{"id":34,"date":"2026-03-30T13:15:21","date_gmt":"2026-03-30T13:15:21","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/jinlab\/?page_id=34"},"modified":"2026-03-30T17:22:05","modified_gmt":"2026-03-30T17:22:05","slug":"publications-2","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/jinlab\/home\/publications-2\/","title":{"rendered":"Publications"},"content":{"rendered":"

Jin Lab Full Publication List<\/strong><\/a><\/p>\n

Dr<\/strong>. Jin\u00a0Google Scholar Citations<\/strong><\/a><\/p>\n

2026<\/strong><\/p>\n

 <\/p>\n

Chen, H.; Dutta, R. P.; Li, Z.; Zhong, Y.; Ma, A.; Park, K. S.; Kottur, J.; Park, A.; Babault, N.; Wang, K.; Wang, D.; Xiong, Y.; Kaniskan, H. \u00dc.; Luo, M.; Parekh, S.; Jin, J.*, \u201cDiscovery of a Potent, Selective, and In Vivo Efficacious Covalent Inhibitor for Lysine Methyltransferase SETD8\u201d, Journal of Medicinal Chemistry<\/strong>, 2026, 69(4), 4255-4269.<\/p>\n

Yim, H.; Song, X.; Zhong, Y.; Hu, J.; Xiong, Y.; Jin, J.*, \u201cDiscovery of KRAS-G12D degraders via exploration of various E3 ligases\u201d, European Journal of Medicinal Chemistry<\/strong>, 2026, 307, 118635.<\/p>\n

Xia, Z.; Yang, X.; Samovich, S. N.; Tyurina, Y. Y.; Tyurin, V. A.; Kon, N.; Zhang, J.; Jiang, X.; Stockwell, B. R.; Jin, J.; Bayir, H.; Kagan, V. E.; Gu, W.*, “A GPX1\u2013OSBPL8 Axis Mediates Noncanonical In Vivo Ferroptosis and Cancer Growth Suppression”, Cell <\/strong>, 2026, Feb 19, doi: 10.1016\/j.cell.2026.01.009. PMCID: PMC12927606.<\/p>\n

Gelles, J. D.; Chen, Y.; Luna-Vargas, M. P. A.; Viacava Follis, A.; Al Noman, M. A.; Kabir, M.; Bayiokos, S. G.; Mohammed, J. N.; Sebastian, T. M.; Pham, N. D.; Shi, Y.; Jin, J.; Kriwacki, R. W.; Chipuk, J. E.*, \u201cA gated hydrophobic funnel within BAX binds bioactive lipids to potentiate pro-apoptotic function\u201d, Nature Communications <\/strong>, 2026, Feb 25, doi: 10.1038\/s41467-026-69836-9.<\/p>\n

Wang, Y.; Xiong, Y.; Liu, S.; Bao, L.; Qiu, X.; Korboukh, I.; Song, X.; Toffessi Tcheuyap, V.; Wu, S.; Chen, M.; Brugarolas, J.; Jin, J.; Wang, Y.; Luo, W.*, \u201cHIF-activated priming of TRAIL-induced cell death determines epigenetic vulnerability in kidney cancer\u201d, Cell Reports Medicine<\/strong>, 2026, Feb 18, 102630. doi: 10.1016\/j.xcrm.2026.102630.<\/p>\n

Yi, Y.; Li, Y.; Wang, R.; Yu, X.; Liu, Q.; Yum, C.; Zhang, Y.; Qiao, Y.; Szczepanski, A.; Wu, S.; Li, Q.; Fazli, L.; Shen, J.; Wang, X.; Li, X.; Mu, P.; Schaeffer, E. M.; Hundley, H. A.; Niu, H.; Chinnaiyan, A. M.; Wang, L.; Shi, J.; Jin, J.; Dong, X.; Zhao, W.; Chen, K.; Cao, Q.*, “A dual role of EZH2 in regulating A-to-I RNA editing and mRNA stability through ADAR\u201d, Nature Communications<\/strong>, 2026, find PMID.<\/p>\n

