{"id":2133,"date":"2025-05-05T19:54:12","date_gmt":"2025-05-05T19:54:12","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/jinlab\/?page_id=2133"},"modified":"2025-05-16T14:38:59","modified_gmt":"2025-05-16T14:38:59","slug":"2024-publications","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/jinlab\/2024-publications\/","title":{"rendered":"2024 publications"},"content":{"rendered":"

Jin Lab Full Publication List<\/strong><\/a><\/p>\n

2024<\/strong><\/p>\n

Selective 12 of total 16 of 2024 Publications<\/strong><\/p>\n

Inuzuka, H; Qian, Chao; Qi,Y; <\/u> Xiong, Y; Wang, C;Wang,Z; Zhang, D;Zhang, C; Jin, J*; Wei, W*; ACS Pharmacology & Translational Science <\/strong>, \u201cTargeted Degradation of Receptor-Interacting Protein Kinase 1 to Modulate the Necroptosis Pathway\u201d, https:\/\/doi.org\/10.1021\/acsptsci.4c00421<\/a> 2024, 7, 3518-3526.<\/span><\/p>\n

Corbin, J.; Yu, X.; Cai, L.; Jin, J.; Wang, G. G.* Oncogene <\/strong>, \u201cEZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth\u201d, 2024, 43, 2722-2736. PMID:39112519<\/a> <\/span><\/p>\n

Nigam, A. K.; Hurley, M. F. D.; Lid, F.; Konko\u013eov\u00e1e, E.; Kl\u00edmae, M.; Tryl\u010dov\u00e1e, J.; Pollice, R.; \u00c7inaro\u01e7luh, S. S.; Levin-Konigsbergb, R.; Handjayafg, J.; Schapiradi, M.; Chaud, R.; Perveen, S.; Ho-Leung Ng, H.; Kaniskan, \u00dc.; Hank, Y.; Singhl, S.; Gorgullamno, C.; Kundajeab, A.; Jin, J.; Voelz, V. A.; Webere, J.; Nenckae, R.; Bourae, E.; Vedadi, M.*; Aspuru-Guzik, A.* Digital Discovery <\/strong>, \u201cApplication of established computational techniques to identify potential SARS-CoV-2 Nsp14-MTase inhibitors in low data regimes\u201d. 2024, 3, 1327-1341. doi: https:\/\/doi.org\/10.1016\/j.chembiol.2024.10.008<\/a> <\/span><\/p>\n

Xue Z; Qin L; Xuan H.; Luo K.<\/u>; Huang M; Xie, L; Su, Y.; Xu L; Harsh, J.; Dale, B.; Shi, X.; Chen, X.; Kaniskan, H\u00dc.; Jin, J*., Wen, H.*, Science Advances,<\/strong> \u201cA potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression\u201d.\u00a02024 Aug 30;10(35).eado1432. PMID:39196923<\/a>.<\/span>\u00a0PMCID:\u00a0PMC11352836<\/p>\n

Graboski, A.L.<\/u>;<\/span>Simpson,J.B.; Pellock;S.J.; Mehta, N.; Creekmore, B.C.; Ariyarathna; Y.; Bhatt, A.P.; Jariwala,P.B.; Sekela, J.J.; Kowalewski, M.E.; Barker, N.K.; Mordant, A.L.; Borlandelli, V.B.; Overkleeft, H.; Herring, L.E.; Jin, J.<\/b>; I James L, Redinbo,M.R.\u00a0RSC Chemical Biology Journal<\/strong> \u201cAdvanced piperazine-containing inhibitors target microbial \u03b2-glucuronidases linked to gut toxicity.\u201d PMID: 39211470<\/a>; PubMed Central PMCID: PMC11353122. RSC Chem Biol. 2024 Jul 16;5(9):853-865<\/p>\n

Hu,X; Kabir, M;<\/u><\/span> Lin, Y; Xiong Y; Parsons, R;\u00a0 <\/span>Gu, W; Jin, J*.\u00a0Journal of Medicinal Chemistry<\/strong> <\/b>\u201cDesign, Synthesis, and Evaluation of p53Y220C Acetylation Targeting Chimeras (AceTACs)\u201d, , August, <\/i> 2024, 67, 14633\u221214648 PMID:39169826 <\/a><\/p>\n

Wang, S, E.; Xiong, Y.<\/u>;Jang, M, A,; Park, K, S.; Donahue, M.; Velez J.; Jin J.*; Jiang, Y, H.*, Molecular Therapy<\/strong><\/em>, \u201cNewly developed oral bioavailable EHMT2 inhibitor as a potential epigenetic therapy for Prader-Willi syndrome\u201d, 2024 Aug 7;32(8):2662-2675. PMID: 38796700<\/a>;.doi: https:\/\/doi.org\/doi: 10.1016\/j.ymthe.2024.05.034<\/a><\/p>\n

Kabir<\/span>, M.<\/u>;\u00a0 Qin, L.<\/u>;\u00a0 Luo, K.;\u00a0 Xiong, Y.;\u00a0 Sidi, R. A.;\u00a0 Park, K.-S.*; Jin, J.*, “Discovery and characterization of a novel Cereblon-recruiting PRC1 bridged PROTAC degrader.” Journal of Medicinal Chemistry<\/strong>. <\/em>2024,\u00a067<\/span>:6880-6892. <\/span>PMID: 38607318<\/a>.<\/span><\/span><\/p>\n

