{"id":193,"date":"2026-03-30T13:40:19","date_gmt":"2026-03-30T13:40:19","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/jinlab\/?page_id=193"},"modified":"2026-03-30T17:35:11","modified_gmt":"2026-03-30T17:35:11","slug":"home","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/jinlab\/","title":{"rendered":"Home"},"content":{"rendered":"

Welcome to the Jin Lab! The Laboratory for Medicinal Chemistry, Chemical Biology & Drug Discovery<\/span><\/h1>\n

Jian Jin laboratory has three main research topics: (1) discover selective inhibitors of histone methyltransferases (HMTs), (2) discover biased ligands of G protein-coupled receptors (GPCRs), and (3) discover novel degraders targeting oncogenic proteins.<\/strong><\/p>\n

Selective, Small-Molecule Inhibitors of Protein Methyltransferases Developed by Jin Lab (click to enlarge)
\n<\/strong><\/p>\n

\"\"<\/a><\/p>\n

(Science Translational Medicine<\/em>, 2021<\/strong>)<\/p>\n

\"\"<\/a><\/span><\/h1>\n

(Ref:\u00a0Nature Chemical Biology<\/em> 2020<\/strong> volume 16, pages 214\u2013222)<\/p>\n

\"\"<\/p>\n

\"\"<\/a>\"\"<\/a><\/p>\n

September, 2024<\/strong><\/p>\n

\"grpPhoto\"<\/a><\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Welcome to the Jin Lab! The Laboratory for Medicinal Chemistry, Chemical Biology & Drug Discovery Jian Jin laboratory has three main research topics: (1) discover selective inhibitors of histone methyltransferases (HMTs), (2) discover biased ligands of G protein-coupled receptors (GPCRs), and (3) discover novel degraders targeting oncogenic proteins. Selective, Small-Molecule Inhibitors of Protein Methyltransferases Developed […]<\/p>\n","protected":false},"author":43,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"open","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-193","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/193","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/users\/43"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/comments?post=193"}],"version-history":[{"count":28,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/193\/revisions"}],"predecessor-version":[{"id":2252,"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/pages\/193\/revisions\/2252"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/jinlab\/wp-json\/wp\/v2\/media?parent=193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}