Yi, Y.; Fry, J.; Yum, C.; Wang, R.; Wu, S.; Narayan, S.; Liu, Q.; Zhang, X.; Oo, H. Z.; Xie, N.; Li, Y.; Gao, X.; Yu, X.; Hu, X.; Li, Q.; Keseroglu, K.; \u00d6zbudak, E. M.; Abdulkadir, S. A.; Chen, K.; Jin, J.; Zhao, J. C.; Dong, X.; Arango, D.; Yang, R.; Cao, Q.*, “EZH2 crosstalk with RNA methylation promotes prostate cancer progression through modulation of the m6A autoregulation pathway” Journal of Clinical Investigation<\/strong>, 2026, 136(2). doi: 10.1172\/JCI195840. PMCID: PMC12807473.<\/p>\n

 <\/p>\n

2025 (showing 16 out of 34 publications)<\/strong><\/p>\n

Hosseini, A.; Qiu, X.<\/u>; Xiong, Y.*; Chiang, K. H. N.; Catlett, J.; Kaltheuner, I.; Deng, Z.; Ghosh, S.; Shi, Y.*; Jin, J.* \u201cDiscovery of an LSD1 PROTAC Degrader\u201d, Proceedings of the National Academy Sciences of the United States of America (PNAS)<\/strong>, 2025, 122(20):e2425812122. PMCID: PMC12107161<\/a>.<\/p>\n

Qian, C.; Wang, Z.; Xiong, Y.; Zhang, D.; Zhong, Y.;<\/u>Inuzuka, H.; Qi, Y.; Xie, L.; Chen, X.; Wei, W.* ; Jin, J.* , \u201cHarnessing the Deubiquitinase\u00a0USP1\u00a0for Targeted Protein Stabilization\u201d. Journal of the American Chemical Society ,<\/strong> 2025, 147(17):14564-14573. PMCID: PMC12077936<\/a>.<\/p>\n

Zhong, Y.<\/u>; Kim, H. S.; Qian, C.; Xie, L.; Chen, X.; Xiong, Y.; Hu, J.; Chen, M.; Guccione, E.; Shen, Y.*; Jin, J.* , \u201cDiscovery of A Potent and Selective Protein Arginine Methyltransferase 5 (PRMT5) PROTAC Degrader\u201d. Journal of Medicinal Chemistry,<\/strong> 2025, 68(8): 8543\u20138563. PMCID: PMC12080994<\/a>.<\/p>\n

Deng, Z.; Catlett, J.; Lee, Y.; Wu, Q.; Xu, Z.; Xie, L.; Chen, X.; Xiong, Y.; Kaniskan, H. U.*; Jin, J.*; \u201cHarnessing the SPOP E3 Ubiquitin Ligase via Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation\u201d, Journal of Medicinal Chemistry<\/strong>, 2025, 68(8):8634-8647. PMCID: PMC12043353.<\/a><\/p>\n

Yim, H.; Sun, R.; Xu, Z.<\/u>; Kim, H. S.; Kim, M.; Cao, T.; Xie, L.; Chen, X.; Kaniskan, H. U.*; Jin, J.*; \u201cDiscovery of the First-in-class DOT1L PROTAC Degrader\u201d European Journal of Medicinal Chemistry <\/strong>, 2025, 291:117595. PMCID: PMC12045715<\/a>.<\/p>\n

Qian,C.; Lee,Y.; Han,Y.; Zhong,Y.<\/u>; Zhou,J.; Hrit, J.; Xie,L.; Chen, Q.; Kaniskan, H. U.; Chen, X.; Rothbart, S.; Cheng, X.; Xiong, Y.*; Jin, J.* , \u201cStructure-activity Relationship Studies of DNA Methyltransferase 1 (DNMT1) Monovalent Degraders\u201d. Journal of Medicinal Chemistry<\/strong>, 2025, 68(3):2903\u20132919. \u00a0PMCID: PMC11932022<\/a>.<\/p>\n

