\")
<\/strong><\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2022\/05\/IMG_0708-Large-1-1024x768.jpeg\")
Allison wins the Terry Krulwich Doctoral Dissertation Prize!<\/strong><\/p>\n![\"The](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2019\/03\/The-secret-is-out-2.jpg\")
![\"Rob](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2019\/03\/Sundance1-1.jpg\")
![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2026\/01\/Screenshot-2026-01-28-at-4.57.09-PM-230x300.png\")
<\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2024\/04\/IMG_8856-e1713206753532-1024x525.jpg\")
<\/strong><\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2024\/04\/IMG_3362-scaled-e1713206939793.jpg\")
<\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2022\/05\/IMG_4453-Large-1024x768.jpeg\")
Allison’s defense party!<\/strong><\/p>\n![\"Krauss](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2019\/03\/Krauss-lab-at-the-March-for-science-2.jpg\")
![\"Aviva\u2019s](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2019\/03\/Avivas-defense-party-2.jpg\")
![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2019\/03\/Team-photo-2.jpg\")
![\"Krauss](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2019\/03\/Krauss-lab-at-the-2018-departmental-retreat-1.jpg\")
![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2025\/11\/IMG_1212-238x300.jpg\")
<\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2024\/04\/IMG_1790-scaled-e1713207156284-928x1024.jpg\")
<\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2024\/04\/IMG_2946-scaled-e1713207242115.jpg\")
<\/p>\n![\"\"](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2020\/12\/Convocation.Final_-300x218.jpg\")
<\/p>\n![\"RK](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2019\/03\/RK-and-ST-separated-at-birth.jpg\")
![\"Giselle\u2019s](\"https:\/\/labs.icahn.mssm.edu\/krausslab\/wp-content\/uploads\/sites\/279\/2019\/03\/Giselles-defense-party.jpg\")