[et_pb_section fb_built=”1″ admin_label=”Hero Header2 Title Description – Section – Header – Fullwidth Slider” module_class=”hero-header2-title-description-slider-section1″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”0px||0px||false|false” locked=”on” collapsed=”on” global_colors_info=”{}”][et_pb_row module_id=”header2-title-description-slider-section1″ _builder_version=”4.16″ _module_preset=”default” width=”100%” max_width=”100%” custom_padding=”0px||0px||false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_slider use_text_overlay=”on” text_overlay_color=”rgba(255,255,255,0.8)” text_border_radius=”0px” arrows_custom_color=”#D80B8C” dot_nav_custom_color=”#ffffff” disabled_on=”on|on|on” _builder_version=”4.27.4″ _module_preset=”default” header_text_align=”left” header_text_color=”#000000″ header_font_size=”32px” header_line_height=”0.7em” body_text_align=”left” body_text_color=”#000000″ body_line_height=”1.2em” positioning=”none” horizontal_offset=”0px” width=”100%” height=”82.1vh” custom_padding_tablet=”” custom_padding_phone=”8%|8%|8%|8%|false|false” custom_padding_last_edited=”on|phone” custom_css_slide_description=”padding: 0;||position: relative;||top: 25%;||right: 0px;||left: 44.75%;||float: right !important;” custom_css_slide_active_controller=”background-color: #d80b8c;” box_shadow_style=”preset6″ box_shadow_vertical=”-300px” box_shadow_blur=”300px” box_shadow_spread=”-150px” box_shadow_color=”#000000″ disabled=”on” global_colors_info=”{}” custom_css_slide_description_last_edited=”on|desktop” custom_css_slide_description_tablet=”||” custom_css_slide_description_phone=”padding: 8% !important;”][et_pb_slide url_new_window=”on” use_text_overlay=”on” text_overlay_color=”rgba(255,255,255,0.8)” arrows_custom_color=”#D80B8C” dot_nav_custom_color=”#FFFFFF” text_border_radius=”0px” dot_nav_custom_color_last_edited=”off|desktop” _builder_version=”4.27.4″ _module_preset=”default” header_text_align=”left” header_text_color=”#000000″ header_font_size=”32px” header_line_height=”0.7em” body_font=”||||||||” body_text_align=”left” body_text_color=”#000000″ body_line_height=”1.2em” background_color=”#00AEEF” background_enable_color=”on” background_image=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2026\/01\/hu-lab-graphic.jpg” background_enable_image=”on” background_position=”top_center” custom_button=”on” button_text_size=”30px” button_text_color=”#000000″ button_bg_color=”RGBA(0,0,0,0)” button_border_radius=”0px” button_use_icon=”on” button_icon=”5||divi||400″ button_icon_color=”#000000″ button_on_hover=”off” button_alignment=”left” button_custom_margin=”0px||||false|false” button_custom_padding=”|50px|||false|false” text_orientation=”left” background_layout=”light” max_width=”60%” max_width_tablet=”” max_width_phone=”100%” max_width_last_edited=”on|phone” custom_padding_tablet=”” custom_padding_phone=”8%|8%|8%|8%|false|false” custom_padding_last_edited=”on|phone” link_option_url=”#” link_option_url_new_window=”on” header_font_size_tablet=”” header_font_size_phone=”22px” header_font_size_last_edited=”on|phone” body_font_size_tablet=”” body_font_size_phone=”14px” body_font_size_last_edited=”on|phone” global_colors_info=”{}” button_text_size__hover_enabled=”on|desktop” button_letter_spacing__hover_enabled=”off|desktop” button_border_radius__hover_enabled=”off|desktop” dot_nav_custom_color__hover_enabled=”off|desktop” custom_css_after_last_edited=”off|phone” custom_css_slide_title_last_edited=”off|desktop” custom_css_slide_description_last_edited=”on|desktop” custom_css_slide_description_phone=”padding: 8% !important;” button_text_size__hover=”30px” sticky_transition=”on”][\/et_pb_slide][\/et_pb_slider][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2026\/01\/hu-lab-graphic.jpg” title_text=”hu lab graphic” _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Two Column Title Over Text Next to Image – Section 5″ module_class=”section5_two_col_title_over_txt_next_to_img” _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”55px|||||” scroll_fade_enable=”on” locked=”off” collapsed=”on” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” admin_label=”5 (Module)” _builder_version=”4.9.0″ background_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” custom_padding=”6px||3px|||” global_module=”956″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_text_color=”#00AEEF” text_font_size=”24px” global_colors_info=”{}”]<\/p>\n