Deng, Z; Chen, L; Qian, C; Liu,J; Wu,Q; Song,X; Xiong,Y.<\/u>; Wang, Z; Hu, X; Inuzuka, H; Zhong, Y; Lin; Y; Pham, N.D.; Shi,Y; Wei ;W.*;\u00a0Jin,J.* Angewandte Chemie International Edition<\/strong>,<\/em> \u201cThe First-in-class Deubiquitinase-targeting Chimera Stabilizes and Activates cGAS.”,2025, 64(3):e202415168. PMCID: PMC11738674<\/a>.<\/a><\/span><\/p>\n

Kabir. M.; Hu, X.<\/u> Martin, T. C.; Pokushalov, D.; Kim, Y. J.; Chen, Y.; Zhong, Y.;\u00a0Wu, Q; Chipuk, J. Y.; Shi, Y; Xiong, Y.; Gu, W.; Parsons, R. E.;\u00a0and\u00a0Jin, J.* , \u201cHarnessing the TAF1 Acetyltransferase for Targeted Acetylation of the Tumor Suppressor p53\u201d, Advanced Science<\/strong>, 2025, 12(7):e2413377.<\/span>\u00a0PMCID: PMC11831463<\/a>.<\/p>\n

Xu, Z.<\/u>; Pokushalov, D.<\/u>; Kabir, M.; Lee, Y.; Chattopadhyay, M.; Jenkins, E. C.; Choo, C.; Kaniskan, H. \u00dc.; Germain, D.*; Jin, J.*<\/u>\u201cTargeting the Mitochondrial Protease ClpP for Anticancer Therapy\u201d. Journal of Medicinal Chemistry<\/strong>, 2025, 68(20):21377-21393. PMID: 41032690<\/a>.<\/p>\n

Chen, L.<\/u>; Deng, Z.<\/u>; Xiong, Y.<\/u>; Liu, J.<\/u>; Huang, D.; Wang, J.; Chen, Y.; Inuzuka, H.; Xie, L.; Chen, X.; Jin, J.*; Wei, W.* \u201cDeubiquitinase-Targeting Chimeras Mediated Stabilization of Tumor Suppressive E3 Ligase Proteins as a Strategy for Cancer Therapy\u201d. Journal of the American Chemical Society<\/strong>, 2025, 147(33):29875-29883. PMCID: PMC12395470<\/a>.<\/p>\n

Hu, X.<\/u>; Graciano, K.<\/u>; Hu, J.; Liu, C.; Zhang, J.; Xie, L.; Chen, X.; Xiong, Y.; Jin, J.*; Xu, J.* \u201cDiscovery of the first-in-class Aurora B kinase selective degrader\u201d European Journal of Medicinal Chemistry<\/strong>, 2025, 298: 118006. PMCID: PMC12379206<\/a>.<\/p>\n

Wang, Z.; Qian, C.; Xiong, Y.; Zhang, D.<\/u>; Inuzuka, H.; Zhong, Y.; Xie, L.; Chen, X.; Jin, J.*; Wei, W.*, \u201cUSP28-Based Deubiquitinase-Targeting Chimeras for Cancer Treatment”, Journal of the American Chemical Society<\/strong>,2025, 147(16):13754\u201313763. PMCID: PMC12105324<\/a>.<\/p>\n

Zhu, Z.; Chen, H.; Qiu, X.; Kaniskan, H. \u00dc.; Xie, L.; Chen, X.; Jin, J.*; Liu, P.* “(GGAA)3-based TF-PROTACs enable targeted degradation of ETV6 to inhibit Ewing sarcoma growth”, Journal of the American Chemical Society<\/strong>, 2025, 147(16):13396\u201313404. PMID: 40215343<\/a>.<\/p>\n

