{"id":6,"date":"2020-05-28T10:44:51","date_gmt":"2020-05-28T10:44:51","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/harellab\/?page_id=6"},"modified":"2024-02-23T20:12:02","modified_gmt":"2024-02-23T20:12:02","slug":"home","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/harellab\/","title":{"rendered":"Home"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”Header” _builder_version=”4.9.0″ min_height=”1000px” custom_padding=”60px|||||” collapsed=”off”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.9.0″ min_height=”627.8px” custom_padding=”||0px|0|false|false”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”||178px|” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/harellab\/wp-content\/uploads\/sites\/355\/2020\/10\/logo.png” title_text=”logo” _builder_version=”4.9.0″ _module_preset=”default”][\/et_pb_image][et_pb_text _builder_version=”4.9.0″ text_font=”Roboto|300|||||||” text_line_height=”1.8em” header_font=”||||||||” header_font_size=”26px” width=”100%” custom_margin=”||35px” text_font_size_tablet=”” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” locked=”off”]<\/p>\n

Our goal is simple yet challenging:<\/strong><\/h2>\n

To improve voluntary movement of weakened parts of the body.<\/p>\n

To improve quality of life for people with spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS).<\/p>\n

[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/harellab\/our-research\/” button_text=”Learn about our research” _builder_version=”3.19.10″ custom_button=”on” button_text_size=”14px” button_text_color=”#ffffff” button_bg_color=”#267ff8″ button_border_width=”10px” button_border_color=”#267ff8″ button_letter_spacing=”1px” button_font=”Roboto|700||on|||||” button_use_icon=”off” background_layout=”dark” custom_margin=”-5px||” custom_padding=”8px|12px|8px|12px|true|true” locked=”off” button_bg_color__hover_enabled=”on” button_bg_color__hover=”#003fc9″ button_bg_enable_color__hover=”on”][\/et_pb_button][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/harellab\/wp-content\/uploads\/sites\/355\/2020\/07\/NeuroRehabilitation-Team-Photo.jpg” force_fullwidth=”on” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” admin_label=”Image” _builder_version=”4.9.0″ max_width_tablet=”400px” max_width_phone=”” max_width_last_edited=”on|desktop” min_height=”280.9px” custom_margin=”|-10vw||” custom_margin_tablet=”|0vw||” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” custom_padding=”|||0px||” border_radii=”|30px|7px|30px|30px” locked=”off”][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ prev_background_color=”#ffffff” admin_label=”Mission” _builder_version=”3.22″ background_color=”#1f2430″ custom_margin=”-189px|40px|0px|40px|false|true” custom_padding=”81px|||||” top_divider_style=”wave” collapsed=”off”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ animation_style=”fade” collapsed=”off”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”3.27.4″ text_font=”||||||||” header_font=”||||||||” header_2_font=”Roboto|700|||||||” header_2_font_size=”52px” header_2_line_height=”1.3em” header_4_font=”Poppins|600||on|||||” header_4_text_color=”rgba(255,255,255,0.4)” header_4_font_size=”11px” header_4_letter_spacing=”2px” header_4_line_height=”1.6em” background_layout=”dark” header_2_font_size_tablet=”32px” header_2_font_size_phone=”22px” header_2_font_size_last_edited=”on|phone” locked=”off”]<\/p>\n

Approach<\/h4>\n

[\/et_pb_text][et_pb_text _builder_version=”3.27.4″ text_font=”Roboto|300|||||||” text_text_color=”#ffffff” text_font_size=”17px” text_line_height=”1.8em” background_layout=”dark” custom_margin=”-20px|10px||” custom_padding=”|0px||” text_font_size_tablet=”” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” locked=”off”]<\/p>\n

We use the principle of \u2018Fire Together, Wire Together\u2019: When nearby nerves fire together repeatedly, connections between those nerves strengthen. The ability to change nerve circuit function is called \u201cneuroplasticity<\/u>\u201d. Neuroplasticity helps nerve circuits rewire and reconnect, leading to improved movement and control below the injury.\u00a0<\/p>\n

