{"id":2230,"date":"2023-12-06T17:43:43","date_gmt":"2023-12-06T17:43:43","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/harellab\/?page_id=2230"},"modified":"2026-03-25T15:30:24","modified_gmt":"2026-03-25T15:30:24","slug":"the-role-of-androgens-in-neurophysiological-and-autonomic-function-in-male-veterans","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/harellab\/the-role-of-androgens-in-neurophysiological-and-autonomic-function-in-male-veterans\/","title":{"rendered":"The Role of Androgens in Neurophysiological and Autonomic Function in Male Veterans with Spinal Cord Injury"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.16″ custom_margin=”40px|40px|50px|40px|false|true” custom_padding=”0px||0px||true” border_radii=”|||60px|” global_colors_info=”{}”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”3_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.16″ text_font=”Roboto|300|||||||” text_text_color=”#1f2430″ text_font_size=”22px” text_line_height=”1.5em” header_font=”||||||||” header_text_color=”#1f2430″ header_2_font=”Roboto|700|||||||” header_2_text_color=”#1f2430″ header_2_font_size=”62px” custom_margin=”|-225px||” custom_padding=”10%|0px||” animation_style=”fade” global_colors_info=”{}”]<\/p>\n

The Role of Androgens in Neurophysiological and Autonomic Function in Male Veterans with Spinal Cord Injury<\/h2>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ prev_background_color=”#ffffff” _builder_version=”4.16″ background_color=”#f5f7fa” custom_margin=”|40px|40px|40px||true” top_divider_style=”wave” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.4″ text_font=”Roboto|300|||||||” text_text_color=”#51596c” text_font_size=”20px” text_line_height=”1.6em” header_font=”Roboto|700|||||||” header_text_color=”#1f2430″ header_font_size=”48px” header_2_font=”Roboto|700|||||||” header_2_font_size=”48px” header_2_line_height=”1.4em” header_3_font=”Roboto|700|||||||” header_3_text_color=”#1f2430″ header_3_font_size=”48px” header_3_line_height=”1.5em” custom_margin=”30px||30px||true” animation_style=”fade” hover_enabled=”0″ text_font_size_tablet=”16px” text_font_size_phone=”14px” text_font_size_last_edited=”on|phone” header_2_font_size_tablet=”30px” header_2_font_size_phone=”22px” header_2_font_size_last_edited=”on|phone” global_colors_info=”{}” header_font_size__hover=”30px” header_font_size__hover_enabled=”30px” header_letter_spacing__hover=”0px” header_letter_spacing__hover_enabled=”0px” header_text_shadow_style__hover=”none” header_text_shadow_style__hover_enabled=”none” header_text_shadow_color__hover=”rgba(0,0,0,0.4)” header_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” text_font_size__hover=”14px” text_font_size__hover_enabled=”14px” text_letter_spacing__hover=”0px” text_letter_spacing__hover_enabled=”0px” text_line_height__hover=”1.7em” text_line_height__hover_enabled=”1.7em” text_text_shadow_style__hover=”none” text_text_shadow_style__hover_enabled=”none” text_text_shadow_color__hover=”rgba(0,0,0,0.4)” text_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” link_font_size__hover=”14px” link_font_size__hover_enabled=”14px” link_letter_spacing__hover=”0px” link_letter_spacing__hover_enabled=”0px” link_line_height__hover=”1em” link_line_height__hover_enabled=”1em” link_text_shadow_style__hover=”none” link_text_shadow_style__hover_enabled=”none” link_text_shadow_color__hover=”rgba(0,0,0,0.4)” link_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” ul_font_size__hover=”14px” ul_font_size__hover_enabled=”14px” ul_letter_spacing__hover=”0px” ul_letter_spacing__hover_enabled=”0px” ul_line_height__hover=”1em” ul_line_height__hover_enabled=”1em” ul_text_shadow_style__hover=”none” ul_text_shadow_style__hover_enabled=”none” ul_text_shadow_color__hover=”rgba(0,0,0,0.4)” ul_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” ol_font_size__hover=”14px” ol_font_size__hover_enabled=”14px” ol_letter_spacing__hover=”0px” ol_letter_spacing__hover_enabled=”0px” ol_line_height__hover=”1em” ol_line_height__hover_enabled=”1em” ol_text_shadow_style__hover=”none” ol_text_shadow_style__hover_enabled=”none” ol_text_shadow_color__hover=”rgba(0,0,0,0.4)” ol_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” quote_font_size__hover=”14px” quote_font_size__hover_enabled=”14px” quote_letter_spacing__hover=”0px” quote_letter_spacing__hover_enabled=”0px” quote_line_height__hover=”1em” quote_line_height__hover_enabled=”1em” quote_text_shadow_style__hover=”none” quote_text_shadow_style__hover_enabled=”none” quote_text_shadow_color__hover=”rgba(0,0,0,0.4)” quote_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” text_orientation__hover=”left” text_orientation__hover_enabled=”left” background_layout__hover=”light” background_layout__hover_enabled=”light” max_width__hover=”100%” max_width__hover_enabled=”100%” sticky_enabled=”0″]<\/p>\n

Background<\/h2>\n
\n

This study focuses on the immediate (i.e., 30 minutes after a single dose) and short-term (i.e., one month of daily administration) effects of intranasal testosterone replacement therapy (iTRT) on restoration of central nervous system (CNS) excitability and cardiovascular function in men with chronic spinal cord injury (SCI) and Amyotrophic lateral sclerosis (ALS) compared to uninjured volunteers. Additionally, we will examine the relationships among testosterone concentrations, neural function, and cardiovascular function. The iTRT has already gained U.S. Food and Drug Administration (FDA) approval.<\/span><\/p>\n<\/div>\n

 <\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/labs.icahn.mssm.edu\/harellab\/wp-content\/uploads\/sites\/355\/2023\/11\/natesto.png” alt=”Brain Stimulation with Neuronavigation” title_text=”natesto” align=”right” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ max_width=”112%” module_alignment=”right” custom_margin=”40px|0px||” custom_padding=”0px|0px|0px||true” animation_style=”fade” custom_css_before=”z-index: 99;||” custom_css_main_element=”z-index: 99;||” custom_css_after=”z-index: 99;||” border_radii=”||60px|60px|60px” box_shadow_style=”preset1″ box_shadow_color=”rgba(0,0,0,0.13)” global_colors_info=”{}”]
\n[\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_accordion open_toggle_text_color=”#267ff8″ open_toggle_background_color=”#ffffff” closed_toggle_text_color=”#1f2430″ closed_toggle_background_color=”#ffffff” icon_color=”#267ff8″ _builder_version=”4.27.4″ toggle_font=”Roboto|500|||||||” body_font=”Roboto|300|||||||” body_text_color=”#51596c” global_colors_info=”{}”][et_pb_accordion_item title=”Eligibility Criteria (summary)” open=”on” _builder_version=”4.27.4″ global_colors_info=”{}”]<\/p>\n