Teichman , E. M.; Hu , J.;<\/u> in, H.; Fisher, R. F.; Blando, A.; Hu, X.; Kaniskan , H. U; Montgomery, S. E.; Cai, M.; Parise, L.; Wang, J.; Russo, S.; Han, M.*; Jin , J.*; Morel, C.* , \u201cDesign and validation of novel brain-penetrant HCN channel inhibitors to ameliorate social stress-induced susceptible phenotype\u201d. Molecular Psychiatry, <\/strong>2025, 30(9):3937-3950.PMCID: PMC12339378<\/a>.<\/p>\n

Xie, L<\/u>; Sheehy, RN<\/u>; Muneer, A<\/u>; Xiong, Y<\/u>; Wrobel, JA; Zhang, F; Park, KS; Velez, J; Liu, J; Luo, YJ; Asrican, B; Dong, P; Li, YD; Damian, C; Quintanilla, L; Li, Y; Xu, C; Deshmukh, M; Coleman, LG Jr; Ming, GL; Song, H; Wen, Z; Jin, J*; Song, J*; Chen, X*. \u201cDevelopment of a brain-penetrant G9a methylase inhibitor to target Alzheimer’s disease-associated proteopathology\u201d. Nature Communication<\/strong>, \u00a02025. 16(1):4222. PMCID: PMC12056044<\/a>.<\/p>\n

Martinez, Criseyda; Xiong, Yan;<\/u> Bartkowski, Alison; Harada, Ibuki; Ren, Xiaoxiao; Byerly, Jessica; Port, Elisa; Jian\u00a0Jin*; Irie, Hanna*. \u201cA PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells\u201d, Cell Chemical Biology<\/strong>, 2025, 32(2):255-266.E8. PMCID: PMC11845306.<\/a><\/span><\/p>\n

2024 (showing 10 out of 15 publications) <\/strong><\/p>\n

Inuzuka, H; Qian, Chao; Qi,Y; <\/u> Xiong, Y; Wang, C;Wang,Z; Zhang, D;Zhang, C; Jin, J*; Wei, W*; ACS Pharmacology & Translational Science <\/strong>, \u201cTargeted Degradation of Receptor-Interacting Protein Kinase 1 to Modulate the Necroptosis Pathway\u201d, \u00a02024, 7, 3518-3526. PMCID: PMC11555510.<\/a><\/span><\/p>\n

Xue Z; Qin L; Xuan H.; Luo K.<\/u>; Huang M; Xie, L; Su, Y.; Xu L; Harsh, J.; Dale, B.; Shi, X.; Chen, X.; Kaniskan, H\u00dc.; Jin, J*., Wen, H.*, Science Advances,<\/strong> \u201cA potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression\u201d.\u00a02024 Aug 30;10(35).eado1432. PMID:39196923<\/a>.<\/span>\u00a0PMCID:\u00a0PMC11352836<\/p>\n

Hu,X; Kabir, M;<\/u><\/span> Lin, Y; Xiong Y; Parsons, R;\u00a0 <\/span>Gu, W; Jin, J*.\u00a0Journal of Medicinal Chemistry<\/strong> <\/b>\u201cDesign, Synthesis, and Evaluation of p53Y220C Acetylation Targeting Chimeras (AceTACs)\u201d, , August, <\/i> 2024, 67, 14633\u221214648 PMID:39169826<\/a>.<\/p>\n

Wang, S, E.; Xiong, Y.<\/u>;Jang, M, A,; Park, K, S.; Donahue, M.; Velez J.; Jin J.*; Jiang, Y, H.*, Molecular Therapy<\/strong><\/em>, \u201cNewly developed oral bioavailable EHMT2 inhibitor as a potential epigenetic therapy for Prader-Willi syndrome\u201d, 2024 Aug 7;32(8):2662-2675. PMID: 38796700<\/a>;.doi: https:\/\/doi.org\/doi:10.1016\/j.ymthe.2024.05.034<\/a><\/p>\n