Velez, J.<\/u>;\u00a0 Han, Y.<\/u>;\u00a0 Yim, H.;\u00a0 Yang, P.;\u00a0 Deng, Z.;\u00a0 Park, K.-s.;\u00a0 Kabir, M.;\u00a0 Kaniskan, H. \u00dc.;\u00a0 Xiong, Y.*; Jin, J.*, Discovery of the first-in-class G9a\/GLP PROTAC degrader. \u00a0Journal of Medicinal Chemistry.\u00a0<\/strong> 2024, <\/span>67<\/span>(8)<\/span>:6397-6409.\u00a0PMID: 28602846.<\/a><\/span><\/span><\/span><\/p>\n

Velez, J.<\/u>;\u00a0 Dale, B.;\u00a0 Park, K.-S.;\u00a0 Kaniskan, H. \u00dc.;\u00a0 Yu, X. *; Jin, J. *, “Discovery of a novel, highly potent EZH2 PROTAC degrader for targeting non-canonical oncogenic functions of EZH2”. \u00a0European Journal of Medicinal Chemistry,<\/strong>.<\/em><\/strong> 2024,<\/strong> 267<\/em>, 116154. PMID: 38602846.<\/a>,<\/span><\/p>\n

Kim, Y.;\u00a0 Gumpper, R. H.;\u00a0Liu, Y;\u00a0 Kocak, D. D.;\u00a0 Xiong, Y.;\u00a0 Cao, C.;\u00a0 Deng, Z.;\u00a0 Krumm, B. E.;\u00a0 Jain, M. K.;\u00a0 Zhang, S.;\u00a0 Jin, J.*; Roth, B. L.*, Nature <\/strong><\/em> “Bitter taste receptor activation by cholesterol and an intracellular tastant.” 2024,<\/strong>\u00a0628<\/span>(8008)<\/span>:664-671<\/span>. PMID: 38600377.<\/a><\/span><\/p>\n

Liu, J; Hu, X.; Luo, K; Xiong, Y; Chen, L.<\/u>;\u00a0 Wang, Z.;\u00a0Inuzuka, H.;\u00a0 Qian, C.;\u00a0 Yu, X.;\u00a0 Xie, L.;\u00a0 Muneer, A.;\u00a0 Zhang, D.;\u00a0 Paulo, J. A.;\u00a0 Chen, X.;\u00a0 Jin, J.*; Wei, W.*, Journal of the American Chemical Society<\/strong><\/em>“, USP7-based deubiquitinase-targeting chimeras stabilize AMPK.”\u00a0 2024,\u00a0Apr 10;<\/span> PMID: 38597345.<\/a><\/span><\/p>\n

Xiong, Y.<\/u>;\u00a0 Greschik, H.<\/u>;\u00a0 Johansson, C.;\u00a0 Seifert, L.;\u00a0 Gamble, V.;\u00a0 Park, K.-s.;\u00a0 Fagan, V.;\u00a0 Li, F.;\u00a0 Chau, I.;\u00a0 Vedadi, M.;\u00a0 Arrowsmith, C. H.;\u00a0 Brennan, P.;\u00a0 Fedorov, O.;\u00a0 Jung, M.;\u00a0 Farnie, G.;\u00a0 Liu, J.;\u00a0 Oppermann, U. *;\u00a0 Sch\u00fcle, R. *; Jin, J. *, Discovery of a potent, selective, and cell-active SPIN1 inhibitor.\u00a0 Journal of Medicinal Chemistry<\/strong>.<\/em> 2024, 67(7):5837-5853. PMID:\u00a0<\/strong><\/span>38533580.<\/a><\/span><\/span><\/p>\n

Wang, Z.<\/u>;\u00a0 Zhang, D.;\u00a0 Qiu, X.;\u00a0 Inuzuka, H.;\u00a0 Xiong, Y.;\u00a0 Liu, J.;\u00a0 Chen, L.;\u00a0 Chen, H.;\u00a0 Xie, L.;\u00a0 Kaniskan, H. \u00dc.;\u00a0 Chen, X.;\u00a0 Jin, J. *; Wei, W. *, Journal of the American Chemical Society <\/strong>. “Structurally specific Z-DNA proteolysis targeting chimera enables targeted degradation of adenosine deaminase acting on RNA”, 2024,\u00a0 146<\/em> (11): 7584-7593. PMID:\u00a0<\/span>38469801.<\/a><\/span><\/span><\/p>\n

Nylund, P.<\/u>;\u00a0 Garrido-Zabala, B.;\u00a0 P\u00e1rraga, A. A.;\u00a0 Vasquez, L.;\u00a0 Pyl, P. T.;\u00a0 Harinck, G. M.;\u00a0 Ma, A.; \u00a0Jin, J.;\u00a0 \u00d6berg, F.;\u00a0 Kalushkova, A.; Wiklund, H. J.*, PVT1 interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma. Haematologica<\/em><\/strong>, 2024, 109<\/em> (2): 567-577. PMID: 37496441.<\/a><\/p>\n

For papers published before 2021, please see Dr. Jin’s full publication list <\/strong><\/p>\n

Jin Lab Full Publication List<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Jin Lab Full Publication List 2024 Selective 12 of total 16 of 2024 Publications Inuzuka, H; Qian, Chao; Qi,Y; Xiong, Y; Wang, C;Wang,Z; Zhang, D;Zhang, C; Jin, J*; Wei, W*; ACS Pharmacology & Translational Science , \u201cTargeted Degradation of Receptor-Interacting Protein Kinase 1 to Modulate the Necroptosis Pathway\u201d, https:\/\/doi.org\/10.1021\/acsptsci.4c00421 2024, 7, 3518-3526. Corbin, J.; Yu, […]<\/p>\n","protected":false},"author":43,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2133","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/2133","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/users\/43"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/comments?post=2133"}],"version-history":[{"count":8,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/2133\/revisions"}],"predecessor-version":[{"id":2274,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/2133\/revisions\/2274"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/media?parent=2133"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}