{"id":5,"date":"2014-09-18T20:11:07","date_gmt":"2014-09-18T20:11:07","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/krammerlab\/?page_id=2"},"modified":"2025-12-05T17:44:51","modified_gmt":"2025-12-05T17:44:51","slug":"sample-page-2","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/krammerlab\/","title":{"rendered":"The Krammer Laboratory"},"content":{"rendered":"<h2><strong><a href=\"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2014\/09\/wf_fluvirus_all_us.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-46 alignright\" src=\"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2014\/09\/wf_fluvirus_all_us-300x300.jpg\" alt=\"wf_fluvirus_all_us\" width=\"311\" height=\"311\" srcset=\"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2014\/09\/wf_fluvirus_all_us-300x300.jpg 300w, https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2014\/09\/wf_fluvirus_all_us-150x150.jpg 150w, https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2014\/09\/wf_fluvirus_all_us-1024x1024.jpg 1024w, https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2014\/09\/wf_fluvirus_all_us.jpg 1181w\" sizes=\"auto, (max-width: 311px) 100vw, 311px\" \/><\/a><\/strong><\/h2>\n<h2><strong>Cross-reactive antibody responses towards viral surface glycoproteins: Translating basic research into novel vaccines and therapeutics<\/strong><\/h2>\n<p>The Krammer laboratory studies cross-reactive antibody responses to the surface glycoproteins of antigenically variable RNA viruses. Our main focus is on influenza viruses, but we are also interested in antibody responses to hantaviruses, filoviruses, and other emerging RNA viruses. Work done in the laboratory includes the expression and characterization of viral glycoproteins, generation of glycoprotein-directed monoclonal antibodies, and the characterization of the interaction between antibodies and surface glycoproteins; we are specifically interested in analyzing conserved epitopes and \u2013 through detailed studies \u2013 aim to elucidate the mechanisms by which these antibodies protect the host from viral infection and disease. The final goal is to translate these findings into novel vaccines and therapeutics.<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-825 aligncenter\" src=\"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2024\/09\/retreat-2024-e1727186527480.jpg\" alt=\"\" width=\"987\" height=\"488\" srcset=\"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2024\/09\/retreat-2024-e1727186527480.jpg 1586w, https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2024\/09\/retreat-2024-e1727186527480-300x148.jpg 300w, https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2024\/09\/retreat-2024-e1727186527480-1024x506.jpg 1024w, https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2024\/09\/retreat-2024-e1727186527480-768x380.jpg 768w, https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-content\/uploads\/sites\/68\/2024\/09\/retreat-2024-e1727186527480-1536x759.jpg 1536w\" sizes=\"auto, (max-width: 987px) 100vw, 987px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cross-reactive antibody responses towards viral surface glycoproteins: Translating basic research into novel vaccines and therapeutics The Krammer laboratory studies cross-reactive antibody responses to the surface glycoproteins of antigenically variable RNA viruses. Our main focus is on influenza viruses, but we are also interested in antibody responses to hantaviruses, filoviruses, and other emerging RNA viruses. Work [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-5","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-json\/wp\/v2\/pages\/5","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-json\/wp\/v2\/comments?post=5"}],"version-history":[{"count":30,"href":"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-json\/wp\/v2\/pages\/5\/revisions"}],"predecessor-version":[{"id":1080,"href":"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-json\/wp\/v2\/pages\/5\/revisions\/1080"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/krammerlab\/wp-json\/wp\/v2\/media?parent=5"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}