Kabir<\/span>, M.<\/u>;\u00a0 Qin, L.<\/u>;\u00a0 Luo, K.;\u00a0 Xiong, Y.;\u00a0 Sidi, R. A.;\u00a0 Park, K.-S.*; Jin, J.*, “Discovery and characterization of a novel Cereblon-recruiting PRC1 bridged PROTAC degrader.” Journal of Medicinal Chemistry<\/strong>. <\/em>2024,\u00a067<\/span>:6880-6892. <\/span>PMID: 38607318<\/a>.<\/span><\/span><\/p>\n

Velez, J.<\/u>;\u00a0 Han, Y.<\/u>;\u00a0 Yim, H.;\u00a0 Yang, P.;\u00a0 Deng, Z.;\u00a0 Park, K.-s.;\u00a0 Kabir, M.;\u00a0 Kaniskan, H. \u00dc.;\u00a0 Xiong, Y.*; Jin, J.<\/strong>*, Discovery of the first-in-class G9a\/GLP PROTAC degrader. \u00a0Journal of Medicinal Chemistry.\u00a0<\/strong> 2024, <\/span>67<\/span>(8)<\/span>:6397-6409.\u00a0PMID: 28602846.<\/a><\/span><\/span><\/span><\/p>\n

Liu, J; Hu, X.; Luo, K; Xiong, Y; Chen, L.<\/u>;\u00a0 Wang, Z.;\u00a0Inuzuka, H.;\u00a0 Qian, C.;\u00a0 Yu, X.;\u00a0 Xie, L.;\u00a0 Muneer, A.;\u00a0 Zhang, D.;\u00a0 Paulo, J. A.;\u00a0 Chen, X.;\u00a0 Jin, J.*; Wei, W.*, Journal of the American Chemical Society<\/strong><\/em>“, USP7-based deubiquitinase-targeting chimeras stabilize AMPK.”\u00a0 2024,\u00a0146, 16, 11507\u201311514;<\/span> PMID: 38597345.<\/a><\/span><\/p>\n

Xiong, Y.<\/u>;\u00a0 Greschik, H.<\/u>;\u00a0 Johansson, C.;\u00a0 Seifert, L.;\u00a0 Gamble, V.;\u00a0 Park, K.-s.;\u00a0 Fagan, V.;\u00a0 Li, F.;\u00a0 Chau, I.;\u00a0 Vedadi, M.;\u00a0 Arrowsmith, C. H.;\u00a0 Brennan, P.;\u00a0 Fedorov, O.;\u00a0 Jung, M.;\u00a0 Farnie, G.;\u00a0 Liu, J.;\u00a0 Oppermann, U. *;\u00a0 Sch\u00fcle, R. *; Jin, J.<\/strong> *, Discovery of a potent, selective, and cell-active SPIN1 inhibitor.\u00a0 Journal of Medicinal Chemistry<\/strong>.<\/em> 2024, 67(7):5837-5853. PMID:\u00a0<\/strong><\/span>38533580.<\/a><\/span><\/span><\/p>\n

Wang, Z.<\/u>;\u00a0 Zhang, D.;\u00a0 Qiu, X.;\u00a0 Inuzuka, H.;\u00a0 Xiong, Y.;\u00a0 Liu, J.;\u00a0 Chen, L.;\u00a0 Chen, H.;\u00a0 Xie, L.;\u00a0 Kaniskan, H. \u00dc.;\u00a0 Chen, X.;\u00a0 Jin, J. *; Wei, W. *, Journal of the American Chemical Society <\/strong>. “Structurally specific Z-DNA proteolysis targeting chimera enables targeted degradation of adenosine deaminase acting on RNA”, 2024,\u00a0 146<\/em> (11): 7584-7593. PMID:\u00a0<\/span>38469801.<\/a><\/span><\/span><\/p>\n