Our Research<\/strong><\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_text_color=”#00AEEF” text_font_size=”17px” header_font=”|700|||||||” header_text_color=”#00AEEF” header_font_size=”36px” module_alignment=”center” custom_padding=”1.1%||1.1%||true|false” global_colors_info=”{}”]<\/p>\n Our research focuses on understanding the initiation of sensory experiences, such as pain and itch, at the barrier surfaces of the skin and visceral organs. Additionally, we investigate how these signals, both from external and internal sources, converge in the spinal cord and are processed by specific neural circuits. Furthermore, we are interested in understanding how animals display distinct coping behaviors in response to somatic and visceral pain, how external and internal sensations are integrated to influence emotional states underlying behavior, and how dysregulated interoception can lead to psychopathologies.<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2022\/07\/ai-008.png” title_text=”ai-008″ _builder_version=”4.27.4″ _module_preset=”default” background_color=”#FFFFFF” custom_padding=”|77px||77px||” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Option2 Section19″ _builder_version=”4.27.4″ _module_preset=”default” background_color=”#FFFFFF” background_image=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2022\/07\/ai-008.png” background_size=”contain” background_position=”top_left” custom_padding=”13px||32px||false|false” scroll_fade_enable=”on” locked=”off” collapsed=”on” global_colors_info=”{}”][et_pb_row column_structure=”3_4,1_4″ _builder_version=”4.16″ _module_preset=”default” background_color=”#221F72″ module_alignment=”center” custom_padding=”80px|40px|80px|40px|false|false” global_colors_info=”{}”][et_pb_column type=”3_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_blurb title=”Our Approach” content_max_width=”768px” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|600|||||||” header_text_color=”#000000″ header_font_size=”20px” body_text_color=”#000000″ background_color=”#FFFFFF” custom_margin=”||||false|false” custom_padding=”40px|40px|40px|40px|false|false” custom_css_blurb_content=”\/*margin-left: 60px !important;||margin-right: 0px !important;*\/” box_shadow_style=”preset1″ global_colors_info=”{}”]<\/p>\n We employ multidisciplinary approaches, such as pharmacological, optogenetic, and chemogenetic manipulations, to study genetically defined and molecularly distinct neuronal populations. Additionally, we utilize a combination of neural tracing, in vivo imaging, electrophysiological recordings, molecular biology, and behavioral testing to gain insights into the molecular, cellular, and circuit mechanisms that underlie sensory processing in mice.<\/p>\n [\/et_pb_blurb][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Option2 Section16″ module_class=”Option2-Section16″ _builder_version=”4.27.4″ background_color=”#221F72″ background_enable_image=”off” width=”100%” custom_margin=”||||false|false” custom_padding=”4px|0px|0px|0px|false|false” mix_blend_mode=”multiply” bottom_divider_color=”#FFFFFF” bottom_divider_height=”150px” bottom_divider_flip=”horizontal” bottom_divider_arrangement=”above_content” scroll_fade_enable=”on” disabled=”on” locked=”off” collapsed=”on” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.27.4″ background_color=”#221F72″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” width=”100%” module_alignment=”center” min_height=”98.1%” height=”100%” max_height=”100%” custom_margin=”-6px|0px|0px|0px|false|false” custom_padding=”0px|0px|0px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ admin_label=”Image Column” _builder_version=”4.27.4″ background_position=”top_left” custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2026\/01\/project-1.png” title_text=”decoding itch signaling” _builder_version=”4.27.4″ _module_preset=”default” height=”525px” custom_padding=”22px|||179px||” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ admin_label=”Content Column” _builder_version=”4.16″ background_position=”top_left” custom_padding=”80px||40px||false|false” custom_padding_tablet=”0px|0px|40px|40px|false|false” custom_padding_phone=”||40px||false|false” custom_padding_last_edited=”on|tablet” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_text_color=”#FFFFFF” text_font_size=”24px” custom_margin=”-43px|||||” global_colors_info=”{}”]<\/p>\n Decoding itch\u00a0<\/span>signaling<\/span>\u00a0<\/span>mechanisms\u00a0<\/span>in the skin<\/span><\/span>\u00a0<\/span><\/strong><\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.27.4″ text_font=”||||||||” text_text_color=”#FFFFFF” text_font_size=”17px” text_line_height=”22px” header_font=”||||” header_text_align=”left” header_text_color=”#FFFFFF” header_2_text_align=”left” header_2_text_color=”#FFFFFF” header_3_text_align=”left” header_3_text_color=”#FFFFFF” header_4_text_align=”left” header_4_text_color=”#FFFFFF” header_5_text_align=”left” header_5_text_color=”#FFFFFF” header_6_text_align=”left” header_6_text_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width_tablet=”900px” max_width_phone=”” max_width_last_edited=”on|desktop” custom_padding=”|40px|||false|false” animation_direction=”top” global_colors_info=”{}”]<\/p>\n Both spontaneous and mechanical itch responses originate in the skin.\u00a0<\/span>Previous<\/span>\u00a0research has\u00a0<\/span>identified<\/span>\u00a0the Merkel cell-slowly adaptive Ab touch fiber complex as a key regulator of mechanical itch in normal conditions. However, in the context of aging or chronic itch associated with dry skin, the loss of Merkel cells removes the inhibition on mechanical itch, leading to the development of\u00a0<\/span>alloknesis<\/span>\u00a0(mechanical itch sensitization). Our studies have\u00a0<\/span>also\u00a0<\/span>shown that surviving Merkel cells in mice, following experimental dry skin treatment, can\u00a0<\/span>establish<\/span>\u00a0a functional connection with MrgprA3-expressing itch fibers and promote spontaneous itch. Notably, the mechanosensitive Piezo2 channels expressed by Merkel cells are essential for inhibiting mechanical itch and promoting spontaneous itch through the activation of slowly adaptive A<\/span><\/span>b<\/span><\/span>\u00a0fibers and C-<\/span>pruriceptors<\/span>, respectively. These findings have significantly contributed to our understanding of how Piezo2 channels and Merkel cells influence itch signaling in the skin. However, the mechanisms by which Merkel cells respond to tissue injury, skin inflammation, and aging, as well as the impact of these changes in Merkel cell biology on their interaction with touch and itch fibers in the skin, remain incompletely understood. Furthermore, we will investigate whether Merkel cells play a role in the development of skin inflammation, in addition to their involvement in itch signaling.<\/span><\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Option2 Section17″ module_class=”Option2-Section17″ _builder_version=”4.27.4″ background_color=”#EEEEEE” background_enable_image=”off” width=”100%” module_alignment=”center” custom_margin=”||||false|false” custom_padding=”40px|0px|40px|0px|false|false” mix_blend_mode=”multiply” bottom_divider_color=”#FFFFFF” bottom_divider_height=”150px” bottom_divider_flip=”horizontal” bottom_divider_arrangement=”above_content” scroll_fade_enable=”on” custom_css_main_element=”padding-bottom: 40px !important;” disabled=”on” locked=”off” collapsed=”on” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.16″ background_color=”RGBA(0,0,0,0)” background_size=”initial” background_position=”top_left” background_repeat=”repeat” module_alignment=”center” custom_margin=”0px|0px|0px|0px|false|false” custom_padding=”0px|0px|0px|0px|false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ background_position=”top_left” custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2026\/01\/project2.png” title_text=”Mechanisms of