
{"id":3794,"date":"2023-03-23T16:07:53","date_gmt":"2023-03-23T20:07:53","guid":{"rendered":"https:\/\/labs.icahn.mssm.edu\/design\/?page_id=3794"},"modified":"2025-10-02T10:53:57","modified_gmt":"2025-10-02T14:53:57","slug":"option-two","status":"publish","type":"page","link":"https:\/\/labs.icahn.mssm.edu\/gulatilab\/","title":{"rendered":"Home"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Hero Header2 Title Description &#8211; Section &#8211; Header &#8211; Fullwidth Slider&#8221; module_class=&#8221;hero-header2-title-description-slider-section1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row module_id=&#8221;header2-title-description-slider-section1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; max_width=&#8221;100%&#8221; 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_builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.6em&#8221; header_text_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;|0px|||false|false&#8221; custom_padding=&#8221;|0px|||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Malesuada fames ac turpis egestas sed tempus urna. In iaculis nunc sed augue lacus. Accumsan sit amet nulla facilisi morbi. Sit amet consectetur adipiscing elit pellentesque habitant morbi. Elementum nibh tellus molestie nunc non. Sed arcu non odio euismod lacinia at quis risus sed. Vulputate dignissim suspendisse in est ante in nibh.<\/p>\n<p>Amet venenatis urna cursus eget nunc scelerisque viverra mauris. Varius duis at consectetur lorem donec massa sapien. Fermentum iaculis eu non diam phasellus vestibulum lorem sed risus. Tempor id eu nisl nunc mi ipsum faucibus. Dictumst quisque sagittis purus sit amet volutpat. Sapien et ligula ullamcorper malesuada proin.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Option2 Section16&#8243; module_class=&#8221;Option2-Section16&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#221F72&#8243; background_enable_image=&#8221;off&#8221; width=&#8221;100%&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; mix_blend_mode=&#8221;multiply&#8221; bottom_divider_color=&#8221;#FFFFFF&#8221; bottom_divider_height=&#8221;150px&#8221; bottom_divider_flip=&#8221;horizontal&#8221; bottom_divider_arrangement=&#8221;above_content&#8221; disabled=&#8221;on&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#221F72&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; width=&#8221;100%&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;100%&#8221; height=&#8221;100%&#8221; max_height=&#8221;100%&#8221; custom_margin=&#8221;0px|0px|0px|0px|false|false&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; admin_label=&#8221;Image Column&#8221; _builder_version=&#8221;4.16&#8243; background_position=&#8221;top_left&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/labs.icahn.mssm.edu\/gulatilab-2\/wp-content\/uploads\/sites\/579\/2022\/08\/2021-Hero-Shot-2-smallest-scaled-.jpg&#8221; title_text=&#8221;2021-Hero-Shot-2-smallest-scaled-&#8221; show_bottom_space=&#8221;off&#8221; align=&#8221;center&#8221; force_fullwidth=&#8221;on&#8221; disabled_on=&#8221;off|off|off&#8221; module_class=&#8221;EtPbModule-Image_fullHeightImageColumn&#8221; _builder_version=&#8221;4.27.4&#8243; min_height=&#8221;100%&#8221; height=&#8221;100%&#8221; max_height=&#8221;100%&#8221; custom_margin=&#8221;0px|0px|0px|0px|false|false&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; animation_direction=&#8221;left&#8221; custom_css_main_element=&#8221;height: 100%;||\/*object-fit: cover;*\/&#8221; always_center_on_mobile=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; admin_label=&#8221;Content Column&#8221; _builder_version=&#8221;4.16&#8243; background_position=&#8221;top_left&#8221; custom_padding=&#8221;80px||40px||false|false&#8221; custom_padding_tablet=&#8221;0px|0px|40px|40px|false|false&#8221; custom_padding_phone=&#8221;||40px||false|false&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;22px&#8221; header_font=&#8221;||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_3_text_align=&#8221;left&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; header_4_text_align=&#8221;left&#8221; header_4_text_color=&#8221;#FFFFFF&#8221; header_5_text_align=&#8221;left&#8221; header_5_text_color=&#8221;#FFFFFF&#8221; header_6_text_align=&#8221;left&#8221; header_6_text_color=&#8221;#FFFFFF&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; max_width_tablet=&#8221;900px&#8221; max_width_phone=&#8221;&#8221; max_width_last_edited=&#8221;on|desktop&#8221; custom_padding=&#8221;|40px|||false|false&#8221; animation_direction=&#8221;top&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><strong>Lorem