{"id":293,"date":"2023-09-05T21:10:53","date_gmt":"2023-09-05T21:10:53","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/kathiriyalab\/?page_id=293"},"modified":"2023-10-13T19:07:05","modified_gmt":"2023-10-13T19:07:05","slug":"publication","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/kathiriyalab\/publication\/","title":{"rendered":"Publication"},"content":{"rendered":"

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Publications<\/h1>\n

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2022<\/span><\/p>\n

<\/span><\/p>\n

Human distal airways contain a multipotent secretory cell that can regenerate alveoli.<\/a><\/span><\/h2>\n
\n

Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE. Nature. 2022 Apr;604(7904):120-126. doi: 10.1038\/s41586-022-04552-0. Epub 2022 Mar 30. PMID: 35355013; PMCID: PMC9297319.<\/span><\/span><\/span><\/p>\n<\/blockquote>\n

Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+<\/sup>\u00a0basal cell<\/a><\/span><\/h2>\n
\n

Kathiriya JJ, Wang C, Zhou M, Brumwell A, Cassandras M, Le Saux CJ, Cohen M, Alysandratos KD, Wang B, Wolters P, Matthay M, Kotton DN, Chapman HA, Peng T.<\/span>\u00a0Nat Cell Biol. 2022 Jan;24(1):10-23. doi: 10.1038\/s41556-021-00809-4. Epub 2021 Dec 30. PMID: 34969962; PMCID: PMC8761168.<\/span><\/span><\/sup><\/span><\/span><\/p>\n<\/blockquote>\n

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2021<\/span><\/h1>\n

<\/strong><\/span><\/p>\n

<\/span>An inflammatory switch for stem cell plasticity<\/strong><\/a><\/span><\/p>\n

Kathiriya JJ, Peng T. Nat Cell Biol. 2021 Sep;23(9):928-929. doi: 10.1038\/s41556-021-00752-4. PMID: 34475536; PMCID: PMC8440424.<\/span><\/span><\/sup><\/span><\/span><\/p>\n

<\/sup><\/span><\/span><\/p>\n

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2020<\/strong><\/span><\/h1>\n

<\/strong><\/span><\/p>\n

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future.<\/a><\/strong><\/span><\/h2>\n
\n

Basil MC, Katzen J, Engler AE, Guo M, Herriges MJ, Kathiriya JJ, Windmueller R, Ysasi AB, Zacharias WJ, Chapman HA, Kotton DN, Rock JR, Snoeck HW, Vunjak-Novakovic G, Whitsett JA, Morrisey EE. Cell Stem Cell. 2020 Apr 2;26(4):482-502. doi: 10.1016\/j.stem.2020.03.009. PMID: 32243808; PMCID: PMC7128675.<\/span><\/span><\/p>\n<\/blockquote>\n

<\/strong><\/span><\/h2>\n

Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis<\/a><\/strong><\/span><\/h2>\n

Strunz M, Simon LM, Ansari M, Kathiriya JJ, Angelidis I, Mayr CH, Tsidiridis G, Lange M, Mattner LF, Yee M, Ogar P, Sengupta A, Kukhtevich I, Schneider R, Zhao Z, Voss C, Stoeger T, Neumann JHL, Hilgendorff A, Behr J, O’Reilly M, Lehmann M, Burgstaller G, K\u00f6nigshoff M, Chapman HA, Theis FJ, Schiller HB. Nat Commun. 2020 Jul 16;11(1):3559. doi: 10.1038\/s41467-020-17358-3. PMID: 32678092; PMCID: PMC7366678.<\/span><\/span><\/span><\/p>\n

<\/span><\/span><\/span><\/p>\n

<\/span><\/span><\/span><\/p>\n

<\/strong><\/span><\/h2>\n

Gli1+<\/sup>\u00a0mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung<\/a><\/strong><\/span><\/h2>\n
\n

Cassandras M, Wang C, Kathiriya J, Tsukui T, Matatia P, Matthay M, Wolters P, Molofsky A, Sheppard D, Chapman H, Peng T. <\/span>\u00a0Nat Cell Biol. 2020 Nov;22(11):1295-1306. doi: 10.1038\/s41556-020-00591-9. Epub 2020 Oct 12. PMID: 33046884; PMCID: PMC7642162.<\/span><\/span><\/span><\/p>\n<\/blockquote>\n

<\/strong><\/span><\/h2>\n

Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration<\/a><\/strong><\/span><\/h2>\n
\n