Interoception” show_bottom_space=”off” align=”center” disabled_on=”off|off|off” admin_label=”Image” _builder_version=”4.27.4″ module_alignment=”center” height=”536px” custom_padding=”3px|||||” animation_direction=”left” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ background_position=”top_left” global_colors_info=”{}”][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”24px” global_colors_info=”{}”]<\/p>\n Mechanisms of Interoception<\/strong><\/p>\n [\/et_pb_text][et_pb_text admin_label=”Body text” _builder_version=”4.27.4″ text_font=”||||||||” text_text_color=”#000000″ text_line_height=”22px” header_font=”||||” header_text_color=”#000000″ header_4_text_color=”#FFFFFF” header_5_text_color=”#FFFFFF” background_size=”initial” background_position=”top_left” background_repeat=”repeat” max_width=”90%” animation_direction=”top” global_colors_info=”{}”]<\/p>\n Sensory perceptions are\u00a0<\/span>initiated<\/span>\u00a0by a combination of external and internal cues, which play a crucial role in meeting our survival and psychological needs. The awareness of external stimuli, such as touch, sight, smell, sound, and taste, is known as exteroception. On the other hand,\u00a0<\/span>interoception<\/span>\u00a0refers to the\u00a0<\/span>perception<\/span>\u00a0of internal bodily states, including both unconscious processes like respiration and bowel movements, as well as conscious experiences like chest pain during a heart attack and intestinal cramps. Interoceptive signals are transmitted to the brain through two main pathways: the ascending\u00a0<\/span>viscerosensory<\/span>\u00a0pathway via the spinal cord, and the\u00a0<\/span>vagus<\/span>\u00a0sensory pathway through the nucleus tractus\u00a0<\/span>solitarii<\/span>\u00a0in the brainstem. However, our understanding of the\u00a0<\/span>CNS<\/span>\u00a0circuits responsible for processing interoceptive inputs from visceral organs is still limited. To address these gaps, we will\u00a0<\/span>utilize<\/span>\u00a0conventional genetic techniques and virally mediated intersectional genetics to\u00a0<\/span>identify<\/span>\u00a0<\/span>neural circuits<\/span>\u00a0that<\/span>\u00a0are essential for both the sensory discriminative and affective components of visceral pain.\u00a0<\/span><\/span>\u00a0<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”on|on|on” admin_label=”Option2 Section25 \u2013 Fullwidth Footer \u2013 Local” module_class=”footer-section” _builder_version=”4.16″ background_color=”#00AEEF” background_enable_image=”off” max_width=”100%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” module_alignment=”center” custom_margin=”0px|||176px|false|false” custom_padding=”3px|0px|0px|0px|false|false” animation_style=”slide” animation_direction=”bottom” animation_intensity_slide=”14%” animation_starting_opacity=”100%” disabled=”on” saved_tabs=”all” locked=”off” collapsed=”on” global_colors_info=”{}”][et_pb_row _builder_version=”4.16″ background_color=”RGBA(0,0,0,0)” background_color_gradient_direction=”38deg” module_alignment=”center” custom_margin=”|auto||147px||” locked=”off” collapsed=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_social_media_follow _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” text_orientation=”center” global_colors_info=”{}”][et_pb_social_media_follow_network social_network=”linkedin” url=”https:\/\/www.linkedin.com\/school\/icahnmountsinai\/%20″ use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” global_colors_info=”{}” follow_button=”off” url_new_window=”on”]linkedin[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”facebook” url=”https:\/\/www.facebook.com\/IcahnMountSinai” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” global_colors_info=”{}” follow_button=”off” url_new_window=”on”]facebook[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”twitter” url=”https:\/\/twitter.com\/icahnmountsinai” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” global_colors_info=”{}” follow_button=”off” url_new_window=”on”]twitter[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”youtube” url=”https:\/\/www.youtube.com\/user\/MountSinaiSchool” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” global_colors_info=”{}” follow_button=”off” url_new_window=”on”]youtube[\/et_pb_social_media_follow_network][et_pb_social_media_follow_network