Jaymin Kathiriya, PhD

 Prinicpal Investigator

 

Jaymin is an Assistant Professor in the Departments of Medicine and Cell, Developmental, and Regenerative Biology at the Icahn School of Medicine at Mount Sinai. He is a member of the Black Family Stem Cell Institute, Institute for Airway Science, and Mount Sinai National Jewish Health Respiratory Institute. His research interests focus on understanding the signaling pathways and cellular remodeling that affect fate decisions of distal lung epithelial stem cells. He obtained his PhD at University of South Florida where he identified gene regulatory networks underpinning hypoxia signaling in profibrotic activation of lung epithelium. During his postdoctoral training under Hal Chapman at University of California, San Francisco, he discovered key stem/progenitor cell populations in mouse and human distal lung epithelium that are responsible for both normal and abnormal injury response. Of note, his work discovered previously unappreciated transdifferentiation capacity of human type 2 alveolar epithelial cells to give rise to metaplastic basal cells often observed in the lungs of patients with Idiopathic Pulmonary Fibrosis. The Kathiriya lab uses in vitro, in vivo, and in silico computational tools and techniques to study early mechanisms of stem cell activation and role of cytoskeletal remodeling in abnormal differentiation of stem cells in diseases.

 

Team

Sachin DSouza

Sachin DSouza

Associate Researcher - 1

Biological & Pharmaceutical Biotechnology, MS (St. John’s University)
Bioinformatics, M.Sc (Mangalore University)
Life Sciences, B.Sc (Mangalore University)

Tristan Tran

Tristan Tran

Associate Researcher - 1

Biology, BS (Cornell University)

Isha Sahasrabudhe

Isha Sahasrabudhe

Associate Researcher - 1

Biostatistics, MS (University of Pittsburgh School of Public Health)

Dr. Xinran Ma

Dr. Xinran Ma

Postdoctoral Fellow

Biomedical Sciences, PhD (Columbia University)
Biology, BS (Cornell University) BS (Cornell University)

Elizabeth Hospedales

Elizabeth Hospedales

Graduate Student

Biomedical Science, MS (Icahn School of Medicine at Mount Sinai)
Biomedical Science, BS (Icahn School of Medicine at Mount Sinai)

Alumni

Kelvin Zaw

Kelvin Zaw

Associate Researcher (04/01/2023 to 05/30/2024)

Biology, B.A (Hunter College)

Emily Hovan

Emily Hovan

Volunteer (11/01/2023 to 05/30/2024)

Narrative Medicine, MS (Columbia University)
Hispanic Studies, BS (Bowdoin College)