{"id":15,"date":"2016-06-20T15:00:57","date_gmt":"2016-06-20T15:00:57","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/jabslab\/?page_id=15"},"modified":"2023-02-09T20:03:15","modified_gmt":"2023-02-09T20:03:15","slug":"home","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/jabslab\/","title":{"rendered":"Ethylin Wang Jabs Laboratory"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_fullwidth_header _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-content\/uploads\/sites\/181\/2016\/06\/Website.jpg&#8221;]<\/p>\n<h1>WELCOME TO THE JABS LAB<\/h1>\n<p>[\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;10px||10px||false|false&#8221;][et_pb_row column_structure=&#8221;3_4,1_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;10px||10px||false|false&#8221;][et_pb_column type=&#8221;3_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text admin_label=&#8221;Text&#8221; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;]<\/p>\n<p><span style=\"font-weight: 400\">The Jabs lab studies <strong>human malformation disorders<\/strong> and <strong>birth defects<\/strong> applying genetic and genomic tools. We profile clinical samples, animal models, and cellular systems using a combination of next generation sequencing technologies and wet lab experimentation. Our goal is to <strong>elucidate the pathogenesis<\/strong> of these disorders to identify genes, mechanisms, and pathways that can be applied to preventative medicine (genetic testing and counseling) and therapeutic development (drug development and gene therapies).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">We aim to enhance our understanding of<strong> embryonic and neonatal development<\/strong> by:\u00a0<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Identifying genes underlying genetic syndromes and birth defects.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Elucidating the biological landscape of birth defects.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Uncovering mechanisms and pathways that can be used to develop new therapies and drugs.\u00a0<\/span><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400\">Our <strong>interests<\/strong> lie in:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Neonatal and pediatric development\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Multi-scale omics of birth defects\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Genetic epidemiology of human malformation disorders\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Next generation sequencing\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Drug development &amp; repurposing\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Gene therapies<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Psychosocial impact of living with human malformation disorders<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Over the past 30 years, Dr. Jabs and her team have identified more than 20 genes that cause birth defects, and contributed research to 50 other disorders.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">We are actively recruiting post-doctoral scholars and lab technicians. Please email <\/span><a href=\"mailto:ethylin.jabs@mssm.edu\"><span style=\"font-weight: 400\">ethylin.jabs@mssm.edu.<\/span><\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_text _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;]<\/p>\n<h2>Contact Us\u00a0<\/h2>\n<p><span style=\"font-weight: 400\">Ethylin Wang Jabs, MD<br \/><\/span><span style=\"font-weight: 400\">Lab telephone: 212-659-1529<br \/><\/span><span style=\"font-weight: 400\">E-mail: ethylin.jabs@mssm.edu<\/span><\/p>\n<h2>Facilities<b><br \/><\/b><\/h2>\n<p><span style=\"font-weight: 400\">Icahn School of Medicine<br \/>Department of Genetics and Genomic Sciences <br \/>1425 Madison Avenue<br \/><\/span><span style=\"font-weight: 400\">Room 14-76<br \/><\/span><span style=\"font-weight: 400\">New York, NY 10029<\/span><\/p>\n<p><span style=\"font-weight: 400\">Atran Berg Building<br \/><\/span><span style=\"font-weight: 400\">1428 Madison Avenue<br \/><\/span><span style=\"font-weight: 400\">First floor, AB 1-47<br \/><\/span><span style=\"font-weight: 400\">New York, NY 10029<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_row _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][et_pb_video src=&#8221;https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-content\/uploads\/sites\/181\/2022\/01\/86272239_637079370450745_9162121641390505984_n-2.mp4&#8243; _builder_version=&#8221;4.9.0&#8243; _module_preset=&#8221;default&#8221;][\/et_pb_video][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>WELCOME TO THE JABS LABThe Jabs lab studies human malformation disorders and birth defects applying genetic and genomic tools. We profile clinical samples, animal models, and cellular systems using a combination of next generation sequencing technologies and wet lab experimentation. Our goal is to elucidate the pathogenesis of these disorders to identify genes, mechanisms, and [&hellip;]<\/p>\n","protected":false},"author":165,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<a href=\"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-content\/uploads\/sites\/181\/2016\/06\/Website.jpg\"><img class=\"aligncenter wp-image-145 \" src=\"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-content\/uploads\/sites\/181\/2016\/06\/Website.jpg\" alt=\"Website\" width=\"489\" height=\"367\" \/><\/a>\r\n\r\nThe Ethylin Wang Jabs Laboratory is one of Mount Sinai\u2019s extensive array of top-notch facilities, translating advances in basic science into innovative patient care.\r\n\r\n\u00a0","_et_gb_content_width":"","footnotes":""},"class_list":["post-15","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/pages\/15","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/users\/165"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/comments?post=15"}],"version-history":[{"count":29,"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/pages\/15\/revisions"}],"predecessor-version":[{"id":579,"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/pages\/15\/revisions\/579"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/jabslab\/wp-json\/wp\/v2\/media?parent=15"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}