Kathiriya JJ, Brumwell AN, Jackson JR, Tang X, Chapman HA.\u00a0 Cell Stem Cell. 2020 Mar 5;26(3):346-358.e4. doi: 10.1016\/j.stem.2019.12.014. Epub 2020 Jan 23. PMID: 31978363; PMCID: PMC7233183.<\/span><\/span><\/strong><\/span><\/p>\n<\/blockquote>\n

<\/strong><\/span><\/h2>\n

VEGF Drives the Car toward Better Gas Exchange<\/a><\/strong><\/span><\/h2>\n
\n

Kathiriya JJ, Chapman HA.<\/span><\/span><\/span>\u00a0Dev Cell. 2020 Mar 9;52(5):546-547. doi: 10.1016\/j.devcel.2020.02.009. PMID: 32155436; PMCID: PMC7233181.<\/span><\/span><\/span><\/p>\n<\/blockquote>\n

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2018<\/strong><\/span><\/h1>\n

<\/strong><\/span><\/p>\n

PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer<\/a><\/strong><\/span><\/h2>\n
\n

Malaney P, Palumbo E, Semidey-Hurtado J, Hardee J, Stanford K, Kathiriya JJ, Patel D, Tian Z, Allen-Gipson D, Dav\u00e9 V.\u00a0 Cell Cycle. 2018;17(8):947-962. doi: 10.1080\/15384101.2017.1388970. Epub 2018 May 31. PMID: 29108454; PMCID: PMC6103743.<\/span><\/span><\/p>\n<\/blockquote>\n

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2017<\/strong><\/span><\/h1>\n

\u00a0<\/strong><\/span><\/p>\n

Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis<\/a><\/strong><\/span><\/h2>\n
\n

Kathiriya JJ, Nakra N, Nixon J, Patel PS, Vaghasiya V, Alhassani A, Tian Z, Allen-Gipson D, Dav\u00e9 V. Cell Death Discov. 2017 Apr 10;3:17010. doi: 10.1038\/cddiscovery.2017.10. PMID: 28417017; PMCID: PMC5385413.<\/span><\/span><\/span><\/p>\n<\/blockquote>\n

<\/strong><\/span><\/h2>\n

Data on evolution of intrinsically disordered regions of the human kinome and contribution of FAK1 IDRs to cytoskeletal remodeling<\/a><\/strong><\/span><\/h2>\n
\n

Kathiriya JJ, Pathak RR, Bezginov A, Xue B, Uversky VN, Tillier ER, Dav\u00e9 V. Data Brief. 2016 Dec 8;10:315-324. doi: 10.1016\/j.dib.2016.11.099. PMID: 28004021; PMCID: PMC5157709.<\/span><\/span><\/span><\/p>\n<\/blockquote>\n

<\/strong><\/span><\/h2>\n

Structural pliability adjacent to the kinase domain highlights contribution of FAK1 IDRs to cytoskeletal remodeling<\/a><\/strong><\/span><\/h2>\n
\n

Kathiriya JJ, Pathak RR, Bezginov A, Xue B, Uversky VN, Tillier ERM, Dav\u00e9 V. Biochim Biophys Acta Proteins Proteom. 2017 Jan;1865(1):43-54. doi: 10.1016\/j.bbapap.2016.10.002. Epub 2016 Oct 5. PMID: 27718363; PMCID: PMC5127739.<\/span><\/span><\/span><\/p>\n

<\/h2>\n<\/blockquote>\n

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2014<\/strong><\/span><\/h1>\n

<\/strong><\/span><\/h1>\n

Presence and utility of intrinsically disordered regions in kinases<\/a><\/strong><\/span><\/h2>\n
\n

Kathiriya JJ, Pathak RR, Clayman E, Xue B, Uversky VN, Dav\u00e9 V. Mol Biosyst. 2014 Nov;10(11):2876-88. doi: 10.1039\/c4mb00224e. PMID: 25099472.<\/span><\/a><\/span><\/strong><\/span><\/p>\n<\/blockquote>\n

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2012<\/strong><\/span><\/h1>\n
\n

BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors<\/strong><\/span><\/a><\/h2>\n

Kathiriya JJ, Pathak RR, Clayman E, Xue B, Uversky VN, Dav\u00e9 V. Mol Biosyst. 2014 Nov;10(11):2876-88. doi: 10.1039\/c4mb00224e. PMID: 25099472.<\/span><\/p>\n<\/blockquote>\n

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