social_network=”instagram” url=”https:\/\/www.instagram.com\/icahnmountsinai\/” use_icon_font_size=”on” icon_font_size=”24px” _builder_version=”4.16″ _module_preset=”default” background_color=”RGBA(0,0,0,0)” background_enable_color=”on” global_colors_info=”{}” follow_button=”off” url_new_window=”on”]instagram[\/et_pb_social_media_follow_network][\/et_pb_social_media_follow][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_text_color=”#FFFFFF” text_font_size=”24px” global_colors_info=”{}”]<\/p>\n Contact Us<\/strong><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.16″ background_color=”RGBA(0,0,0,0)” background_color_gradient_direction=”38deg” module_alignment=”center” custom_margin=”|auto|-2px|auto||” custom_padding=”0px|||||” locked=”off” collapsed=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”22px” global_colors_info=”{}”]<\/p>\n Contact Us [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” locked=”off” global_colors_info=”{}”]<\/p>\n E-mail Phone [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”||||||||” text_text_color=”#FFFFFF” text_line_height=”1.25em” header_font=”||||||||” header_4_font=”|700||on|||||” header_4_font_size=”16px” header_4_letter_spacing=”1px” header_4_line_height=”1.5em” background_layout=”dark” locked=”off” global_colors_info=”{}”]<\/p>\n Lab Address <\/strong> Mailing Address <\/strong><\/p>\n Lab Name [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ fullwidth=”on” disabled_on=”on|on|on” admin_label=”Header Title Description – Section – Header – Fullwidth Slider ” module_id=”header-title-description-slider-section1″ _builder_version=”4.16″ _module_preset=”default” background_color=”rgba(0,174,239,0.09)” background_enable_color=”off” background_image=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2022\/07\/ai-002-1.jpg” parallax=”on” custom_padding=”||||false|false” bottom_divider_style=”ramp2″ bottom_divider_color=”#FFFFFF” bottom_divider_height=”11vw” disabled=”on” locked=”on” collapsed=”on” global_colors_info=”{}”][et_pb_fullwidth_slider arrows_custom_color=”#D80B8C” dot_nav_custom_color=”#D80B8C” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_slide heading=”One” _builder_version=”4.16″ _module_preset=”default” header_text_align=”left” body_text_align=”left” background_image=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2022\/07\/ai-002-1.jpg” background_enable_image=”on” text_orientation=”left” custom_padding=”|||80px|false|false” global_colors_info=”{}” sticky_transition=”on”]<\/p>\n Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n [\/et_pb_slide][et_pb_slide heading=”Two” _builder_version=”4.16″ _module_preset=”default” header_text_align=”left” body_text_align=”left” background_image=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2022\/07\/ai-002-1.jpg” background_enable_image=”on” text_orientation=”left” custom_padding=”|||80px|false|false” global_colors_info=”{}” sticky_transition=”on”]<\/p>\n Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n [\/et_pb_slide][et_pb_slide heading=”Three” _builder_version=”4.16″ _module_preset=”default” header_text_align=”left” body_text_align=”left” background_image=”https:\/\/labs.icahn.mssm.edu\/hongzhenhulab2\/wp-content\/uploads\/sites\/618\/2022\/07\/ai-002-1.jpg” background_enable_image=”on” text_orientation=”left” custom_padding=”|||80px|false|false” global_colors_info=”{}” sticky_transition=”on”]<\/p>\n Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n [\/et_pb_slide][\/et_pb_fullwidth_slider][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Our ResearchOur research focuses on understanding the initiation of sensory experiences, such as pain and itch, at the barrier surfaces of the skin and visceral organs. Additionally, we investigate how these signals, both from external and internal sources, converge in the spinal cord and are processed by specific neural circuits. 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