Velez, J.<\/u>;\u00a0 Dale, B.;\u00a0 Park, K.-S.;\u00a0 Kaniskan, H. \u00dc.;\u00a0 Yu, X. *; Jin, J. *, “Discovery of a novel, highly potent EZH2 PROTAC degrader for targeting non-canonical oncogenic functions of EZH2”. \u00a0European Journal of Medicinal Chemistry, <\/strong>2024,<\/strong> 267<\/em>, 116154. PMID: 38602846.<\/a>,<\/span><\/p>\n

2023 (showing 12 out of 24 publications) <\/strong><\/p>\n

Dang, F.;<\/u> Bai, L.;<\/u> Dong, J.;<\/u> Hu, X.;<\/u> Wang, J.; Paulo, J. A.; Xiong, Y.; Liang, X.; Sun, Y.; Chen, Y.; Guo, M.; Wang, X.; Huang, Z.; Inuzuka, H.; Chen, L.; Chu, C.; Liu, J.; Zhang, T.; Rezaeian, A.-H.; Liu, J.; Kaniskan, H. \u00dc.; Zhong, B.; Zhang, J.; Letko, M.; Jin, J. *; Lan, K. *; Wei, W. *, USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice.\u00a0 Science Translational Medicine<\/strong>. 2023,<\/strong> 15<\/em> (725): eadh7668. PMID: 38055802<\/a>.<\/p>\n

Yu, X.; Li, D.; Kottur, J.<\/u>; Kim, H. S.; Herring, L. E.; Yu, Y.; Xie, L.; Hu, X.; Chen, X.; Cai, L.; Liu, J.; Aggarwal, A. K.; Wang, G. G. *; Jin, J.*, Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer. Journal of Medicinal Chemistry<\/strong>. <\/em><\/strong>2023, <\/strong><\/em>66(23): 16168\u201316186. PMID: 38019706.<\/a><\/span><\/p>\n

Kabir, M.; Sun, N.; Hu, X.;<\/span> Martin, T. C.; Yi, J.; Zhong, Y.; Xiong, Y.; Kaniskan, H. \u00dc.; Gu, W.; Parsons, R.; Jin, J.*; Acetylation Targeting Chimera Enables Acetylation of the Tumor Suppressor p53. Journal of the American Chemical Society<\/em><\/strong>\u00a02023,\u00a0145(27):14932-14944. PMID: 37365684.<\/span><\/a><\/p>\n

Wang Z.; Liu J.; Qiu X.; Zhang D.; Inuzuka H.; Chen L.; Chen H.; Xie L.; Kaniskan H\u00dc.; Chen X.; Jin J.* ; Wei W.* , Methylated Nucleotide-Based Proteolysis-Targeting Chimera Enables Targeted Degradation of Methyl-CpG-Binding Protein 2. Journal of the American Chemical Society <\/strong><\/em>. 2023, 145(40): 21871\u201321878. PMID: 37774414<\/a>.<\/span><\/p>\n

Velez, J.; Kaniskan, H. \u00dc.*; Jin, J.*; Recent advances in developing degraders & inhibitors of lysine methyltransferases. Current Opinion in Chemical Biology,<\/strong>\u00a02023, 76:102356. PMID: 37379717.<\/span><\/a><\/p>\n

Kabir, M.; Yu, X.; Kaniskan, H. \u00dc.*; Jin, J.*; Chemically induced degradation of epigenetic targets. Chemical Society Reviews,<\/em><\/strong>\u00a0<\/strong><\/em>2023, 52(13):4313-4342. PMID:\u00a0<\/span>37314393.<\/span><\/a><\/span><\/span><\/p>\n