Our research interventions:<\/strong><\/p>\n

    \n
  • Electrical spinal stimulation<\/li>\n
  • Magnetic brain stimulation<\/li>\n
  • Targeted physical exercises<\/li>\n
  • Ischemic pre-conditioning<\/li>\n
  • New uses for old drugs<\/li>\n
  • And more\u2026<\/li>\n<\/ul>\n

    Our cutting-edge technologies:<\/strong><\/p>\n

      \n
    • Transcranial magnetic stimulation (TMS)<\/li>\n
    • Electroencephalography (EEG)<\/li>\n
    • Electromyography (EMG)<\/li>\n
    • Infrared-guided neuronavigation<\/li>\n
    • Computerized posturography<\/li>\n
    • And MUCH more\u2026<\/li>\n<\/ul>\n

      [\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”3.27.4″ text_font=”||||||||” header_font=”||||||||” header_2_font=”Roboto|700|||||||” header_2_font_size=”52px” header_2_line_height=”1.3em” header_4_font=”Poppins|600||on|||||” header_4_text_color=”rgba(255,255,255,0.4)” header_4_font_size=”11px” header_4_letter_spacing=”2px” header_4_line_height=”1.6em” background_layout=”dark” header_2_font_size_tablet=”32px” header_2_font_size_phone=”22px” header_2_font_size_last_edited=”on|phone” locked=”off”]<\/p>\n

      Our Values<\/h4>\n

      [\/et_pb_text][et_pb_text _builder_version=”3.27.4″ text_font=”Roboto|300|||||||” text_text_color=”#ffffff” text_font_size=”17px” text_line_height=”1.8em” background_layout=”dark” custom_margin=”-20px||” text_font_size_tablet=”” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” locked=”off”]<\/p>\n

        \n
      • Communicate openly with people in the community with SCI, ALS, and other disorders.<\/li>\n<\/ul>\n
          \n
        • Share data and collaborate openly with other researchers.<\/li>\n<\/ul>\n
            \n
          • Continually foster the recruitment and development of new and young researchers.<\/li>\n<\/ul>\n

            [\/et_pb_text][et_pb_text _builder_version=”3.27.4″ text_font=”Roboto|300|||||||” text_text_color=”#ffffff” text_font_size=”17px” text_line_height=”1.8em” background_layout=”dark” custom_margin=”-20px||” text_font_size_tablet=”” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” locked=”off”]<\/p>\n

            Our group is part of the James J. Peters VA Spinal Cord Damage Research Center. The Center has a thriving mix of senior and junior research faculty and staff, spanning specialties from neurology, rehabilitation, physiology, endocrinology, gastroenterology, engineering, and molecular science. <\/p>\n

            <\/strong><\/p>\n

            We are open to enrollment of Veterans AND non-Veterans for our clinical research studies.<\/strong><\/span>
            \n[\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/harellab\/about-us\/” button_text=”Meet our team” _builder_version=”3.19.10″ custom_button=”on” button_text_size=”14px” button_text_color=”#ffffff” button_bg_color=”#267ff8″ button_border_width=”10px” button_border_color=”#267ff8″ button_letter_spacing=”1px” button_font=”Roboto|700||on|||||” button_use_icon=”off” background_layout=”dark” custom_margin=”55px||” custom_padding=”8px|12px|8px|12px|true|true” locked=”off” button_bg_color__hover_enabled=”on” button_bg_color__hover=”#003fc9″ button_bg_enable_color__hover=”on”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Feature” _builder_version=”3.22″ custom_margin=”|40px||40px”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ animation_style=”fade”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/harellab\/wp-content\/uploads\/sites\/355\/2022\/03\/2022.03.17.ElectricalStimulationSCI_NHtalk.png” alt=”Electrical spinal stimulation in people with SCI” title_text=”2022.03.17.ElectricalStimulationSCI_NHtalk” url=”https:\/\/youtu.be\/Zr3LrrBhfe8″ align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.9.0″ custom_margin=”|||0px” custom_margin_tablet=”|||0vw” custom_margin_phone=”” custom_margin_last_edited=”on|tablet” border_radii=”|20px||20px|” border_width_all=”4px” border_color_all=”#f5f7fa”][\/et_pb_image][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.9.0″ text_font=”||||||||” header_font=”||||||||” header_text_color=”#1f2430″ header_2_font=”Roboto|700|||||||” header_2_text_color=”#1f2430″ header_2_font_size=”52px” header_2_line_height=”1.3em” header_4_font=”Poppins|600||on|||||” header_4_text_color=”rgba(31,36,48,0.59)” header_4_font_size=”11px” header_4_letter_spacing=”2px” header_4_line_height=”1.6em” background_color=”rgba(0,8,84,0.47)” background_layout=”dark” custom_margin=”0px|-70px||-20px|false|false” custom_padding=”2px||0px|4px|false|false” header_2_font_size_tablet=”32px” header_2_font_size_phone=”22px” header_2_font_size_last_edited=”on|phone” border_radii=”on|5px|5px|5px|5px” locked=”off”]<\/p>\n