ipsum dolor sit amet<\/strong><\/h2>\n<p>Stem cells and their immediate environment, also called stem cell niche, are critical for the growth and continuous renewal of our organs, and are also key for new growth and repair during regeneration. Unlocking the secrets of how specialized niche cells operate to activate stem cells and progenitors holds great promise for regenerative medicine.<\/p>\n<p>Our laboratory aims to answer these fundamental questions in stem cell biology by utilizing the hair follicle mini-organ as a powerful model system. Deciphering how niche cells govern stem cell and progenitor functions in the hair follicle will also provide a rational basis for developing hair regenerative therapies.<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/labs.icahn.mssm.edu\/design\/option1-research&#8221; button_text=&#8221;Find Out More &#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#d80b8c&#8221; button_bg_color=&#8221;#FFFFFF&#8221; button_border_radius=&#8221;0px&#8221; button_on_hover=&#8221;off&#8221; custom_padding=&#8221;15px|50px|15px||false|false&#8221; hover_transition_duration=&#8221;0ms&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Two Column Title Over Text Next to Image &#8211; Section 5&#8243; module_class=&#8221;section5_two_col_title_over_txt_next_to_img&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; scroll_fade_enable=&#8221;on&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; admin_label=&#8221;5 (Module)&#8221; _builder_version=&#8221;4.9.0&#8243; background_color=&#8221;#FFFFFF&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;10px|auto||auto||&#8221; custom_padding=&#8221;6px||3px|||&#8221; global_module=&#8221;956&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#00AEEF&#8221; text_font_size=&#8221;32px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>Our Mission<\/strong><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#00AEEF&#8221; header_font=&#8221;|700|||||||&#8221; header_text_color=&#8221;#00AEEF&#8221; header_font_size=&#8221;36px&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;-26px|||||&#8221; custom_padding=&#8221;5.7%||5.7%||true|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>The immune system plays a pivotal role in the pathogenesis of most of the skin diseases and drug rashes that dermatologists encounter daily in clinical practice. However, the immune system can also be harnessed to help fight skin cancers, benign skin tumors, and cancers outside of the skin.\u00a0<u>Oncodermatology<\/u>\u00a0is an emerging subfield within dermatology that is concerned with treating skin toxicities that result from various anti-cancer therapies.\u00a0<u>Immunotherapy<\/u>\u00a0involves activating the immune system to attack tumor cells, and is becoming one of the primary treatment modalities for skin and other cancers. Human skin serves as a uniquely accessible model for the study of the immune system in the setting of cancer.<\/p>\n<p>Why particular skin toxicities occur in certain cancer patients during their therapies is unknown, and the appropriate methods to treat these reactions while still maintaining anti-tumor efficacy represent major clinical needs. Increased understanding of the immunology underlying these toxicities offers an untapped source of potential therapeutic strategies. Our ultimate goal is to improve human health through a deeper understanding of the relationship between the immune system and cancer in the skin.