{"id":216,"date":"2018-05-31T14:46:04","date_gmt":"2018-05-31T14:46:04","guid":{"rendered":"http:\/\/labs.icahn.mssm.edu\/hubmacherlab\/?p=216"},"modified":"2018-05-31T14:46:04","modified_gmt":"2018-05-31T14:46:04","slug":"microgrant-from-rare-disease-foundation","status":"publish","type":"post","link":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/microgrant-from-rare-disease-foundation\/","title":{"rendered":"Microgrant from Rare Disease Foundation"},"content":{"rendered":"<p>The Hubmacher lab received a <a href=\"https:\/\/www.rarediseasefoundation.org\/research\/microgrants\/funded_microgrants\">microgrant<\/a> from the <a href=\"https:\/\/www.rarediseasefoundation.org\/\">Rare Disease Foundation<\/a> and the BC Children\u2019s Hospital Foundation in Canada. With this grant, we will study whether extracellular matrix function can be restored in cell lines derived from Marfan syndrome patients that harbor a premature stop-codon mutation in the fibrillin-1 (FBN1) gene. The results of our study may potentially delineate a personalized medicine approach in the treatment of Marfan syndrome that could be applicable to as much as\u00a015% of patients.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-218\" src=\"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-content\/uploads\/sites\/248\/2018\/05\/rare-disease-300x122.png\" alt=\"\" width=\"300\" height=\"122\" srcset=\"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-content\/uploads\/sites\/248\/2018\/05\/rare-disease-300x122.png 300w, https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-content\/uploads\/sites\/248\/2018\/05\/rare-disease.png 352w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\u00a0 <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-217\" src=\"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-content\/uploads\/sites\/248\/2018\/05\/bc-childrens-hospital-foundation-2017-300x224.png\" alt=\"\" width=\"300\" height=\"224\" srcset=\"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-content\/uploads\/sites\/248\/2018\/05\/bc-childrens-hospital-foundation-2017-300x224.png 300w, https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-content\/uploads\/sites\/248\/2018\/05\/bc-childrens-hospital-foundation-2017.png 540w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Hubmacher lab received a microgrant from the Rare Disease Foundation and the BC Children\u2019s Hospital Foundation in Canada. With this grant, we will study whether extracellular matrix function can be restored in cell lines derived from Marfan syndrome patients that harbor a premature stop-codon mutation in the fibrillin-1 (FBN1) gene. The results of our [&hellip;]<\/p>\n","protected":false},"author":258,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[11,7,10,4],"tags":[],"class_list":["post-216","post","type-post","status-publish","format-standard","hentry","category-grants","category-lab","category-news","category-research"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/posts\/216","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/users\/258"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/comments?post=216"}],"version-history":[{"count":2,"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/posts\/216\/revisions"}],"predecessor-version":[{"id":220,"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/posts\/216\/revisions\/220"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/media?parent=216"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/categories?post=216"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/hubmacherlab\/wp-json\/wp\/v2\/tags?post=216"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}