            Webinar<\/h4>\n

            Electrical Spinal Cord Stimulation in People with SCI<\/h3>\n

            [\/et_pb_text][et_pb_text _builder_version=”4.9.0″ text_font=”Roboto|300|||||||” text_text_color=”#51596c” text_font_size=”17px” text_line_height=”1.8em” background_layout=”dark” custom_margin=”-20px|-70px||-20px” text_font_size_tablet=”” text_font_size_phone=”14px” text_font_size_last_edited=”on|desktop” locked=”off”]<\/p>\n

            Thursday, March 17 at 4:00 PM EST<\/p>\n

            Missed the virtual presentation with Dr. Noam Harel that addressed the topic of electrical spinal cord stimulation in people with SCI?<\/p>\n

            Watch it now on our YouTube Channel<\/p>\n

            [\/et_pb_text][et_pb_button button_url=”https:\/\/labs.icahn.mssm.edu\/harellab\/publications\/” button_text=”View our publications” _builder_version=”4.9.0″ custom_button=”on” button_text_size=”14px” button_text_color=”#ffffff” button_bg_color=”RGBA(0,8,84,0.47)” button_border_width=”10px” button_border_color=”RGBA(0,0,0,0)” button_letter_spacing=”1px” button_font=”Roboto|700||on|||||” button_use_icon=”off” background_layout=”dark” custom_margin=”55px||” custom_padding=”8px|12px|8px|12px|true|true” locked=”off” button_bg_color__hover_enabled=”on” button_bg_color__hover=”#003fc9″ button_bg_enable_color__hover=”on”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

            Our goal is simple yet challenging: To improve voluntary movement of weakened parts of the body. To improve quality of life for people with spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS).Approach We use the principle of \u2018Fire Together, Wire Together\u2019: When nearby nerves fire together repeatedly, connections between those nerves strengthen. The ability […]<\/p>\n","protected":false},"author":403,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"

            Individuals with SCI usually have residual nerve connections, even if they do not have conscious control over these neural pathways. We are utilizing sophisticated approaches to identify these spared nerve pathways. To strengthen spared nerve pathways, different combinations of physical exercises, magnetic stimulation, and electrical stimulation are being employed in an effort to improve function.<\/p>","_et_gb_content_width":"","footnotes":""},"class_list":["post-6","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/labs.icahn.mssm.edu\/harellab\/wp-json\/wp\/v2\/pages\/6","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.icahn.mssm.edu\/harellab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.icahn.mssm.edu\/harellab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/harellab\/wp-json\/wp\/v2\/users\/403"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.icahn.mssm.edu\/harellab\/wp-json\/wp\/v2\/comments?post=6"}],"version-history":[{"count":96,"href":"https:\/\/labs.icahn.mssm.edu\/harellab\/wp-json\/wp\/v2\/pages\/6\/revisions"}],"predecessor-version":[{"id":2345,"href":"https:\/\/labs.icahn.mssm.edu\/harellab\/wp-json\/wp\/v2\/pages\/6\/revisions\/2345"}],"wp:attachment":[{"href":"https:\/\/labs.icahn.mssm.edu\/harellab\/wp-json\/wp\/v2\/media?parent=6"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}