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/labs.icahn.mssm.edu\/gulatilab-2\/wp-content\/uploads\/sites\/579\/2022\/07\/ai-008.png&#8221; title_text=&#8221;ai-008&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Option2 Section17&#8243; module_class=&#8221;Option2-Section17&#8243; _builder_version=&#8221;4.27.4&#8243; background_color=&#8221;#EEEEEE&#8221; background_enable_image=&#8221;off&#8221; width=&#8221;100%&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;40px|0px|40px|0px|false|false&#8221; mix_blend_mode=&#8221;multiply&#8221; bottom_divider_color=&#8221;#FFFFFF&#8221; bottom_divider_height=&#8221;150px&#8221; bottom_divider_flip=&#8221;horizontal&#8221; bottom_divider_arrangement=&#8221;above_content&#8221; scroll_fade_enable=&#8221;on&#8221; custom_css_main_element=&#8221;padding-bottom: 40px !important;&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;0px|0px|0px|0px|false|false&#8221; custom_padding=&#8221;0px|0px|40px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; background_position=&#8221;top_left&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_image src=&#8221;https:\/\/labs.icahn.mssm.edu\/gulatilab-2\/wp-content\/uploads\/sites\/579\/2025\/09\/Dr.-Gulati-Nicholas-2023-scaled.jpg&#8221; title_text=&#8221;Dr. Gulati Nicholas-2023&#8243; show_bottom_space=&#8221;off&#8221; align=&#8221;center&#8221; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Image&#8221; _builder_version=&#8221;4.27.4&#8243; module_alignment=&#8221;center&#8221; custom_padding=&#8221;|100px||||&#8221; animation_direction=&#8221;left&#8221; always_center_on_mobile=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.16&#8243; background_position=&#8221;top_left&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Title Text&#8221; module_class=&#8221;Option2-Section17-TextModule_title Option2-Section17-TextModule_title_1110&#8243; _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_line_height=&#8221;22px&#8221; header_font=&#8221;||||&#8221; header_text_color=&#8221;#000000&#8243; header_4_text_color=&#8221;#000000&#8243; header_5_text_color=&#8221;#000000&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; max_width=&#8221;90%&#8221; custom_margin=&#8221;5px||16px||false|false&#8221; animation_direction=&#8221;top&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><strong>Clinical Research and Focus<\/strong><\/h2>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Body text&#8221; _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#000000&#8243; text_line_height=&#8221;22px&#8221; header_font=&#8221;||||&#8221; header_text_color=&#8221;#000000&#8243; header_4_text_color=&#8221;#FFFFFF&#8221; header_5_text_color=&#8221;#FFFFFF&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; max_width=&#8221;90%&#8221; animation_direction=&#8221;top&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Dr. Gulati is a board-certified dermatologist with expertise in melanoma and other skin cancers. His PhD thesis was on topical melanoma immunotherapy, and he has advanced training in state-of-the-art methods for early detection of skin cancers. He also has a particular interest in oncodermatology, the management of skin conditions that result from cancer treatments.<\/p>\n<p>Clinical Focus:<\/p>\n<ul>\n<li class=\"print:hidden md:mr-6 mr-3\">Actinic Keratosis<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Atypical Nevus<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Biopsy<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Cryotherapy<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Dysplastic Nevus<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Hemangioma<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Melanoma<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Moles<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Rash<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Seborrheic Keratosis<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Skin Biopsy<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Skin Cancer<\/li>\n<li class=\"print:hidden md:mr-6 mr-3\">Squamous Cell<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;https:\/\/profiles.mountsinai.org\/nicholas-david-gulati&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;Find Out More &#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;#00AEEF&#8221; button_border_radius=&#8221;0px&#8221; button_on_hover=&#8221;off&#8221; custom_padding=&#8221;15px|50px|15px||false|false&#8221; hover_transition_duration=&#8221;0ms&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Option2 