- \n
- Craniosynostosis<\/span><\/li>\n
- Cleft lip and palate\u00a0<\/span><\/li>\n
- Mandibular dysgenesis\u00a0<\/span><\/li>\n
- Limb dysplasias<\/span><\/li>\n
- Neural tube defects<\/span><\/li>\n
- Crouzon syndrome\u00a0<\/span><\/li>\n
- Apert syndrome<\/span><\/li>\n
- Treacher Collins syndrome\u00a0<\/span><\/li>\n
- Goldenhar syndrome\u00a0<\/span><\/li>\n
- Moebius syndrome\u00a0<\/span><\/li>\n
- Pierre-Robin complex<\/span><\/li>\n
- Roberts syndrome<\/span><\/li>\n
- Bear-Stevenson syndrome<\/span><\/li>\n
- Oculodentodigital dysplasia\u00a0<\/span><\/li>\n
- & other phenotypes related to craniofacial and limb disorders!\u00a0<\/span><\/li>\n<\/ul>\n
To dissect these phenotypes we apply a combination of genetic, genomic, cellular and molecular biology approaches, genetic engineering, next generation sequencing, bioinformatics, systems biology, and clinical tools.\u00a0<\/span><\/p>\n
We are also involved in GWASs being conducted on non-syndromic congenital anomalies for isolated craniosynostosis and cleft lip with or without cleft palate.\u00a0<\/span><\/p>\n
Our projects have a direct clinical impact<\/strong> for patients with malformation disorders and for the support and management they may require.<\/span><\/p>\n
<\/p>\n
![\"\"](\"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-content\/uploads\/sites\/181\/2021\/04\/Combined-Figure-2-Figure-5_v2.jpg\")
<\/a><\/h1>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Our Research<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"
Our research centers on elucidating the pathogenesis of pediatric human malformation disorders and genetic birth defects, including:\u00a0<\/span><\/p>
- Craniosynostosis<\/span><\/li>
- Cleft lip and palate\u00a0<\/span><\/li>
- Mandibular dysgenesis\u00a0<\/span><\/li>
- Limb dysplasias<\/span><\/li>
- Neural tube defects<\/span><\/li>
- Crouzon syndrome\u00a0<\/span><\/li>
- Apert syndrome<\/span><\/li>
- Treacher Collins syndrome\u00a0<\/span><\/li>
- Goldenhar syndrome\u00a0<\/span><\/li>
- Moebius syndrome\u00a0<\/span><\/li>
- Pierre-Robin complex<\/span><\/li>
- Roberts syndrome<\/span><\/li>
- Bear-Stevenson syndrome<\/span><\/li>
- Oculodentodigital dysplasia\u00a0<\/span><\/li>
- & other phenotypes related to craniofacial and limb disorders!\u00a0<\/span><\/li><\/ul>
To dissect these phenotypes we apply a combination of genetic, genomic, cellular and molecular biology approaches, genetic engineering, next generation sequencing, bioinformatics, systems biology, and clinical tools.\u00a0<\/span><\/p>
We are also involved in GWASs being conducted on non-syndromic congenital anomalies for isolated craniosynostosis and cleft lip with or without cleft palate.\u00a0<\/span><\/p>
Our projects have a direct clinical impact for patients with malformation disorders and for the support and management they may require.<\/span><\/p>
\u00a0<\/p>
<\/a><\/h1>","_et_gb_content_width":"","footnotes":""},"class_list":["post-3","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/pages\/3","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/comments?post=3"}],"version-history":[{"count":22,"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/pages\/3\/revisions"}],"predecessor-version":[{"id":563,"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/pages\/3\/revisions\/563"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/media?parent=3"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}} - Cleft lip and palate\u00a0<\/span><\/li>
- Cleft lip and palate\u00a0<\/span><\/li>\n