Zhao, N.; Ho, J. S. Y.; Meng, F.;<\/span> Zheng, S.; Kurland, A. P.; Tian, L.; Rea-Moreno, M.; Song, X.; Seo, J. S.; Kaniskan, H. \u00dc.; Te Velthuis, A. J. W.; Tortorella, D.; Chen, Y. W.; Johnson, J. R.; Jin, J.*; Marazzi, I.*; Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics. Cell Host Microbe,<\/strong><\/em>\u00a02023, 31(7):1154-1169.e10. PMID: 37339625.<\/span><\/a><\/p>\n

Wang, Z.; Liu, J.<\/span>; Chen, H.; Qiu, X.; Xie, L.; Kaniskan, H. \u00dc.; Chen, X.; Jin, J.*; Wei, W.*; Telomere Targeting Chimera Enables Targeted Destruction of Telomeric Repeat-Binding Factor Proteins. Journal of the American Chemical Society<\/strong>.<\/strong><\/em> 2023, 145(19):10872-10879. PMID: 37141574.<\/span><\/a><\/p>\n

Yu, X.; Wang, J.;<\/span> Gong, W.; Ma, A.; Shen, Y.; Zhang, C.; Liu, X.; Cai, L.; Liu, J.; Wang, G. G.*; Jin, J.*; Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader. Oncogene<\/i><\/strong>, 2023, 42(13):994-1009. PMID:\u00a0<\/span>36747009.<\/span><\/span><\/a><\/span><\/p>\n

Park, K. S.; Qin, L.; Kabir, M.; Luo, K.; Dale, B.; Zhong, Y.; Kim, A.; Wang, G. G.; Kaniskan, H. \u00dc.; Jin, J*; Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy. Advanced science (Weinheim, Baden-W\u00fcrttemberg, Germany)<\/strong>.<\/strong><\/i>\u00a02023, 10(10):e2205573. PMID:\u00a0<\/a><\/span><\/span>36737841.<\/span><\/a><\/span><\/span><\/p>\n

Sun, N.; Kabir, M.;<\/span> Lee, Y.; Xie, L.; Hu, X.; Velez, J.; Chen, X.; Kaniskan, H. \u00dc.*; & Jin, J*; Discovery of the First Lactate Dehydrogenase Proteolysis Targeting Chimera Degrader for the Treatment of Pancreatic Cancer. Journal of Medicinal Chemistry. <\/i><\/strong>2023, 66(1):596-610. PMID:\u00a0<\/span>36538511.<\/span><\/a><\/span><\/p>\n

Marcellino, B. K.; Yang, X.; \u00dcmit Kaniskan, H.;<\/span> Brady, C.; Chen, H.; Chen, K.; Qiu, X.; Clementelli, C.; Herschbein, L.; Li, Z.; Elghaity-Beckley, S.; Arandela, J.; Kelly, B.; Hoffman, R.; Liu, J.; Xiong, Y.; Jin, J.*; Shih, A. H.*; An MDM2 degrader for treatment of acute leukemias. Leukemia<\/i><\/strong>, 2023, 37(2):370-378. PMID:\u00a0<\/span>36309559<\/a><\/span><\/span><\/p>\n

For papers published before 2023, please see Dr. Jin’s full publication list <\/strong><\/p>\n

Jin Lab by year Tabs <\/a>
\nJin Lab Full Publication List <\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Jin Lab Full Publication List Dr. Jin\u00a0Google Scholar Citations 2026   Chen, H.; Dutta, R. P.; Li, Z.; Zhong, Y.; Ma, A.; Park, K. S.; Kottur, J.; Park, A.; Babault, N.; Wang, K.; Wang, D.; Xiong, Y.; Kaniskan, H. \u00dc.; Luo, M.; Parekh, S.; Jin, J.*, \u201cDiscovery of a Potent, Selective, and In Vivo Efficacious […]<\/p>\n","protected":false},"author":43,"featured_media":0,"parent":193,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-34","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/34","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/users\/43"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/comments?post=34"}],"version-history":[{"count":895,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/34\/revisions"}],"predecessor-version":[{"id":2414,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/34\/revisions\/2414"}],"up":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/193"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/media?parent=34"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}