Section18&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#00AEEF&#8221; disabled=&#8221;on&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(0,174,239,0.8)&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;Lorem Ipsum&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_level=&#8221;h2&#8243; header_font=&#8221;|600|||||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;30px&#8221; body_text_align=&#8221;left&#8221; body_text_color=&#8221;#FFFFFF&#8221; body_font_size=&#8221;14px&#8221; body_line_height=&#8221;1.4em&#8221; background_color=&#8221;rgba(0,110,150,0.5)&#8221; background_layout=&#8221;dark&#8221; custom_padding=&#8221;80px|40px|80px|40px|false|false&#8221; custom_css_blurb_title=&#8221;padding-bottom: 30px;&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Amet venenatis urna cursus eget nunc scelerisque viverra mauris. Varius duis at consectetur lorem donec massa sapien. Fermentum iaculis eu non diam phasellus vestibulum lorem sed risus. Tempor id eu nisl nunc mi ipsum faucibus. Dictumst quisque sagittis purus sit amet volutpat. Sapien et ligula ullamcorper malesuada proin. Risus commodo viverra maecenas accumsan lacus vel facilisis volutpat est.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;Lorem Ipsum&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; header_level=&#8221;h2&#8243; header_font=&#8221;|600|||||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;30px&#8221; body_text_align=&#8221;left&#8221; body_text_color=&#8221;#FFFFFF&#8221; body_font_size=&#8221;14px&#8221; body_line_height=&#8221;1.4em&#8221; background_color=&#8221;rgba(0,110,150,0.5)&#8221; background_layout=&#8221;dark&#8221; custom_padding=&#8221;80px|40px|80px|40px|false|false&#8221; custom_css_blurb_title=&#8221;padding-bottom: 30px;&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Amet venenatis urna cursus eget nunc scelerisque viverra mauris. Varius duis at consectetur lorem donec massa sapien. Fermentum iaculis eu non diam phasellus vestibulum lorem sed risus. Tempor id eu nisl nunc mi ipsum faucibus. Dictumst quisque sagittis purus sit amet volutpat. Sapien et ligula ullamcorper malesuada proin. Risus commodo viverra maecenas accumsan lacus vel facilisis volutpat est.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;Lorem Ipsum&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; header_level=&#8221;h2&#8243; header_font=&#8221;|600|||||||&#8221; header_text_align=&#8221;left&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;30px&#8221; body_text_align=&#8221;left&#8221; body_text_color=&#8221;#FFFFFF&#8221; body_font_size=&#8221;14px&#8221; body_line_height=&#8221;1.4em&#8221; background_color=&#8221;rgba(0,110,150,0.5)&#8221; background_layout=&#8221;dark&#8221; custom_padding=&#8221;80px|40px|80px|40px|false|false&#8221; custom_css_blurb_title=&#8221;padding-bottom: 30px;&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Amet venenatis urna cursus eget nunc scelerisque viverra mauris. Varius duis at consectetur lorem donec massa sapien. Fermentum iaculis eu non diam phasellus vestibulum lorem sed risus. Tempor id eu nisl nunc mi ipsum faucibus. Dictumst quisque sagittis purus sit amet volutpat. Sapien et ligula ullamcorper malesuada proin. Risus commodo viverra maecenas accumsan lacus vel facilisis volutpat est.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Option2 Section19&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/gulatilab-2\/wp-content\/uploads\/sites\/579\/2022\/07\/ai-008.png&#8221; background_size=&#8221;contain&#8221; background_position=&#8221;top_left&#8221; custom_padding=&#8221;100px||100px||false|false&#8221; scroll_fade_enable=&#8221;on&#8221; locked=&#8221;off&#8221; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;3_4,1_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#221F72&#8243; module_alignment=&#8221;center&#8221; custom_padding=&#8221;80px|40px|80px|40px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;3_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb content_max_width=&#8221;768px&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;|600|||||||&#8221; header_text_color=&#8221;#000000&#8243; body_text_color=&#8221;#000000&#8243; background_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;40px|40px|40px|40px|false|false&#8221; custom_css_blurb_content=&#8221;\/*margin-left: 60px !important;||margin-right: 0px !important;*\/&#8221; box_shadow_style=&#8221;preset1&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><strong>Our Approach<\/strong><\/h2>\n<p>We seek to obtain a deep understanding of skin immune reactions in the setting of both systemic and topical immunotherapies. We accomplish this by leveraging single-cell and spatial multi-omic approaches applied directly to patient skin tissue. Through techniques such as\u00a0<b>single-cell RNA-sequencing (scRNA-seq)<\/b>, we<b>\u00a0<\/b>obtain a detailed view of gene expression profiles in various cell populations found within the skin. Also, to more precisely map positional relationships of different cell types within skin tissue, we employ\u00a0<b>spatial transcriptomics (ST)<\/b>\u00a0and\u00a0<b>multiplexed ion beam imaging (MIBI)<\/b>. In addition, we study patient blood samples through\u00a0<b>spectral flow cytometry<\/b>\u00a0and\u00a0<b>proteomics\u00a0<\/b>to correlate skin immune profiles with those found systemically. We were the first to combine these modalities to comprehensively profile patients receiving immunotherapy.<\/p>\n<p>Our lab has an active clinical trials component, so we are able to treat our patients with novel therapeutics and repeat profiling after the treatment course. This ensures a robust bench-to-bedside approach that allows us to directly apply what we learn in the lab to patient care.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; custom_margin=&#8221;-100px|||||&#8221;][et_pb_row _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#00AEEF&#8221; text_font_size=&#8221;26px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>Our Affiliations<\/strong><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; text_font_size=&#8221;20px&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<div class=\"et_pb_module et_pb_text et_pb_text_7  et_pb_text_align_left et_pb_bg_layout_light\">\n<div class=\"et_pb_text_inner\">\n<p><a href=\"https:\/\/icahn.mssm.edu\/about\/departments\/dermatology\">Derpartment of Dermatology<\/a>\u00a0 \u00a0 \u00a0 | \u00a0 \u00a0 \u00a0<a href=\"https:\/\/icahn.mssm.edu\/research\/tisch\">Tisch Cancer Institute<\/a><\/p>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Option2 Section20&#8243; module_class=&#8221;Option2-Section20&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#00AEEF&#8221; background_enable_image=&#8221;off&#8221; width=&#8221;100%&#8221; module_alignment=&#8221;center&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; mix_blend_mode=&#8221;multiply&#8221; bottom_divider_color=&#8221;#FFFFFF&#8221; bottom_divider_height=&#8221;150px&#8221; bottom_divider_flip=&#8221;horizontal&#8221; bottom_divider_arrangement=&#8221;above_content&#8221; disabled=&#8221;on&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;RGBA(0,0,0,0)&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; width=&#8221;100%&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;100%&#8221; height=&#8221;100%&#8221; max_height=&#8221;100%&#8221; custom_margin=&#8221;0px|0px|0px|0px|false|false&#8221; custom_padding=&#8221;0px|0px|0px|0px|false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; admin_label=&#8221;Content Column&#8221; _builder_version=&#8221;4.16&#8243; background_position=&#8221;top_left&#8221; custom_padding=&#8221;80px||40px||false|false&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text module_class=&#8221;Option2-Section20-TextModule Option2-Section20-TextModule_981-1400&#8243; _builder_version=&#8221;4.27.4&#8243; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;22px&#8221; header_font=&#8221;||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_2_line_height=&#8221;1.2em&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; header_4_text_color=&#8221;#FFFFFF&#8221; header_5_text_color=&#8221;#FFFFFF&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; max_width=&#8221;100%&#8221; module_alignment=&#8221;left&#8221; custom_padding=&#8221;|||180px|false|false&#8221; custom_padding_tablet=&#8221;|12%||12%|false|false&#8221; custom_padding_phone=&#8221;|||12%|false|false&#8221; custom_padding_last_edited=&#8221;on|desktop&#8221; animation_direction=&#8221;top&#8221; hover_transition_duration=&#8221;0ms&#8221; header_2_line_height_tablet=&#8221;&#8221; header_2_line_height_phone=&#8221;1em&#8221; header_2_line_height_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><strong>Lorem ipsum dolor sit amet<\/strong><\/h2>\n<p>Stem cells and their immediate environment, also called stem cell niche, are critical for the growth and continuous renewal of our organs, and are also key for new growth and repair during regeneration. 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text_text_color=&#8221;#FFFFFF&#8221; text_line_height=&#8221;1.25em&#8221; header_font=&#8221;||||||||&#8221; header_4_font=&#8221;|700||on|||||&#8221; header_4_font_size=&#8221;16px&#8221; header_4_letter_spacing=&#8221;1px&#8221; header_4_line_height=&#8221;1.5em&#8221; background_layout=&#8221;dark&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong>Lab Address <\/strong><br \/>One Gustave L. Levy Place<br \/>Annenberg<br \/>New York, NY 10029<\/p>\n<p><strong>Mailing Address <\/strong><\/p>\n<p>Lab Name<br \/> Icahn School of Medicine <br \/>at Mount Sinai<br \/><span style=\"font-size: 16px\">One Gustave L. Levy Place<br \/><\/span><span style=\"font-size: 16px\">Annenberg<br \/><\/span><span style=\"font-size: 16px\">New York, NY 10029<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Header Title Description &#8211; Section &#8211; Header &#8211; Fullwidth Slider &#8221; module_id=&#8221;header-title-description-slider-section1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;rgba(0,174,239,0.09)&#8221; background_enable_color=&#8221;off&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/gulatilab-2\/wp-content\/uploads\/sites\/579\/2022\/07\/ai-002-1.jpg&#8221; parallax=&#8221;on&#8221; custom_padding=&#8221;||||false|false&#8221; bottom_divider_style=&#8221;ramp2&#8243; bottom_divider_color=&#8221;#FFFFFF&#8221; bottom_divider_height=&#8221;11vw&#8221; disabled=&#8221;on&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_slider arrows_custom_color=&#8221;#D80B8C&#8221; dot_nav_custom_color=&#8221;#D80B8C&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_slide heading=&#8221;One&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; header_text_align=&#8221;left&#8221; body_text_align=&#8221;left&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/gulatilab-2\/wp-content\/uploads\/sites\/579\/2022\/07\/ai-002-1.jpg&#8221; background_enable_image=&#8221;on&#8221; text_orientation=&#8221;left&#8221; custom_padding=&#8221;|||80px|false|false&#8221; global_colors_info=&#8221;{}&#8221; sticky_transition=&#8221;on&#8221;]<\/p>\n<p>Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n<p>[\/et_pb_slide][et_pb_slide heading=&#8221;Two&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; header_text_align=&#8221;left&#8221; body_text_align=&#8221;left&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/gulatilab-2\/wp-content\/uploads\/sites\/579\/2022\/07\/ai-002-1.jpg&#8221; background_enable_image=&#8221;on&#8221; text_orientation=&#8221;left&#8221; custom_padding=&#8221;|||80px|false|false&#8221; global_colors_info=&#8221;{}&#8221; sticky_transition=&#8221;on&#8221;]<\/p>\n<p>Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n<p>[\/et_pb_slide][et_pb_slide heading=&#8221;Three&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; header_text_align=&#8221;left&#8221; body_text_align=&#8221;left&#8221; background_image=&#8221;https:\/\/labs.icahn.mssm.edu\/gulatilab-2\/wp-content\/uploads\/sites\/579\/2022\/07\/ai-002-1.jpg&#8221; background_enable_image=&#8221;on&#8221; text_orientation=&#8221;left&#8221; custom_padding=&#8221;|||80px|false|false&#8221; global_colors_info=&#8221;{}&#8221; sticky_transition=&#8221;on&#8221;]<\/p>\n<p>Our current research focuses on birth of the hair follicle niche, growth control and regeneration, and tissue regression and reorganization.<\/p>\n<p>[\/et_pb_slide][\/et_pb_fullwidth_slider][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Translational Skin Research at the Intersection of Immunology and OncologyLorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. 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